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2018

A Post-Transcriptional Feedback Mechanism for Noise Suppression and Fate Stabilization

Hansen, M. M. K., Wen, W. Y., Ingerman, E., Razooky, B. S., Thompson, C. E., Dar, R. D., Chin, C. W., Simpson, M. L. & Weinberger, L. S., Jun 14 2018, In : Cell. 173, 7, p. 1609-1621.e15

Research output: Contribution to journalArticle

Cell Size-Based Decision-Making of a Viral Gene Circuit

Bohn-Wippert, K., Tevonian, E. N., Lu, Y., Huang, M. Y., Megaridis, M. R. & Dar, R. D., Dec 26 2018, In : Cell Reports. 25, 13, p. 3844-3857.e5

Research output: Contribution to journalArticle

2017

Similarity in viral and host promoters couples viral reactivation with host cell migration

Bohn-Wippert, K., Tevonian, E. N., Megaridis, M. R. & Dar, R. D., Jan 1 2017, In : Nature communications. 8, 15006.

Research output: Contribution to journalArticle

2016

Transcriptional bursting explains the noise-versus-mean relationship in mRNA and protein levels

Dar, R. D., Shaffer, S. M., Singh, A., Razooky, B. S., Simpson, M. L., Raj, A. & Weinberger, L. S., Jul 2016, In : PloS one. 11, 7, e0158298.

Research output: Contribution to journalArticle

2015

The low noise limit in gene expression

Dar, R. D., Razooky, B. S., Weinberger, L. S., Cox, C. D. & Simpson, M. L., Oct 21 2015, In : PloS one. 10, 10, e0140969.

Research output: Contribution to journalArticle

2014

Screening for noise in gene expression identifies drug synergies

Dar, R. D., Hosmane, N. N., Arkin, M. R., Siliciano, R. F. & Weinberger, L. S., Jan 1 2014, In : Science. 344, 6190, p. 1392-1396 5 p.

Research output: Contribution to journalArticle

2013

BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism

Boehm, D., Calvanese, V., Dar, R. D., Xing, S., Schroeder, S., Martins, L., Aull, K., Li, P. C., Planelles, V., Bradner, J. E., Zhou, M. M., Siliciano, R. F., Weinberger, L., Verdin, E. & Ott, M., Feb 1 2013, In : Cell Cycle. 12, 3, p. 452-462 11 p.

Research output: Contribution to journalArticle

2012

An endogenous accelerator for viral gene expression confers a fitness advantage

Teng, M. W., Bolovan-Fritts, C., Dar, R. D., Womack, A., Simpson, M. L., Shenk, T. & Weinberger, L. S., Dec 21 2012, In : Cell. 151, 7, p. 1569-1580 12 p.

Research output: Contribution to journalArticle

Dynamics of protein noise can distinguish between alternate sources of gene-expression variability

Singh, A., Razooky, B. S., Dar, R. D. & Weinberger, L. S., Sep 17 2012, In : Molecular Systems Biology. 8, 201238.

Research output: Contribution to journalArticle

Transcriptional burst frequency and burst size are equally modulated across the human genome

Dar, R. D., Razooky, B. S., Singh, A., Trimeloni, T. V., McCollum, J. M., Cox, C. D., Simpson, M. L. & Weinberger, L. S., Oct 23 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 43, p. 17454-17459 6 p.

Research output: Contribution to journalArticle

2011

Model for biological communication in a nanofabricated cell-mimic driven by stochastic resonance

Karig, D. K., Siuti, P., Dar, R. D., Retterer, S. T., Doktycz, M. J. & Simpson, M. L., Mar 1 2011, In : Nano Communication Networks. 2, 1, p. 39-49 11 p.

Research output: Contribution to journalArticle

2008

Transient-mediated fate determination in a transcriptional circuit of HIV

Weinberger, L. S., Dar, R. D. & Simpson, M. L., Apr 1 2008, In : Nature Genetics. 40, 4, p. 466-470 5 p.

Research output: Contribution to journalArticle

Using noise to probe and characterize gene circuits

Cox, C. D., McCollum, J. M., Allen, M. S., Dar, R. D. & Simpson, M. L., Aug 5 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 31, p. 10809-10814 6 p.

Research output: Contribution to journalArticle

2006

Frequency domain analysis of noise in simple gene circuits

Cox, C. D., McCollum, J. M., Austin, D. W., Allen, M. S., Dar, R. D. & Simpson, M. L., Jan 1 2006, In : Chaos. 16, 2, 026102.

Research output: Contribution to journalArticle