Susan A Martinis

1987 …2018
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Fingerprint is based on mining the text of the expert's scholarly documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 3 Similar Profiles
Amino Acyl-tRNA Synthetases Medicine & Life Sciences
Aminoacylation Medicine & Life Sciences
Transfer RNA Medicine & Life Sciences
Amino Acids Medicine & Life Sciences
Catalytic Domain Medicine & Life Sciences
Escherichia coli Medicine & Life Sciences
RNA, Transfer, Leu Medicine & Life Sciences
Enzymes Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1987 2018

Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy

Stephen, J., Nampoothiri, S., Banerjee, A., Tolman, N. J., Penninger, J. M., Elling, U., Agu, C. A., Burke, J. D., Devadathan, K., Kannan, R., Huang, Y., Steinbach, P. J., Martinis, S. A., Gahl, W. A. & Malicdan, M. C. V., Apr 1 2018, In : Human Genetics. 137, 4, p. 293-303 11 p.

Research output: Contribution to journalArticle

Valine-tRNA Ligase
Microcephaly
Atrophy
Seizures
Mutation

Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction

Kim, J. H., Lee, C., Lee, M., Wang, H., Kim, K., Park, S. J., Yoon, I., Jang, J., Zhao, H., Kim, H. K., Kwon, N. H., Jeong, S. J., Yoo, H. C., Kim, J. H., Yang, J. S., Lee, M. Y., Lee, C. W., Yun, J., Oh, S. J., Kang, J. S. & 6 othersMartinis, S. A., Hwang, K. Y., Guo, M., Han, G., Han, J. M. & Kim, S., Dec 1 2017, In : Nature Communications. 8, 1, 732.

Research output: Contribution to journalArticle

Amino Acyl-tRNA Synthetases
leucine
Leucine
cancer
catalytic activity

Isolation of bacterial compartments to track movement of protein synthesis factors

Zhao, H. & Martinis, S. A., Jan 15 2017, In : Methods. 113, p. 120-126 7 p.

Research output: Contribution to journalArticle

Amino Acyl-tRNA Synthetases
Transfer RNA
Fractionation
Proteins
Membranes

Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight into the Leucyl-tRNA Synthetase Editing Mechanism

Zhao, H., Palencia, A., Seiradake, E., Ghaemi, Z., Cusack, S., Luthey-Schulten, Z. & Martinis, S., Oct 16 2015, In : ACS chemical biology. 10, 10, p. 2277-2285 9 p.

Research output: Contribution to journalArticle

Amino Acyl-tRNA Synthetases
Transfer RNA
Tyrosine
Catalytic Domain
RNA, Transfer, Leu

Non-catalytic regulation of gene expression by aminoacyl-tRNA synthetases.

Yao, P., Poruri, K., Martinis, S. A. & Fox, P. L., 2014, In : Topics in Current Chemistry. 344, p. 167-187 21 p.

Research output: Contribution to journalReview article

Amino Acyl-tRNA Synthetases
Gene expression
Genes
Yeast
Messenger RNA