Scott K Silverman

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2017

DNA-catalyzed DNA cleavage by a radical pathway with well-defined products

Lee, Y., Klauser, P. C., Brandsen, B. M., Zhou, C., Li, X. & Silverman, S. K., Jan 11 2017, In : Journal of the American Chemical Society. 139, 1, p. 255-261 7 p.

Research output: Contribution to journalArticle

2016

Assessing histidine tags for recruiting deoxyribozymes to catalyze peptide and protein modification reactions

Chu, C. C. & Silverman, S. K., Jan 1 2016, In : Organic and Biomolecular Chemistry. 14, 20, p. 4697-4703 7 p.

Research output: Contribution to journalArticle

DNA-Catalyzed Amide Hydrolysis

Zhou, C., Avins, J. L., Klauser, P. C., Brandsen, B. M., Lee, Y. & Silverman, S. K., Mar 2 2016, In : Journal of the American Chemical Society. 138, 7, p. 2106-2109 4 p.

Research output: Contribution to journalArticle

DNA-catalyzed glycosylation using aryl glycoside donors

Hesser, A. R., Brandsen, B. M., Walsh, S. M., Wang, P. & Silverman, S. K., 2016, In : Chemical Communications. 52, 59, p. 9259-9262 4 p.

Research output: Contribution to journalArticle

DNA-Catalyzed Introduction of Azide at Tyrosine for Peptide Modification

Wang, P. & Silverman, S. K., Jan 1 2016, In : Angewandte Chemie - International Edition. 55, 34, p. 10052-10056 5 p.

Research output: Contribution to journalArticle

DNA Oligonucleotide 3′-Phosphorylation by a DNA Enzyme

Camden, A. J., Walsh, S. M., Suk, S. H. & Silverman, S. K., May 10 2016, In : Biochemistry. 55, 18, p. 2671-2676 6 p.

Research output: Contribution to journalArticle

2015

Identification of Sequence-Selective Tyrosine Kinase Deoxyribozymes

Walsh, S. M., Konecki, S. N. & Silverman, S. K., Dec 1 2015, In : Journal of Molecular Evolution. 81, 5-6, p. 218-224 7 p.

Research output: Contribution to journalArticle

Phosphoserine lyase deoxyribozymes: DNA-catalyzed formation of dehydroalanine residues in peptides

Chandrasekar, J., Wylder, A. C. & Silverman, S. K., Aug 5 2015, In : Journal of the American Chemical Society. 137, 30, p. 9575-9578 4 p.

Research output: Contribution to journalArticle

Pursuing DNA catalysts for protein modification

Silverman, S. K., May 19 2015, In : Accounts of chemical research. 48, 5, p. 1369-1379 11 p.

Research output: Contribution to journalArticle

Selective Aptamers for Detection of Estradiol and Ethynylestradiol in Natural Waters

Akki, S. U., Werth, C. J. & Silverman, S. K., Jul 16 2015, In : Environmental Science and Technology. 49, 16, p. 9905-9913 9 p.

Research output: Contribution to journalArticle

2014

A generalizable DNA-catalyzed approach to peptide-nucleic acid conjugation

Chu, C. C., Wong, O. Y. I. & Silverman, S. K., Sep 5 2014, In : Chembiochem : a European journal of chemical biology. 15, 13, p. 1905-1910 6 p.

Research output: Contribution to journalArticle

A modular tyrosine kinase deoxyribozyme with discrete aptamer and catalyst domains

Dokukin, V. & Silverman, S. K., Jul 22 2014, In : Chemical Communications. 50, 66, p. 9317-9320 4 p.

Research output: Contribution to journalArticle

DNA-catalyzed lysine side chain modification

Brandsen, B. M., Velez, T. E., Sachdeva, A., Ibrahim, N. A. & Silverman, S. K., Aug 18 2014, In : Angewandte Chemie - International Edition. 53, 34, p. 9045-9050 6 p.

Research output: Contribution to journalArticle

2013

Catalytic DNA with phosphatase activity

Chandrasekar, J. & Silverman, S. K., Apr 2 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 14, p. 5315-5320 6 p.

Research output: Contribution to journalArticle

DNA catalysis of a normally disfavored RNA hydrolysis reaction

Parker, D. J., Xiao, Y., Aguilar, J. M. & Silverman, S. K., Jun 12 2013, In : Journal of the American Chemical Society. 135, 23, p. 8472-8475 4 p.

Research output: Contribution to journalArticle

DNA catalysts with tyrosine kinase activity

Walsh, S. M., Sachdeva, A. & Silverman, S. K., Oct 21 2013, In : Journal of the American Chemical Society. 135, 40, p. 14928-14931 4 p.

