Sayeepriyadarshini Anakk

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2020

Bile acid treatment and FXR agonism lower postprandial lipemia in mice

Farr, S., Stankovic, B., Hoffman, S., Masoudpoor, H., Baker, C., Taher, J., Dean, A. E., Anakk, S. & Adeli, K., 2020, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 318, 4, p. H682-G693

Research output: Contribution to journalArticle

2019

Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration

Pepe-Mooney, B. J., Dill, M. T., Alemany, A., Ordovas-Montanes, J., Matsushita, Y., Rao, A., Sen, A., Miyazaki, M., Anakk, S., Dawson, P. A., Ono, N., Shalek, A. K., van Oudenaarden, A. & Camargo, F. D., Jul 3 2019, In : Cell Stem Cell. 25, 1, p. 23-38.e8

Research output: Contribution to journalArticle

Small Heterodimer Partner Regulates Dichotomous T Cell Expansion by Macrophages

Shahoei, S. H., Kim, Y. C., Cler, S. J., Ma, L., Anakk, S., Kemper, J. K. & Nelson, E. R., 2019, In : Endocrinology. 160, 7, p. 1573-1589 17 p.

Research output: Contribution to journalArticle

2018

Alternative splicing rewires Hippo signaling pathway in hepatocytes to promote liver regeneration

Bangru, S., Arif, W., Seimetz, J., Bhate, A., Chen, J., Rashan, E. H., Carstens, R. P., Anakk, S. & Kalsotra, A., Oct 2018, In : Nature Structural and Molecular Biology. 25, 10, p. 928-939 12 p.

Research output: Contribution to journalArticle

Identification of IQ motif-containing GTPase-activating protein 1 as a regulator of long-term ketosis

Erickson, H. L. & Anakk, S., Nov 2 2018, In : JCI Insight. 3, 21

Research output: Contribution to journalArticle

Xenobiotic nuclear receptor signaling determines molecular pathogenesis of progressive familial intrahepatic cholestasis

Kim, K. H., Choi, J. M., Li, F., Arizpe, A., Wooton-Kee, C. R., Anakk, S., Jung, S. Y., Finegold, M. J. & Moore, D. D., Jun 1 2018, In : Endocrinology. 159, 6, p. 2435-2446 12 p.

Research output: Contribution to journalArticle

2017

Bile acid excess induces cardiomyopathy and metabolic dysfunctions in the heart

Desai, M. S., Mathur, B., Eblimit, Z., Vasquez, H., Taegtmeyer, H., Karpen, S. J., Penny, D. J., Moore, D. D. & Anakk, S., Jan 1 2017, In : Hepatology. 65, 1, p. 189-201 13 p.

Research output: Contribution to journalArticle

Hepatic FXR/SHP axis modulates systemic glucose and fatty acid homeostasis in aged mice

Kim, K. H., Choi, S., Zhou, Y., Kim, E. Y., Lee, J. M., Saha, P. K., Anakk, S. & Moore, D. D., Aug 2017, In : Hepatology. 66, 2, p. 498-509 12 p.

Research output: Contribution to journalArticle

Small heterodimer partner deletion prevents hepatic steatosis and when combined with farnesoid X receptor loss protects against type 2 diabetes in mice

Akinrotimi, O., Riessen, R., VanDuyne, P., Park, J. E., Lee, Y. K., Wong, L. J., Zavacki, A. M., Schoonjans, K. & Anakk, S., Dec 2017, In : Hepatology. 66, 6, p. 1854-1865 12 p.

Research output: Contribution to journalArticle

2015

ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation

Bhate, A., Parker, D. J., Bebee, T. W., Ahn, J., Arif, W., Rashan, E. H., Chorghade, S., Chau, A., Lee, J. H., Anakk, S., Carstens, R. P., Xiao, X. & Kalsotra, A., Nov 4 2015, In : Nature communications. 6, 8768.

Research output: Contribution to journalArticle

2014

Cysteine sulfinic acid decarboxylase regulation: A role for farnesoid X receptor and small heterodimer partner in murine hepatic taurine metabolism

Kerr, T. A., Matsumoto, Y., Matsumoto, H., Xie, Y., Hirschberger, L. L., Stipanuk, M. H., Anakk, S., Moore, D. D., Watanabe, M., Kennedy, S. & Davidson, N. O., Oct 1 2014, In : Hepatology Research. 44, 10, p. E218-E228

Research output: Contribution to journalArticle

Vitamin D receptor activation down-regulates the small heterodimer partner and increases CYP7A1 to lower cholesterol

Chow, E. C. Y., Magomedova, L., Quach, H. P., Patel, R., Durk, M. R., Fan, J., Maeng, H. J., Irondi, K., Anakk, S., Moore, D. D., Cummins, C. L. & Pang, K. S., Apr 2014, In : Gastroenterology. 146, 4, p. 1048-1059.e7

Research output: Contribution to journalArticle

2013

Bile Acids Activate YAP to Promote Liver Carcinogenesis

Anakk, S., Bhosale, M., Schmidt, V. A., Johnson, R. L., Finegold, M. J. & Moore, D. D., Nov 27 2013, In : Cell Reports. 5, 4, p. 1060-1069 10 p.

