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Research Output

2020

Depixelation and enhancement of fiber bundle images by bundle rotation

Renteria, C., Suárez, J., Licudine, A. & Boppart, S. A., Jan 10 2020, In : Applied Optics. 59, 2, p. 536-544 9 p.

Research output: Contribution to journalArticle

Dynamic Tracking Algorithm for Time-Varying Neuronal Network Connectivity using Wide-Field Optical Image Video Sequences

Renteria, C., Liu, Y. Z., Chaney, E. J., Barkalifa, R., Sengupta, P. & Boppart, S. A., Dec 1 2020, In : Scientific reports. 10, 1, 2540.

Research output: Contribution to journalArticle

Open Access

Non-invasive monitoring of pharmacodynamics during the skin wound healing process using multimodal optical microscopy

Rico-Jimenez, J., Lee, J. H., Alex, A., Musaad, S., Chaney, E., Barkalifa, R., Olson, E., Adams, D., Marjanovic, M., Arp, Z. & Boppart, S. A., Apr 22 2020, In : BMJ Open Diabetes Research and Care. 8, 1, e000974.

Research output: Contribution to journalArticle

Open Access

Otitis Media Middle Ear Effusion Identification and Characterization Using an Optical Coherence Tomography Otoscope

Preciado, D., Nolan, R. M., Joshi, R., Krakovsky, G. M., Zhang, A., Pudik, N. A., Kumar, N. K., Shelton, R. L., Boppart, S. A. & Bauman, N. M., Jan 1 2020, (Accepted/In press) In : Otolaryngology - Head and Neck Surgery (United States).

Research output: Contribution to journalArticle

Two-photon microscope using a fiber-based approach for supercontinuum generation and light delivery to a small-footprint optical head

Zhao, Y., Maguluri, G., Daniel Ferguson, R., Tu, H., Paul, K., Boppart, S. A., Llano, D. A. & Iftimia, N., Feb 15 2020, In : Optics Letters. 45, 4, p. 909-912 4 p.

Research output: Contribution to journalArticle

2019

Automated sensorless single-shot closed-loop adaptive optics microscopy with feedback from computational adaptive optics

Iyer, R. R., Liu, Y. Z. & Boppart, S. A., Apr 29 2019, In : Optics Express. 27, 9, p. 12998-13014 17 p.

Research output: Contribution to journalArticle

Comparison between optical coherence tomographic and histopathologic appearances of artifacts caused by common surgical conditions and instrumentation

Cocca, C. J., Selmic, L. E., Samuelson, J., Huang, P. C., Wang, J. & Boppart, S. A., Nov 1 2019, In : Veterinary Surgery. 48, 8, p. 1361-1371 11 p.

Research output: Contribution to journalArticle

Detection of weak near-infrared optical imaging signals under ambient light by optical parametric amplification

Sun, Y., Tu, H., You, S., Zhang, C., Liu, Y. Z. & Boppart, S. A., Sep 1 2019, In : Optics Letters. 44, 17, p. 4391-4394 4 p.

Research output: Contribution to journalArticle

Digital staining through the application of deep neural networks to multi-modal multi-photon microscopy

Borhani, N., Bower, A. J., Boppart, S. A. & Psaltis, D., Mar 1 2019, In : Biomedical Optics Express. 10, 3, p. 1339-1350 12 p., 355205.

Research output: Contribution to journalArticle

Interstitial magnetic thermotherapy dosimetry based on shear wave magnetomotive optical coherence elastography

Huang, P. C., Chaney, E. J., Iyer, R. R., Spillman, D. R., Odintsov, B., Sobh, N. A. & Boppart, S. A., Jan 1 2019, In : Biomedical Optics Express. 10, 2, p. 539-551 13 p.

Research output: Contribution to journalArticle

Intra-operative imaging of surgical margins of canine soft tissue sarcoma using optical coherence tomography

Selmic, L. E., Samuelson, J., Reagan, J. K., Mesa, K. J., Driskell, E., Li, J., Marjanovic, M. & Boppart, S. A., Mar 2019, In : Veterinary and comparative oncology. 17, 1, p. 80-88 9 p.

Research output: Contribution to journalArticle

In vivo detection of endotracheal tube biofilms in intubated critical care patients using catheter-based optical coherence tomography

Dsouza, R., Spillman, D. R., Barkalifa, R., Monroy, G. L., Chaney, E. J., White, K. C. & Boppart, S. A., Jan 1 2019, (Accepted/In press) In : Journal of Biophotonics. e201800307.

Research output: Contribution to journalArticle

Label-free molecular profiling for identification of biomarkers in carcinogenesis using multimodal multiphoton imaging

Liu, Y., Tu, H., You, S., Chaney, E. J., Marjanovic, M. & Boppart, S. A., Jan 1 2019, In : Quantitative Imaging in Medicine and Surgery. 9, 5, p. 742-756 15 p.

