M Taher A Saif

1988 …2019
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Research Output 1988 2019

2019

A novel technique for in situ uniaxial tests of self-assembled soft biomaterials

Elhebeary, M., Emon, M. A. B., Aydin, O. & Saif, M. T. A., Jan 1 2019, In : Lab on a Chip. 19, 7, p. 1153-1161 9 p.

Research output: Contribution to journalArticle

Biocompatible Materials
Biomaterials
Tissue
Collagen
Electric Stimulation

Cancer Cells Invade Confined Microchannels via a Self-Directed Mesenchymal-to-Amoeboid Transition

Holle, A. W., Govindan Kutty Devi, N., Clar, K., Fan, A., Saif, M. T. A., Kemkemer, R. & Spatz, J. P., Apr 10 2019, In : Nano Letters. 19, 4, p. 2280-2290 11 p.

Research output: Contribution to journalArticle

microchannels
Microchannels
cancer
Cells
matrices

Phase Dependent Mechanosensitivity in Cardiomyocytes

Williams, B. J. & Saif, M. T. A., Mar 15 2019, In : Experimental Mechanics. 59, 3, p. 387-393 7 p.

Research output: Contribution to journalArticle

Substrates
Rats
Tissue
Ions

Recent Advances in Micro, Nano, and Cell Mechanics

Zhu, Y., Saif, M. T. A. & DelRio, F. W., Jan 1 2019, In : Experimental Mechanics.

Research output: Contribution to journalEditorial

Open Access
Mechanics
2018

A novel MEMS stage for in-situ thermomechanical testing of single crystal silicon microbeams under bending

Elhebeary, M. & Saif, M. T. A., Sep 1 2018, In : Extreme Mechanics Letters. 23, p. 1-8 8 p.

Research output: Contribution to journalArticle

Silicon
MEMS
Single crystals
Testing
Bending tests

A simple microfluidic platform for the partial treatment of insuspendable tissue samples with orientation control

Fan, A., Tofangchi, A., De Venecia, M. & Saif, M. T. A., Mar 7 2018, In : Lab on a chip. 18, 5, p. 735-742 8 p.

Research output: Contribution to journalArticle

Microfluidics
Axons
Lab-On-A-Chip Devices
Tissue
Microchannels

Biophysics of Tumor Microenvironment and Cancer Metastasis - A Mini Review

Emon, B., Bauer, J., Jain, Y., Jung, B. & Saif, M. T. A., Jan 1 2018, In : Computational and Structural Biotechnology Journal. 16, p. 279-287 9 p.

Research output: Contribution to journalReview article

Biophysics
Tumor Microenvironment
Tumors
Cells
Neoplasm Metastasis

Cell-Extracellular Matrix Mechanobiology: Forceful Tools and Emerging Needs for Basic and Translational Research

Holle, A. W., Young, J. L., Van Vliet, K. J., Kamm, R. D., Discher, D., Janmey, P., Spatz, J. P. & Saif, M. T. A., Jan 10 2018, In : Unknown Journal. 18, 1, p. 1-8 8 p.

Research output: Contribution to journalReview article

emerging
Mechanics
cues
Signal transduction
Neurology

Correction to: Simulation and Fabrication of Stronger, Larger, and Faster Walking Biohybrid Machines (Advanced Functional Materials, (2018), 28, 23, (1801145), 10.1002/adfm.201801145)

Pagan-Diaz, G. J., Zhang, X., Grant, L., Kim, Y., Aydin, O., Cvetkovic, C., Ko, E., Solomon, E., Hollis, J., Kong, H. J., Saif, M. T. A., Gazzola, M. & Bashir, R., Aug 15 2018, In : Advanced Functional Materials. 28, 33, 1804580.

Research output: Contribution to journalComment/debate

walking machines
Functional materials
lists
Fabrication
fabrication

Cytotoxicity and in Vitro Degradation Kinetics of Foundry-Compatible Semiconductor Nanomembranes and Electronic Microcomponents

Chang, J. K., Emon, M. A. B., Li, C. S., Yang, Q., Chang, H. P., Yang, Z., Wu, C. I., Saif, M. T. A. & Rogers, J. A., Jan 1 2018, (Accepted/In press) In : ACS Nano.