Research output: Contribution to journalArticle

Farnesoid X receptor inhibits gankyrin in mouse livers and prevents development of liver cancer

Jiang, Y., Iakova, P., Jin, J., Sullivan, E., Sharin, V., Hong, I. H., Anakk, S., Mayor, A., Darlington, G., Finegold, M., Moore, D. & Timchenko, N. A., Mar 1 2013, In : Hepatology. 57, 3, p. 1098-1106 9 p.

Research output: Contribution to journalArticle

2011

Bile acid receptor agonist GW4064 regulates PPARγ coactivator-1α expression through estrogen receptor-related receptor α

Dwivedi, S. K. D., Singh, N., Kumari, R., Mishra, J. S., Tripathi, S., Banerjee, P., Shah, P., Kukshal, V., Tyagi, A. M., Gaikwad, A. N., Chaturvedi, R. K., Mishra, D. P., Trivedi, A. K., Sanyal, S., Chattopadhyay, N., Ramachandran, R., Siddiqi, M. I., Bandyopadhyay, A., Arora, A., Lundåsen, T. & 3 others, Anakk, S. P., Moore, D. D. & Sanyal, S., Jun 2011, In : Molecular Endocrinology. 25, 6, p. 922-932 11 p.

Research output: Contribution to journalArticle

Combined deletion of Fxr and Shp in mice induces Cyp17a1 and results in juvenile onset cholestasis

Anakk, S., Watanabe, M., Ochsner, S. A., McKenna, N. J., Finegold, M. J. & Moore, D. D., Jan 4 2011, In : Journal of Clinical Investigation. 121, 1, p. 86-95 10 p.

Research output: Contribution to journalArticle

Dissociation of diabetes and obesity in mice lacking orphan nuclear receptor small heterodimer partner

Park, Y. J., Kim, S. C., Kim, J., Anakk, S., Lee, J. M., Tseng, H. T., Yechoor, V., Park, J., Choi, J. S., Jang, H. C., Lee, K. U., Novak, C. M., Moore, D. D. & Lee, Y. K., Dec 1 2011, In : Journal of Lipid Research. 52, 12, p. 2234-2244 11 p.

Research output: Contribution to journalArticle

2007

Brain trauma leads to enhanced lung inflammation and injury: Evidence for role of P4504Fs in resolution

Kalsotra, A., Zhao, J., Anakk, S., Dash, P. K. & Strobel, H. W., May 16 2007, In : Journal of Cerebral Blood Flow and Metabolism. 27, 5, p. 963-974 12 p.

Research output: Contribution to journalArticle

Catalytic characterization and cytokine mediated regulation of cytochrome P450 4Fs in rat hepatocytes

Kalsotra, A., Anakk, S., Brommer, C. L., Kikuta, Y., Morgan, E. T. & Strobel, H. W., May 1 2007, In : Archives of Biochemistry and Biophysics. 461, 1, p. 104-112 9 p.

Research output: Contribution to journalArticle

Gender dictates the nuclear receptor-mediated regulation of CYP3A44

Anakk, S., Huang, W., Staudinger, J. L., Tan, K., Cole, T. J., Moore, D. D. & Strobel, H. W., 2007, In : Drug Metabolism and Disposition. 35, 1, p. 36-42 7 p.

Research output: Contribution to journalArticle

2004

CAR/PXR provides directives for Cyp3a41 gene regulation differently from Cyp3a11

Anakk, S., Kalsotra, A., Kikuta, Y., Huang, W., Zhang, J., Staudinger, J. L., Moore, D. D. & Strobel, H. W., Jan 1 2004, In : Pharmacogenomics Journal. 4, 2, p. 91-101 11 p.

Research output: Contribution to journalArticle

2003

Genomic characterization and regulation of CYP3a13: role of xenobiotics and nuclear receptors.

Anakk, S., Kalsotra, A., Shen, Q., Vu, M. T., Staudinger, J. L., Davies, P. J. A. & Strobel, H. W., Sep 2003, In : The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 17, 12, p. 1736-1738 3 p.

Research output: Contribution to journalArticle

Insights into gender bias: Rat cytochrome P450 3A9

Anakk, S., Ku, C. Y., Vore, M. & Strobel, H. W., May 1 2003, In : Journal of Pharmacology and Experimental Therapeutics. 305, 2, p. 703-709 7 p.

Research output: Contribution to journalArticle

2002

Sexual dimorphism and tissue specificity in the expression of CYP4F forms in Sprague Dawley rats

Kalsotra, A., Anakk, S., Boehme, C. L. & Strobel, H. W., Sep 1 2002, In : Drug Metabolism and Disposition. 30, 9, p. 1022-1028 7 p.

Research output: Contribution to journalArticle

2000

Immobilization stress-induced changes in brain acetylcholinesterase activity and cognitive function in mice

Das, A., Kapoor, K., Sayeepriyadarshini, A. T., Dikshit, M., Palit, G. & Nath, C., Jan 1 2000, In : Pharmacological Research. 42, 3, p. 213-217 5 p.

Research output: Contribution to journalArticle