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Research Output 1998 2019

Work in progress: Reviving a transport phenomena course by incorporating simulation and laboratory experiences

Pool, M., Bhargava, R., Jensen, P. A. & Jensen, K., Jun 26 2016, 2016 ASEE Annual Conference and Exposition. American Society for Engineering Education, Vol. 2016-June.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Vibrational spectroscopy and imaging for concurrent cellular trafficking of co-localized doxorubicin and deuterated phospholipid vesicles

Misra, S. K., Mukherjee, P., Ohoka, A., Schwartz-Duval, A. S., Tiwari, S., Bhargava, R. & Pan, D., Feb 7 2016, In : Nanoscale. 8, 5, p. 2826-2831 6 p.

Research output: Contribution to journalArticle

Vibrational spectroscopy
Phospholipids
Doxorubicin
Nanoparticles
Imaging techniques

Validating the cancer diagnosis potential of mid-infrared spectroscopic imaging

Pounder, F. N., Reddy, R. K., Walsh, M. J. & Bhargava, R., Jun 15 2009, Optical Diagnostics and Sensing IX. 71860f. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 7186).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Spectral resolution
Coloring Agents
Dyes
Pixels
cancer

Using Fourier transform IR spectroscopy to analyze biological materials

Baker, M. J., Trevisan, J., Bassan, P., Bhargava, R., Butler, H. J., Dorling, K. M., Fielden, P. R., Fogarty, S. W., Fullwood, N. J., Heys, K. A., Hughes, C., Lasch, P., Martin-Hirsch, P. L., Obinaju, B., Sockalingum, G. D., Sulé-Suso, J., Strong, R. J., Walsh, M. J., Wood, B. R., Gardner, P. & 1 others, Martin, F. L., Aug 2014, In : Nature Protocols. 9, 8, p. 1771-1791 21 p.

Research output: Contribution to journalArticle

Fourier Analysis
Biological materials
Infrared spectroscopy
Spectrum Analysis
Fourier transforms

Tunable multilayered nanospheres as probes for surface-enhanced Raman spectroscopy

Kodali, A. K. & Bhargava, R., Nov 24 2008, Plasmonics: Metallic Nanostructures and Their Optical Properties VI. 70320V. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 7032).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Nanospheres
Raman Spectroscopy
Raman spectroscopy
Probe
Enhancement

Tunable Luminescent Carbon Nanospheres with Well-Defined Nanoscale Chemistry for Synchronized Imaging and Therapy

Mukherjee, P., Misra, S. K., Gryka, M. C., Chang, H. H., Tiwari, S., Wilson, W. L., Scott, J. W., Bhargava, R. & Pan, D., Sep 1 2015, In : Small. 11, 36, p. 4691-4703 13 p.

Research output: Contribution to journalArticle

Nanospheres
Photoluminescence
Carbon
Nanostructures
Surface chemistry

Translation of infrared chemical imaging for cardiovascular evaluation

Tiwari, S., Raman, J., Reddy, V., Dawson, M. & Bhargava, R., Jan 1 2016, Biomedical Vibrational Spectroscopy 2016: Advances in Research and Industry. Mahadevan-Jansen, A. & Petrich, W. (eds.). SPIE, 97040X. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 9704).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Infrared imaging
Fourier Analysis
Infrared radiation
Imaging techniques
histology

Towards Translation of Discrete Frequency Infrared Spectroscopic Imaging for Digital Histopathology of Clinical Biopsy Samples

Tiwari, S., Raman, J., Reddy, V., Ghetler, A., Tella, R. P., Han, Y., Moon, C. R., Hoke, C. D. & Bhargava, R., Oct 18 2016, In : Analytical chemistry. 88, 20, p. 10183-10190 8 p.

Research output: Contribution to journalArticle

Biopsy
Infrared imaging
Infrared radiation
Imaging techniques
Fourier transforms

Towards faster FT-IR imaging by reducing noise

Bhargava, R., Ribar, T. & Koenig, J. L., Nov 1999, In : Applied Spectroscopy. 53, 11, p. 1313-1322 10 p.