Research output: Contribution to journalArticle

Label-free visualization and characterization of extracellular vesicles in breast cancer

You, S., Barkalifa, R., Chaney, E. J., Tu, H., Park, J., Sorrells, J. E., Sun, Y., Liu, Y. Z., Yang, L., Chen, D. Z., Marjanovic, M., Sinha, S. & Boppart, S. A., Nov 26 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 48, p. 24012-24018 7 p.

Research output: Contribution to journalArticle

Local wavefront mapping in tissue using computational adaptive optics OCT

South, F. A., Liu, Y. Z., Huang, P. C., Kohlfarber, T. & Boppart, S. A., Mar 1 2019, In : Optics Letters. 44, 5, p. 1186-1189 4 p.

Research output: Contribution to journalArticle

Real-time intraoperative diagnosis by deep neural network driven multiphoton virtual histology

You, S., Sun, Y., Yang, L., Park, J., Tu, H., Marjanovic, M., Sinha, S. & Boppart, S. A., Dec 17 2019, In : npj Precision Oncology. 3, 1, 33.

Research output: Contribution to journalArticle

Open Access

Simultaneous label-free autofluorescence and multi-harmonic imaging reveals in vivo structural and metabolic changes in murine skin

Lee, J. H., Rico-Jimenez, J. J., Zhang, C., Alex, A., Chaney, E. J., Barkalifa, R., Spillman, D. R., Marjanovic, M., Arp, Z., Hood, S. R. & Boppart, S. A., Oct 1 2019, In : Biomedical Optics Express. 10, 10, p. 5431-5444 14 p.

Research output: Contribution to journalArticle

Simultaneous label-free autofluorescence-multiharmonic microscopy and beyond

Boppart, S. A., You, S., Li, L., Chen, J. & Tu, H., Oct 1 2019, In : APL Photonics. 4, 10, 100901.

Research output: Contribution to journalArticle

Open Access

Tracking metabolic dynamics of apoptosis with high-speed two-photon fluorescence lifetime imaging microscopy

Bower, A. J., Sorrells, J. E., Li, J., Marjanovic, M., Barkalifa, R. & Boppart, S. A., Dec 1 2019, In : Biomedical Optics Express. 10, 12, p. 6408-6421 14 p.

Research output: Contribution to journalArticle

Video-rate multimodal multiphoton imaging and three-dimensional characterization of cellular dynamics in wounded skin

Li, J., Wilson, M. N., Bower, A. J., Marjanovic, M., Chaney, E. J., Barkalifa, R. & Boppart, S. A., Jan 1 2019, (Accepted/In press) In : Journal of Innovative Optical Health Sciences. 2050007.

Research output: Contribution to journalArticle

Open Access
2018

Biophotonics: The big picture

Marcu, L., Boppart, S. A., Hutchinson, M. R., Popp, J. & Wilson, B. C., Feb 2018, In : Journal of biomedical optics. 23, 2, 021103.

Research output: Contribution to journalArticle

Combined hardware and computational optical wavefront correction

South, F. A., Kurokawa, K., Liu, Z., Liu, Y. Z., Miller, D. T. & Boppart, S. A., Jun 1 2018, In : Biomedical Optics Express. 9, 6, p. 2562-2574 13 p., #322898.

Research output: Contribution to journalArticle

Complementary use of polarization-sensitive and standard OCT metrics for enhanced intraoperative differentiation of breast cancer

Wang, J., Xu, Y., Mesa, K. J., South, F. A., Chaney, E. J., Spillman, D. R., Barkalifa, R., Marjanovic, M., Carney, P. S., Higham, A. M., Liu, Z. G. & Boppart, S. A., Dec 1 2018, In : Biomedical Optics Express. 9, 12, p. 6519-6528 10 p., #346713.

Research output: Contribution to journalArticle

Direct Analysis of Pathogenic Structures Affixed to the Tympanic Membrane during Chronic Otitis Media

Monroy, G. L., Hong, W., Khampang, P., Porter, R. G., Novak, M. A., Spillman, D. R., Barkalifa, R., Chaney, E. J., Kerschner, J. E. & Boppart, S. A., Jul 1 2018, In : Otolaryngology - Head and Neck Surgery (United States). 159, 1, p. 117-126 10 p.

Research output: Contribution to journalArticle

Disintegration of simulated drinking water biofilms with arrays of microchannel plasma jets

Sun, P. P., Araud, E. M., Huang, C., Shen, Y., Monroy, G. L., Zhong, S., Tong, Z., Boppart, S. A., Eden, J. G. & Nguyen, T. H., Dec 1 2018, In : npj Biofilms and Microbiomes. 4, 1, 24.

