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Rohit Bhargava

19982019
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Research Output 1998 2019

2019

A comparison of mid-infrared spectral regions on accuracy of tissue classification

Mittal, S. & Bhargava, R., Apr 21 2019, In : Analyst. 144, 8, p. 2635-2642 8 p.

Research output: Contribution to journal › Article

Dermatoglyphics
Tissue
Infrared radiation
Pixels
Breast

A fully automated, faster noise rejection approach to increasing the analytical capability of chemical imaging for digital histopathology

Gupta, S., Mittal, S., Kajdacsy-Balla, A., Bhargava, R. & Bajaj, C., Apr 2019, In : PloS one. 14, 4, e0205219.

Research output: Contribution to journal › Article

Open Access
histopathology
Noise
image analysis
Imaging techniques
Signal to noise ratio

Bulk Protein and Oil Prediction in Soybeans Using Transmission Raman Spectroscopy: A Comparison of Approaches to Optimize Accuracy

Singh, R., Wrobel, T. P., Mukherjee, P., Gryka, M., Kole, M., Harrison, S. & Bhargava, R., Jun 1 2019, In : Applied Spectroscopy. 73, 6, p. 687-697 11 p.

Research output: Contribution to journal › Article

soybeans
Raman spectroscopy
Oils
oils
proteins

Controlled dissolution of freeform 3D printed carbohydrate glass scaffolds in hydrogels using a hydrophobic spray coating

Gryka, M. C., Comi, T. J., Forsyth, R. A., Hadley, P. M., Deb, S. & Bhargava, R., Mar 2019, In : Additive Manufacturing. 26, p. 193-201 9 p.

Research output: Contribution to journal › Article

Hydrogels
Carbohydrates
Scaffolds
Dissolution
Glass

Deep learning for FTIR histology: leveraging spatial and spectral features with convolutional neural networks

Berisha, S., Lotfollahi, M., Jahanipour, J., Gurcan, I., Walsh, M., Bhargava, R., Van Nguyen, H. & Mayerich, D., Mar 7 2019, In : Analyst. 144, 5, p. 1642-1653 12 p.

Research output: Contribution to journal › Article

Histology
histology
Fourier Analysis
Fourier transform
Fourier transforms

Digital Assessment of Stained Breast Tissue Images for Comprehensive Tumor and Microenvironment Analysis

Mittal, S., Stoean, C., Kajdacsy-Balla, A. & Bhargava, R., Oct 1 2019, In : Frontiers in Bioengineering and Biotechnology. 7, 246.

Research output: Contribution to journal › Article

Open Access
Tumor Microenvironment
Tumors
Breast
Epithelial Cells
Tissue

Enzyme-catalysed biodegradation of carbon dots follows sequential oxidation in a time dependent manner

Srivastava, I., Sar, D., Mukherjee, P., Schwartz-Duval, A. S., Huang, Z., Jaramillo, C., Civantos, A., Tripathi, I., Allain, J. P., Bhargava, R. & Pan, D., May 7 2019, In : Nanoscale. 11, 17, p. 8226-8236 11 p.

Research output: Contribution to journal › Article

Biodegradation
Carbon
Enzymes
Oxidation
Degradation

Extended Multiplicative Signal Correction for Infrared Microspectroscopy of Heterogeneous Samples with Cylindrical Domains

Rasskazov, I. L., Singh, R., Carney, P. S. & Bhargava, R., Aug 1 2019, In : Applied Spectroscopy. 73, 8, p. 859-869 11 p.

Research output: Contribution to journal › Article

Scattering
Infrared radiation
Mie scattering
scattering
Fibers

Freeform Assembly Planning

Gelber, M. K., Hurst, G. & Bhargava, R., Jul 2019, In : IEEE Transactions on Automation Science and Engineering. 16, 3, p. 1315-1329 15 p., 8554172.

Research output: Contribution to journal › Article

Printing
Planning
3D printers
D region
Functional materials

Multicolor Discrete Frequency Infrared Spectroscopic Imaging

Yeh, K., Lee, D. & Bhargava, R., Feb 5 2019, In : Analytical chemistry. 91, 3, p. 2177-2185 9 p.

