Scott E Denmark

1975 …2020
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Research Output 1975 2020

Lewis base activation of Lewis acids: Catalytic enantioselective glycolate aldol reactions

Denmark, S. E. & Chung, W. J., Feb 22 2008, In : Angewandte Chemie - International Edition. 47, 10, p. 1890-1892 3 p.

Research output: Contribution to journalArticle

glycolic acid
Lewis Bases
Lewis Acids
Acetals
Enantioselectivity

Lewis base activation of Lewis acids: Catalytic, enantioselective addition of silyl ketene acetals to aldehydes

Denmark, S. E., Beutner, G. L., Wynn, T. & Eastgate, M. D., Mar 23 2005, In : Journal of the American Chemical Society. 127, 11, p. 3774-3789 16 p.

Research output: Contribution to journalArticle

Lewis Bases
Lewis Acids
Acetals
aldehyde
Aldehydes

Lewis base activation of Lewis acids: Vinylogous aldol additions of silyl dienol ethers to aldehydes

Denmark, S. E. & Heemstra, J. R., Nov 3 2004, In : Synlett. 13, p. 2411-2416 6 p.

Research output: Contribution to journalArticle

Lewis Bases
Lewis Acids
Ethers
Aldehydes
Chemical activation
glycolic acid
Lewis Bases
Lewis Acids
Acetals
Aldehydes

Lewis base activation of Lewis acids. Addition of silyl ketene acetals to aldehydes

Denmark, S. E., Wynn, T. & Beutner, G. L., Nov 13 2002, In : Journal of the American Chemical Society. 124, 45, p. 13405-13407 3 p.

Research output: Contribution to journalArticle

Lewis Bases
Lewis Acids
Acetals
aldehyde
Aldehydes

Lewis base activation of lewis acids. Catalytic enantioselective addition of silyl enol ethers of achiral methyl ketones to aldehydes

Denmark, S. E. & Heemstra, J. R., Jun 26 2003, In : Organic Letters. 5, 13, p. 2303-2306 4 p.

Research output: Contribution to journalArticle

Lewis Bases
Methyl Ethers
Lewis Acids
Lewis base
Ethers
Lewis Bases
Lewis Acids
Acetals
Addition reactions
aldehyde

Lewis base activation of Lewis acids. Vinylogous aldol reactions

Denmark, S. E. & Beutner, G. L., Jul 2 2003, In : Journal of the American Chemical Society. 125, 26, p. 7800-7801 2 p.

Research output: Contribution to journalArticle

Lewis Bases
Lewis Acids
Ethers
ether
Chemical activation
Lewis Bases
Allylation
Lewis Acids
Aldehydes
Chemical activation

Lewis Base Catalysis: A Platform for Enantioselective Addition to Alkenes Using Group 16 and 17 Lewis Acids (n → σ*)

Kalyani, D., Kornfilt, D. J. P., Burk, M. T. & Denmark, S. E., Aug 17 2016, Lewis Base Catalysis in Organic Synthesis. Wiley-VCH Verlag, Vol. 3. p. 1153-1211 59 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Lewis Bases
Lewis Acids
Alkenes
Catalysis
Nucleophiles

Lewis base catalysis in organic synthesis

Denmark, S. E. & Beutner, G. L., Feb 15 2008, In : Angewandte Chemie - International Edition. 47, 9, p. 1560-1638 79 p.

Research output: Contribution to journalReview article

Lewis Bases
Catalysis
Lewis Acids
Acids
Protons

Lewis Base Catalysis in Organic Synthesis

Vedejs, E. & Denmark, S. E., Aug 17 2016, Wiley-VCH Verlag. 1400 p.

Research output: Book/ReportBook

Lewis Bases
Catalysis
Electrons

Lewis base catalysis of bromo- and iodolactonization, and cycloetherification

Denmark, S. E. & Burk, M. T., Nov 30 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 48, p. 20655-20660 6 p.

Research output: Contribution to journalArticle

Lewis Bases
Cyclization
Catalysis
Ions

Lewis base catalysis of the Mukaiyama directed aldol reaction: 40years of inspiration and advances

Beutner, G. L. & Denmark, S. E., Aug 26 2013, In : Angewandte Chemie - International Edition. 52, 35, p. 9086-9096 11 p.

