Scott K Silverman

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Research Output

Article

Adenosine is inherently favored as the branch-site RNA nucleotide in a structural context that resembles natural RNA splicing

Zelin, E., Wang, Y. & Silverman, S. K., Mar 7 2006, In : Biochemistry. 45, 9, p. 2767-2771 5 p.

Research output: Contribution to journalArticle

A deoxyribozyme that synthesizes 2′,5′-branched RNA with any branch-site nucleotide

Pratico, E. D., Wang, Y. & Silverman, S. K., 2005, In : Nucleic acids research. 33, 11, p. 3503-3512 10 p.

Research output: Contribution to journalArticle

A DNA enzyme that mimics the first step of RNA splicing

Coppins, R. L. & Silverman, S. K., Mar 1 2004, In : Nature Structural and Molecular Biology. 11, 3, p. 270-274 5 p.

Research output: Contribution to journalArticle

A generalizable DNA-catalyzed approach to peptide-nucleic acid conjugation

Chu, C. C., Wong, O. Y. I. & Silverman, S. K., Sep 5 2014, In : Chembiochem : a European journal of chemical biology. 15, 13, p. 1905-1910 6 p.

Research output: Contribution to journalArticle

A general two-step strategy to synthesize lariat RNAs

Wang, Y. & Silverman, S. K., Feb 2006, In : RNA. 12, 2, p. 313-321 9 p.

Research output: Contribution to journalArticle

Allosteric control of ribozyme catalysis by using DNA constraints

Zelin, E. & Silverman, S. K., Nov 5 2007, In : ChemBioChem. 8, 16, p. 1907-1911 5 p.

Research output: Contribution to journalArticle

A modular tyrosine kinase deoxyribozyme with discrete aptamer and catalyst domains

Dokukin, V. & Silverman, S. K., Jul 22 2014, In : Chemical Communications. 50, 66, p. 9317-9320 4 p.

Research output: Contribution to journalArticle

An early transition state for folding of the P4-P6 RNA domain

Silverman, S. K. & Cech, T. R., Feb 2001, In : RNA. 7, 2, p. 161-166 6 p.

Research output: Contribution to journalArticle

A regenerative link in the ionic fluxes through the weaver potassium channel underlies the pathophysiology of the mutation

Silverman, S. K., Kofuji, P., Dougherty, D. A., Davidson, N. & Lester, H. A., Dec 24 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 26, p. 15429-15434 6 p.

Research output: Contribution to journalArticle

A simple molecular model for thermophilic adaptation of functional nucleic acids

Blose, J. M., Silverman, S. K. & Bevilacqua, P. C., Apr 10 2007, In : Biochemistry. 46, 14, p. 4232-4240 9 p.

Research output: Contribution to journalArticle

Asymmetrical contributions of subunit pore regions to ion selectivity in an inward rectifier K+ channel

Silverman, S. K., Lester, H. A. & Dougherty, D. A., Sep 1998, In : Biophysical journal. 75, 3, p. 1330-1339 10 p.

Research output: Contribution to journalArticle

Catalytic DNA with phosphatase activity

Chandrasekar, J. & Silverman, S. K., Apr 2 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 14, p. 5315-5320 6 p.

Research output: Contribution to journalArticle

Characterization of Deoxyribozymes That Synthesize Branched RNA

Wang, Y. & Silverman, S. K., Dec 30 2003, In : Biochemistry. 42, 51, p. 15252-15263 12 p.

Research output: Contribution to journalArticle

Conformational effects on high-spin organic molecules

Silverman, S. K. & Dougherty, D. A., 1993, In : Journal of physical chemistry. 97, 50, p. 13273-13283 11 p.

Research output: Contribution to journalArticle

Controlling the direction of site-selectivity and regioselectivity in RNA ligation by Zn2+-dependent deoxyribozymes that use 2′,3′-cyclic phosphate RNA substrates

Kost, D. M., Gerdt, J. P., Pradeepkumar, P. I. & Silverman, S. K., Nov 24 2008, In : Organic and Biomolecular Chemistry. 6, 23, p. 4391-4398 8 p.

Research output: Contribution to journalArticle

Convergent and general one-step DNA-catalyzed synthesis of multiply branched DNA

Mui, T. P. & Silverman, S. K., Dec 1 2008, In : Organic Letters. 10, 20, p. 4417-4420 4 p.

