19952019
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Research Output 1995 2019

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Review article
2006

Chemical countermeasures for the control of bacterial biofilms: Effective compounds and promising targets

Musk, D. J. & Hergenrother, P. J., Jul 1 2006, In : Current Medicinal Chemistry. 13, 18, p. 2163-2177 15 p.

Research output: Contribution to journalReview article

Biofilms
Quorum Sensing
Infection
Bacterial Infections
Bacteria

Obtaining and screening compound collections: a user's guide and a call to chemists

Hergenrother, P., Jun 1 2006, In : Current Opinion in Chemical Biology. 10, 3, p. 213-218 6 p.

Research output: Contribution to journalReview article

Screening
Ligands
Throughput
Cytology
Proteomics
2007

DNA as a target for anticancer compounds: methods to determine the mode of binding and the mechanism of action

Palchaudhuri, R. & Hergenrother, P., Dec 1 2007, In : Current Opinion in Biotechnology. 18, 6, p. 497-503 7 p.

Research output: Contribution to journalReview article

DNA
Assays
Molecules
Intercalation
Pharmaceutical Preparations

Poly(ADP-ribose) makes a date with death

Heeres, J. T. & Hergenrother, P., Dec 1 2007, In : Current Opinion in Chemical Biology. 11, 6, p. 644-653 10 p.

Research output: Contribution to journalReview article

Apoptosis Inducing Factor
Poly Adenosine Diphosphate Ribose
Mitochondria
Poly(ADP-ribose) Polymerases
Cell death
2008

Exposing plasmids as the Achilles' heel of drug-resistant bacteria

Williams, J. J. & Hergenrother, P., Aug 1 2008, In : Current Opinion in Chemical Biology. 12, 4, p. 389-399 11 p.

Research output: Contribution to journalReview article

Bacteria
Plasmids
Pharmaceutical Preparations
Anti-Bacterial Agents
Antitoxins

Identification of the cellular targets of bioactive small organic molecules using affinity reagents

Leslie, B. J. & Hergenrother, P. J., Jun 30 2008, In : Chemical Society Reviews. 37, 7, p. 1347-1360 14 p.

Research output: Contribution to journalReview article

Molecules
Experiments
Drug Discovery

Targeting RNA with small molecules

Thomas, J. R. & Hergenrother, P. J., Apr 1 2008, In : Chemical reviews. 108, 4, p. 1171-1224 54 p.

Research output: Contribution to journalReview article

RNA
Molecules
Ligands
Macromolecules
Cell culture
2011
Photonic crystals
Biosensors
Modulators
Screening
Throughput

Transcript profiling and RNA interference as tools to identify small molecule mechanisms and therapeutic potential

Palchaudhuri, R. & Hergenrother, P., Jan 21 2011, In : ACS chemical biology. 6, 1, p. 21-32 12 p.

Research output: Contribution to journalReview article

RNA Interference
RNA
Molecules
Pattern matching
Drug Discovery
2012

Artificial activation of toxin-antitoxin systems as an antibacterial strategy

Williams, J. J. & Hergenrother, P., Jun 1 2012, In : Trends in Microbiology. 20, 6, p. 291-298 8 p.

Research output: Contribution to journalReview article

Antitoxins
Bacterial Chromosomes
Bacterial Genomes
Genes
Plasmids
2018

How many human proteoforms are there?

Aebersold, R., Agar, J. N., Amster, I. J., Baker, M. S., Bertozzi, C. R., Boja, E. S., Costello, C. E., Cravatt, B. F., Fenselau, C., Garcia, B. A., Ge, Y., Gunawardena, J., Hendrickson, R. C., Hergenrother, P. J., Huber, C. G., Ivanov, A. R., Jensen, O. N., Jewett, M. C., Kelleher, N. L., Kiessling, L. L. & 33 others, Krogan, N. J., Larsen, M. R., Loo, J. A., Ogorzalek Loo, R. R., Lundberg, E., Maccoss, M. J., Mallick, P., Mootha, V. K., Mrksich, M., Muir, T. W., Patrie, S. M., Pesavento, J. J., Pitteri, S. J., Rodriguez, H., Saghatelian, A., Sandoval, W., Schlüter, H., Sechi, S., Slavoff, S. A., Smith, L. M., Snyder, M. P., Thomas, P. M., Uhlén, M., Van Eyk, J. E., Vidal, M., Walt, D. R., White, F. M., Williams, E. R., Wohlschlager, T., Wysocki, V. H., Yates, N. A., Young, N. L. & Zhang, B., Feb 14 2018, In : Nature chemical biology. 14, 3, p. 206-214 9 p.

Research output: Contribution to journalReview article

Post Translational Protein Processing
Proteins
Proteome
Proteomics
Amino Acid Sequence
2019

The challenge of converting gram-positive-only compounds into broad-spectrum antibiotics

Richter, M. F. & Hergenrother, P. J., Jan 1 2019, In : Annals of the New York Academy of Sciences. 1435, 1, p. 18-38 21 p.

Research output: Contribution to journalReview article

Anti-Bacterial Agents
Escherichia coli
Gram-Negative Bacterial Infections
Guidelines
Pathogens