Research output: Contribution to journal › Article

Infrared radiation
Scanning
Imaging techniques
Imaging systems
Image quality

Nanoscale imaging of biological samples with responsivity corrected atomic force microscopy-infrared (AFM-IR) spectroscopy

Kenkel, S. & Bhargava, R., Jan 1 2019, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVI. Nicolau, D. V., Fixler, D. & Goldys, E. M. (eds.). SPIE, 108910A. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10891).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Atomic Force Microscopy
Infrared spectroscopy
Atomic force microscopy
Spectrum Analysis
infrared spectroscopy

Polymeric microfluidic continuous flow mixer combined with hyperspectral FT-IR imaging for studying rapid biomolecular events

Jang, H., Pawate, A. S., Bhargava, R. & Kenis, P. J. A., Jan 1 2019, In : Lab on a chip. 19, 15, p. 2598-2609 12 p.

Research output: Contribution to journal › Article

Microfluidics
Protein Folding
Infrared imaging
Fourier Analysis
Cycloparaffins

Relating strain hardening moduli in high density polyethylene copolymers to anisotropic molecular deformation using infrared spectroscopic imaging

Mukherjee, P., Ghosh, A., Lamborn, M. J., Monwar, M. M., Fodor, J. S., DesLauriers, P. J. & Bhargava, R., May 20 2019, In : Polymer. 172, p. 398-403 6 p.

Research output: Contribution to journal › Article

Polyethylene
High density polyethylenes
Strain hardening
Copolymers
Infrared radiation

Reply to Paraskevaidi et al. Epithelial and microenvironment characterization is key to understanding and improving diagnoses

Yeh, K., Mittal, S. & Bhargava, R., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 11, p. 4753-4754 2 p.

Research output: Contribution to journal › Letter

Tumor Microenvironment
Confocal Microscopy
Neoplasms
2018

Agile optoelectronic fiber sources for hyperspectral chemical sensing from SWIR to LWIR

Kang, I., Grant, A., Dinu, M., Jaques, J., Pfister, L., Bhargava, R. & Carney, P. S., Jan 1 2018, Algorithms and Technologies for Multispectral, Hyperspectral, and Ultraspectral Imagery XXIV. Messinger, D. W. & Velez-Reyes, M. (eds.). SPIE, 106441E. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 10644).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Optoelectronics
Optoelectronic devices
Sensing
Infrared
Fiber

A natural antisense lncRNA controls breast cancer progression by promoting tumor suppressor gene mRNA stability

Jadaliha, M., Gholamalamdari, O., Tang, W., Zhang, Y., Petracovici, A., Hao, Q., Tariq, A., Kim, T. G., Holton, S. E., Singh, D. K., Li, X. L., Freier, S. M., Ambs, S., Bhargava, R., Lal, A., Prasanth, S. G., Ma, J. & Prasanth, K. V., Nov 2018, In : PLoS genetics. 14, 11, e1007802.

Research output: Contribution to journal › Article

Long Noncoding RNA
tumor suppressor genes
RNA Stability
Tumor Suppressor Genes
tumor

Application of Vibrational Spectroscopy and Imaging to Point-of-Care Medicine: A Review

Pahlow, S., Weber, K., Popp, J., Wood, B. R., Kochan, K., Rüther, A., Perez-Guaita, D., Heraud, P., Stone, N., Dudgeon, A., Gardner, B., Reddy, R., Mayerich, D. & Bhargava, R., Sep 1 2018, In : Applied Spectroscopy. 72, 1_suppl, p. 52-84 33 p.

Research output: Contribution to journal › Article

Point-of-Care Systems
Single-Cell Analysis
Intraoperative Monitoring
Vibrational spectroscopy
urine

FT-IR- and Raman-based biochemical profiling of the early stage of pulmonary metastasis of breast cancer in mice

Chrabaszcz, K., Kochan, K., Fedorowicz, A., Jasztal, A., Buczek, E., Leslie, L. S., Bhargava, R., Malek, K., Chlopicki, S. & Marzec, K. M., May 7 2018, In : Analyst. 143, 9, p. 2042-2050 9 p.

Research output: Contribution to journal › Article

Raman spectroscopy
Glycogen
Lipids
cancer
lipid

Infrared Spectroscopic Imaging Advances as an Analytical Technology for Biomedical Sciences

Wrobel, T. P. & Bhargava, R., Feb 6 2018, In : Analytical chemistry. 90, 3, p. 1444-1463 20 p.

Research output: Contribution to journal › Review article

Infrared Spectrophotometry
Biomedical Technology
Biomedical Research
Light

Model-guided design and characterization of a high-precision 3D printing process for carbohydrate glass

Gelber, M. K., Hurst, G., Comi, T. J. & Bhargava, R., Aug 2018, In : Additive Manufacturing. 22, p. 38-50 13 p.

