Scott K Silverman

1991 …2017

Research output per year

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Research Output

Article

Fluorescence of covalently attached pyrene as a general RNA folding probe

Smalley, M. K. & Silverman, S. K., Jan 1 2006, In : Nucleic acids research. 34, 1, p. 152-166 15 p.

Research output: Contribution to journalArticle

Functional compromises among pH tolerance, site specificity, and sequence tolerance for a DNA-hydrolyzing deoxyribozyme

Xiao, Y., Chandra, M. & Silverman, S. K., Nov 9 2010, In : Biochemistry. 49, 44, p. 9630-9637 8 p.

Research output: Contribution to journalArticle

General deoxyribozyme-catalyzed synthesis of native 3′-5′ RNA linkages

Purtha, W. E., Coppins, R. L., Smalley, M. K. & Silverman, S. K., Sep 28 2005, In : Journal of the American Chemical Society. 127, 38, p. 13124-13125 2 p.

Research output: Contribution to journalArticle

Identification of Sequence-Selective Tyrosine Kinase Deoxyribozymes

Walsh, S. M., Konecki, S. N. & Silverman, S. K., Dec 1 2015, In : Journal of Molecular Evolution. 81, 5-6, p. 218-224 7 p.

Research output: Contribution to journalArticle

Improved deoxyribozymes for synthesis of covalently branched DNA and RNA

Lee, C. S., Mui, T. P. & Silverman, S. K., Jan 17 2011, In : Nucleic acids research. 39, 1, p. 269-279 11 p.

Research output: Contribution to journalArticle

Improvement of DNA adenylation using T4 DNA ligase with a template strand and a strategically mismatched acceptor strand

Patel, M. P., Baum, D. A. & Silverman, S. K., Apr 1 2008, In : Bioorganic Chemistry. 36, 2, p. 46-56 11 p.

Research output: Contribution to journalArticle

In vitro evolution of an RNA-cleaving DNA enzyme into an RNA ligase switches the selectivity from 3′-5′ to 2′-5′

Flynn-Charlebois, A., Prior, T. K., Hoadley, K. A. & Silverman, S. K., May 7 2003, In : Journal of the American Chemical Society. 125, 18, p. 5346-5350 5 p.

Research output: Contribution to journalArticle

In vivo incorporation of unnatural amino acids into ion channels in Xenopus oocyte expression system

Nowak, M. W., Gallivan, J. P., Silverman, S. K., Labarca, C. G., Dougherty, D. A. & Lester, H. A., Jan 1 1998, In : Methods in enzymology. 293, p. 504-529 26 p.

Research output: Contribution to journalArticle

Lanthanide ions as required cofactors for DNA catalysts

Dokukin, V. & Silverman, S. K., May 1 2012, In : Chemical Science. 3, 5, p. 1707-1714 8 p.

Research output: Contribution to journalArticle

Merely two mutations switch a DNA-hydrolyzing deoxyribozyme from heterobimetallic (Zn2+/Mn2+) to monometallic (Zn 2+-only) behavior

Xiao, Y., Allen, E. C. & Silverman, S. K., Feb 14 2011, In : Chemical Communications. 47, 6, p. 1749-1751 3 p.

Research output: Contribution to journalArticle

Modulation of DNA constraints that control macromolecular folding

Miduturu, C. V. & Silverman, S. K., Mar 13 2006, In : Angewandte Chemie - International Edition. 45, 12, p. 1918-1921 4 p.

Research output: Contribution to journalArticle

Modulation of RNA tertiary folding by incorporation of caged nucleotides

Höbartner, C. & Silverman, S. K., Nov 11 2005, In : Angewandte Chemie - International Edition. 44, 44, p. 7305-7309 5 p.

Research output: Contribution to journalArticle

Multimodal optical sensing and analyte specificity using single-walled carbon nanotubes

Heller, D. A., Jin, H., Martinez, B. M., Patel, D., Miller, B. M., Yeung, T. K., Jena, P. V., Höbartner, C., Ha, T., Silverman, S. K. & Strano, M. S., Feb 2009, In : Nature Nanotechnology. 4, 2, p. 114-120 7 p.

Research output: Contribution to journalArticle

Multiple folding pathways for the P4-P6 RNA domain

Silverman, S. K., Deras, M. L., Woodson, S. A., Scaringe, S. A. & Cech, T. R., Oct 10 2000, In : Biochemistry. 39, 40, p. 12465-12475 11 p.