Research output: Contribution to journalArticle

Infrared imaging
Fast Fourier transforms
Signal to noise ratio
acquisition
dissolving

Towards better than human capability in diagnosing prostate cancer using infrared spectroscopic imaging

Llorá, X., Reddy, R., Matesic, B. & Bhargava, R., Aug 27 2007, Proceedings of GECCO 2007: Genetic and Evolutionary Computation Conference. p. 2098-2105 8 p. (Proceedings of GECCO 2007: Genetic and Evolutionary Computation Conference).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Prostate Cancer
Infrared
Imaging
Infrared radiation
Imaging techniques
Fourier Analysis
Fourier transforms
Spectral resolution
Signal-To-Noise Ratio
Pathology

Time-resolved Fourier transform infrared spectroscopic imaging

Bhargava, R. & Levin, I. W., Apr 1 2003, In : Applied Spectroscopy. 57, 4, p. 357-366 10 p.

Research output: Contribution to journalArticle

Fourier transforms
examination
Infrared radiation
Imaging techniques
Correlation methods

Three-dimensional in silico breast phantoms for multimodal image simulations

Mahr, D. M., Bhargava, R. & Insana, M. F., Mar 1 2012, In : IEEE Transactions on Medical Imaging. 31, 3, p. 689-697 9 p., 6074946.

Research output: Contribution to journalArticle

Computer Simulation
Breast
Cytology
Tissue
Ultrasonography

Thermomechanical sensitivity of microcantilevers in the mid-infrared spectral region

Kwon, B., Wang, C., Park, K., Bhargava, R. & King, W. P., Jan 1 2011, In : Nanoscale and Microscale Thermophysical Engineering. 15, 1, p. 16-27 12 p.

Research output: Contribution to journalArticle

Infrared radiation
sensitivity
monochromators
Monochromators
Optical systems

Theory of mid-infrared absorption microspectroscopy: II. Heterogeneous samples

Davis, B. J., Carney, P. S. & Bhargava, R., May 1 2010, In : Analytical chemistry. 82, 9, p. 3487-3499 13 p.

Research output: Contribution to journalArticle

Infrared absorption
Imaging techniques
Vibrational spectroscopy
Photoresists
Optical microscopy

Theory of midinfrared absorption microspectroscopy: I. Homogeneous samples.

Davis, B. J., Carney, P. S. & Bhargava, R., May 1 2010, In : Analytical chemistry. 82, 9, p. 3474-3486 13 p.

Research output: Contribution to journalArticle

Maxwell equations
Substrates
Photoresists
Wave propagation
Spectrometers

Theory of infrared microspectroscopy for intact fibers

Davis, B. J., Scott Carney, P. & Bhargava, R., Jan 15 2011, In : Analytical chemistry. 83, 2, p. 525-532 8 p.

Research output: Contribution to journalArticle

Infrared radiation
Fibers
Cosmetics
Imaging techniques
Wavelength

Theory and application of gain ranging to Fourier transform infrared spectroscopic imaging

Bhargava, R., Fernandez, D. C., Schaeberle, M. D. & Levin, I. W., Dec 1 2001, In : Applied Spectroscopy. 55, 12, p. 1580-1589 10 p.

Research output: Contribution to journalArticle

Focal plane arrays
Fourier transforms
Infrared radiation
Imaging techniques
focal plane devices

The Chemistry of Thought: The Role of the Measurement Sciences in Brain Research

Andrews, A. M., Bhargava, R., Kennedy, R., Li, L. & Sweedler, J. V., May 2 2017, In : Analytical chemistry. 89, 9, 1 p.

Research output: Contribution to journalEditorial

The author file: Rohit Bhargava and Carol Hirschmug. Interview by Monya Baker.

Bhargava, R. & Hirschmug, C., May 1 2011, In : Nature Methods. 8, 5, 1 p.

