Pablo Perez Pinera

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Clustered Regularly Interspaced Short Palindromic Repeats Medicine & Life Sciences
Protein Tyrosine Phosphatases Medicine & Life Sciences
Genes Chemical Compounds
Synthetic Biology Medicine & Life Sciences
Cells Chemical Compounds
Technology Medicine & Life Sciences
Pacinian Corpuscles Medicine & Life Sciences
Zinc Fingers Medicine & Life Sciences

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Research Output 2003 2019

Multiplexed and tunable transcriptional activation by promoter insertion using nuclease-assisted vector integration

Brown, A., Winter, J., Gapinske, M., Tague, N., Woods, W. S. & Perez Pinera, P., Jul 9 2019, In : Nucleic acids research. 47, 12, p. e67

Research output: Contribution to journalArticle

Open Access
Transcriptional Activation
Cell Engineering
Organism Cloning
Transcription Factors

Targeted exon skipping with AAV-mediated split adenine base editors

Winter, J., Luu, A., Gapinske, M., Manandhar, S., Shirguppe, S., Woods, W. S., Song, J. & Perez Pinera, P., Dec 1 2019, In : Cell Discovery. 5, 1, 41.

Research output: Contribution to journalArticle

Open Access
Gene therapy
adenine deaminase
Genetic Therapy

CRISPR-SKIP: Programmable gene splicing with single base editors

Gapinske, M., Luu, A., Winter, J., Woods, W. S., Kostan, K. A., Shiva, N., Song, J. & Perez Pinera, P., Aug 15 2018, In : Genome biology. 19, 1, 107.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Synthetic Biology
Cytidine Deaminase

Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner

Mancini, A., Xavier-Magalhães, A., Woods, W. S., Nguyen, K. T., Amen, A. M., Hayes, J. L., Fellmann, C., Gapinske, M., McKinney, A. M., Hong, C., Jones, L. E., Walsh, K. M., Bell, R. J. A., Doudna, J. A., Costa, B. M., Song, J., Perez Pinera, P. & Costello, J. F., Sep 10 2018, In : Cancer Cell. 34, 3, p. 513-528.e8

Research output: Contribution to journalArticle

Protein Isoforms
Cell Death

Targeted gene knock out using nuclease-assisted vector integration: Hemi- and Homozygous deletion of JAG1

Gapinske, M., Tague, N., Winter, J., Underhill, G. H. & Perez Pinera, P., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 233-248 16 p. (Methods in Molecular Biology; vol. 1772).

Research output: Chapter in Book/Report/Conference proceedingChapter

Gene Knockout Techniques