Research Output per year
Research Output
2020
Pharmacokinetics of platinum and safety evaluation of carboplatin-impregnated calcium sulfate hemihydrate beads after implantation in healthy cats
Maxwell, E. A., Phillips, H., Clark-Price, S. C., Vieson, M. D., Selmic, L. E., Schaeffer, D. J. & Fan, T. M., Jan 1 2020, (Accepted/In press) In : Veterinary Surgery.Research output: Contribution to journal › Article
Understanding and Modeling Metastasis Biology to Improve Therapeutic Strategies for Combating Osteosarcoma Progression
Fan, T. M., Roberts, R. D. & Lizardo, M. M., Jan 31 2020, In : Frontiers in Oncology. 10, 13.Research output: Contribution to journal › Review article
Open Access
2019
EVALUATING THE CLINICAL AND PHYSIOLOGICAL EFFECTS OF LONG-TERM ULTRAVIOLET B RADIATION ON RABBITS (ORYCTOLAGUS CUNICULUS)
Watson, M. K., Mitchell, M. A., Stern, A. W., Labelle, A. L., Joslyn, S., Fan, T. M., Cavaretta, M., Kohles, M. & Marshall, K., Jan 2019, In : Journal of Exotic Pet Medicine. 28, p. 43-55 13 p.Research output: Contribution to journal › Article
Global analysis of osteosarcoma lipidomes reveal altered lipid profiles in metastatic versus nonmetastatic cells
Roy, J., Dibaeinia, P., Fan, T. M., Sinha, S. & Das, A., Jan 1 2019, In : Journal of Lipid Research. 60, 2, p. 375-387 13 p.Research output: Contribution to journal › Article
Immunohistochemical characterization of procaspase-3 overexpression as a druggable target with PAC-1, a procaspase-3 activator, in canine and human brain cancers
Schlein, L. J., Fadl-Alla, B., Pondenis, H. C., Lezmi, S., Eberhart, C. G., LeBlanc, A. K., Dickinson, P. J., Hergenrother, P. J. & Fan, T. M., Jan 1 2019, In : Frontiers in Oncology. 9, FEB, 96.Research output: Contribution to journal › Article
Open Access
Overexpression of prostate specific membrane antigen by canine hemangiosarcoma cells provides opportunity for the molecular detection of disease burdens within hemorrhagic body cavity effusions
Dowling, M., Samuelson, J., Fadl-Alla, B., Pondenis, H. C., Byrum, M., Barger, A. M. & Fan, T. M., Jan 2019, In : PloS one. 14, 1, e0210297.Research output: Contribution to journal › Article
Provocative questions in osteosarcoma basic and translational biology: A report from the Children's Oncology Group
Roberts, R. D., Lizardo, M. M., Reed, D. R., Hingorani, P., Glover, J., Allen-Rhoades, W., Fan, T., Khanna, C., Sweet-Cordero, E. A., Cash, T., Bishop, M. W., Hegde, M., Sertil, A. R., Koelsche, C., Mirabello, L., Malkin, D., Sorensen, P. H., Meltzer, P. S., Janeway, K. A., Gorlick, R. & 1 others, , Oct 15 2019, In : Cancer. 125, 20, p. 3514-3525 12 p.Research output: Contribution to journal › Review article
2018
Albumin as a "trojan Horse" for polymeric nanoconjugate transendothelial transport across tumor vasculatures for improved cancer targeting
Yin, Q., Tang, L., Cai, K., Yang, X., Yin, L., Zhang, Y., Dobrucki, L. W., Helferich, W. G., Fan, T. M. & Cheng, J., May 2018, In : Biomaterials Science. 6, 5, p. 1189-1200 12 p.Research output: Contribution to journal › Article
Antitumorigenic Properties of Omega-3 Endocannabinoid Epoxides
Roy, J., Watson, J. E., Hong, I. S., Fan, T. M. & Das, A., Jul 12 2018, In : Journal of Medicinal Chemistry. 61, 13, p. 5569-5579 11 p.Research output: Contribution to journal › Article
In vitro chemosensitivity of feline injection site-associated sarcoma cell lines to carboplatin
