Sumiti Vinayak

20032020
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Alleles Medicine & Life Sciences
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Research Output 2003 2020

Genetic Manipulation of Cryptosporidium parvum with CRISPR/Cas9

Sateriale, A., Pawlowic, M., Vinayak, S., Brooks, C. & Striepen, B., Jan 1 2020, Methods in Molecular Biology. Humana Press Inc., p. 219-228 10 p. (Methods in Molecular Biology; vol. 2052).

Research output: Chapter in Book/Report/Conference proceedingChapter

Clustered Regularly Interspaced Short Palindromic Repeats
Cryptosporidium parvum
Transfection
Infection

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

Baragaña, B., Forte, B., Choi, R., Hewitt, S. N., Bueren-Calabuig, J. A., Pisco, J. P., Peet, C., Dranow, D. M., Robinson, D. A., Jansen, C., Norcross, N. R., Vinayak, S., Anderson, M., Brooks, C. F., Cooper, C. A., Damerow, S., Delves, M., Dowers, K., Duffy, J., Edwards, T. E. & 57 others, Hallyburton, I., Horst, B. G., Hulverson, M. A., Ferguson, L., Jiménez-Díaz, M. B., Jumani, R. S., Lorimer, D. D., Love, M. S., Maher, S., Matthews, H., McNamara, C. W., Miller, P., O’Neill, S., Ojo, K. K., Osuna-Cabello, M., Pinto, E., Post, J., Riley, J., Rottmann, M., Sanz, L. M., Scullion, P., Sharma, A., Shepherd, S. M., Shishikura, Y., Simeons, F. R. C., Stebbins, E. E., Stojanovski, L., Straschil, U., Tamaki, F. K., Tamjar, J., Torrie, L. S., Vantaux, A., Witkowski, B., Wittlin, S., Yogavel, M., Zuccotto, F., Angulo-Barturen, I., Sinden, R., Baum, J., Gamo, F. J., Mäser, P., Kyle, D. E., Winzeler, E. A., Myler, P. J., Wyatt, P. G., Floyd, D., Matthews, D., Sharma, A., Striepen, B., Huston, C. D., Gray, D. W., Fairlamb, A. H., Pisliakov, A. V., Walpole, C., Read, K. D., Van Voorhis, W. C. & Gilbert, I. H., Apr 2 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 14, p. 7015-7020 6 p.

Research output: Contribution to journalArticle

Open Access
Lysine-tRNA Ligase
Cryptosporidium parvum
Cryptosporidiosis
Malaria
Pharmaceutical Preparations

A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis

Manjunatha, U. H., Vinayak, S., Zambriski, J. A., Chao, A. T., Sy, T., Noble, C. G., Bonamy, G. M. C., Kondreddi, R. R., Zou, B., Gedeck, P., Brooks, C. F., Herbert, G. T., Sateriale, A., Tandel, J., Noh, S., Lakshminarayana, S. B., Lim, S. H., Goodman, L. B., Bodenreider, C., Feng, G. & 6 others, Zhang, L., Blasco, F., Wagner, J., Leong, F. J., Striepen, B. & Diagana, T. T., Jun 15 2017, In : Nature. 546, 7658, p. 376-380 5 p.

Research output: Contribution to journalArticle

Cryptosporidiosis
Cryptosporidium
1-Phosphatidylinositol 4-Kinase
Pharmaceutical Preparations
Diarrhea

Bumped-kinase inhibitors for cryptosporidiosis therapy

Hulverson, M. A., Vinayak, S., Choi, R., Schaefer, D. A., Castellanos-Gonzalez, A., Vidadala, R. S. R., Brooks, C. F., Herbert, G. T., Betzer, D. P., Whitman, G. R., Sparks, H. N., Arnold, S. L. M., Rivas, K. L., Barrett, L. K., White, A. C., Maly, D. J., Riggs, M. W., Striepen, B., Van Voorhis, W. C. & Ojo, K. K., Jan 1 2017, In : Journal of Infectious Diseases. 215, 8, p. 1275-1284 10 p.

Research output: Contribution to journalArticle

Cryptosporidiosis
Cryptosporidium parvum
Phosphotransferases
High-Throughput Screening Assays
Therapeutics

Generating and maintaining transgenic Cryptosporidium parvum parasites

Pawlowic, M. C., Vinayak, S., Sateriale, A., Brooks, C. F. & Striepen, B., Aug 1 2017, In : Current Protocols in Microbiology. 2017, p. 20B.2.1-20B.2.32

Research output: Contribution to journalArticle

Cryptosporidium parvum
Cryptosporidium
Parasites
Cryptosporidiosis
Child Mortality