Scott K Silverman

1991 …2017

Research output per year

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Research Output

2006

Nucleic acid switches and sensors

Silverman, S. K., 2006, New, York, N, Y: Springer Science+Business Media.

Research output: Book/ReportBook

Synthesis and application of a 5′-aldehyde phosphoramidite for covalent attachment of DNA to biomolecules

Miduturu, C. V. & Silverman, S. K., Jul 21 2006, In : Journal of Organic Chemistry. 71, 15, p. 5774-5777 4 p.

Research output: Contribution to journalArticle

2007

Allosteric control of ribozyme catalysis by using DNA constraints

Zelin, E. & Silverman, S. K., Nov 5 2007, In : ChemBioChem. 8, 16, p. 1907-1911 5 p.

Research output: Contribution to journalArticle

A simple molecular model for thermophilic adaptation of functional nucleic acids

Blose, J. M., Silverman, S. K. & Bevilacqua, P. C., Apr 10 2007, In : Biochemistry. 46, 14, p. 4232-4240 9 p.

Research output: Contribution to journalArticle

Control of macromolecular structure and function using covalently attached double-stranded DNA constraints

Silverman, S. K., Jan 1 2007, In : Molecular BioSystems. 3, 1, p. 24-29 6 p.

Research output: Contribution to journalReview article

Deoxyribozyme-catalyzed labeling of RNA

Baum, D. A. & Silverman, S. K., Jun 29 2007, In : Angewandte Chemie - International Edition. 46, 19, p. 3502-3504 3 p.

Research output: Contribution to journalArticle

Engineering a selective small-molecule substrate binding site into a deoxyribozyme

Höbartner, C. & Silverman, S. K., Oct 16 2007, In : Angewandte Chemie - International Edition. 46, 39, p. 7420-7424 5 p.

Research output: Contribution to journalArticle

Review: Recent advances in DNA catalysis

Höbartner, C. & Silverman, S. K., Dec 5 2007, In : Biopolymers. 87, 5-6, p. 279-292 14 p.

Research output: Contribution to journalReview article

Site-selective depurination by a periodate-dependent deoxyribozyme

Höbartner, C., Pradeepkumar, P. I. & Silverman, S. K., Jun 6 2007, In : Chemical Communications. 22, p. 2255-2257 3 p.

Research output: Contribution to journalArticle

Ty1 reverse transcriptase does not read through the proposed 2′,5′-branched retrotransposition intermediate in vitro

Pratico, E. D. & Silverman, S. K., Sep 1 2007, In : RNA. 13, 9, p. 1528-1536 9 p.

Research output: Contribution to journalArticle

2008

A Forced March across an RNA Folding Landscape

Silverman, S. K., Mar 21 2008, In : Chemistry and Biology. 15, 3, p. 211-213 3 p.

Research output: Contribution to journalShort survey

Catalytic DNA (deoxyribozymes) for synthetic applications-current abilities and future prospects

Silverman, S. K., Jul 30 2008, In : Chemical Communications. 30, p. 3467-3485 19 p.

Research output: Contribution to journalReview article

Controlling the direction of site-selectivity and regioselectivity in RNA ligation by Zn2+-dependent deoxyribozymes that use 2′,3′-cyclic phosphate RNA substrates

Kost, D. M., Gerdt, J. P., Pradeepkumar, P. I. & Silverman, S. K., Nov 24 2008, In : Organic and Biomolecular Chemistry. 6, 23, p. 4391-4398 8 p.

Research output: Contribution to journalArticle

Convergent and general one-step DNA-catalyzed synthesis of multiply branched DNA

Mui, T. P. & Silverman, S. K., Dec 1 2008, In : Organic Letters. 10, 20, p. 4417-4420 4 p.

Research output: Contribution to journalArticle

Deoxyribozymes: Useful DNA catalysts in vitro and in vivo

Baum, D. A. & Silverman, S. K., Jul 1 2008, In : Cellular and Molecular Life Sciences. 65, 14, p. 2156-2174 19 p.

Research output: Contribution to journalReview article

DNA and RNA can be equally efficient catalysts for carbon-carbon bond formation

Chandra, M. & Silverman, S. K., Mar 12 2008, In : Journal of the American Chemical Society. 130, 10, p. 2936-2937 2 p.

Research output: Contribution to journalArticle

DNA-catalyzed formation of nucleopeptide linkages

Pradeepkumar, P. I., Höbartner, C., Baum, D. A. & Silverman, S. K., Feb 15 2008, In : Angewandte Chemie - International Edition. 47, 9, p. 1753-1757 5 p.