Maxwell, E. A., Phillips, H., Schaeffer, D. J. & Fan, T. M., Feb 1 2018, In : Veterinary Surgery. 47, 2, p. 219-226 8 p.Research output: Contribution to journal › Article
NCI comparative oncology program testing of non-camptothecin indenoisoquinoline topoisomerase I inhibitors in naturally occurring canine lymphoma
Burton, J. H., Mazcko, C., LeBlanc, A., Covey, J. M., Ji, J., Kinders, R. J., Parchment, R. E., Khanna, C., Paoloni, M., Lana, S., Weishaar, K., London, C., Kisseberth, W., Krick, E., Vail, D., Childress, M., Bryan, J. N., Barber, L., Ehrhart, E. J., Kent, M. & 11 others, , Dec 1 2018, In : Clinical Cancer Research. 24, 23, p. 5830-5840 11 p.Research output: Contribution to journal › Article
Of Mice, Dogs, Pigs, and Men: Choosing the Appropriate Model for Immuno-Oncology Research
Overgaard, N. H., Fan, T. M., Schachtschneider, K. M., Principe, D. R., Schook, L. B. & Jungersen, G., Dec 31 2018, In : ILAR Journal. 59, 3, p. 247-262 16 p.Research output: Contribution to journal › Review article
Rabacfosadine for relapsed canine B-cell lymphoma: Efficacy and adverse event profiles of 2 different doses
Saba, C. F., Vickery, K. R., Clifford, C. A., Burgess, K. E., Phillips, B., Vail, D. M., Wright, Z. M., Morges, M. A., Fan, T. M. & Thamm, D. H., Mar 2018, In : Veterinary and comparative oncology. 16, 1, p. E76-E82Research output: Contribution to journal › Article
Simulation of spatial diffusion of platinum from carboplatin-impregnated calcium sulfate hemihydrate beads by use of an agarose gelatin tissue phantom
Phillips, H., Maxwell, E. A., Schaeffer, D. J. & Fan, T. M., Jun 2018, In : American journal of veterinary research. 79, 6, p. 592-599 8 p.Research output: Contribution to journal › Article
Surveillance of Cancer Stem Cell Plasticity Using an Isoform-Selective Fluorescent Probe for Aldehyde Dehydrogenase 1A1
Anorma, C., Hedhli, J., Bearrood, T. E., Pino, N. W., Gardner, S. H., Inaba, H., Zhang, P., Li, Y., Feng, D., Dibrell, S. E., Kilian, K. A., Dobrucki, L. W., Fan, T. M. & Chan, J., Aug 22 2018, In : ACS Central Science. 4, 8, p. 1045-1055 11 p.Research output: Contribution to journal › Article
Tunable Stability of Imidazotetrazines Leads to a Potent Compound for Glioblastoma
Svec, R. L., Furiassi, L., Skibinski, C. G., Fan, T. M., Riggins, G. J. & Hergenrother, P. J., Nov 16 2018, In : ACS chemical biology. 13, 11, p. 3206-3216 11 p.Research output: Contribution to journal › Article
2017
Alternating Rabacfosadine/Doxorubicin: Efficacy and Tolerability in Naïve Canine Multicentric Lymphoma
Thamm, D. H., Vail, D. M., Post, G. S., Fan, T. M., Phillips, B. S., Axiak-Bechtel, S., Elmslie, R. S., Klein, M. K. & Ruslander, D. A., May 1 2017, In : Journal of veterinary internal medicine. 31, 3, p. 872-878 7 p.Research output: Contribution to journal › Article
Cancer Patients
Fan, T. M., Apr 28 2017, Veterinary Anesthesia and Analgesia: The Fifth Edition of Lumb and Jones. Wiley, p. 993-1003 11 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
Combinatorial Discovery of Defined Substrates That Promote a Stem Cell State in Malignant Melanoma
Zhang, D., Lee, J., Sun, M. B., Pei, Y., Chu, J., Gillette, M. U., Fan, T. M. & Kilian, K. A., May 24 2017, In : ACS Central Science. 3, 5, p. 381-393 13 p.Research output: Contribution to journal › Article
Comparative proteomic investigation of metastatic and non-metastatic osteosarcoma cells of human and canine origin