Research output: Contribution to journalReview article

Lewis Bases
Addition reactions
Catalysis
Catalyst selectivity
Enantioselectivity

Lewis Base-Catalyzed, Asymmetric Aldol Additions of Methyl Ketone Enolates

Denmark, S. E., Stavenger, R. A. & Wong, K. T., Feb 20 1998, In : Journal of Organic Chemistry. 63, 4, p. 918-919 2 p.

Research output: Contribution to journalArticle

Lewis Bases
Ketones
3-hydroxybutanal

Lewis base catalyzed, enantioselective, intramolecular sulfenoamination of olefins

Denmark, S. E. & Chi, H. M., Jun 25 2014, In : Journal of the American Chemical Society. 136, 25, p. 8915-8918 4 p.

Research output: Contribution to journalArticle

Lewis Bases
alkene
Alkenes
Olefins
Pyrrolidines

Lewis base catalyzed, enantioselective aldol addition of methyl trichlorosilyl ketene acetal to ketones

Denmark, S. E., Fan, Y. & Eastgate, M. D., Jun 24 2005, In : Journal of Organic Chemistry. 70, 13, p. 5235-5248 14 p.

Research output: Contribution to journalArticle

Lewis Bases
Acetals
Ketones
Enantioselectivity
Bearings (structural)

Lewis Base-Catalyzed, Lewis Acid-Mediated Reactions (n → σ*)

Rossi, S. & Denmark, S. E., Aug 17 2016, Lewis Base Catalysis in Organic Synthesis. Wiley-VCH Verlag, Vol. 3. p. 1039-1076 38 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Lewis Bases
Lewis Acids
Silicon
Phosphoramides
Methyl Ethers

Lewis base catalyzed addition of trimethylsilyl cyanide to aldehydes

Denmark, S. E. & Chung, W. J., May 12 2006, In : Journal of Organic Chemistry. 71, 10, p. 4002-4005 4 p.

Research output: Contribution to journalArticle

Lewis Bases
Aldehydes
Phosphines
Amines
Enantioselectivity

Lewis base catalyzed aldol additions of chiral trichlorosilyl enolates and silyl enol ethers

Denmark, S. E., Fujimori, S. & Pham, S. M., Dec 23 2005, In : Journal of Organic Chemistry. 70, 26, p. 10823-10840 18 p.

Research output: Contribution to journalArticle

Lewis Bases
Ethers
3-Hydroxybutyric Acid
Phosphoramides
Catalysts

Lewis base catalyzed enantioselective additions of an N-silyl vinylketene imine

Denmark, S. E. & Wilson, T. W., Mar 26 2012, In : Angewandte Chemie - International Edition. 51, 13, p. 3236-3239 4 p.

Research output: Contribution to journalArticle

Lewis Bases
Stereoselectivity
Nitriles
Nucleophiles
Imines

Lewis base catalyzed enantioselective aldol addition of acetaldehyde-derived silyl enol ether to aldehydes

Denmark, S. E. & Bui, T., Nov 25 2005, In : Journal of Organic Chemistry. 70, 24, p. 10190-10193 4 p.

Research output: Contribution to journalArticle

Lewis Bases
Acetaldehyde
Aldehydes
Ether
Chlorohydrins

Ligand-mediated addition of organometallic reagents to azomethine functions

Denmark, S. E. & Nicaise, O. J. C., Jan 1 1996, In : Chemical Communications. 9, p. 999-1004 6 p.

Research output: Contribution to journalArticle

Carbonyl compounds
Nucleophiles
Organometallics
Amines
Alcohols

Lithium/Ammonia Cleavage of the N-N Bond in N-(MethoxycarbonyI)- and N-Acetylhydrazines

Denmark, S. E., Nicaise, O. & Edwards, J. P., Dec 1990, In : Journal of Organic Chemistry. 55, 25, p. 6219-6223 5 p.

