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Research Output 1998 2019

Label-free biomedical imaging with mid-IR spectroscopy

Walsh, M. J., Reddy, R. K. & Bhargava, R., Jul 23 2012, In : IEEE Journal on Selected Topics in Quantum Electronics. 18, 4, p. 1502-1513 12 p., 6151800.

Research output: Contribution to journalArticle

Labels
Infrared spectroscopy
Infrared imaging
Imaging techniques
spectroscopy

Label-free characterization of cancer-activated fibroblasts using infrared spectroscopic imaging

Holton, S. E., Walsh, M. J., Kajdacsy-Balla, A. & Bhargava, R., Sep 21 2011, In : Biophysical journal. 101, 6, p. 1513-1521 9 p.

Research output: Contribution to journalArticle

Fibroblasts
Coculture Techniques
Neoplasms
Breast
Chemical Evolution

Large infrared absorptance of bimaterial microcantilevers based on silicon high contrast grating

Kwon, B., Seong, M., Liu, J. N., Rosenberger, M. R., Schulmerich, M. V., Bhargava, R., Cunningham, B. T. & King, W. P., Oct 21 2013, In : Journal of Applied Physics. 114, 15, 153511.

Research output: Contribution to journalArticle

absorptance
gratings
silicon
bandwidth
sensitivity

Mapping Solvation Environments in Porous Metal-Organic Frameworks with Infrared Chemical Imaging

Ghosh, A., Mukherjee, P., Deb, S. & Bhargava, R., Nov 2 2017, In : Journal of Physical Chemistry Letters. 8, 21, p. 5325-5330 6 p.

Research output: Contribution to journalArticle

Solvation
solvation
Metals
Infrared radiation
Imaging techniques

Measuring and Predicting the Internal Structure of Semiconductor Nanocrystals through Raman Spectroscopy

Mukherjee, P., Lim, S. J., Wrobel, T. P., Bhargava, R. & Smith, A. M., Aug 31 2016, In : Journal of the American Chemical Society. 138, 34, p. 10887-10896 10 p.

Research output: Contribution to journalArticle

Quantum Dots
Raman Spectrum Analysis
Raman spectroscopy
Nanoparticles
Nanocrystals

Measuring binding kinetics of aromatic thiolated molecules with nanoparticles via surface-enhanced Raman spectroscopy

Devetter, B. M., Mukherjee, P., Murphy, C. J. & Bhargava, R., May 21 2015, In : Nanoscale. 7, 19, p. 8766-8775 10 p.

Research output: Contribution to journalArticle

Raman spectroscopy
Nanoparticles
Gold
Molecules
Kinetics

Mid-infrared microspectroscopic imaging with a Quantum Cascade Laser

Yeh, K., Schulmerich, M. & Bhargava, R., Aug 12 2013, Next-Generation Spectroscopic Technologies VI. 87260E. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 8726).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Quantum cascade lasers
Quantum Cascade Laser
Infrared Imaging
Mid-infrared
Infrared imaging

Mid-infrared thermomechanical sensitivity of microcantilevers for application to infrared spectroscopy

Kwon, B., King, W. P., Schulmerich, M. & Bhargava, R., Dec 1 2010, IEEE Sensors 2010 Conference, SENSORS 2010. p. 2405-2408 4 p. 5691004. (Proceedings of IEEE Sensors).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Infrared spectroscopy
Infrared radiation
Sensors
Monochromators
Spectral resolution

Model-guided design and characterization of a high-precision 3D printing process for carbohydrate glass

Gelber, M. K., Hurst, G., Comi, T. J. & Bhargava, R., Aug 2018, In : Additive Manufacturing. 22, p. 38-50 13 p.

Research output: Contribution to journalArticle

Carbohydrates
Printing
Glass
Nozzles
3D printers

Modeling fourier transform infrared spectroscopic imaging of Prostate and Breast Cancer tissue specimens

Reddy, R., Davis, B., Carney, P. S. & Bhargava, R., Nov 2 2011, 2011 8th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI'11. p. 738-741 4 p. 5872511. (Proceedings - International Symposium on Biomedical Imaging).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fourier Analysis
Prostatic Neoplasms
Fourier transforms
Tissue
Breast Neoplasms

Monolithic multilayer microfluidics via sacrificial molding of 3D-printed isomalt

Gelber, M. K. & Bhargava, R., Apr 7 2015, In : Lab on a chip. 15, 7, p. 1736-1741 6 p.