Roy, J., Wycislo, K. L., Pondenis, H., Fan, T. M. & Das, A., Sep 2017, In : PloS one. 12, 9, e0183930.Research output: Contribution to journal › Article
Melanoma topology reveals a stem-like phenotype that promotes angiogenesis
Lee, J., Abdeen, A. A., Hedhli, J., Wycislo, K. L., Dobrucki, I. T., Fan, T. M., Dobrucki, L. W. & Kilian, K. A., Jan 1 2017, In : Science Advances. 3, 10, e1701350.Research output: Contribution to journal › Article
Osteosarcoma enters a post genomic era with in silico opportunities: Generation of the High Dimensional Database for facilitating sarcoma biology research: A report from the Children's Oncology Group and the QuadW Foundation
for the COG Osteosarcoma Biology Group, Jul 2017, In : PloS one. 12, 7, e0181204.Research output: Contribution to journal › Article
Pharmacokinetics and derivation of an anticancer dosing regimen for the novel anti-cancer agent isobutyl-deoxynyboquinone (IB-DNQ), a NQO1 bioactivatable molecule, in the domestic felid species
Lundberg, A. P., Francis, J. M., Pajak, M., Parkinson, E. I., Wycislo, K. L., Rosol, T. J., Brown, M. E., London, C. A., Dirikolu, L., Hergenrother, P. J. & Fan, T. M., Apr 1 2017, In : Investigational New Drugs. 35, 2, p. 134-144 11 p.Research output: Contribution to journal › Article
Selective in vivo metabolic cell-labeling-mediated cancer targeting
Wang, H., Wang, R., Cai, K., He, H., Liu, Y., Yen, J., Wang, Z., Xu, M., Sun, Y., Zhou, X., Yin, Q., Tang, L., Dobrucki, I. T., Dobrucki, L. W., Chaney, E. J., Boppart, S. A., Fan, T. M., Lezmi, S., Chen, X., Yin, L. & 1 others, , Apr 1 2017, In : Nature chemical biology. 13, 4, p. 415-424 10 p.Research output: Contribution to journal › Article
Synergistic and targeted therapy with a procaspase-3 activator and temozolomide extends survival in glioma rodent models and is feasible for the treatment of canine malignant glioma patients
Joshi, A. D., Botham, R. C., Schlein, L. J., Roth, H. S., Mangraviti, A., Borodovsky, A., Tyler, B., Joslyn, S., Looper, J. S., Podell, M., Fan, T. M., Hergenrother, P. J. & Riggins, G. J., Jan 1 2017, In : Oncotarget. 8, 46, p. 80124-80138 15 p.Research output: Contribution to journal › Article
2016
Cancer biology
Fan, T. M., Aug 19 2016, Small Animal Cytologic Diagnosis. Barger, A. M. & MacNeill, A. (eds.). CRC Press, p. 47-58 12 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
Creation of an NCI comparative brain tumor consortium: Informing the translation of new knowledge from canine to human brain tumor patients
Leblanc, A. K., Mazcko, C., Brown, D. E., Koehler, J. W., Miller, A. D., Miller, C. R., Bentley, R. T., Packer, R. A., Breen, M., Boudreau, C. E., Levine, J. M., Simpson, R. M., Halsey, C., Kisseberth, W., Rossmeisl, J. H., Dickinson, P. J., Fan, T. M., Corps, K., Aldape, K., Puduvalli, V. & 2 others, , Sep 1 2016, In : Neuro-Oncology. 18, 9, p. 1209-1218 10 p.Research output: Contribution to journal › Review article
Diagnosis and ultrasonographic appearance of hepatic metastasis in six cases of canine appendicular osteosarcoma (2005-2013)
Cesario, L., Garrett, L. D., Barger, A. M., O'Brien, R. T. & Fan, T. M., May 1 2016, In : Australian veterinary journal. 94, 5, p. 160-165 6 p.Research output: Contribution to journal › Article
Downregulation of CXCR4 Expression and Functionality After Zoledronate Exposure in Canine Osteosarcoma