Research output: Contribution to journalArticle

Hydrazones
Nucleophiles
Lithium
Ammonia
Proline

Low pressure carbonylation of epoxides to β-lactones

Kramer, J. W., Treitler, D. S., Coates, G. W., Denmark, S. E. & Hoover, A. J., Dec 1 2009, In : Organic Syntheses. 86, p. 287-297 11 p.

Research output: Contribution to journalArticle

epoxy compounds
low pressure

Mechanistic, crystallographic, and computational studies on the catalytic, enantioselective sulfenofunctionalization of alkenes

Denmark, S. E., Hartmann, E., Kornfilt, D. J. P. & Wang, H., Dec 2014, In : Nature Chemistry. 6, 12, p. 1056-1064 9 p.

Research output: Contribution to journalArticle

Alkenes
Olefins
Carbon
Sulfur
Nitrogen

Mechanistic and Stereochemical Divergence in the Allylsilane-Acetal Addition Reaction

Denmark, S. E. & Willson, T. M., Apr 1989, In : Journal of the American Chemical Society. 111, 9, p. 3475-3476 2 p.

Research output: Contribution to journalArticle

Acetals
Addition reactions
allylsilane
Fluorobenzenes
Cross Reactions
palladium
Palladium
Catalysis

Mechanistic insights into the chiral phosphoramide-catalyzed, enantioselective crossed-aldol reactions of aldehydes

Denmark, S. E. & Bui, T., Dec 9 2005, In : Journal of Organic Chemistry. 70, 25, p. 10393-10399 7 p.

Research output: Contribution to journalArticle

Aldehydes
Chemical activation
Isotopes
Addition reactions
Kinetics

Mechanistic significance of the Si-O-Pd bond in the palladium-catalyzed cross-coupling reactions of alkenylsilanolates

Tymonko, S. A., Smith, R. C., Ambrosi, A. & Denmark, S. E., May 20 2015, In : Journal of the American Chemical Society. 137, 19, p. 6192-6199 8 p.

Research output: Contribution to journalArticle

Open Access
phosphine
cesium
Cross Reactions
palladium
Palladium

Mechanistic significance of the Si-O-Pd bond in the palladium-catalyzed cross-coupling reactions of arylsilanolates

Tymonko, S. A., Smith, R. C., Ambrosi, A., Ober, M. H., Wang, H. & Denmark, S. E., May 20 2015, In : Journal of the American Chemical Society. 137, 19, p. 6200-6218 19 p.

Research output: Contribution to journalArticle

Open Access
Cross Reactions
palladium
Palladium
phosphine
Hot Temperature

Mild and general cross-coupling of (α-alkoxyvinyl)silanols and -silyl hydrides

Denmark, S. E. & Neuville, L., Oct 5 2000, In : Organic Letters. 2, 20, p. 3221-3224 4 p.

Research output: Contribution to journalArticle

cross coupling
Hydrides
hydrides
Cross Reactions
Palladium

Modified proline auxiliaries for selective addition of organocerium reagents to hydrazones

Weber, T., Edwards, J. P. & Denmark, S. E., Sep 1989, In : Synlett. 1989, 1, p. 20-22 3 p.

Research output: Contribution to journalArticle

Hydrazones
Proline
Hydrazines
Nucleophiles
pyrrolidine
Hempa
Silicon
Isomers
Single crystals
X rays

New synthetic methods. III: Preface

Denmark, S. E., Jan 1 1992, In : Tetrahedron. 48, 11

Research output: Contribution to journalEditorial

New vistas in organoelement chemistry

Denmark, S. E., Christenson, B. L., O'Connor, S. P. & Murase, N., Jan 1996, In : Pure and Applied Chemistry. 68, 1, p. 23-27 5 p.

Research output: Contribution to journalArticle

Alcohols
Enantioselectivity
Substitution reactions
Zinc
allyl alcohol
Pyrrolidines
Cycloaddition
Lewis Acids
Ethers
Ether
Pyrrolidines
Cycloaddition
Lactams
Hydrogenolysis
Nickel

Nitroalkene Inter [4 + 2]/Intra [3 + 2] Tandem Cycloadditions. 7. Application of (R)-(-)-2,2-Diphenylcyclopentanol as the Chiral Auxiliary

Denmark, S. E., Schnute, M. E., Marcin, L. R. & Thorarensen, A., May 1 1995, In : Journal of Organic Chemistry. 60, 10, p. 3205-3220 16 p.