Research output: Contribution to journalArticle

Economical and compact briefcase spectral-domain optical coherence tomography system for primary care and point-of-care applications

Dsouza, R., Won, J., Monroy, G. L., Spillman, D. R. & Boppart, S. A., Sep 1 2018, In : Journal of biomedical optics. 23, 9, 096003.

Research output: Contribution to journalArticle

Effect of divalent ions and a polyphosphate on composition, structure, and stiffness of simulated drinking water biofilms

Shen, Y., Huang, P. C., Huang, C., Sun, P., Monroy, G. L., Wu, W., Lin, J., Espinosa-Marzal, R. M., Boppart, S. A., Liu, W. T. & Nguyen, T. H., Dec 1 2018, In : npj Biofilms and Microbiomes. 4, 1, 15.

Research output: Contribution to journalArticle

High-speed imaging of transient metabolic dynamics using two-photon fluorescence lifetime imaging microscopy

Bower, A. J., Li, J., Chaney, E. J., Marjanovic, M., Spillman, D. R. & Boppart, S. A., Oct 20 2018, In : Optica. 5, 10, p. 1290-1296 7 p.

Research output: Contribution to journalArticle

In situ biodistribution and residency of a topical anti-inflammatory using fluorescence lifetime imaging microscopy

Alex, A., Frey, S., Angelene, H., Neitzel, C. D., Li, J., Bower, A. J., Spillman, D. R., Marjanovic, M., Chaney, E. J., Medler, J. L., Lee, W., Vasist Johnson, L. S., Boppart, S. A. & Arp, Z., Dec 2018, In : British Journal of Dermatology. 179, 6, p. 1342-1350 9 p.

Research output: Contribution to journalArticle

Intraoperative optical coherence tomography of the human thyroid: Feasibility for surgical assessment

Erickson-Bhatt, S. J., Mesa, K. J., Marjanovic, M., Chaney, E. J., Ahmad, A., Huang, P. C., Liu, Z. G., Cunningham, K. & Boppart, S. A., May 2018, In : Translational Research. 195, p. 13-24 12 p.

Research output: Contribution to journalArticle

Intraoperative visualization of the tumor microenvironment and quantification of extracellular vesicles by label-free nonlinear imaging

Sun, Y., You, S., Tu, H., Spillman, D. R., Chaney, E. J., Marjanovic, M., Li, J., Barkalifa, R., Wang, J., Higham, A. M., Luckey, N. N., Cradock, K. A., Liu, Z. G. & Boppart, S. A., Dec 19 2018, In : Science Advances. 4, 12, eaau5603.

Research output: Contribution to journalArticle

Intravital imaging by simultaneous label-free autofluorescence-multiharmonic microscopy

You, S., Tu, H., Chaney, E. J., Sun, Y., Zhao, Y., Bower, A. J., Liu, Y. Z., Marjanovic, M., Sinha, S., Pu, Y. & Boppart, S. A., Dec 1 2018, In : Nature communications. 9, 1, 2125.

Research output: Contribution to journalArticle

Investigating the healing mechanisms of an angiogenesis-promoting topical treatment for diabetic wounds using multimodal microscopy

Li, J., Bower, A. J., Arp, Z., Olson, E. J., Holland, C., Chaney, E. J., Marjanovic, M., Pande, P., Alex, A. & Boppart, S. A., Mar 2018, In : Journal of Biophotonics. 11, 3, e201700195.

Research output: Contribution to journalArticle

In vivo detection of nanometer-scale structural changes of the human tympanic membrane in otitis media

Dsouza, R., Won, J., Monroy, G. L., Hill, M. C., Porter, R. G., Novak, M. A. & Boppart, S. A., Dec 1 2018, In : Scientific reports. 8, 1, 8777.

Research output: Contribution to journalArticle

Label-free optical imaging technologies for rapid translation and use during intraoperative surgical and tumor margin assessment

Boppart, S. A., Brown, J. Q., Farah, C. S., Kho, E., Marcu, L., Saunders, C. M. & Sterenborg, H. J. C. M., Feb 2018, In : Journal of biomedical optics. 23, 2, 021104.

Research output: Contribution to journalArticle

Magnetomotive Displacement of the Tympanic Membrane Using Magnetic Nanoparticles: Toward Enhancement of Sound Perception

Huang, P. C., Chaney, E. J., Shelton, R. L. & Boppart, S. A., Dec 2018, In : IEEE Transactions on Biomedical Engineering. 65, 12, p. 2837-2846 10 p., 8325518.