Research output: Contribution to journalArticle

Multivector fluorescence analysis of the xpt guanine riboswitch aptamer domain and the conformational role of guanine

Brenner, M. D., Scanlan, M. S., Nahas, M. K., Ha, T. & Silverman, S. K., Mar 2 2010, In : Biochemistry. 49, 8, p. 1596-1605 10 p.

Research output: Contribution to journalArticle

New Organic Polymers and Molecules with Very High Spin States

Dougherty, D. A., Jacobs, S. J., Silverman, S. K., Murray, M. M., Shultz, D. A., West, A. P. & Clites, J. A., Aug 1 1993, In : Molecular Crystals and Liquid Crystals Science and Technology. Section A. Molecular Crystals and Liquid Crystals. 232, 1, p. 289-304 16 p.

Research output: Contribution to journalArticle

Nicotinic receptor binding site probed with unnatural amino acid incorporation in intact cells

Nowak, M. W., Kearney, P. C., Sampson, J. R., Saks, M. E., Labarca, C. G., Silverman, S. K., Zhong, W., Thorson, J., Abelson, J. N., Davidson, N., Schultz, P. G., Dougherty, D. A. & Lester, H. A., Jan 1 1995, In : Science. 268, 5209, p. 439-442 4 p.

Research output: Contribution to journalArticle

Optimization and generality of a small deoxyribozyme that ligates RNA

Ricca, B. L., Wolf, A. C. & Silverman, S. K., Jul 25 2003, In : Journal of Molecular Biology. 330, 5, p. 1015-1025 11 p.

Research output: Contribution to journalArticle

Phosphoserine lyase deoxyribozymes: DNA-catalyzed formation of dehydroalanine residues in peptides

Chandrasekar, J., Wylder, A. C. & Silverman, S. K., Aug 5 2015, In : Journal of the American Chemical Society. 137, 30, p. 9575-9578 4 p.

Research output: Contribution to journalArticle

Practical and general synthesis of 5′-adenylated RNA (5′-AppRNA)

Silverman, S. K., Apr 1 2004, In : RNA. 10, 4, p. 731-746 16 p.

Research output: Contribution to journalArticle

Pursuing DNA catalysts for protein modification

Silverman, S. K., May 19 2015, In : Accounts of chemical research. 48, 5, p. 1369-1379 11 p.

Research output: Contribution to journalArticle

Quantifying the energetic interplay of RNA tertiary and secondary structure interactions

Silverman, S. K., Zheng, M., Wu, M., Tinoco, I. & Cech, T. R., Dec 1 1999, In : RNA. 5, 12, p. 1665-1674 10 p.

Research output: Contribution to journalArticle

Rational modification of a selection strategy leads to deoxyribozymes that create native 3′-5′ RNA linkages

Coppins, R. L. & Silverman, S. K., Dec 22 2004, In : Journal of the American Chemical Society. 126, 50, p. 16426-16432 7 p.

Research output: Contribution to journalArticle

Reaction of C60 with Dimethyldioxirane—Formation of an Epoxide and a 1,3‐Dioxolane Derivative

Elemes, Y., Silverman, S. K., Sheu, C., Kao, M., Foote, C. S., Alvarez, M. M. & Whetten, R. L., Mar 1992, In : Angewandte Chemie International Edition in English. 31, 3, p. 351-353 3 p.

Research output: Contribution to journalArticle

RNA tertiary folding monitored by fluorescence of covalently attached pyrene

Silverman, S. K. & Cech, T. R., Oct 26 1999, In : Biochemistry. 38, 43, p. 14224-14237 14 p.

Research output: Contribution to journalArticle

Selective Aptamers for Detection of Estradiol and Ethynylestradiol in Natural Waters

Akki, S. U., Werth, C. J. & Silverman, S. K., Jul 16 2015, In : Environmental Science and Technology. 49, 16, p. 9905-9913 9 p.

Research output: Contribution to journalArticle

Selective stabilization of natively folded RNA structure by DNA constraints

Gerdt, J. P., Miduturu, C. V. & Silverman, S. K., Nov 12 2008, In : Journal of the American Chemical Society. 130, 45, p. 14920-14921 2 p.

Research output: Contribution to journalArticle

Site-selective depurination by a periodate-dependent deoxyribozyme

Höbartner, C., Pradeepkumar, P. I. & Silverman, S. K., Jun 6 2007, In : Chemical Communications. 22, p. 2255-2257 3 p.