Research output: Contribution to journalArticle

Microfluidics
Molding
Multilayers
Fungi
3D printers

Multicolor Discrete Frequency Infrared Spectroscopic Imaging

Yeh, K., Lee, D. & Bhargava, R., Feb 5 2019, In : Analytical chemistry. 91, 3, p. 2177-2185 9 p.

Research output: Contribution to journalArticle

Infrared radiation
Scanning
Imaging techniques
Imaging systems
Image quality

Multi-functionality Redefined with Colloidal Carotene Carbon Nanoparticles for Synchronized Chemical Imaging, Enriched Cellular Uptake and Therapy

Misra, S. K., Mukherjee, P., Chang, H. H., Tiwari, S., Gryka, M., Bhargava, R. & Pan, D., Jul 11 2016, In : Scientific reports. 6, 29299.

Research output: Contribution to journalArticle

Carotenoids
Nanoparticles
Carbon
Ligands
Phospholipids

Multimodal Chemical Analysis of the Brain by High Mass Resolution Mass Spectrometry and Infrared Spectroscopic Imaging

Neumann, E. K., Comi, T. J., Spegazzini, N., Mitchell, J. W., Rubakhin, S. S., Gillette, M. U., Bhargava, R. & Sweedler, J. V., Oct 2 2018, In : Analytical chemistry. 90, 19, p. 11572-11580 9 p.

Research output: Contribution to journalArticle

Mass spectrometry
Brain
Infrared radiation
Imaging techniques
Chemical analysis

Multimodal microscopy for automated histologic analysis of prostate cancer

Kwak, J. T., Hewitt, S. M., Sinha, S. & Bhargava, R., Feb 9 2011, In : BMC Cancer. 11, 62.

Research output: Contribution to journalArticle

Microscopy
Prostatic Neoplasms
ROC Curve
Area Under Curve
Biopsy

Nanoscale imaging of biological samples with responsivity corrected atomic force microscopy-infrared (AFM-IR) spectroscopy

Kenkel, S. & Bhargava, R., Jan 1 2019, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVI. Nicolau, D. V., Fixler, D. & Goldys, E. M. (eds.). SPIE, 108910A. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10891).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Atomic Force Microscopy
Infrared spectroscopy
Atomic force microscopy
Spectrum Analysis
infrared spectroscopy

Narrowband guided fano resonators for mid-infrared spectroscopy and imaging

Liu, J. N., Schulmerich, M. V., Bhargava, R. & Cunningham, B. T., 2014, CLEO: Applications and Technology, CLEO_AT 2014. Optical Society of American (OSA)

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Infrared imaging
Stretching
narrowband
Resonators
Infrared spectroscopy

Narrowband guided fano resonators for mid-infrared spectroscopy and imaging

Liu, J. N., Schulmerich, M. V., Bhargava, R. & Cunningham, B. T., 2014, 2014 Conference on Lasers and Electro-Optics, CLEO 2014. Institute of Electrical and Electronics Engineers Inc., Vol. 2014-January. 6988364

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Infrared imaging
Stretching
narrowband
Resonators
Infrared spectroscopy

Narrowband midinfrared reflectance filters using guided mode resonance

Kodali, A. K., Schulmerich, M., Ip, J., Yen, G., Cunningham, B. T. & Bhargava, R., Jul 1 2010, In : Analytical chemistry. 82, 13, p. 5697-5706 10 p.

Research output: Contribution to journalArticle

Spectrum Analysis
Infrared radiation
Infrared spectrometers
Infrared absorption
Absorption spectroscopy

Non-invasive detection of superimposed latent fingerprints and inter-ridge trace evidence by infrared spectroscopic imaging

Bhargava, R., Schwartz Perlman, R., Fernandez, D. C., Levin, I. W. & Bartick, E. G., Aug 1 2009, In : Analytical and Bioanalytical Chemistry. 394, 8, p. 2069-2075 7 p.