Research output: Contribution to journalArticle

Improvement of DNA adenylation using T4 DNA ligase with a template strand and a strategically mismatched acceptor strand

Patel, M. P., Baum, D. A. & Silverman, S. K., Apr 1 2008, In : Bioorganic Chemistry. 36, 2, p. 46-56 11 p.

Research output: Contribution to journalArticle

Selective stabilization of natively folded RNA structure by DNA constraints

Gerdt, J. P., Miduturu, C. V. & Silverman, S. K., Nov 12 2008, In : Journal of the American Chemical Society. 130, 45, p. 14920-14921 2 p.

Research output: Contribution to journalArticle

2009

Deoxyribozymes: selection design and serendipity in the development of DNA catalysts.

Silverman, S. K., Oct 20 2009, In : Accounts of chemical research. 42, 10, p. 1521-1531 11 p.

Research output: Contribution to journalReview article

DNA-catalyzed sequence-specific hydrolysis of DNA

Chandra, M., Sachdeva, A. & Silverman, S. K., Oct 2009, In : Nature chemical biology. 5, 10, p. 718-720 3 p.

Research output: Contribution to journalArticle

Efficient control of group I intron ribozyme catalysis by DNA constraints

Zelin, E. & Silverman, S. K., Mar 30 2009, In : Chemical Communications. 7, p. 767-769 3 p.

Research output: Contribution to journalArticle

Multimodal optical sensing and analyte specificity using single-walled carbon nanotubes

Heller, D. A., Jin, H., Martinez, B. M., Patel, D., Miller, B. M., Yeung, T. K., Jena, P. V., Höbartner, C., Ha, T., Silverman, S. K. & Strano, M. S., Feb 2009, In : Nature Nanotechnology. 4, 2, p. 114-120 7 p.

Research output: Contribution to journalArticle

Use of deoxyribozymes in RNA research.

Silverman, S. K. & Baum, D. A., 2009, In : Methods in enzymology. 469, p. 95-117 23 p.

Research output: Contribution to journalArticle

2010

DNA as a versatile chemical component for catalysis, encoding, and stereocontrol

Silverman, S. K., Sep 24 2010, In : Angewandte Chemie - International Edition. 49, 40, p. 7180-7201 22 p.

Research output: Contribution to journalReview article

DNA-catalyzed serine side chain reactivity and selectivity

Sachdeva, A. & Silverman, S. K., Mar 25 2010, In : Chemical Communications. 46, 13, p. 2215-2217 3 p.

Research output: Contribution to journalArticle

Functional compromises among pH tolerance, site specificity, and sequence tolerance for a DNA-hydrolyzing deoxyribozyme

Xiao, Y., Chandra, M. & Silverman, S. K., Nov 9 2010, In : Biochemistry. 49, 44, p. 9630-9637 8 p.

Research output: Contribution to journalArticle

Multivector fluorescence analysis of the xpt guanine riboswitch aptamer domain and the conformational role of guanine

Brenner, M. D., Scanlan, M. S., Nahas, M. K., Ha, T. & Silverman, S. K., Mar 2 2010, In : Biochemistry. 49, 8, p. 1596-1605 10 p.

Research output: Contribution to journalArticle

2011

DNA-catalyzed covalent modification of amino acid side chains in tethered and free peptide substrates

Wong, O. Y., Pradeepkumar, P. I. & Silverman, S. K., May 31 2011, In : Biochemistry. 50, 21, p. 4741-4749 9 p.

Research output: Contribution to journalArticle

DNA-catalyzed reductive amination

Wong, O. Y., Mulcrone, A. E. & Silverman, S. K., Dec 2 2011, In : Angewandte Chemie - International Edition. 50, 49, p. 11679-11684 6 p.

Research output: Contribution to journalArticle

Improved deoxyribozymes for synthesis of covalently branched DNA and RNA

Lee, C. S., Mui, T. P. & Silverman, S. K., Jan 17 2011, In : Nucleic acids research. 39, 1, p. 269-279 11 p.

Research output: Contribution to journalArticle

Merely two mutations switch a DNA-hydrolyzing deoxyribozyme from heterobimetallic (Zn2+/Mn2+) to monometallic (Zn 2+-only) behavior

Xiao, Y., Allen, E. C. & Silverman, S. K., Feb 14 2011, In : Chemical Communications. 47, 6, p. 1749-1751 3 p.

