Steven C Zimmerman

1983 …2019
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Dendrimers Chemical Compounds
Hydrogen bonds Chemical Compounds
Polymers Chemical Compounds
Hydrogen Bonding Medicine & Life Sciences
Hydrogen Medicine & Life Sciences
Complexation Chemical Compounds
Myotonic Dystrophy Medicine & Life Sciences
Molecules Chemical Compounds

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Research Output 1983 2019

Acid-Triggered, Acid-Generating, and Self-Amplifying Degradable Polymers

Miller, K. A., Morado, E. G., Samanta, S. R., Walker, B. A., Nelson, A. Z., Sen, S., Tran, D. T., Whitaker, D. J., Ewoldt, R. H., Braun, P. V. & Zimmerman, S. C., Feb 20 2019, In : Journal of the American Chemical Society. 141, 7, p. 2838-2842 5 p.

Research output: Contribution to journalArticle

Polymers
polymer
Acrolein
Degradation
Acetals

AQAMAN, a bisamidine-based inhibitor of toxic protein inclusions in neurons, ameliorates cytotoxicity in polyglutamine disease models

Hong, H., Koon, A. C., Chen, Z. S., Wei, Y., An, Y., Li, W., Lau, M. H. Y., Lau, K. F., Ngo, J. C. K., Wong, C. H., Au-Yeung, H. Y., Zimmerman, S. C. & Chan, H. Y. E., Jan 1 2019, In : Journal of Biological Chemistry. 294, 8, p. 2757-2770 14 p.

Research output: Contribution to journalArticle

Poisons
Cytotoxicity
Neurons
Proteins
Autophagy

Development of novel macrocyclic small molecules that target CTG trinucleotide repeats

Serrano, J. F., Lee, J. Y., Daniel Curet, L., Hagler, L. D., Bonson, S. E., Schuster, E. J. & Zimmerman, S. C., Jul 1 2019, In : Bioorganic and Medicinal Chemistry. 27, 13, p. 2978-2984 7 p.

Research output: Contribution to journalArticle

Acridines
Trinucleotide Repeats
Molecules
Calorimetry
Transcription

Intrinsically cell-penetrating multivalent and multitargeting ligands for myotonic dystrophy type 1

Lee, J. Y., Bai, Y., Chembazhi, U. V., Peng, S., Yum, K., Luu, L. M., Hagler, L. D., Serrano, J. F., Edwin Chan, H. Y., Kalsotra, A. & Zimmerman, S. C., Apr 30 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 18, p. 8709-8714 6 p.

Research output: Contribution to journalArticle

Myotonic Dystrophy
Ligands
Permeability
Cell-Penetrating Peptides
RNA

Polymeric "clickase" Accelerates the Copper Click Reaction of Small Molecules, Proteins, and Cells

Chen, J., Wang, J., Li, K., Wang, Y., Gruebele, M. H. W., Ferguson, A. L. & Zimmerman, S. C., Jun 19 2019, In : Journal of the American Chemical Society. 141, 24, p. 9693-9700 8 p.

Research output: Contribution to journalArticle

Copper
Alkynes
Azides
catalyst
copper