Research output: Contribution to journalArticle

foundries
Microsystems
Foundries
Cytotoxicity
Semiconductor materials

Simulation and Fabrication of Stronger, Larger, and Faster Walking Biohybrid Machines

Pagan-Diaz, G. J., Zhang, X., Grant, L., Kim, Y., Aydin, O., Cvetkovic, C., Ko, E., Solomon, E., Hollis, J., Kong, H. J., Saif, M. T. A., Gazzola, M. & Bashir, R., Jun 6 2018, In : Advanced Functional Materials. 28, 23, 1801145.

Research output: Contribution to journalArticle

walking machines
Scaffolds
Robotics
Actuators
Tissue

Small-scale displacement fluctuations of vesicles in fibroblasts

Posey, D., Blaisdell-Pijuan, P., Knoll, S. K., Saif, M. T. A. & Ahmed, W. W., Dec 1 2018, In : Scientific Reports. 8, 1, 13294.

Research output: Contribution to journalArticle

Myosin Type II
Fibroblasts
Organelles
Cytoplasm
Cytoskeletal Proteins
2017

Coupled circumferential and axial tension driven by actin and myosin influences in vivo axon diameter

Fan, A., Tofangchi, A., Kandel, M., Popescu, G. & Saif, M. T. A., Dec 1 2017, In : Scientific Reports. 7, 1, 14188.

Research output: Contribution to journalArticle

Myosins
Microtubules
Axons
Actins
Interference Microscopy

Design, Simulation, and Testing of a Novel Bending Stage for Mechanical Characterization of Materials

Elhebeary, M. & Saif, M. T. A., Jan 1 2017, In : Experimental Mechanics. 57, 1, p. 89-96 8 p.

Research output: Contribution to journalArticle

Elastic moduli
Bending tests
Testing
Numerical models
Analytical models

Lessons learned from nanoscale specimens tested by MEMS-based apparatus

Elhebeary, M. & Saif, M. T. A., May 19 2017, In : Journal of Physics D: Applied Physics. 50, 24, 243001.

Research output: Contribution to journalReview article

lessons learned
microelectromechanical systems
MEMS
materials tests
prognosis

Thermo-mechanical characterization of materials at micro/nanoscal E under bending

Elhebeary, M. & Saif, M. T. A., Feb 23 2017, 2017 IEEE 30th International Conference on Micro Electro Mechanical Systems, MEMS 2017. Institute of Electrical and Electronics Engineers Inc., p. 736-739 4 p. 7863513. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Silicon
Single crystals
single crystals
silicon
Scanning electron microscopy
2016

Corrigendum: Contractile dynamics change before morphological cues during fluorescence illumination

Knoll, S. G., Ahmed, W. W. & Saif, M. T. A., Feb 18 2016, In : Scientific Reports. 6, 21218.

Research output: Contribution to journalComment/debate

Emergent dynamics of cardiomyocyte clusters on deformable polymeric substrates

Anand, S. V. & Saif, M. T. A., Sep 1 2016, In : Extreme Mechanics Letters. 8, p. 1-5 5 p.

Research output: Contribution to journalArticle

Substrates
Polymer films
Feedback
Thin films
Direction compound

Induced coupling between contractile cells

Williams, B. J. & Saif, M. T. A., Jan 1 2016, Mechanics of Biological Systems and Materials - Proceedings of the 2015 Annual Conference on Experimental and Applied Mechanics. Korach, C. S., Tekalur, S. A. & Zavattieri, P. (eds.). Springer New York LLC, p. 91-97 7 p. (Conference Proceedings of the Society for Experimental Mechanics Series; vol. 6).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Substrates
Tissue
Tensile strain
Communication
Cell culture

Light induced, localized, and abrupt force relaxations in fibroblast cells on soft substrates

Knoll, S. G. & Saif, M. T. A., Sep 1 2016, In : Extreme Mechanics Letters. 8, p. 257-265 9 p.

Research output: Contribution to journalArticle

Fibroblasts
Cells
Substrates
Myosins
Polyacrylates

Matrix directed adipogenesis and neurogenesis of mesenchymal stem cells derived from adipose tissue and bone marrow

Lee, J., Abdeen, A. A., Tang, X., Saif, T. A. & Kilian, K. A., Sep 15 2016, In : Acta Biomaterialia. 42, p. 46-55 10 p.