Research output: Contribution to journalArticle

Infrared Spectrophotometry
Synchrotrons
Computer-Assisted Image Processing
Cooperative Behavior
Interviews

Synchrotron FTIR imaging for the identification of cell types within human tissues

Walsh, M. J., Nasse, M. J., Pounder, F. N., Macias, V., Kajdacsy-Balla, A., Hirschmugl, C. & Bhargava, R., Feb 22 2010, WIRMS 2009 - 5th International Workshop on Infrared Microscopy and Spectroscopy with Accelerator Based Sources. p. 105-107 3 p. (AIP Conference Proceedings; vol. 1214).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

synchrotrons
infrared spectroscopy
cells
diffraction
breast

Surface-enhanced Raman spectroscopy of polyelectrolyte-wrapped gold nanoparticles in colloidal suspension

Sivapalan, S. T., Devetter, B. M., Yang, T. K., Schulmerich, M. V., Bhargava, R. & Murphy, C. J., May 23 2013, In : Journal of Physical Chemistry C. 117, 20, p. 10677-10682 6 p.

Research output: Contribution to journalArticle

Polyelectrolytes
Gold
colloids
Raman spectroscopy
Suspensions

Subcellular localization of early biochemical transformations in cancer-activated fibroblasts using infrared spectroscopic imaging

Holton, S. E., Walsh, M. J. & Bhargava, R., Jul 21 2011, In : Analyst. 136, 14, p. 2953-2958 6 p.

Research output: Contribution to journalArticle

Fibroblasts
tumor
cancer
Infrared radiation
Imaging techniques

Studying polymer-dispersed liquid-crystal formation by FTIR spectroscopy. 2. Phase separation and ordering

Bhargava, R., Wang, S. Q. & Koenig, J. L., Dec 28 1999, In : Macromolecules. 32, 26, p. 8989-8995 7 p.

Research output: Contribution to journalArticle

Liquid crystal polymers
Phase separation
Liquid Crystals
Spectroscopy
Liquid crystals

Studying polymer-dispersed liquid-crystal formation by FTIR spectroscopy. 1. Monitoring curing reactions

Bhargava, R., Wang, S. Q. & Koenig, J. L., Dec 28 1999, In : Macromolecules. 32, 26, p. 8982-8988 7 p.

Research output: Contribution to journalArticle

Liquid crystal polymers
Liquid Crystals
Curing
Liquid crystals
Spectroscopy

Structural and biochemical characterization of engineered tissue using FTIR spectroscopic imaging: Melanoma progression as an example

Bhargava, R. & Kong, R., Apr 21 2008, Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurements of Tissue. 687004. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 6870).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fourier transforms
Tissue
Infrared radiation
Imaging techniques
Tumors

Spectroscopy for intact particles

Dijk, T. V., Bhargava, R. & Scott Carney, P., Dec 1 2012, Computational Optical Sensing and Imaging, COSI 2012. (Computational Optical Sensing and Imaging, COSI 2012).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microscopic examination
Physics
Spectroscopy
chemistry
microscopy

Spectrochemical Analysis Using Infrared Multichannel Detectors

Bhargava, R. & Levin, I. W., Nov 12 2007, Blackwell Publishing Ltd. 308 p.

Research output: Book/ReportBook

Infrared detectors
Vibrational spectroscopy
Materials science
Chemical analysis

Spectral Pathology: General discussion

Sammon, C., Schultz, Z. D., Kazarian, S., Barr, H., Goodacre, R., Graham, D., Baker, M. J., Gardner, P., Wood, B., Campbell, C. J., Dluhy, R., El-Mashtoly, S., Phillips, C., Frost, J., Diem, M., Kohler, A., Haris, P., Apolonskiy, A., Amrania, H., Lasch, P. & 10 others, Zhang, Z., Petrich, W., Sockalingum, G. D., Stone, N., Gerwert, K., Notingher, I., Bhargava, R., Kröger-Lui, N., Isabelle, M. & Pilling, M., Jan 1 2016, In : Faraday Discussions. 187, p. 155-186 32 p.

Research output: Contribution to journalArticle

Pathology

Spectral histology of breast tissue using mid-infrared spectroscopic imaging

Pounder, F. N. & Bhargava, R., Jun 1 2009, In : Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 7182, 718206.

Research output: Contribution to journalConference article

Histology
histology
breast
Breast
Molecular spectroscopy

Soft embossing of nanoscale optical and plasmonic structures in glass

Yao, J., Le, A. P., Schulmerich, M. V., Maria, J., Lee, T. W., Gray, S. K., Bhargava, R., Rogers, J. A. & Nuzzo, R. G., Jul 26 2011, In : ACS Nano. 5, 7, p. 5763-5774 12 p.