Research output: Contribution to journalArticle

DNA-catalyzed hydrolysis of esters and aromatic amides

Brandsen, B. M., Hesser, A. R., Castner, M. A., Chandra, M. & Silverman, S. K., Oct 30 2013, In : Journal of the American Chemical Society. 135, 43, p. 16014-16017 4 p.

Research output: Contribution to journalArticle

2012

Covalent Tagging of Phosphorylated Peptides by Phosphate-Specific Deoxyribozymes

Sachdeva, A., Chandra, M., Chandrasekar, J. & Silverman, S. K., Mar 1 2012, In : ChemBioChem. 13, 5, p. 654-657 4 p.

Research output: Contribution to journalArticle

Establishing broad generality of DNA catalysts for site-specific hydrolysis of single-stranded DNA

Xiao, Y., Wehrmann, R. J., Ibrahim, N. A. & Silverman, S. K., Feb 1 2012, In : Nucleic acids research. 40, 4, p. 1778-1786 9 p.

Research output: Contribution to journalArticle

Lanthanide ions as required cofactors for DNA catalysts

Dokukin, V. & Silverman, S. K., May 1 2012, In : Chemical Science. 3, 5, p. 1707-1714 8 p.

Research output: Contribution to journalArticle

Systematic evaluation of the dependence of deoxyribozyme catalysis on random region length

Velez, T. E., Singh, J., Xiao, Y., Allen, E. C., Wong, O. Y., Chandra, M., Kwon, S. C. & Silverman, S. K., Dec 10 2012, In : ACS Combinatorial Science. 14, 12, p. 680-687 8 p.

Research output: Contribution to journalArticle

2011

DNA-catalyzed covalent modification of amino acid side chains in tethered and free peptide substrates

Wong, O. Y., Pradeepkumar, P. I. & Silverman, S. K., May 31 2011, In : Biochemistry. 50, 21, p. 4741-4749 9 p.

Research output: Contribution to journalArticle

DNA-catalyzed reductive amination

Wong, O. Y., Mulcrone, A. E. & Silverman, S. K., Dec 2 2011, In : Angewandte Chemie - International Edition. 50, 49, p. 11679-11684 6 p.

Research output: Contribution to journalArticle

Improved deoxyribozymes for synthesis of covalently branched DNA and RNA

Lee, C. S., Mui, T. P. & Silverman, S. K., Jan 17 2011, In : Nucleic acids research. 39, 1, p. 269-279 11 p.

Research output: Contribution to journalArticle

Merely two mutations switch a DNA-hydrolyzing deoxyribozyme from heterobimetallic (Zn2+/Mn2+) to monometallic (Zn2+-only) behavior

Xiao, Y., Allen, E. C. & Silverman, S. K., Jan 27 2011, In : Chemical Communications. 47, 6, p. 1749-1751 3 p.

Research output: Contribution to journalArticle

2010

DNA-catalyzed serine side chain reactivity and selectivity

Sachdeva, A. & Silverman, S. K., 2010, In : Chemical Communications. 46, 13, p. 2215-2217 3 p.

Research output: Contribution to journalArticle

Functional compromises among pH tolerance, site specificity, and sequence tolerance for a DNA-hydrolyzing deoxyribozyme

Xiao, Y., Chandra, M. & Silverman, S. K., Nov 9 2010, In : Biochemistry. 49, 44, p. 9630-9637 8 p.

Research output: Contribution to journalArticle

Multivector fluorescence analysis of the xpt guanine riboswitch aptamer domain and the conformational role of guanine

Brenner, M. D., Scanlan, M. S., Nahas, M. K., Ha, T. & Silverman, S. K., Mar 2 2010, In : Biochemistry. 49, 8, p. 1596-1605 10 p.

Research output: Contribution to journalArticle

2009

DNA-catalyzed sequence-specific hydrolysis of DNA

Chandra, M., Sachdeva, A. & Silverman, S. K., Oct 2009, In : Nature chemical biology. 5, 10, p. 718-720 3 p.

Research output: Contribution to journalArticle

Efficient control of group I intron ribozyme catalysis by DNA constraints

Zelin, E. & Silverman, S. K., 2009, In : Chemical Communications. 7, p. 767-769 3 p.

Research output: Contribution to journalArticle

Multimodal optical sensing and analyte specificity using single-walled carbon nanotubes

Heller, D. A., Jin, H., Martinez, B. M., Patel, D., Miller, B. M., Yeung, T. K., Jena, P. V., Höbartner, C., Ha, T., Silverman, S. K. & Strano, M. S., Feb 2009, In : Nature Nanotechnology. 4, 2, p. 114-120 7 p.

Research output: Contribution to journalArticle

Use of deoxyribozymes in RNA research.

Silverman, S. K. & Baum, D. A., 2009, In : Methods in enzymology. 469, p. 95-117 23 p.