Research output: Contribution to journalArticle

Adipogenesis
Neurogenesis
Stem cells
Mesenchymal Stromal Cells
Adipose Tissue

Mechanism of Axonal Contractility in Embryonic Drosophila Motor Neurons In Vivo

Tofangchi, A., Fan, A. & Saif, M. T. A., Oct 4 2016, In : Biophysical journal. 111, 7, p. 1519-1527 9 p.

Research output: Contribution to journalArticle

Motor Neurons
Drosophila
Axons
Microtubules
Actomyosin
2015
mechanical properties
Analytical models
Mechanical properties
deflection
Bending tests

Cardiac muscle organization revealed in 3-D by imaging whole-mount mouse hearts using twophoton fluorescence and confocal microscopy

Sivaguru, M., Fried, G. A., Sivaguru, B. S., Sivaguru, V. A., Lu, X., Choi, K. H., Saif, M. T. A., Lin, B. & Sadayappan, S., Nov 1 2015, In : BioTechniques. 59, 5, p. 295-308 14 p.

Research output: Contribution to journalArticle

Three-Dimensional Imaging
Confocal microscopy
Fluorescence microscopy
Fluorescence Microscopy
Confocal Microscopy

Cell culture on microfabricated one-dimensional polymeric structures for bio-actuator and bio-bot applications

Anand, S. V., Yakut Ali, M. & Saif, M. T. A., Apr 21 2015, In : Lab on a Chip. 15, 8, p. 1879-1888 10 p.

Research output: Contribution to journalArticle

Cell culture
Actuators
Cell Culture Techniques
Skeletal Muscle Fibers
Substrates

Contractile dynamics change before morphological cues during florescence illumination

Knoll, S. G., Ahmed, W. W. & Saif, M. T. A., Dec 22 2015, In : Scientific Reports. 5, 18513.

Research output: Contribution to journalArticle

Lighting
Cues
Fiducial Markers
Light
Hydrogels

Geometric guidance of integrin mediated traction stress during stem cell differentiation

Lee, J., Abdeen, A. A., Tang, X., Saif, T. A. & Kilian, K. A., Nov 1 2015, In : Biomaterials. 69, p. 174-183 10 p.

Research output: Contribution to journalArticle

Focal Adhesions
Traction
Stem cells
Integrins
Cell Differentiation

Isolation of primary human colon tumor cells from surgical tissues and culturing them directly on soft elastic substrates for traction cytometry

Ali, M. Y., Anand, S. V., Tangella, K., Ramkumar, D. & Saif, M. T. A., Jun 4 2015, In : Journal of Visualized Experiments. 2015, 100, e52532.

Research output: Contribution to journalArticle

Traction (friction)
Traction
Tumors
Colon
Cells

Modification of a colliculo-thalamocortical mouse brain slice, incorporating 3-D printing of chamber components and multi-scale optical imaging

Slater, B. J., Fan, A. Y., Stebbings, K. A., Saif, M. T. A. & Llano, D. A., Sep 18 2015, In : Journal of Visualized Experiments. 2015, 103, e53067.

Research output: Contribution to journalArticle

Optical Imaging
Prosencephalon
Printing
Brain
Geniculate Bodies

Stretch induced hyperexcitability of mice callosal pathway

Fan, A., Stebbings, K. A., Llano, D. A. & Saif, T., Aug 5 2015, In : Frontiers in Cellular Neuroscience. 9, AUGUST, 292.

Research output: Contribution to journalArticle

Corpus Callosum
Flavoproteins
Brain
Biochemical Phenomena
Neuronal Plasticity
2014

Active transport of vesicles in neurons is modulated by mechanical tension

Ahmed, W. W. & Saif, M. T. A., Mar 27 2014, In : Scientific Reports. 4, 4481.