Research output: Contribution to journalArticle

embossing
Glass
Crystals
glass
crystals

Single cell analysis/data handling: General discussion

Baker, M. J., Goodacre, R., Sammon, C., Marques, M. P., Gardner, P., Tipping, W., Sulé-Suso, J., Wood, B., Byrne, H. J., Hermes, M., Matousek, P., Campbell, C. J., El-Mashtoly, S., Frost, J., Phillips, C., Diem, M., Kohler, A., Lau, K., Kazarian, S., Petrich, W. & 15 others, Lloyd, G., Delfino, I., Cinque, G., Isabelle, M., Stone, N., Kendall, C., Jamieson, L., Perez-Guaita, D., Clark, L., Gerwert, K., Notingher, I., Quaroni, L., Bhargava, R., Meade, A. & Lyng, F., Jan 1 2016, In : Faraday Discussions. 187, p. 299-327 29 p.

Research output: Contribution to journalArticle

Single-Cell Analysis
Papillomavirus Infections
Raman Spectrum Analysis
Uterine Cervical Neoplasms
Sensitivity and Specificity

Simultaneous cancer and tumor microenvironment subtyping using confocal infrared microscopy for all-digital molecular histopathology

Mittal, S., Yeh, K., Suzanne Leslie, L., Kenkel, S., Kajdacsy-Balla, A. & Bhargava, R., Jun 19 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 25, p. E5651-E5660

Research output: Contribution to journalArticle

Tumor Microenvironment
Confocal Microscopy
Breast
Epithelial Cells
Research

Selecting optimal features from Fourier transform infrared spectroscopy for discrete-frequency imaging

Mankar, R., Walsh, M. J., Bhargava, R., Prasad, S. & Mayerich, D., Mar 7 2018, In : Analyst. 143, 5, p. 1147-1156 10 p.

Research output: Contribution to journalArticle

Histology
histology
Fourier Transform Infrared Spectroscopy
FTIR spectroscopy
Fourier transform infrared spectroscopy

Sculpting the analytical volume in and around nanoparticle sensors using a multilayer geometry

Kodali, A. K., Schulmerich, M., Palekar, R. & Bhargava, R., Apr 16 2013, In : Analytical chemistry. 85, 8, p. 3842-3848 7 p.

Research output: Contribution to journalArticle

Multilayers
Metals
Nanoparticles
Geometry
Electric fields

Sculpting narrowband Fano resonances inherent in the large-area mid-infrared photonic crystal microresonators for spectroscopic imaging

Liu, J. N., Schulmerich, M. V., Bhargava, R. & Cunningham, B. T., Jan 1 2014, In : Optics Express. 22, 15, p. 18142-18158 17 p.

Research output: Contribution to journalArticle

narrowband
photonics
crystals
infrared spectrometers
imaging spectrometers

Routine femtogram-level chemical analyses using vibrational spectroscopy and self-cleaning scanning probe microscopy tips

Park, K., Lee, J., Bhargava, R. & King, W. P., May 1 2008, In : Analytical chemistry. 80, 9, p. 3221-3228 8 p.

Research output: Contribution to journalArticle

Scanning probe microscopy
Vibrational spectroscopy
Cleaning
Microscopes
Spectrometry

Route to higher fidelity FT-IR imaging

Bhargava, R., Wang, S. Q. & Koenig, J. L., Apr 2000, In : Applied Spectroscopy. 54, 4, p. 486-495 10 p.

Research output: Contribution to journalArticle

Infrared imaging
Signal to noise ratio
Fourier transforms
routes
signal to noise ratios

Role of collector alternating charged patches on transport of cryptosporidium parvum oocysts in a patchwise charged heterogeneous micromodel

Liu, Y., Zhang, C., Hu, D., Kuhlenschmidt, M. S., Kuhlenschmidt, T. B., Mylon, S. E., Kong, R., Bhargava, R. & Nguyen, T. H., Mar 19 2013, In : Environmental Science and Technology. 47, 6, p. 2670-2678 9 p.

Research output: Contribution to journalArticle

Energy barriers
Microspheres
Silicon Dioxide
silica
energy
Tumor Microenvironment
Confocal Microscopy
Neoplasms

Repairing fractures between data using genetic programming-based feature extraction: A case study in cancer diagnosis

Moreno-Torres, J. G., Llorà, X., Goldberg, D. E. & Bhargava, R., Feb 10 2013, In : Information Sciences. 222, p. 805-823 19 p.