Research output: Contribution to journal › Article

Carbohydrates
Printing
Glass
Nozzles
3D printers

Multimodal Chemical Analysis of the Brain by High Mass Resolution Mass Spectrometry and Infrared Spectroscopic Imaging

Neumann, E. K., Comi, T. J., Spegazzini, N., Mitchell, J. W., Rubakhin, S. S., Gillette, M. U., Bhargava, R. & Sweedler, J. V., Oct 2 2018, In : Analytical chemistry. 90, 19, p. 11572-11580 9 p.

Research output: Contribution to journal › Article

Mass spectrometry
Brain
Infrared radiation
Imaging techniques
Chemical analysis

Pixelated spatial gene expression analysis from tissue

Ganguli, A., Ornob, A., Spegazzini, N., Liu, Y., Damhorst, G., Ghonge, T., Thornton, B., Konopka, C. J., Dobrucki, W., Clare, S. E., Bhargava, R., Smith, A. M., Kosari, F. & Bashir, R., Dec 1 2018, In : Nature communications. 9, 1, 202.

Research output: Contribution to journal › Article

gene expression
Gene expression
Tissue
Gene Expression
ribonucleic acids

Plasmon-enhanced upconversion: Engineering enhancement and quenching at nano and macro scales

Rasskazov, I. L., Wang, L., Murphy, C. J., Bhargava, R. & Carney, P. S., Jan 1 2018, In : Optical Materials Express. 8, 12, p. 3787-3804 18 p.

Research output: Contribution to journal › Article

Metal nanoparticles
Macros
Quenching
Photons
Electromagnetic fields

Probe-Sample Interaction-Independent Atomic Force Microscopy-Infrared Spectroscopy: Toward Robust Nanoscale Compositional Mapping

Kenkel, S., Mittal, A., Mittal, S. & Bhargava, R., Aug 7 2018, In : Analytical chemistry. 90, 15, p. 8845-8855 11 p.

Research output: Contribution to journal › Article

Infrared spectroscopy
Atomic force microscopy
Infrared radiation
Imaging techniques
Infrared imaging

Relating Post-yield Mechanical Behavior in Polyethylenes to Spatially Varying Molecular Deformation Using Infrared Spectroscopic Imaging: Homopolymers

Mukherjee, P., Ghosh, A., Spegazzini, N., Lamborn, M. J., Monwar, M. M., Deslauriers, P. J. & Bhargava, R., May 22 2018, In : Macromolecules. 51, 10, p. 3836-3844 9 p.

Research output: Contribution to journal › Article

Polyethylenes
Homopolymerization
Polyethylene
High density polyethylenes
Infrared radiation

Selecting optimal features from Fourier transform infrared spectroscopy for discrete-frequency imaging

Mankar, R., Walsh, M. J., Bhargava, R., Prasad, S. & Mayerich, D., Mar 7 2018, In : Analyst. 143, 5, p. 1147-1156 10 p.

Research output: Contribution to journal › Article

Histology
histology
Fourier Transform Infrared Spectroscopy
FTIR spectroscopy
Fourier transform infrared spectroscopy

Simultaneous cancer and tumor microenvironment subtyping using confocal infrared microscopy for all-digital molecular histopathology

Mittal, S., Yeh, K., Suzanne Leslie, L., Kenkel, S., Kajdacsy-Balla, A. & Bhargava, R., Jun 19 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 25, p. E5651-E5660

Research output: Contribution to journal › Article

Tumor Microenvironment
Confocal Microscopy
Breast
Epithelial Cells
Research
2017

BIM-Sim: Interactive simulation of broadband imaging using mie theory

Berisha, S., van Dijk, T., Bhargava, R., Carney, P. S. & Mayerich, D., Feb 20 2017, In : Frontiers in Physics. 5, FEB, 5.

Research output: Contribution to journal › Article

Mie Theory
Interactive Simulation
Electromagnetic Fields
Mie scattering
Electromagnetic fields

Characterization of the structure of low-e substrates and consequences for IR transflection measurements

DeVetter, B. M., Kenkel, S., Mittal, S., Bhargava, R. & Wrobel, T. P., Jul 2017, In : Vibrational Spectroscopy. 91, p. 119-127 9 p.

Research output: Contribution to journal › Article

Infrared radiation
Substrates
Gold
Infrared spectroscopy
Glass

Dielectric Sphere Clusters as a Model to Understand Infrared Spectroscopic Imaging Data Recorded from Complex Samples

Rasskazov, I. L., Spegazzini, N., Carney, P. S. & Bhargava, R., Oct 17 2017, In : Analytical chemistry. 89, 20, p. 10813-10818 6 p.

