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Molecules Chemical Compounds
Boronic Acids Chemical Compounds
Amphotericin B Medicine & Life Sciences
Biological Products Chemical Compounds
Polyenes Chemical Compounds
Ion Channels Medicine & Life Sciences
Acids Engineering & Materials Science
Sterols Medicine & Life Sciences

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Research Output 1998 2019

Axial shielding of Pd(II) complexes enables perfect stereoretention in Suzuki-Miyaura cross-coupling of Csp 3 boronic acids

Lehmann, J. W., Crouch, I. T., Blair, D. J., Trobe, M., Wang, P., Li, J. & Burke, M., Dec 1 2019, In : Nature communications. 10, 1, 1263.

Research output: Contribution to journalArticle

Open Access
Boronic Acids
cross coupling
Shielding
shielding
acids

Modular Syntheses of Phenanthroindolizidine Natural Products

Jo, Y. I., Burke, M. & Cheon, C. H., Jun 7 2019, In : Organic Letters. 21, 11, p. 4201-4204 4 p.

Research output: Contribution to journalArticle

Boronic Acids
Vanadium
Biological Products
Bromides
Alkaloids

Small-molecule ion channels increase host defences in cystic fibrosis airway epithelia

Muraglia, K. A., Chorghade, R. S., Kim, B. R., Tang, X. X., Shah, V. S., Grillo, A. S., Daniels, P. N., Cioffi, A. G., Karp, P. H., Zhu, L., Welsh, M. J. & Burke, M. D., Mar 21 2019, In : Nature. 567, 7748, p. 405-408 4 p.

Research output: Contribution to journalLetter

Cystic Fibrosis Transmembrane Conductance Regulator
Ion Channels
Cystic Fibrosis
Amphotericin B
Epithelium

FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity

Yien, Y. Y., Shi, J., Chen, C., Cheung, J. T. M., Grillo, A. S., Shrestha, R., Li, L., Zhang, X., Kafina, M. D., Kingsley, P. D., King, M. J., Ablain, J., Li, H., Zon, L. I., Palis, J., Burke, M., Bauer, D. E., Orkin, S. H., Koehler, C. M., Phillips, J. D. & 4 others, Kaplan, J., Ward, D. M., Lodish, H. F. & Paw, B. H., Jan 1 2018, In : Journal of Biological Chemistry. 293, 51, p. 19797-19811 15 p.

Research output: Contribution to journalArticle

Ferrochelatase
Erythropoietin
Heme
Iron
Erythropoiesis

Peridinin Is an Exceptionally Potent and Membrane-Embedded Inhibitor of Bilayer Lipid Peroxidation

Haley, H. M. S., Hill, A. G., Greenwood, A. I., Woerly, E. M., Rienstra, C. & Burke, M., Nov 14 2018, In : Journal of the American Chemical Society. 140, 45, p. 15227-15240 14 p.

Research output: Contribution to journalArticle

Lipid bilayers
Endothelial cells
inhibitor
lipid
Lipid Peroxidation