Byrum, M. L., Pondenis, H. C., Fredrickson, R. L., Wycislo, K. L. & Fan, T. M., Jul 1 2016, In : Journal of veterinary internal medicine. 30, 4, p. 1187-1196 10 p.Research output: Contribution to journal › Article
Interfacial geometry dictates cancer cell tumorigenicity
Lee, J., Abdeen, A. A., Wycislo, K. L., Fan, T. M. & Kilian, K. A., Aug 1 2016, In : Nature Materials. 15, 8, p. 856-862 7 p.Research output: Contribution to journal › Article
mTOR inhibition mitigates enhanced mRNA translation associated with the metastatic phenotype of osteosarcoma cells in vivo
Morrow, J. J., Mendoza, A., Koyen, A., Lizardo, M. M., Ren, L., Waybright, T. J., Hansen, R. J., Gustafson, D. L., Zhou, M., Fan, T. M., Scacheri, P. C. & Khanna, C., Dec 15 2016, In : Clinical Cancer Research. 22, 24, p. 6129-6141 13 p.Research output: Contribution to journal › Article
Pamidronate functionalized nanoconjugates for targeted therapy of focal skeletal malignant osteolysis
Yin, Q., Tang, L., Cai, K., Tong, R., Sternberg, R., Yang, X., Dobrucki, L. W., Borst, L. B., Kamstock, D., Song, Z., Helferich, W. G., Cheng, J. & Fan, T. M., Aug 9 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 32, p. E4601-E4609Research output: Contribution to journal › Article
Perspectives from man's best friend: National academy of medicine's workshop on comparative oncology
Leblanc, A. K., Breen, M., Choyke, P., Dewhirst, M., Fan, T. M., Gustafson, D. L., Helman, L. J., Kastan, M. B., Knapp, D. W., Levin, W. J., London, C., Mason, N., Mazcko, C., Olson, P. N., Page, R., Teicher, B. A., Thamm, D. H., Trent, J. M., Vail, D. M. & Khanna, C., Feb 3 2016, In : Science Translational Medicine. 8, 324, 324ps5.Research output: Contribution to journal › Review article
Pet scans
Fan, T. M., Le Blanc, A. K. & Mason, N., Apr 2016, In : Scientist. 30, 4Research output: Contribution to journal › Comment/debate
Pharmacokinetics of orally administered low-dose rapamycin in healthy dogs
Larson, J. C., Allstadt, S. D., Fan, T. M., Khanna, C., Lunghofer, P. J., Hansen, R. J., Gustafson, D. L. PHD., Legendre, A. M., Galyon, G. D., LeBlanc, A. K. & Martin-Jimenez, T., Jan 2016, In : American journal of veterinary research. 77, 1, p. 65-71 7 p.Research output: Contribution to journal › Article
Small-molecule procaspase-3 activation sensitizes cancer to treatment with diverse chemotherapeutics
Botham, R. C., Roth, H. S., Book, A. P., Roady, P. J., Fan, T. M. & Hergenrother, P. J., Aug 24 2016, In : ACS Central Science. 2, 8, p. 545-559 15 p.Research output: Contribution to journal › Article
The combination of vemurafenib and procaspase-3 activation is synergistic in mutant BRAF melanomas
Peh, J., Fan, T. M., Wycislo, K. L., Roth, H. S. & Hergenrother, P. J., Aug 2016, In : Molecular Cancer Therapeutics. 15, 8, p. 1859-1869 11 p.Research output: Contribution to journal › Article
Zoledronate-Associated Osteonecrosis of the Jaw in a Dog with Appendicular Osteosarcoma
Lundberg, A. P., Roady, P. J., Somrak, A. J., Howes, M. E. & Fan, T. M., Jul 1 2016, In : Journal of veterinary internal medicine. 30, 4, p. 1235-1240 6 p.Research output: Contribution to journal › Article
2015
Alkylation and carbamylation effects of lomustine and its major metabolites and MGMT expression in canine cells
Chakkath, T., Lavergne, S., Fan, T. M., Bunick, D. & Dirikolu, L., Jun 1 2015, In : Veterinary Sciences. 2, 2, p. 52-68 17 p.Research output: Contribution to journal › Article
