Personal profile
Professional Information
The Kraft group combines engineering principles and cutting-edge imaging technologies to overcome barriers to progress in biomedical research. We focus on identifying, and exploiting the relationship between cell composition and biological function. A key aspect of our research is the combination of computational statistics with chemical imaging techniques for quantitative single cell analysis with location specificity. We are using our new tools to solve problems in a broad range of biomedical research areas. This includes applied research in directing stem cell differentiation for tissue engineering and the design of efficient drug delivery vehicles. We also perform basic research on influenza virus replication.
Office Address
Department of Chemical and Biomolecular Engineering
University of Illinois
600 S Mathews Ave
208 RAL, MC-712
Urbana, IL 61801
Office Phone
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Collaborations and top research areas from the last five years
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Depth Correction of TOF-SIMS Depth Profiling Images Using the Total Ion Count Images
Brunet, M. A., Gorman, B. L. & Kraft, M. L., Sep 2025, In: Biomolecules. 15, 9, 1237.Research output: Contribution to journal › Article › peer-review
Open Access -
Noninvasive and in situ identification of the phenotypes and differentiation stages of individual living cells entrapped within hydrogels
Pastrana-Otero, I., Godbole, A. R. & Kraft, M. L., May 21 2025, In: Analyst. 150, 10, p. 2047-2057 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Toward Understanding the Subcellular Distributions of Cholesterol and Sphingolipids Using High-Resolution NanoSIMS Imaging
Brunet, M. A. & Kraft, M. L., Apr 4 2023, In: Accounts of chemical research. 56, 7, p. 752-762 11 p.Research output: Contribution to journal › Article › peer-review
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Depth Correction of 3D NanoSIMS Images Shows Intracellular Lipid and Cholesterol Distributions while Capturing the Effects of Differential Sputter Rate
Brunet, M. A., Gorman, B. L. & Kraft, M. L., Oct 25 2022, In: ACS Nano. 16, 10, p. 16221-16233 13 p.Research output: Contribution to journal › Article › peer-review
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Identification of the Differentiation Stages of Living Cells from the Six Most Immature Murine Hematopoietic Cell Populations by Multivariate Analysis of Single-Cell Raman Spectra
Pastrana-Otero, I., Majumdar, S., Gilchrist, A. E., Harley, B. A. C. & Kraft, M. L., Sep 6 2022, In: Analytical Chemistry. 94, 35, p. 11999-12007 9 p.Research output: Contribution to journal › Article › peer-review
Datasets
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Raman spectra of individual, living hematopoietic stem and progenitor cells
Pastrana-Otero, I. (Creator), Majumdar, S. (Creator) & Kraft, M. L. (Creator), University of Illinois Urbana-Champaign, Aug 22 2022
DOI: 10.13012/B2IDB-9950442_V1
Dataset
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Data for Noninvasive and In Situ Identification of the Phenotypes and Differentiation Stages of Individual Living Cells Entrapped Within Hydrogels
Pastrana-Otero, I. (Creator), Godbole, A. R. (Creator) & Kraft, M. L. (Creator), University of Illinois Urbana-Champaign, Apr 2 2025
DOI: 10.13012/B2IDB-5669414_V1
Dataset
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TOF-SIMS depth profiling data of a transfected HEK cell
Kraft, M. L. (Creator), Fisher, G. L. (Creator), Chini, C. E. (Creator), Gorman, B. L. (Creator) & Brunet, M. A. (Creator), University of Illinois Urbana-Champaign, Aug 26 2025
DOI: 10.13012/B2IDB-5513643_V1
Dataset
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NanoSIMS depth profiling data of an MDCK cell
Kraft, M. L. (Creator), Yeager, A. N. (Creator) & Weber, P. K. (Creator), University of Illinois Urbana-Champaign, Jun 24 2021
DOI: 10.13012/B2IDB-3927212_V1
Dataset
Honors & Recognition
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Walter A. Shaw Young Investigator Award in Lipid Research
Kraft, M. (Recipient), 2014
Prize: Prize/Award