Research output: Contribution to journalArticle

Cycloaddition
Ethers
Boranes
Lewis Acids
Hydrogenolysis

N-silyl oxyketene imines are underused yet highly versatile reagents for catalytic asymmetric synthesis

Denmark, S. E. & Wilson, T. W., Nov 1 2010, In : Nature Chemistry. 2, 11, p. 937-943 7 p.

Research output: Contribution to journalArticle

Imines
Benzoin
Anions
Negative ions
glycolic acid

Observation of direct sulfenium and selenenium group transfer from thiiranium and seleniranium ions to alkenes

Denmark, S. E., Collins, W. R. & Cullen, M. D., Mar 18 2009, In : Journal of the American Chemical Society. 131, 10, p. 3490-3492 3 p.

Research output: Contribution to journalArticle

alkene
Alkenes
Olefins
Observation
Ions

One-flask synthesis of methyl arylvinyldiazoacetates and their application in enantioselective C–H functionalization: synthesis of (E)-methyl 2-diazo-4-phenylbut-3-enoate and (S,E)methyl 2-((R)-4-methyl-1,2-dihydronaphthalen-2-YL)-4-phenylbut-3-enoate

Manning, J. R., Davies, H. M. L., Denmark, S. E. & Collins, W. R., Jan 1 2007, Organic Syntheses. Wiley Blackwell, p. 334-346 13 p. (Organic Syntheses; vol. 84).

Research output: Chapter in Book/Report/Conference proceedingChapter

flasks
synthesis
diazo-4

On the absolute configurational stability of bromonium and chloronium ions

Denmark, S. E., Burk, M. T. & Hoover, A. J., Feb 3 2010, In : Journal of the American Chemical Society. 132, 4, p. 1232-1233 2 p.

Research output: Contribution to journalArticle

Alkenes
Olefins
Ions
ion
alkene

On the Generation and Configurational Stability of (2S,3S)-1,2,3-TriphenyIborirane

Denmark, S. E., Nishide, K. & Faucher, A. M., Aug 1 1991, In : Journal of the American Chemical Society. 113, 17, p. 6675-6676 2 p.

Research output: Contribution to journalArticle

On the lewis acid induced addition of allylstannanes to aldehydes: A spectroscopic investigation

Denmark, S. E., Wilson, T. & Willson, T. M., Feb 1988, In : Journal of the American Chemical Society. 110, 3, p. 984-986 3 p.

Research output: Contribution to journalArticle

Lewis Acids
Aldehydes
Lewis Bases
Allylation
Aldehydes

On the mechanism of Lewis base catalyzed aldol addition reactions: Kinetic and spectroscopic investigations using rapid-injection NMR

Denmark, S. E., Eklov, B. M., Yao, P. J. & Eastgate, M. D., Aug 26 2009, In : Journal of the American Chemical Society. 131, 33, p. 11770-11787 18 p.

Research output: Contribution to journalArticle

Lewis Bases
Addition reactions
reaction kinetics
silicon
nuclear magnetic resonance

On the mechanism of the selenolactonization reaction with selenenyl halides

Denmark, S. E. & Edwards, M. G., Sep 15 2006, In : Journal of Organic Chemistry. 71, 19, p. 7293-7306 14 p.

Research output: Contribution to journalArticle

Bromides
Esters
Acids
Cyclization
Isomerization

On the mechanism of the Skraup-Doebner-Von Miller quinoline synthesis

Denmark, S. E. & Venkatraman, S., Feb 17 2006, In : Journal of Organic Chemistry. 71, 4, p. 1668-1676 9 p.

Research output: Contribution to journalArticle

Ketones
Labels
Aniline Compounds
Quinolines
Imines

On the stereochemical course of palladium-catalyzed cross-coupling of allylic silanolate salts with aromatic bromides

Denmark, S. E. & Werner, N. S., Mar 17 2010, In : Journal of the American Chemical Society. 132, 10, p. 3612-3620 9 p.

Research output: Contribution to journalArticle

palladium
Palladium
Bromides
bromide
Salts