Research output: Contribution to journalArticle

Optical assessment of the in vivo tympanic membrane status using a handheld optical coherence tomography-based otoscope

Park, K., Cho, N. H., Jeon, M., Lee, S. H., Jang, J. H., Boppart, S. A., Jung, W. & Kim, J., Apr 3 2018, In : Acta Oto-Laryngologica. 138, 4, p. 367-374 8 p.

Research output: Contribution to journalArticle

Optical parametric amplification of gated confocal reflectance microscopy signals in scattering media

Sun, Y., Tu, H., You, S. & Boppart, S., Jan 1 2018, Frontiers in Optics, FIO 2018. OSA - The Optical Society, (Optics InfoBase Conference Papers; vol. Part F114-FIO 2018).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Pneumatic low-coherence interferometry otoscope to quantify tympanic membrane mobility and middle ear pressure

Won, J., Monroy, G. L., Huang, P. C., Dsouza, R., Hill, M. C., Novak, M. A., Porter, R. G., Chaney, E., Barkalifa, R. & Boppart, S. A., Feb 1 2018, In : Biomedical Optics Express. 9, 2, p. 397-409 13 p., #308905.

Research output: Contribution to journalArticle

Slide-free virtual histochemistry (Part I): Development via nonlinear optics

You, S., Sun, Y. I., Chaney, E. J., Zhao, Y., Chen, J., Boppart, S. A. & Tu, H., Nov 1 2018, In : Biomedical Optics Express. 9, 11, p. 5240-5252 13 p., #332416.

Research output: Contribution to journalArticle

Slide-free virtual histochemistry (Part II): Detection of field cancerization

You, S., Sun, Y., Chaney, E. J., Zhao, Y., Chen, J., Boppart, S. A. & Tu, H., Nov 1 2018, In : Biomedical Optics Express. 9, 11, p. 5253-5268 16 p., #332413.

Research output: Contribution to journalArticle

Structural OCT middle ear imaging correlated with functional wideband acoustic immittance measurements

Won, J., Monroy, G. L., Huang, P. C., Hill, M. C., Novak, M. A., Porter, R. G., Chaney, E., Barkalifa, R. & Boppart, S. A., Jan 1 2018, Clinical and Translational Biophotonics, TRANSLATIONAL 2018. OSA - The Optical Society, (Optics InfoBase Conference Papers; vol. Part F91-TRANSLATIONAL 2018).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Toward interstitial Magnetic hyperthermia dosimetry via magnetomotive optical coherence elastography

Huang, P. C., Spillman, D. R., Odintsov, B., Sobh, N. A. & Boppart, S. A., Jan 1 2018, Optical Tomography and Spectroscopy, OTS 2018. OSA - The Optical Society, (Optics InfoBase Conference Papers; vol. Part F90-OTS 2018).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Wavefront measurement using computational adaptive optics

South, F. A., Liu, Y. Z., Bower, A. J., Xu, Y., Carney, P. S. & Boppart, S. A., Mar 2018, In : Journal of the Optical Society of America A: Optics and Image Science, and Vision. 35, 3, p. 466-473 8 p.

Research output: Contribution to journalArticle

2017

Adaptive multiphoton imaging by high peak-power coherent fiber supercontinuum

Tu, H. & Boppart, S. A., Jan 1 2017, International Conference on Photonics and Imaging in Biology and Medicine, PIBM 2017. OSA - The Optical Society, (Optics InfoBase Conference Papers; vol. Part F70-PIBM 2017).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

A quantitative framework for the analysis of multimodal optical microscopy images

Bower, A. J., Chidester, B., Li, J., Zhao, Y., Marjanovic, M., Chaney, E. J., Do, M. N. & Boppart, S. A., Jan 1 2017, In : Quantitative Imaging in Medicine and Surgery. 7, 1, p. 24-37 14 p.

Research output: Contribution to journalArticle

Clinical translation of handheld optical coherence tomography: Practical considerations and recent advancements

Monroy, G. L., Won, J., Spillman, D. R., Dsouza, R. & Boppart, S. A., Dec 2017, In : Journal of biomedical optics. 22, 12, 121715.

Research output: Contribution to journalReview article

Coherent control of an opsin in living brain tissue

Paul, K., Sengupta, P., Ark, E. D., Tu, H., Zhao, Y. & Boppart, S. A., Nov 1 2017, In : Nature Physics. 13, 11, p. 1111-1116 6 p.

Research output: Contribution to journalArticle

Computational optical coherence tomography [invited]

Liu, Y. Z., South, F. A., Xu, Y., Scott Carney, P. & Boppart, S. A., Mar 1 2017, In : Biomedical Optics Express. 8, 3, p. 1549-1574 26 p.

Research output: Contribution to journalReview article