If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Fingerprint is based on mining the text of the expert's scholarly documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 3 Similar Profiles
Zinc Fingers Medicine & Life Sciences
Recombinases Medicine & Life Sciences
Genes Chemical Compounds
Clustered Regularly Interspaced Short Palindromic Repeats Medicine & Life Sciences
Genome Medicine & Life Sciences
Dependovirus Medicine & Life Sciences
Zinc Chemical Compounds
Technology Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2006 2019

CRISPR-Cas9-Mediated Genome Editing Increases Lifespan and Improves Motor Deficits in a Huntington's Disease Mouse Model

Ekman, F. K., Ojala, D. S., Adil, M. M., Lopez, P. A., Schaffer, D. V. & Gaj, T., Sep 6 2019, In : Molecular Therapy - Nucleic Acids. 17, p. 829-839 11 p.

Research output: Contribution to journalArticle

Open Access
Clustered Regularly Interspaced Short Palindromic Repeats
Huntington Disease
Trinucleotide Repeat Expansion
Neurodegenerative Diseases
Genes

A Hypothalamic Switch for REM and Non-REM Sleep

Chen, K. S., Xu, M., Zhang, Z., Chang, W. C., Gaj, T., Schaffer, D. V. & Dan, Y., Mar 7 2018, In : Neuron. 97, 5, p. 1168-1176.e4

Research output: Contribution to journalArticle

REM Sleep
Eye Movements
Sleep
Neurons
Hypothalamus

hPSC-Derived Striatal Cells Generated Using a Scalable 3D Hydrogel Promote Recovery in a Huntington Disease Mouse Model

Adil, M. M., Gaj, T., Rao, A. T., Kulkarni, R. U., Fuentes, C. M., Ramadoss, G. N., Ekman, F. K., Miller, E. W. & Schaffer, D. V., May 8 2018, In : Stem Cell Reports. 10, 5, p. 1481-1491 11 p.

Research output: Contribution to journalArticle

Corpus Striatum
Pluripotent Stem Cells
Hydrogel
Huntington Disease
Stem cells

Innovations in CRISPR technology

Brooks, A. K. & Gaj, T., Aug 2018, In : Current Opinion in Biotechnology. 52, p. 95-101 7 p.

Research output: Contribution to journalReview article

Clustered Regularly Interspaced Short Palindromic Repeats
Innovation
Technology
Genes
Gene therapy

Manufacturing and delivering genome-editing proteins

Liu, J., Liang, Y. J., Ren, P. L. & Gaj, T., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 253-273 21 p. (Methods in Molecular Biology; vol. 1867).

Research output: Chapter in Book/Report/Conference proceedingChapter

Ribonucleoproteins
Dependovirus
Zinc Fingers
Transgenes
Proteins