Research output: Contribution to journalArticle

Dermatoglyphics
Infrared radiation
Imaging techniques
Crime
Chemical analysis

Noninvasive imaging of molecular dynamics in heterogeneous materials

Bhargava, R. & Levin, I. W., Jan 14 2003, In : Macromolecules. 36, 1, p. 92-96 5 p.

Research output: Contribution to journalArticle

Liquid crystal polymers
Molecular dynamics
Imaging techniques
Liquid crystals
Liquid Crystals

Novel route to faster Fourier transform infrared spectroscopic imaging

Bhargava, R., Schaeberle, M. D., Fernandez, D. C. & Levin, I. W., Aug 1 2001, In : Applied Spectroscopy. 55, 8, p. 1079-1084 6 p.

Research output: Contribution to journalArticle

Fast Fourier transforms
signal to noise ratios
routes
Infrared radiation
Imaging techniques

Observation of molecular diffusion in polyelectrolyte-wrapped SERS nanoprobes

Devetter, B. M., Sivapalan, S. T., Patel, D. D., Schulmerich, M. V., Murphy, C. J. & Bhargava, R., Jul 29 2014, In : Langmuir. 30, 29, p. 8931-8937 7 p.

Research output: Contribution to journalArticle

Nanoprobes
molecular diffusion
Polyelectrolytes
Raman spectroscopy
Methylene Blue

Observer-invariant histopathology using genetics-based machine learning

Llorà, X., Priya, A. & Bhargava, R., Jan 1 2009, In : Natural Computing. 8, 1, p. 101-120 20 p.

Research output: Contribution to journalArticle

Learning systems
Tissue
Medical image processing
Imaging techniques
Computer aided diagnosis

Off-resonance surface-enhanced raman spectroscopy from gold nanorod suspensions as a function of aspect ratio: Not what we thought

Sivapalan, S. T., Devetter, B. M., Yang, T. K., Van Dijk, T., Schulmerich, M. V., Carney, P. S., Bhargava, R. & Murphy, C. J., Mar 26 2013, In : ACS Nano. 7, 3, p. 2099-2105 7 p.

Research output: Contribution to journalArticle

Nanorods
Gold
nanorods
Raman spectroscopy
aspect ratio

On the homogenization of data from two laboratories using Genetic Programming

Moreno-Torres, J. G., Llorà, X., Goldberg, D. E. & Bhargava, R., Dec 1 2010, Learning Classifier Systems - 11th International Workshop, IWLCS 2008 and 12th International Workshop, IWLCS 2009, Revised Selected Papers. p. 185-197 13 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 6471 LNAI).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Genetic programming
Genetic Programming
Homogenization
Classifiers
Network protocols

On the importance of image formation optics in the design of infrared spectroscopic imaging systems

Mayerich, D., Van Dijk, T., Walsh, M. J., Schulmerich, M. V., Carney, P. S. & Bhargava, R., Jul 14 2014, In : Analyst. 139, 16, p. 4031-4036 6 p.

Research output: Contribution to journalArticle

Imaging systems
Optics
Image processing
Infrared radiation
Microscopes
Metals
Nanospheres
Molecular Probes
Raman Spectrum Analysis
Electromagnetic Phenomena

Optimally designed narrowband guided-mode resonance reflectance filters for mid-infrared spectroscopy

Liu, J. N., Schulmerich, M. V., Bhargava, R. & Cunningham, B. T., Nov 21 2011, In : Optics Express. 19, 24, p. 24182-24197 16 p.