Research output: Contribution to journal › Article

Infrared radiation
Imaging techniques
Polymethyl Methacrylate
Scattering
Multiple scattering

Keeping current: An update on the structure and evaluation of a program for graduate women interested in engineering Academia

Jackson, N. D., Tyler, K. I., Li, Y., Chen, W. T., Liu, C. & Bhargava, R., Jun 24 2017, In : ASEE Annual Conference and Exposition, Conference Proceedings. 2017-June

Research output: Contribution to journal › Conference article

Students
Feedback
Technical presentations
Pipelines
Engineers

Mapping Solvation Environments in Porous Metal-Organic Frameworks with Infrared Chemical Imaging

Ghosh, A., Mukherjee, P., Deb, S. & Bhargava, R., Nov 2 2017, In : Journal of Physical Chemistry Letters. 8, 21, p. 5325-5330 6 p.

Research output: Contribution to journal › Article

Solvation
solvation
Metals
Infrared radiation
Imaging techniques

Overcoming difficulties in research statement preparation for the academic job search: Expansion of a peer-focused professional development program

Tyler, K. I., Li, Y., Jackson, N. D., Chen, W. T., Liu, C. & Bhargava, R., Jun 24 2017, In : ASEE Annual Conference and Exposition, Conference Proceedings. 2017-June

Research output: Contribution to journal › Conference article

Technical presentations
Students

PSIP1/p75 promotes tumorigenicity in breast cancer cells by promoting the transcription of cell cycle genes

Singh, D. K., Gholamalamdari, O., Jadaliha, M., Li, X. L., Lin, Y. C., Zhang, Y., Guang, S., Hashemikhabir, S., Tiwari, S., Zhu, Y. J., Khan, A., Thomas, A., Chakraborty, A., Macias, V., Balla, A. K., Bhargava, R., Janga, S. C., Ma, J., Prasanth, S. G., Lal, A. & 1 others, Kannanganattu, P. K., Oct 1 2017, In : Carcinogenesis. 38, 10, p. 966-975 10 p., bgx062.

Research output: Contribution to journal › Article

Triple Negative Breast Neoplasms
cdc Genes
Breast Neoplasms
RNA Polymerase II
Cell Line

Quantitative Chemical Imaging of Nonplanar Microfluidics

Gelber, M. K., Kole, M. R., Kim, N., Aluru, N. R. & Bhargava, R., Feb 7 2017, In : Analytical chemistry. 89, 3, p. 1716-1723 8 p.

Research output: Contribution to journal › Article

Microfluidics
Stimulated Raman scattering
Imaging techniques
Aberrations
Refractive index

Rapid visualization of macromolecular orientation by discrete frequency mid-infrared spectroscopic imaging

Wrobel, T. P., Mukherjee, P. & Bhargava, R., Jan 7 2017, In : Analyst. 142, 1, p. 75-79 5 p.

Research output: Contribution to journal › Article

Semiconductor Lasers
Fourier Analysis
Molecular Structure
visualization
Microscopy

Refractive index sensing and surface-enhanced Raman spectroscopy using silver-gold layered bimetallic plasmonic crystals

Kang, S., Lehman, S. E., Schulmerich, M. V., Le, A. P., Lee, T. W., Gray, S. K., Bhargava, R. & Nuzzo, R. G., Jan 1 2017, In : Beilstein Journal of Nanotechnology. 8, 1, p. 2492-2503 12 p.

Research output: Contribution to journal › Article

Silver
Gold
Raman spectroscopy
Refractive index
silver

The Chemistry of Thought: The Role of the Measurement Sciences in Brain Research

Andrews, A. M., Bhargava, R., Kennedy, R., Li, L. & Sweedler, J. V., May 2 2017, In : Analytical chemistry. 89, 9, 1 p.

Research output: Contribution to journal › Editorial

2016

A four class model for digital breast histopathology using high-definition Fourier transform infrared (FT-IR) spectroscopic imaging

Mittal, S., Wrobel, T. P., Leslie, L. S., Kadjacsy-Balla, A. & Bhargava, R., Jan 1 2016, Medical Imaging 2016: Digital Pathology. Madabhushi, A. & Gurcan, M. N. (eds.). SPIE, 979118. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 9791).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Fourier Analysis
breast
Fourier transforms
Breast
pathology

Automated prostate tissue referencing for cancer detection and diagnosis

Kwak, J. T., Hewitt, S. M., Kajdacsy-Balla, A. A., Sinha, S. & Bhargava, R., Jun 1 2016, In : BMC bioinformatics. 17, 1, 227.