Research output: Contribution to journalArticle

Covalent Tagging of Phosphorylated Peptides by Phosphate-Specific Deoxyribozymes

Sachdeva, A., Chandra, M., Chandrasekar, J. & Silverman, S. K., Mar 2012, In : ChemBioChem. 13, 5, p. 654-657 4 p.

Research output: Contribution to journalArticle

Deoxyribozyme-catalyzed labeling of RNA

Baum, D. A. & Silverman, S. K., 2007, In : Angewandte Chemie - International Edition. 46, 19, p. 3502-3504 3 p.

Research output: Contribution to journalArticle

Deoxyribozymes that synthesize branched and lariat RNA

Wang, Y. & Silverman, S. K., Jun 11 2003, In : Journal of the American Chemical Society. 125, 23, p. 6880-6881 2 p.

Research output: Contribution to journalArticle

Deoxyribozymes with 2′-5′ RNA ligase activity

Flynn-Charlebois, A., Wang, Y., Prior, T. K., Rashid, I., Hoadley, K. A., Coppins, R. L., Wolf, A. C. & Silverman, S. K., Mar 5 2003, In : Journal of the American Chemical Society. 125, 9, p. 2444-2454 11 p.

Research output: Contribution to journalArticle

Directing the outcome of deoxyribozyme selections to favor native 3′-5′ RNA ligation

Wang, Y. & Silverman, S. K., Mar 1 2005, In : Biochemistry. 44, 8, p. 3017-3023 7 p.

Research output: Contribution to journalArticle

DNA and RNA can be equally efficient catalysts for carbon-carbon bond formation

Chandra, M. & Silverman, S. K., Mar 12 2008, In : Journal of the American Chemical Society. 130, 10, p. 2936-2937 2 p.

Research output: Contribution to journalArticle

DNA catalysis of a normally disfavored RNA hydrolysis reaction

Parker, D. J., Xiao, Y., Aguilar, J. M. & Silverman, S. K., Jun 12 2013, In : Journal of the American Chemical Society. 135, 23, p. 8472-8475 4 p.

Research output: Contribution to journalArticle

DNA catalysts with tyrosine kinase activity

Walsh, S. M., Sachdeva, A. & Silverman, S. K., 2013, In : Journal of the American Chemical Society. 135, 40, p. 14928-14931 4 p.

Research output: Contribution to journalArticle

DNA-Catalyzed Amide Hydrolysis

Zhou, C., Avins, J. L., Klauser, P. C., Brandsen, B. M., Lee, Y. & Silverman, S. K., Mar 2 2016, In : Journal of the American Chemical Society. 138, 7, p. 2106-2109 4 p.

Research output: Contribution to journalArticle

DNA-catalyzed covalent modification of amino acid side chains in tethered and free peptide substrates

Wong, O. Y., Pradeepkumar, P. I. & Silverman, S. K., May 31 2011, In : Biochemistry. 50, 21, p. 4741-4749 9 p.

Research output: Contribution to journalArticle

DNA-catalyzed DNA cleavage by a radical pathway with well-defined products

Lee, Y., Klauser, P. C., Brandsen, B. M., Zhou, C., Li, X. & Silverman, S. K., Jan 11 2017, In : Journal of the American Chemical Society. 139, 1, p. 255-261 7 p.

Research output: Contribution to journalArticle

DNA-catalyzed formation of nucleopeptide linkages

Pradeepkumar, P. I., Höbartner, C., Baum, D. A. & Silverman, S. K., Feb 15 2008, In : Angewandte Chemie - International Edition. 47, 9, p. 1753-1757 5 p.

Research output: Contribution to journalArticle

DNA-catalyzed glycosylation using aryl glycoside donors

Hesser, A. R., Brandsen, B. M., Walsh, S. M., Wang, P. & Silverman, S. K., 2016, In : Chemical Communications. 52, 59, p. 9259-9262 4 p.

Research output: Contribution to journalArticle

DNA-catalyzed hydrolysis of esters and aromatic amides

Brandsen, B. M., Hesser, A. R., Castner, M. A., Chandra, M. & Silverman, S. K., Oct 30 2013, In : Journal of the American Chemical Society. 135, 43, p. 16014-16017 4 p.

Research output: Contribution to journalArticle

DNA-Catalyzed Introduction of Azide at Tyrosine for Peptide Modification

Wang, P. & Silverman, S. K., Jan 1 2016, In : Angewandte Chemie - International Edition. 55, 34, p. 10052-10056 5 p.

