Sumiti Vinayak

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  • Bicyclic azetidines kill the diarrheal pathogen Cryptosporidium in mice by inhibiting parasite phenylalanyl-tRNA synthetase

    Vinayak, S., Jumani, R. S., Miller, P., Hasan, M. M., Mcleod, B. I., Tandel, J., Stebbins, E. E., Teixeira, J. E., Borrel, J., Gonse, A., Zhang, M., Yu, X., Wernimont, A., Walpole, C., Eckley, S., Love, M. S., Mcnamara, C. W., Sharma, M., Sharma, A., Scherer, C. A. & 6 others, Kato, N., Schreiber, S. L., Melillo, B., Striepen, B., Huston, C. D. & Comer, E., Sep 30 2020, In : Science Translational Medicine. 12, 563, p. eaba8412

    Research output: Contribution to journalArticlepeer-review

  • Genetic Manipulation of Cryptosporidium parvum with CRISPR/Cas9

    Sateriale, A., Pawlowic, M., Vinayak, S., Brooks, C. & Striepen, B., Jan 1 2020, Methods in Molecular Biology. Humana Press Inc., p. 219-228 10 p. (Methods in Molecular Biology; vol. 2052).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  • Recent advances in genetic manipulation of Cryptosporidium

    Vinayak, S., Nov 5 2020, In : Current Opinion in Microbiology. 58, p. 146-152 7 p.

    Research output: Contribution to journalReview articlepeer-review

  • Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

    Baragaña, B., Forte, B., Choi, R., Hewitt, S. N., Bueren-Calabuig, J. A., Pisco, J. P., Peet, C., Dranow, D. M., Robinson, D. A., Jansen, C., Norcross, N. R., Vinayak, S., Anderson, M., Brooks, C. F., Cooper, C. A., Damerow, S., Delves, M., Dowers, K., Duffy, J., Edwards, T. E. & 57 others, Hallyburton, I., Horst, B. G., Hulverson, M. A., Ferguson, L., Jiménez-Díaz, M. B., Jumani, R. S., Lorimer, D. D., Love, M. S., Maher, S., Matthews, H., McNamara, C. W., Miller, P., O’Neill, S., Ojo, K. K., Osuna-Cabello, M., Pinto, E., Post, J., Riley, J., Rottmann, M., Sanz, L. M., Scullion, P., Sharma, A., Shepherd, S. M., Shishikura, Y., Simeons, F. R. C., Stebbins, E. E., Stojanovski, L., Straschil, U., Tamaki, F. K., Tamjar, J., Torrie, L. S., Vantaux, A., Witkowski, B., Wittlin, S., Yogavel, M., Zuccotto, F., Angulo-Barturen, I., Sinden, R., Baum, J., Gamo, F. J., Mäser, P., Kyle, D. E., Winzeler, E. A., Myler, P. J., Wyatt, P. G., Floyd, D., Matthews, D., Sharma, A., Striepen, B., Huston, C. D., Gray, D. W., Fairlamb, A. H., Pisliakov, A. V., Walpole, C., Read, K. D., Van Voorhis, W. C. & Gilbert, I. H., Apr 2 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 14, p. 7015-7020 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis

    Manjunatha, U. H., Vinayak, S., Zambriski, J. A., Chao, A. T., Sy, T., Noble, C. G., Bonamy, G. M. C., Kondreddi, R. R., Zou, B., Gedeck, P., Brooks, C. F., Herbert, G. T., Sateriale, A., Tandel, J., Noh, S., Lakshminarayana, S. B., Lim, S. H., Goodman, L. B., Bodenreider, C., Feng, G. & 6 others, Zhang, L., Blasco, F., Wagner, J., Leong, F. J., Striepen, B. & Diagana, T. T., Jun 15 2017, In : Nature. 546, 7658, p. 376-380 5 p.

    Research output: Contribution to journalArticlepeer-review

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