A Small Molecule that Induces Intrinsic Pathway Apoptosis with Unparalleled Speed
Palchaudhuri, R., Lambrecht, M. J., Botham, R. C., Partlow, K. C., van Ham, T. J., Putt, K. S., Nguyen, L. T., Kim, S. H., Peterson, R. T., Fan, T. M. & Hergenrother, P. J., Dec 1 2015, In : Cell Reports. 13, 9, p. 2027-2036 10 p.Research output: Contribution to journal › Article
A summary of the osteosarcoma banking efforts: A report from the Children's Oncology Group and the QuadW Foundation
Glover, J., Krailo, M., Tello, T., Marina, N., Janeway, K., Barkauskas, D., Fan, T. M., Gorlick, R. & Khanna, C., Mar 1 2015, In : Pediatric Blood and Cancer. 62, 3, p. 450-455 6 p.Research output: Contribution to journal › Article
Biological behaviour of canine mandibular osteosarcoma. A retrospective study of 50 cases (1999-2007)
Coyle, V. J., Rassnick, K. M., Borst, L. B., Rodriguez, C. O., Northrup, N. C., Fan, T. M. & Garrett, L. D., Jun 1 2015, In : Veterinary and comparative oncology. 13, 2, p. 89-97 9 p.Research output: Contribution to journal › Article
Canine osteosarcoma cell lines from patients with differing serum alkaline phosphatase concentrations display no behavioural differences in vitro
Holmes, K. E., Thompson, V., Piskun, C. M., Kohnken, R. A., Huelsmeyer, M. K., Fan, T. M. & Stein, T. J., Sep 1 2015, In : Veterinary and comparative oncology. 13, 3, p. 166-175 10 p.Research output: Contribution to journal › Article
Comparative aspects of osteosarcoma pathogenesis in humans and dogs
Fan, T. M. & Khanna, C., Sep 1 2015, In : Veterinary Sciences. 2, 3, p. 210-230 21 p.Research output: Contribution to journal › Review article
Direct Capture of Functional Proteins from Mammalian Plasma Membranes into Nanodiscs
Roy, J., Pondenis, H., Fan, T. M. & Das, A., Oct 20 2015, In : Biochemistry. 54, 41, p. 6299-6302 4 p.Research output: Contribution to journal › Article
Expression of Nociceptive Ligands in Canine Osteosarcoma
Shor, S., Fadl-Alla, B. A., Pondenis, H. C., Zhang, X., Wycislo, K. L., Lezmi, S. & Fan, T. M., Jan 1 2015, In : Journal of veterinary internal medicine. 29, 1, p. 268-275 8 p.Research output: Contribution to journal › Article
Removal of metabolic liabilities enables development of derivatives of procaspase-activating compound 1 (PAC-1) with improved pharmacokinetics
Roth, H. S., Botham, R. C., Schmid, S. C., Fan, T. M., Dirikolu, L. & Hergenrother, P. J., May 14 2015, In : Journal of Medicinal Chemistry. 58, 9, p. 4046-4065 20 p.Research output: Contribution to journal › Article
Targeting tumor vasculature with aptamer-functionalized doxorubicin-polylactide nanoconjugates for enhanced cancer therapy
Tang, L., Tong, R., Coyle, V. J., Yin, Q., Pondenis, H., Borst, L. B., Cheng, J. & Fan, T. M., May 26 2015, In : ACS Nano. 9, 5, p. 5072-5081 10 p.Research output: Contribution to journal › Article
The Association of Endothelin-1 Signaling with Bone Alkaline Phosphatase Expression and Protumorigenic Activities in Canine Osteosarcoma
Neumann, Z. L., Pondenis, H. C., Masyr, A., Byrum, M. L., Wycislo, K. L. & Fan, T. M., Nov 1 2015, In : Journal of veterinary internal medicine. 29, 6, p. 1584-1594 11 p.Research output: Contribution to journal › Article
The Immunotherapy of Canine Osteosarcoma: A Historical and Systematic Review
Wycislo, K. L. & Fan, T. M., May 1 2015, In : Journal of veterinary internal medicine. 29, 3, p. 759-769 11 p.Research output: Contribution to journal › Article