Research output: Contribution to journalArticle

Structure-function correlations derived from faster variants of a RNA ligase deoxyribozyme

Prior, T. K., Semlow, D. R., Flynn-Charlebois, A., Rashid, I. & Silverman, S. K., Jul 14 2004, In : Nucleic acids research. 32, 3, p. 1075-1082 8 p.

Research output: Contribution to journalArticle

Subunit stoichiometry of a heteromultimeric G protein-coupled inward- rectifier K+ channel

Silverman, S. K., Lester, H. A. & Dougherty, D. A., Dec 14 1996, In : Journal of Biological Chemistry. 271, 48, p. 30524-30528 5 p.

Research output: Contribution to journalArticle

Synthesis and application of a 5′-aldehyde phosphoramidite for covalent attachment of DNA to biomolecules

Miduturu, C. V. & Silverman, S. K., Jul 21 2006, In : Journal of Organic Chemistry. 71, 15, p. 5774-5777 4 p.

Research output: Contribution to journalArticle

Synthesis of amine- and thiol-modified nucleoside phosphoramidites for site-specific introduction of biophysical probes into RNA

Jin, S., Miduturu, C. V., McKinney, D. C. & Silverman, S. K., May 27 2005, In : Journal of Organic Chemistry. 70, 11, p. 4284-4299 16 p.

Research output: Contribution to journalArticle

Systematic evaluation of the dependence of deoxyribozyme catalysis on random region length

Velez, T. E., Singh, J., Xiao, Y., Allen, E. C., Wong, O. Y., Chandra, M., Kwon, S. C. & Silverman, S. K., Dec 10 2012, In : ACS Combinatorial Science. 14, 12, p. 680-687 8 p.

Research output: Contribution to journalArticle

The GAAA tetraloop-receptor interaction contributes differentially to folding thermodynamics and kinetics for the P4-P6 RNA domain

Young, B. T. & Silverman, S. K., Oct 15 2002, In : Biochemistry. 41, 41, p. 12271-12276 6 p.

Research output: Contribution to journalArticle

Ty1 reverse transcriptase does not read through the proposed 2′,5′-branched retrotransposition intermediate in vitro

Pratico, E. D. & Silverman, S. K., Sep 1 2007, In : RNA. 13, 9, p. 1528-1536 9 p.

Research output: Contribution to journalArticle

Use of deoxyribozymes in RNA research.

Silverman, S. K. & Baum, D. A., 2009, In : Methods in enzymology. 469, p. 95-117 23 p.

Research output: Contribution to journalArticle

Zn2+-dependent deoxyribozymes that form natural and unnatural RNA linkages

Hoadley, K. A., Purtha, W. E., Wolf, A. C., Flynn-Charlebois, A. & Silverman, S. K., Jun 28 2005, In : Biochemistry. 44, 25, p. 9217-9231 15 p.

Research output: Contribution to journalArticle

Book

Nucleic acid switches and sensors

Silverman, S. K., 2006, New, York, N, Y: Springer Science+Business Media.

Research output: Book/ReportBook

Review article

Breaking Up Is Easy to Do (If You're a DNA Enzyme that Cleaves RNA)

Silverman, S. K., Jan 2004, In : Chemistry and Biology. 11, 1, p. 7-8 2 p.

Research output: Contribution to journalReview article

Catalytic DNA: Scope, Applications, and Biochemistry of Deoxyribozymes

Silverman, S. K., Jul 1 2016, In : Trends in Biochemical Sciences. 41, 7, p. 595-609 15 p.

Research output: Contribution to journalReview article

Catalytic DNA (deoxyribozymes) for synthetic applications-current abilities and future prospects

Silverman, S. K., Jul 30 2008, In : Chemical Communications. 30, p. 3467-3485 19 p.

Research output: Contribution to journalReview article

Control of macromolecular structure and function using covalently attached double-stranded DNA constraints

Silverman, S. K., Jan 1 2007, In : Molecular BioSystems. 3, 1, p. 24-29 6 p.

Research output: Contribution to journalReview article

Deoxyribozymes: Useful DNA catalysts in vitro and in vivo

Baum, D. A. & Silverman, S. K., Jul 1 2008, In : Cellular and Molecular Life Sciences. 65, 14, p. 2156-2174 19 p.

Research output: Contribution to journalReview article

Deoxyribozymes: DNA catalysts for bioorganic chemistry

Silverman, S. K., Oct 7 2004, In : Organic and Biomolecular Chemistry. 2, 19, p. 2701-2706 6 p.

Research output: Contribution to journalReview article