Research output: Contribution to journal › Article

Prostate
Cancer
Tissue
Neoplasms
Retrieval

Characterization of core-shell microstructure and self-healing performance of electrospun fiber coatings

Doan, T. Q., Leslie, L. S., Kim, S. Y., Bhargava, R., White, S. R. & Sottos, N. R., Dec 19 2016, In : Polymer. 107, p. 263-272 10 p.

Research output: Contribution to journal › Article

Coatings
Microstructure
Fibers
Crosslinking
Corrosion

Clinical Spectroscopy: General discussion

Goodacre, R., Sergo, V., Barr, H., Sammon, C., Schultz, Z. D., Baker, M. J., Graham, D., Marques, M. P., Sulé-Suso, J., Livermore, J., Faulds, K., Sinjab, F., Matousek, P., Campbell, C. J., Dluhy, R., Gardner, P., Phillips, C., Diem, M., Wood, B., Apolonskiy, A. & 21 others, Kazarian, S., Fullwood, L., Gough, K., Petrich, W., Lloyd, G., Ibrahim, O., Cinque, G., Sockalingum, G. D., Stone, N., Kendall, C., McAughtrie, S., Perez-Guaita, D., Clark, L., Gerwert, K., Bonifacio, A., Notingher, I., Lasch, P., Bhargava, R., Lepert, G., Mader, K. & Paterson, C., Jan 1 2016, In : Faraday Discussions. 187, p. 429-460 32 p.

Research output: Contribution to journal › Article

Diagnostic Imaging
Spectrum Analysis

Defined Host–Guest Chemistry on Nanocarbon for Sustained Inhibition of Cancer

Ostadhossein, F., Misra, S. K., Mukherjee, P., Ostadhossein, A., Daza, E., Tiwari, S., Mittal, S., Gryka, M. C., Bhargava, R. & Pan, D., Nov 9 2016, In : Small. 12, 42, p. 5845-5861 17 p.

Research output: Contribution to journal › Article

Transcription Factor 3
STAT3 Transcription Factor
Transcription factors
Niclosamide
Transducers

Development of a practical spatial-spectral analysis protocol for breast histopathology using Fourier transform infrared spectroscopic imaging

Pounder, F. N., Reddy, R. K. & Bhargava, R., Jan 1 2016, In : Faraday Discussions. 187, p. 43-68 26 p.

Research output: Contribution to journal › Article

breast
Spectrum analysis
spectrum analysis
Tumors
Fourier transforms

Discrete frequency infrared imaging using quantum cascade lasers for biological tissue analysis

Yeh, K. & Bhargava, R., Jan 1 2016, Biomedical Vibrational Spectroscopy 2016: Advances in Research and Industry. Mahadevan-Jansen, A. & Petrich, W. (eds.). SPIE, 970406. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 9704).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Semiconductor Lasers
Quantum cascade lasers
Infrared imaging
quantum cascade lasers
Tissue

Emerging Themes in Image Informatics and Molecular Analysis for Digital Pathology

Bhargava, R. & Madabhushi, A., Jul 11 2016, In : Annual Review of Biomedical Engineering. 18, p. 387-412 26 p.

Research output: Contribution to journal › Article

Informatics
Pathology
Precision Medicine
Molecular Pathology
Telepathology

Emerging trends and opportunities in discrete-frequency infrared and Raman spectroscopic imaging

Wrobel, T. P., Kole, M. R. & Bhargava, R., Jun 2016, In : Spectroscopy (Santa Monica). 31, 6

Research output: Contribution to journal › Review article

emerging
Microscopic examination
microscopy
Infrared radiation
trends

High-definition Fourier transform infrared spectroscopic imaging of prostate tissue

Wrobel, T. P., Kwak, J. T., Kadjacsy-Balla, A. & Bhargava, R., Jan 1 2016, Medical Imaging 2016: Digital Pathology. Madabhushi, A. & Gurcan, M. N. (eds.). SPIE, 97911D. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 9791).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Dermatoglyphics
pathology
Pathology
Fourier Analysis
Prostate

Implementing a challenge-inspired undergraduate experience

Pool, M., Bhargava, R., Carney, P. S., Pan, D. & Smith, A. M., Jun 26 2016, 2016 ASEE Annual Conference and Exposition. American Society for Engineering Education, Vol. 2016-June.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Infrared emission spectroscopy of atmospheric-pressure ball plasmoids

Dubowsky, S. E., Deutsch, B., Bhargava, R. & McCall, B. J., Apr 1 2016, In : Journal of Molecular Spectroscopy. 322, p. 1-8 8 p.

Research output: Contribution to journal › Article

Emission spectroscopy
Atmospheric pressure
balls
Infrared spectroscopy
atmospheric pressure