Research output per year
Research output per year
Personal profile
Research Interests
Research Topics
Computational Biology, Host-Pathogen Interactions
Disease Research Interests
Infectious Diseases
Professional Information
In most pathogens, epidemiological and evolutionary processes occur on similar time scales due to the large population sizes and short generation times. This makes infectious diseases amenable to study and the interplay of their ecology and evolution particularly relevant for both fundamental biology and applied public health. However, temporal and spatial changes in infectious disease dynamics are difficult to anticipate due to the effects of environmental drivers on the transmission of pathogens and the complex diversity that these microorganisms exhibit.
To address these challenges, my research on the ecology and evolution of infectious diseases focuses on the following general questions:
- How do climatic and demographic factors shape the population dynamics of infectious diseases in space and time?
- How does pathogen diversity interact and interfere with public health interventions?
For answering these questions, I use mathematical and computational tools that are applied to different types of time series data.
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Daily longitudinal sampling of SARS-CoV-2 infection reveals substantial heterogeneity in infectiousness
Ke, R., Martinez, P. P., Smith, R. L., Gibson, L. L., Mirza, A., Conte, M., Gallagher, N., Luo, C. H., Jarrett, J., Zhou, R., Conte, A., Liu, T., Farjo, M., Walden, K. K. O., Rendon, G., Fields, C. J., Wang, L., Fredrickson, R., Edmonson, D. C., Baughman, M. E., & 19 others, May 2022, In: Nature Microbiology. 7, 5, p. 640-652 13 p.Research output: Contribution to journal › Article › peer-review
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Longitudinal Analysis of SARS-CoV-2 Vaccine Breakthrough Infections Reveals Limited Infectious Virus Shedding and Restricted Tissue Distribution
Ke, R., Martinez, P. P., Smith, R. L., Gibson, L. L., Achenbach, C. J., McFall, S., Qi, C., Jacob, J., Dembele, E., Bundy, C., Simons, L. M., Ozer, E. A., Hultquist, J. F., Lorenzo-Redondo, R., Opdycke, A. K., Hawkins, C., Murphy, R. L., Mirza, A., Conte, M., Gallagher, N., & 23 others, Jul 2022, In: Open Forum Infectious Diseases. 9, 7, ofac192.Research output: Contribution to journal › Article › peer-review
Open Access -
The neglected role of relative humidity in the interannual variability of urban malaria in Indian cities
Santos-Vega, M., Martinez, P. P., Vaishnav, K. G., Kohli, V., Desai, V., Bouma, M. J. & Pascual, M., Dec 2022, In: Nature communications. 13, 1, 533.Research output: Contribution to journal › Article › peer-review
Open Access -
Daily Sampling of Early SARS-CoV-2 Infection Reveals Substantial Heterogeneity in Infectiousness
Ke, R., Martinez, P. P., Smith, R. L., Gibson, L. L., Mirza, A., Conte, M., Gallagher, N., Luo, C. H., Jarrett, J., Conte, A., Liu, T., Farjo, M., Walden, K. K. O., Rendon, G., Fields, C. J., Wang, L., Fredrickson, R., Edmonson, D. C., Baughman, M. E., Chiu, K. K., & 18 others, Jul 12 2021, (In preparation) Cold Spring Harbor Laboratory Press, 23 p. (medRxiv).Research output: Working paper › Preprint
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Lockdowns result in changes in human mobility which may impact the epidemiologic dynamics of SARS-CoV-2
Kishore, N., Kahn, R., Martinez, P. P., De Salazar, P. M., Mahmud, A. S. & Buckee, C. O., Mar 26 2021, In: Scientific reports. 11, 1, p. 6995 6995.Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
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Study tracks COVID-19 infection dynamics in adults
Christopher Byron Brooke, Pamela Patricia Martinez Vargas & Rebecca Lee Smith
4/28/22
1 Media contribution
Press/Media: Research