Research output per year
Research output per year
Personal profile
Research Interests
Research Topics
Immunology, Virology, Molecular Evolution, Protein Structure, Bioinformatics
Disease Research Interests
Infectious Diseases
Education
Postdoc, The Scripps Research Institute, 2020
Ph.D., University of California, Los Angeles, 2015
B.S., University of Virginia, 2010
Professional Information
The Wu lab focuses on three research questions:
- What are the constraints of virus evolution?
- Can we predict antibody specificity?
- Can we improve the quality and speed of vaccine design?
The Wu lab addresses these questions mainly in the context of influenza virus and SARS-CoV-2, using molecular virology, protein biochemistry, next-generation sequencing, high-throughput assays, x-ray crystallography, cryo-EM, and machine learning.
Honors & Awards
Viruses Early Career Investigator Award (2022)
UIUC MCB Outstanding Junior Faculty Award (2022)
ASV Ann Palmenberg Junior Investigator Award (2022)
Searle Scholar Award (2022)
Michelson Prize (2021)
ESWI Young Scientist Innovative Award (2021)
NIH Director's New Innovator Award (2021)
NIH Pathway to Independence Award (2019)
Croucher Postdoctoral Fellowship (2015-2017)
Office Phone
(217) 300-9239
Fingerprint
Fingerprint is based on mining the text of the expert's scholarly documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Age-related seroprevalence trajectories of seasonal coronaviruses in children including neonates in Guangzhou, China
Luo, Y., Lv, H., Zhao, S., Sun, Y., Liu, C., Chen, C., Liang, W., Kwok, K. O., Teo, Q. W., So, R. TY., Lin, Y., Deng, Y., Li, B., Dai, Z., Zhu, J., Zhang, D., Fernando, J., Wu, N. C., Tun, H. M., Bruzzone, R., & 2 others, Feb 2023, In: International Journal of Infectious Diseases. 127, p. 26-32 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A TLR7-nanoparticle adjuvant promotes a broad immune response against heterologous strains of influenza and SARS-CoV-2
Yin, Q., Luo, W., Mallajosyula, V., Bo, Y., Guo, J., Xie, J., Sun, M., Verma, R., Li, C., Constantz, C. M., Wagar, L. E., Li, J., Sola, E., Gupta, N., Wang, C., Kask, O., Chen, X., Yuan, X., Wu, N. C., Rao, J., & 4 others, Mar 2023, In: Nature Materials. 22, 3, p. 380-390 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike
Tan, T. J. C., Mou, Z., Lei, R., Ouyang, W. O., Yuan, M., Song, G., Andrabi, R., Wilson, I. A., Kieffer, C., Dai, X., Matreyek, K. A. & Wu, N. C., Dec 2023, In: Nature communications. 14, 1, 2003.Research output: Contribution to journal › Article › peer-review
Open Access -
Mutational fitness landscape of human influenza H3N2 neuraminidase
Lei, R., Hernandez Garcia, A., Tan, T. J. C., Teo, Q. W., Wang, Y., Zhang, X., Luo, S., Nair, S. K., Peng, J. & Wu, N. C., Jan 31 2023, In: Cell Reports. 42, 1, 111951.Research output: Contribution to journal › Article › peer-review
Open Access -
A large-scale systematic survey reveals recurring molecular features of public antibody responses to SARS-CoV-2
Wang, Y., Yuan, M., Lv, H., Peng, J., Wilson, I. A. & Wu, N. C., Jun 14 2022, In: Immunity. 55, 6, p. 1105-1117.e4Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
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Machine-learning model can distinguish antibody targets
4/21/22
1 item of Media coverage
Press/Media: Research
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Antibodies from original strain COVID-19 infection don't bind to variants, study finds
Beth Marie Stadtmueller, Christopher Byron Brooke & Nicholas Ching Hai Wu
9/17/21
1 Media contribution
Press/Media: Research
Honors & Recognition
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ESWI Young Scientist Vaccine Innovation Award
Wu, Nicholas Ching Hai (Recipient), 2021
Prize: Prize/Award
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