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Fingerprint Fingerprint is based on mining the text of the expert's scholarly documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 2 Similar Profiles
Tretinoin Medicine & Life Sciences
Retinoids Medicine & Life Sciences
Embryonal Carcinoma Stem Cells Medicine & Life Sciences
Embryonal Carcinoma Medicine & Life Sciences
Reduced Folate Carrier Protein Medicine & Life Sciences
Leukemia L1210 Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Cells Chemical Compounds

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Research Output 1989 2019

Epigenetic Remodeling through Downregulation of Polycomb Repressive Complex 2 Mediates Chemotherapy Resistance in Testicular Germ Cell Tumors

Singh, R., Fazal, Z., Corbet, A. K., Bikorimana, E., Rodriguez, J. C., Khan, E. M., Shahid, K., Spinella, S. J. & Spinella, M. J., Jun 8 2019, In : Cancers. 11, 6, 796.

Research output: Contribution to journalArticle

Open Access
Polycomb Repressive Complex 2
Epigenomics
Cisplatin
Down-Regulation
Methylation

The potential of retinoids for combination therapy of lung cancer: Updates and future directions

Tripathi, S. K., Pandey, K., Panda, M., Spinella, M. J., Rengasamy, K. RR. & Biswal, B. K., Sep 2019, In : Pharmacological Research. 147, 104331.

Research output: Contribution to journalReview article

Retinoids
Lung Neoplasms
Therapeutics
Tretinoin
Antineoplastic Agents

Incorporating DNA Methyltransferase Inhibitors (DNMTis) in the Treatment of Genitourinary Malignancies: A Systematic Review

Chovanec, M., Taza, F., Kalra, M., Hahn, N., Nephew, K. P., Spinella, M. J. & Albany, C., Feb 1 2018, In : Targeted Oncology. 13, 1, p. 49-60 12 p.

Research output: Contribution to journalReview article

Methyltransferases
DNA
Neoplasms
Tumor Suppressor Genes
Therapeutics

G0S2 represses PI3K/mTOR signaling and increases sensitivity to PI3K/mTOR pathway inhibitors in breast cancer

Yim, C. Y., Bikorimana, E., Khan, E., Warzecha, J. M., Shin, L., Rodriguez, J., Dmitrovsky, E., Freemantle, S. J. & Spinella, M. J., Nov 2 2017, In : Cell Cycle. 16, 21, p. 2146-2155 10 p.

Research output: Contribution to journalArticle

Switch Genes
Phosphatidylinositol 3-Kinases
Breast Neoplasms
Estrogen Receptor Modulators
Gene Expression

Refractory testicular germ cell tumors are highly sensitive to the second generation DNA methylation inhibitor guadecitabine

Albany, C., Hever-Jardine, M. P., von Herrmann, K. M., Yim, C. Y., Tam, J., Warzecha, J. M., Shin, L., Bock, S. E., Curran, B. S., Chaudhry, A. S., Kim, F., Sandusky, G. E., Taverna, P., Freemantle, S. J., Christensen, B. C., Einhorn, L. H. & Spinella, M. J., Jan 1 2017, In : Oncotarget. 8, 2, p. 2949-2959 11 p.

Research output: Contribution to journalArticle

DNA Methylation
Embryonal Carcinoma Stem Cells
Cisplatin
Embryonal Carcinoma
Deoxycytidine