Research output: Contribution to journalArticle

DNA-catalyzed lysine side chain modification

Brandsen, B. M., Velez, T. E., Sachdeva, A., Ibrahim, N. A. & Silverman, S. K., Aug 18 2014, In : Angewandte Chemie - International Edition. 53, 34, p. 9045-9050 6 p.

Research output: Contribution to journalArticle

DNA-catalyzed reductive amination

Wong, O. Y., Mulcrone, A. E. & Silverman, S. K., Dec 2 2011, In : Angewandte Chemie - International Edition. 50, 49, p. 11679-11684 6 p.

Research output: Contribution to journalArticle

DNA-catalyzed sequence-specific hydrolysis of DNA

Chandra, M., Sachdeva, A. & Silverman, S. K., Oct 2009, In : Nature chemical biology. 5, 10, p. 718-720 3 p.

Research output: Contribution to journalArticle

DNA-catalyzed serine side chain reactivity and selectivity

Sachdeva, A. & Silverman, S. K., 2010, In : Chemical Communications. 46, 13, p. 2215-2217 3 p.

Research output: Contribution to journalArticle

DNA constraints allow rational control of macromolecular conformation

Miduturu, C. V. & Silverman, S. K., Jul 27 2005, In : Journal of the American Chemical Society. 127, 29, p. 10144-10145 2 p.

Research output: Contribution to journalArticle

DNA Oligonucleotide 3′-Phosphorylation by a DNA Enzyme

Camden, A. J., Walsh, S. M., Suk, S. H. & Silverman, S. K., May 10 2016, In : Biochemistry. 55, 18, p. 2671-2676 6 p.

Research output: Contribution to journalArticle

Dose-response relations for unnatural amino acids at the agonist binding site of the nicotinic acetylcholine receptor: Tests with novel side chains and with several agonists

Kearney, P. C., Nowak, M. W., Zhong, W., Silverman, S. K., Lester, H. A. & Dougherty, D. A., Nov 1996, In : Molecular Pharmacology. 50, 5, p. 1401-1412 12 p.

Research output: Contribution to journalArticle

Efficient control of group I intron ribozyme catalysis by DNA constraints

Zelin, E. & Silverman, S. K., 2009, In : Chemical Communications. 7, p. 767-769 3 p.

Research output: Contribution to journalArticle

Efficient one-step synthesis of biologically related lariat RNAs by a deoxyribozyme

Wang, Y. & Silverman, S. K., Sep 4 2005, In : Angewandte Chemie - International Edition. 44, 36, p. 5863-5866 4 p.

Research output: Contribution to journalArticle

Efficient RNA 5′-adenylation by T4 DNA ligase to facilitate practical applications

Wang, Y. & Silverman, S. K., Jun 2006, In : RNA. 12, 6, p. 1142-1146 5 p.

Research output: Contribution to journalArticle

Energetics and cooperativity of tertiary hydrogen bonds in RNA structure

Silverman, S. K. & Cech, T. R., Jul 6 1999, In : Biochemistry. 38, 27, p. 8691-8702 12 p.

Research output: Contribution to journalArticle

Engineering a selective small-molecule substrate binding site into a deoxyribozyme

Höbartner, C. & Silverman, S. K., Oct 16 2007, In : Angewandte Chemie - International Edition. 46, 39, p. 7420-7424 5 p.

Research output: Contribution to journalArticle

Establishing broad generality of DNA catalysts for site-specific hydrolysis of single-stranded DNA

Xiao, Y., Wehrmann, R. J., Ibrahim, N. A. & Silverman, S. K., Feb 1 2012, In : Nucleic acids research. 40, 4, p. 1778-1786 9 p.

Research output: Contribution to journalArticle

Experimental tests of two proofreading mechanisms for 5'-splice site selection.

Wang, Y. & Silverman, S. K., Jun 20 2006, In : ACS chemical biology. 1, 5, p. 316-324 9 p.

Research output: Contribution to journalArticle

Flash decaging of tyrosine sidechains in an ion channel

Miller, J. C., Silverman, S. K., England, P. M., Dougherty, D. A. & Lester, H. A., Apr 1998, In : Neuron. 20, 4, p. 619-624 6 p.

Research output: Contribution to journalArticle