Research output: Contribution to journalArticle

Genetic programming
Genetic Programming
Feature Extraction
Feature extraction
Cancer

Relating strain hardening moduli in high density polyethylene copolymers to anisotropic molecular deformation using infrared spectroscopic imaging

Mukherjee, P., Ghosh, A., Lamborn, M. J., Monwar, M. M., Fodor, J. S., DesLauriers, P. J. & Bhargava, R., May 20 2019, In : Polymer. 172, p. 398-403 6 p.

Research output: Contribution to journalArticle

Polyethylene
High density polyethylenes
Strain hardening
Copolymers
Infrared radiation

Relating Post-yield Mechanical Behavior in Polyethylenes to Spatially Varying Molecular Deformation Using Infrared Spectroscopic Imaging: Homopolymers

Mukherjee, P., Ghosh, A., Spegazzini, N., Lamborn, M. J., Monwar, M. M., Deslauriers, P. J. & Bhargava, R., May 22 2018, In : Macromolecules. 51, 10, p. 3836-3844 9 p.

Research output: Contribution to journalArticle

Polyethylenes
Homopolymerization
Polyethylene
High density polyethylenes
Infrared radiation

Refractive index sensing and surface-enhanced Raman spectroscopy using silver-gold layered bimetallic plasmonic crystals

Kang, S., Lehman, S. E., Schulmerich, M. V., Le, A. P., Lee, T. W., Gray, S. K., Bhargava, R. & Nuzzo, R. G., Jan 1 2017, In : Beilstein Journal of Nanotechnology. 8, 1, p. 2492-2503 12 p.

Research output: Contribution to journalArticle

Silver
Gold
Raman spectroscopy
Refractive index
silver

Recovery of absorption spectra from fourier transform infrared microspectroscopic measurements of intact spheres

Dijk, T. V., Mayerich, D., Scott. Carney, P. & Bhargava, R., Jan 1 2013, Frontiers in Optics, FIO 2013. Optical Society of America, (Optics InfoBase Conference Papers).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Absorption spectra
Identification (control systems)
Fourier transforms
Microscopic examination
recovery

Recovery of absorption spectra from fourier transform infrared (FT-IR) microspectroscopic measurements of intact spheres

Van Dijk, T., Mayerich, D., Carney, P. S. & Bhargava, R., May 1 2013, In : Applied Spectroscopy. 67, 5, p. 546-552 7 p.

Research output: Contribution to journalArticle

Absorption spectra
Fourier transforms
recovery
Infrared radiation
absorption spectra

Reconstructing FT-IR spectroscopic imaging data with a sparse prior

Brady, S. P., Do, M. N. & Bhargava, R., Jan 1 2009, 2009 IEEE International Conference on Image Processing, ICIP 2009 - Proceedings. IEEE Computer Society, p. 829-832 4 p. 5414384. (Proceedings - International Conference on Image Processing, ICIP).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Signal to noise ratio
Fourier transforms
Infrared radiation
Imaging techniques
Compressed sensing

Real-time interactive data mining for chemical imaging information: application to automated histopathology.

Mayerich, D., Walsh, M., Schulmerich, M. & Bhargava, R., 2013, In : Unknown Journal. 14, 1 p.

Research output: Contribution to journalArticle

Data Mining
Data mining
Imaging
Tissue
Real-time

Rapid visualization of macromolecular orientation by discrete frequency mid-infrared spectroscopic imaging

Wrobel, T. P., Mukherjee, P. & Bhargava, R., Jan 7 2017, In : Analyst. 142, 1, p. 75-79 5 p.

Research output: Contribution to journalArticle

Semiconductor Lasers
Fourier Analysis
Molecular Structure
visualization
Microscopy

Rapid spectral domain multiplex localization

Dijk, T. V., Mayerich, D., Bhargava, R. & Scott Carney, P., 2013, Computational Optical Sensing and Imaging, COSI 2013. Optical Society of America

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Nanoprobes
Coherent scattering
coherent scattering
spectral sensitivity
far fields