Research output: Contribution to journalArticle

2008

Controlling the direction of site-selectivity and regioselectivity in RNA ligation by Zn2+-dependent deoxyribozymes that use 2′,3′-cyclic phosphate RNA substrates

Kost, D. M., Gerdt, J. P., Pradeepkumar, P. I. & Silverman, S. K., Nov 24 2008, In : Organic and Biomolecular Chemistry. 6, 23, p. 4391-4398 8 p.

Research output: Contribution to journalArticle

Convergent and general one-step DNA-catalyzed synthesis of multiply branched DNA

Mui, T. P. & Silverman, S. K., Dec 1 2008, In : Organic Letters. 10, 20, p. 4417-4420 4 p.

Research output: Contribution to journalArticle

DNA and RNA can be equally efficient catalysts for carbon-carbon bond formation

Chandra, M. & Silverman, S. K., Mar 12 2008, In : Journal of the American Chemical Society. 130, 10, p. 2936-2937 2 p.

Research output: Contribution to journalArticle

DNA-catalyzed formation of nucleopeptide linkages

Pradeepkumar, P. I., Höbartner, C., Baum, D. A. & Silverman, S. K., Feb 15 2008, In : Angewandte Chemie - International Edition. 47, 9, p. 1753-1757 5 p.

Research output: Contribution to journalArticle

Improvement of DNA adenylation using T4 DNA ligase with a template strand and a strategically mismatched acceptor strand

Patel, M. P., Baum, D. A. & Silverman, S. K., Apr 1 2008, In : Bioorganic Chemistry. 36, 2, p. 46-56 11 p.

Research output: Contribution to journalArticle

Selective stabilization of natively folded RNA structure by DNA constraints

Gerdt, J. P., Miduturu, C. V. & Silverman, S. K., Nov 12 2008, In : Journal of the American Chemical Society. 130, 45, p. 14920-14921 2 p.

Research output: Contribution to journalArticle

2007

Allosteric control of ribozyme catalysis by using DNA constraints

Zelin, E. & Silverman, S. K., Nov 5 2007, In : ChemBioChem. 8, 16, p. 1907-1911 5 p.

Research output: Contribution to journalArticle

A simple molecular model for thermophilic adaptation of functional nucleic acids

Blose, J. M., Silverman, S. K. & Bevilacqua, P. C., Apr 10 2007, In : Biochemistry. 46, 14, p. 4232-4240 9 p.

Research output: Contribution to journalArticle

Deoxyribozyme-catalyzed labeling of RNA

Baum, D. A. & Silverman, S. K., Jun 29 2007, In : Angewandte Chemie - International Edition. 46, 19, p. 3502-3504 3 p.

Research output: Contribution to journalArticle

Engineering a selective small-molecule substrate binding site into a deoxyribozyme

Höbartner, C. & Silverman, S. K., Oct 16 2007, In : Angewandte Chemie - International Edition. 46, 39, p. 7420-7424 5 p.

Research output: Contribution to journalArticle

Site-selective depurination by a periodate-dependent deoxyribozyme

Höbartner, C., Pradeepkumar, P. I. & Silverman, S. K., Jan 1 2007, In : Chemical Communications. 22, p. 2255-2257 3 p.

Research output: Contribution to journalArticle

Ty1 reverse transcriptase does not read through the proposed 2′,5′-branched retrotransposition intermediate in vitro

Pratico, E. D. & Silverman, S. K., Sep 2007, In : RNA. 13, 9, p. 1528-1536 9 p.

Research output: Contribution to journalArticle

2006

Adenosine is inherently favored as the branch-site RNA nucleotide in a structural context that resembles natural RNA splicing

Zelin, E., Wang, Y. & Silverman, S. K., Mar 7 2006, In : Biochemistry. 45, 9, p. 2767-2771 5 p.

Research output: Contribution to journalArticle

A general two-step strategy to synthesize lariat RNAs

Wang, Y. & Silverman, S. K., Feb 1 2006, In : RNA. 12, 2, p. 313-321 9 p.

Research output: Contribution to journalArticle

Efficient RNA 5′-adenylation by T4 DNA ligase to facilitate practical applications

Wang, Y. & Silverman, S. K., Jun 1 2006, In : RNA. 12, 6, p. 1142-1146 5 p.

Research output: Contribution to journalArticle

Experimental tests of two proofreading mechanisms for 5'-splice site selection.

Wang, Y. & Silverman, S. K., Jun 20 2006, In : ACS chemical biology. 1, 5, p. 316-324 9 p.

Research output: Contribution to journalArticle

Fluorescence of covalently attached pyrene as a general RNA folding probe

Smalley, M. K. & Silverman, S. K., Jan 1 2006, In : Nucleic acids research. 34, 1, p. 152-166 15 p.

Research output: Contribution to journalArticle