Susan A Martinis

1987 …2019
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  • 6 Similar Profiles
Amino Acyl-tRNA Synthetases Medicine & Life Sciences
Aminoacylation Medicine & Life Sciences
Transfer RNA Medicine & Life Sciences
Amino Acids Medicine & Life Sciences
Catalytic Domain Medicine & Life Sciences
Escherichia coli Medicine & Life Sciences
RNA, Transfer, Leu Medicine & Life Sciences
Enzymes Medicine & Life Sciences

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Research Output 1987 2019

Nontranslational function of leucyl-tRNA synthetase regulates myogenic differentiation and skeletal muscle regeneration

Son, K., You, J. S., Yoon, M. S., Dai, C., Kim, J. H., Khanna, N., Banerjee, A., Martinis, S. A., Han, G., Han, J. M., Kim, S. & Chen, J., May 1 2019, In : Journal of Clinical Investigation. 129, 5, p. 2088-2093 6 p.

Research output: Contribution to journalArticle

Open Access
Amino Acyl-tRNA Synthetases
Regeneration
Skeletal Muscle
Muscle Development
Transfer RNA Aminoacylation

Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy

Stephen, J., Nampoothiri, S., Banerjee, A., Tolman, N. J., Penninger, J. M., Elling, U., Agu, C. A., Burke, J. D., Devadathan, K., Kannan, R., Huang, Y., Steinbach, P. J., Martinis, S. A., Gahl, W. A. & Malicdan, M. C. V., Apr 1 2018, In : Human Genetics. 137, 4, p. 293-303 11 p.

Research output: Contribution to journalArticle

Valine-tRNA Ligase
Microcephaly
Atrophy
Seizures
Mutation

Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction

Kim, J. H., Lee, C., Lee, M., Wang, H., Kim, K., Park, S. J., Yoon, I., Jang, J., Zhao, H., Kim, H. K., Kwon, N. H., Jeong, S. J., Yoo, H. C., Kim, J. H., Yang, J. S., Lee, M. Y., Lee, C. W., Yun, J., Oh, S. J., Kang, J. S. & 6 others, Martinis, S. A., Hwang, K. Y., Guo, M., Han, G., Han, J. M. & Kim, S., Dec 1 2017, In : Nature communications. 8, 1, 732.

Research output: Contribution to journalArticle

Amino Acyl-tRNA Synthetases
leucine
Leucine
cancer
catalytic activity

Isolation of bacterial compartments to track movement of protein synthesis factors

Zhao, H. & Martinis, S. A., Jan 15 2017, In : Methods. 113, p. 120-126 7 p.

Research output: Contribution to journalArticle

Amino Acyl-tRNA Synthetases
Transfer RNA
Fractionation
Proteins
Membranes

Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight into the Leucyl-tRNA Synthetase Editing Mechanism

Zhao, H., Palencia, A., Seiradake, E., Ghaemi, Z., Cusack, S., Luthey-Schulten, Z. & Martinis, S., Oct 16 2015, In : ACS chemical biology. 10, 10, p. 2277-2285 9 p.

Research output: Contribution to journalArticle

Amino Acyl-tRNA Synthetases
Transfer RNA
Tyrosine
Catalytic Domain
RNA, Transfer, Leu