Satish K Nair

1991 …2019
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Biosynthesis Chemical Compounds
Enzymes Medicine & Life Sciences
Carbonic Anhydrase II Chemical Compounds
Peptides Medicine & Life Sciences
Catalytic Domain Medicine & Life Sciences
Substrates Chemical Compounds
Biological Products Medicine & Life Sciences
Crystal structure Chemical Compounds

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Research Output 1991 2019

Biosynthesis of the RiPP trojan horse nucleotide antibiotic microcin C is directed by the N-formyl of the peptide precursor

Dong, S. H., Kulikovsky, A., Zukher, I., Estrada, P., Dubiley, S., Severinov, K. & Nair, S. K., Jan 1 2019, In : Chemical Science. 10, 8, p. 2391-2395 5 p.

Research output: Contribution to journalArticle

Open Access
Biosynthesis
Nucleotides
Anti-Bacterial Agents
Peptides
Ubiquitin-Activating Enzymes

Characterization of glutamyl-tRNA–dependent dehydratases using nonreactive substrate mimics

Bothwell, I. R., Cogan, D. P., Kim, T., Reinhardt, C. J., van der Donk, W. A. & Nair, S. K., Aug 27 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 35, p. 17245-17250 6 p.

Research output: Contribution to journalArticle

Open Access
Hydro-Lyases
RNA, Transfer, Glu
Peptides
Nisin
Glutamic Acid

Characterization of the flavin monooxygenase involved in biosynthesis of the antimalarial FR-900098

Nguyen, K., DeSieno, M. A., Bae, B., Johannes, T. W., Cobb, R. E., Zhao, H. & Nair, S. K., Jan 1 2019, In : Organic and Biomolecular Chemistry. 17, 6, p. 1506-1518 13 p.

Research output: Contribution to journalArticle

dimethylaniline monooxygenase (N-oxide forming)
Flavin-Adenine Dinucleotide
biosynthesis
Biosynthesis
Antimalarials

Insights into AMS/PCAT transporters from biochemical and structural characterization of a double Glycine motif protease

Bobeica, S. C., Dong, S. H., Huo, L., Mazo, N., McLaughlin, M. I., Jiménez-Osés, G., Nair, S. K. & van der Donk, W. A., Jan 14 2019, In : eLife. 8

Research output: Contribution to journalArticle

Protein Sorting Signals
Glycine
Peptide Hydrolases
Bacteria
Peptides

Mechanistic Basis for Ribosomal Peptide Backbone Modifications

Dong, S. H., Liu, A., Mahanta, N., Mitchell, D. A. & Nair, S. K., Jan 1 2019, In : ACS Central Science.

Research output: Contribution to journalArticle

Open Access
Peptides
Enzymes
Thioamides
Substrates
Coenzymes