Research output: Contribution to journalArticle

2012

Covalent Tagging of Phosphorylated Peptides by Phosphate-Specific Deoxyribozymes

Sachdeva, A., Chandra, M., Chandrasekar, J. & Silverman, S. K., Mar 1 2012, In : ChemBioChem. 13, 5, p. 654-657 4 p.

Research output: Contribution to journalArticle

Establishing broad generality of DNA catalysts for site-specific hydrolysis of single-stranded DNA

Xiao, Y., Wehrmann, R. J., Ibrahim, N. A. & Silverman, S. K., Feb 1 2012, In : Nucleic acids research. 40, 4, p. 1778-1786 9 p.

Research output: Contribution to journalArticle

Lanthanide ions as required cofactors for DNA catalysts

Dokukin, V. & Silverman, S. K., May 1 2012, In : Chemical Science. 3, 5, p. 1707-1714 8 p.

Research output: Contribution to journalArticle

Selective functionalization: Shields for small molecules

Silverman, S. K., Oct 1 2012, In : Nature Chemistry. 4, 10, p. 774-775 2 p.

Research output: Contribution to journalShort survey

Systematic evaluation of the dependence of deoxyribozyme catalysis on random region length

Velez, T. E., Singh, J., Xiao, Y., Allen, E. C., Wong, O. Y., Chandra, M., Kwon, S. C. & Silverman, S. K., Dec 10 2012, In : ACS Combinatorial Science. 14, 12, p. 680-687 8 p.

Research output: Contribution to journalArticle

2013

Catalytic DNA with phosphatase activity

Chandrasekar, J. & Silverman, S. K., Apr 2 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 14, p. 5315-5320 6 p.

Research output: Contribution to journalArticle

DNA catalysis of a normally disfavored RNA hydrolysis reaction

Parker, D. J., Xiao, Y., Aguilar, J. M. & Silverman, S. K., Jun 12 2013, In : Journal of the American Chemical Society. 135, 23, p. 8472-8475 4 p.

Research output: Contribution to journalArticle

DNA catalysts with tyrosine kinase activity

Walsh, S. M., Sachdeva, A. & Silverman, S. K., Oct 21 2013, In : Journal of the American Chemical Society. 135, 40, p. 14928-14931 4 p.

Research output: Contribution to journalArticle

DNA-catalyzed hydrolysis of esters and aromatic amides

Brandsen, B. M., Hesser, A. R., Castner, M. A., Chandra, M. & Silverman, S. K., Oct 30 2013, In : Journal of the American Chemical Society. 135, 43, p. 16014-16017 4 p.

Research output: Contribution to journalArticle

2014

A generalizable DNA-catalyzed approach to peptide-nucleic acid conjugation

Chu, C. C., Wong, O. Y. I. & Silverman, S. K., Sep 5 2014, In : Chembiochem : a European journal of chemical biology. 15, 13, p. 1905-1910 6 p.

Research output: Contribution to journalArticle

A modular tyrosine kinase deoxyribozyme with discrete aptamer and catalyst domains

Dokukin, V. & Silverman, S. K., Aug 25 2014, In : Chemical Communications. 50, 66, p. 9317-9320 4 p.

Research output: Contribution to journalArticle

DNA-catalyzed lysine side chain modification

Brandsen, B. M., Velez, T. E., Sachdeva, A., Ibrahim, N. A. & Silverman, S. K., Aug 18 2014, In : Angewandte Chemie - International Edition. 53, 34, p. 9045-9050 6 p.

Research output: Contribution to journalArticle

2015

Identification of Sequence-Selective Tyrosine Kinase Deoxyribozymes

Walsh, S. M., Konecki, S. N. & Silverman, S. K., Dec 1 2015, In : Journal of Molecular Evolution. 81, 5-6, p. 218-224 7 p.

Research output: Contribution to journalArticle

Phosphoserine lyase deoxyribozymes: DNA-catalyzed formation of dehydroalanine residues in peptides

Chandrasekar, J., Wylder, A. C. & Silverman, S. K., Aug 5 2015, In : Journal of the American Chemical Society. 137, 30, p. 9575-9578 4 p.

Research output: Contribution to journalArticle

Pursuing DNA catalysts for protein modification

Silverman, S. K., May 19 2015, In : Accounts of chemical research. 48, 5, p. 1369-1379 11 p.

Research output: Contribution to journalArticle

Selective Aptamers for Detection of Estradiol and Ethynylestradiol in Natural Waters

Akki, S. U., Werth, C. J. & Silverman, S. K., Jul 16 2015, In : Environmental Science and Technology. 49, 16, p. 9905-9913 9 p.

Research output: Contribution to journalArticle