Research output: Contribution to journalArticle

narrowband
infrared spectroscopy
reflectance
filters
bandwidth

Optimization of the Raman signal in suspensions of nanoparticle aggregates

Dijk, T. V., Bhargava, R. & Scott Carney, P., Jan 1 2013, Frontiers in Optics, FIO 2013. Optical Society of America, (Optics InfoBase Conference Papers).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Light extinction
Raman scattering
Nanoparticles
nanoparticles
optimization

Optimized nanospherical layered alternating metal-dielectric probes for optical sensing

Kodali, A. K., Schulmerich, M. V., Palekar, R., Llora, X. & Bhargava, R., Oct 25 2010, In : Optics Express. 18, 22, p. 23302-23313 12 p.

Research output: Contribution to journalArticle

probes
silicon dioxide
metals
Mie scattering
spectral sensitivity

Optimizing the design of FT-IR spectroscopic imaging instruments to obtain increased spatial resolution of chemical species

Reddy, R., Mayerich, D., Walsh, M., Schulmerich, M., Carney, P. S. & Bhargava, R., Aug 15 2012, 2012 9th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2012 - Proceedings. p. 354-357 4 p. 6235557. (Proceedings - International Symposium on Biomedical Imaging).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fourier Analysis
Fourier transforms
Imaging systems
Tissue
Infrared radiation

Overcoming difficulties in research statement preparation for the academic job search: Expansion of a peer-focused professional development program

Tyler, K. I., Li, Y., Jackson, N. D., Chen, W. T., Liu, C. & Bhargava, R., Jun 24 2017, In : ASEE Annual Conference and Exposition, Conference Proceedings. 2017-June

Research output: Contribution to journalConference article

Technical presentations
Students

Pixelated spatial gene expression analysis from tissue

Ganguli, A., Ornob, A., Spegazzini, N., Liu, Y., Damhorst, G., Ghonge, T., Thornton, B., Konopka, C. J., Dobrucki, W., Clare, S. E., Bhargava, R., Smith, A. M., Kosari, F. & Bashir, R., Dec 1 2018, In : Nature communications. 9, 1, 202.

Research output: Contribution to journalArticle

gene expression
Gene expression
Tissue
Gene Expression
ribonucleic acids

Plasmon-enhanced upconversion: Engineering enhancement and quenching at nano and macro scales

Rasskazov, I. L., Wang, L., Murphy, C. J., Bhargava, R. & Carney, P. S., Jan 1 2018, In : Optical Materials Express. 8, 12, p. 3787-3804 18 p.

Research output: Contribution to journalArticle

Metal nanoparticles
Macros
Quenching
Photons
Electromagnetic fields

Polymeric microfluidic continuous flow mixer combined with hyperspectral FT-IR imaging for studying rapid biomolecular events

Jang, H., Pawate, A. S., Bhargava, R. & Kenis, P. J. A., Jan 1 2019, In : Lab on a chip. 19, 15, p. 2598-2609 12 p.

Research output: Contribution to journalArticle

Microfluidics
Protein Folding
Infrared imaging
Fourier Analysis
Cycloparaffins

Practical protocols for fast histopathology by Fourier transform infrared spectroscopic imaging

Keith, F. N., Reddy, R. K. & Bhargava, R., Apr 21 2008, Biomedical Optical Spectroscopy. 685306. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 6853).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fourier transforms
Tissue
Infrared radiation
Imaging techniques
Michelson interferometers

Preface

Bhargava, R. & Levin, I. W., Nov 12 2007, In : Spectrochemical Analysis Using Infrared Multichannel Detectors.

Research output: Contribution to journalArticle

Preface

Bhargava, R., May 26 2009, In : Vibrational Spectroscopy. 50, 1, 1 p.

Research output: Contribution to journalEditorial

Preparing female engineering doctoral students for the Academic Job Market through a training program inspired by peer review

Li, Y., Mai, D. J., Horstman, E. & Bhargava, R., 2015, 122nd ASEE Annual Conference and Exposition: Making Value for Society. American Society for Engineering Education

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Students

Probe-Sample Interaction-Independent Atomic Force Microscopy-Infrared Spectroscopy: Toward Robust Nanoscale Compositional Mapping

Kenkel, S., Mittal, A., Mittal, S. & Bhargava, R., Aug 7 2018, In : Analytical chemistry. 90, 15, p. 8845-8855 11 p.

Research output: Contribution to journalArticle

Infrared spectroscopy
Atomic force microscopy
Infrared radiation
Imaging techniques
Infrared imaging

Probing structure and dynamics in liquid crystalline microdomains by infrared spectroscopy

Bhargava, R. & Levin, I. W., Jan 16 2004, In : Vibrational Spectroscopy. 34, 1, p. 13-24 12 p.

Research output: Contribution to journalArticle

Liquid Crystals
Infrared spectroscopy
Crystalline materials
Liquids
Composite materials

Processing FT-IR imaging data for morphology visualization

Bhargava, R., Wang, S. Q. & Koenig, J. L., Nov 1 2000, In : Applied Spectroscopy. 54, 11, p. 1690-1706 17 p.

Research output: Contribution to journalArticle

Infrared imaging
Fourier transforms
Visualization
Display devices
Processing

Protein and oil composition predictions of single soybeans by transmission Raman spectroscopy

Schulmerich, M. V., Walsh, M. J., Gelber, M. K., Kong, R., Kole, M. R., Harrison, S. K., McKinney, J., Thompson, D., Kull, L. S. & Bhargava, R., Aug 22 2012, In : Journal of Agricultural and Food Chemistry. 60, 33, p. 8097-8102 6 p.

Research output: Contribution to journalArticle

Raman spectroscopy
Raman Spectrum Analysis
Soybeans
Oils
soybeans

PSIP1/p75 promotes tumorigenicity in breast cancer cells by promoting the transcription of cell cycle genes

Singh, D. K., Gholamalamdari, O., Jadaliha, M., Li, X. L., Lin, Y. C., Zhang, Y., Guang, S., Hashemikhabir, S., Tiwari, S., Zhu, Y. J., Khan, A., Thomas, A., Chakraborty, A., Macias, V., Balla, A. K., Bhargava, R., Janga, S. C., Ma, J., Prasanth, S. G., Lal, A. & 1 others, Kannanganattu, P. K., Oct 1 2017, In : Carcinogenesis. 38, 10, p. 966-975 10 p., bgx062.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
cdc Genes
Breast Neoplasms
RNA Polymerase II
Cell Line

Quantifying collagen structure in breast biopsies using second-harmonic generation imaging

Ambekar, R., Lau, T. Y., Walsh, M., Bhargava, R. & Toussaint, K. C., Sep 1 2012, In : Biomedical Optics Express. 3, 9, p. 2021-2035 15 p.

Research output: Contribution to journalArticle

collagens
breast
harmonic generations
Breast
Collagen

Quantitative Chemical Imaging of Nonplanar Microfluidics

Gelber, M. K., Kole, M. R., Kim, N., Aluru, N. R. & Bhargava, R., Feb 7 2017, In : Analytical chemistry. 89, 3, p. 1716-1723 8 p.

Research output: Contribution to journalArticle

Microfluidics
Stimulated Raman scattering
Imaging techniques
Aberrations
Refractive index

Quantitative microscopic evaluation of mucin areas and its percentage in mucinous carcinoma of the breast using tissue histological images

Saha, M., Arun, I., Basak, B., Agarwal, S., Ahmed, R., Chatterjee, S., Bhargava, R. & Chakraborty, C., Jun 1 2016, In : Tissue and Cell. 48, 3, p. 265-273 9 p.

Research output: Contribution to journalArticle

Mucinous Adenocarcinoma
Mucins
Breast
Color
Carcinoma, Ductal, Breast

Rapid spectral-domain localization

Van Dijk, T., Mayerich, D., Bhargava, R. & Scott Carney, P., May 20 2013, In : Optics Express. 21, 10, p. 12822-12830 9 p.

Research output: Contribution to journalArticle

spatial resolution
coherent scattering
probes
spectral sensitivity
data acquisition

Rapid spectral domain multiplex localization

Dijk, T. V., Mayerich, D., Bhargava, R. & Scott Carney, P., 2013, Computational Optical Sensing and Imaging, COSI 2013. Optical Society of America

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Nanoprobes
Coherent scattering
coherent scattering
spectral sensitivity
far fields