Research output: Contribution to journalArticle

Transport Vesicles
Active Biological Transport
Neurons
Neurites
Aplysia

A mechanically-induced colon cancer cell population shows increased metastatic potential

Tang, X., Kuhlenschmidt, T. B., Li, Q., Ali, S., Lezmi, S., Chen, H., Pires Alves, M., Laegreid, W. W., Saif, M. T. A. & Kuhlenschmidt, M. S., May 29 2014, In : Molecular Cancer. 13, 1, 131.

Research output: Contribution to journalArticle

Colonic Neoplasms
Population
Neoplasm Metastasis
Anoikis
Tumor Microenvironment

A microfabricated, biohybrid, soft robotics flagellum

Williams, B. J., Anand, S. V., Rajagopalan, J. & Saif, M. T. A., 2014, MEMS 2014 - 27th IEEE International Conference on Micro Electro Mechanical Systems. Institute of Electrical and Electronics Engineers Inc., p. 192-195 4 p. 6765607

Research output: Chapter in Book/Report/Conference proceedingConference contribution

propulsion
robotics
Propulsion
filaments
Robotics

A Novel Cell Traction Force Microscopy to Study Multi-Cellular System

Tang, X., Tofangchi, A., Anand, S. V. & Saif, M. T. A., Jan 1 2014, In : PLoS Computational Biology. 10, 6, e1003631.

Research output: Contribution to journalArticle

traction (mechanics)
Cellular Systems
Atomic Force Microscopy
Traction
Microscopy

A novel method for localizing reporter fluorescent beads near the cell culture surface for traction force microscopy

Knoll, S. G., Yakut Ali, M. & Saif, M. T. A., Sep 16 2014, In : Journal of Visualized Experiments. 91, e51873.

Research output: Contribution to journalArticle

Atomic Force Microscopy
Traction
Cell culture
Microscopic examination
Gels

A self-propelled biohybrid swimmer at low Reynolds number

Williams, B. J., Anand, S. V., Rajagopalan, J. & Saif, M. T. A., Jan 17 2014, In : Nature communications. 5, 3081.

Research output: Contribution to journalArticle

Flagella
low Reynolds number
Cardiac Myocytes
filaments
Reynolds number

Reprogramming cellular phenotype by soft collagen gels

Ali, M. Y., Chuang, C. Y. & Saif, M. T. A., Nov 28 2014, In : Soft Matter. 10, 44, p. 8829-8837 9 p.

Research output: Contribution to journalArticle

phenotype
collagens
Collagen
Gels
gels
Metastasis
Adhesion
Phenotype
Colonic Neoplasms
Stiffness

Three-dimensionally printed biological machines powered by skeletal muscle

Cvetkovic, C., Raman, R., Chan, V., Williams, B. J., Tolish, M., Bajaj, P., Sakar, M. S., Asada, H. H., Saif, M. T. A. & Bashir, R., Jul 15 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 28, p. 10125-10130 6 p.

Research output: Contribution to journalArticle

Skeletal Muscle
Hydrogel
Locomotion
Electric Power Supplies
Biomimetics
2013

Adhesivity of colon cancer cells during in vitro metastasis

Tang, X. & Saif, M. T. A., Sep 1 2013, In : International Journal of Applied Mechanics. 5, 3, 1350025.

Research output: Contribution to journalArticle

Adhesion
Cells
Cell adhesion
Substrates
Fracture mechanics

Artificial swimmer powered by cardiomyocytes

Williams, B., Anand, S., Rajagopalan, J. & Saif, M. T. A., Dec 1 2013, ASME 2013 Summer Bioengineering Conference, SBC 2013. (ASME 2013 Summer Bioengineering Conference, SBC 2013; vol. 1 A).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Cardiac Myocytes

Cardiac myocytes' dynamic contractile behavior differs depending on heart segment

De Souza, E. J., Ahmed, W., Chan, V., Bashir, R. & Saif, T., Feb 1 2013, In : Biotechnology and bioengineering. 110, 2, p. 628-636 9 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Muscle Cells
Video Microscopy
Microscopic examination

Fabrication of freestanding 1-D PDMS microstructures using capillary micromolding

Rajagopalan, J. & Saif, M. T. A., Jun 25 2013, In : Journal of Microelectromechanical Systems. 22, 5, p. 992-994 3 p., 6541951.

Research output: Contribution to journalArticle

Polydimethylsiloxane
Fabrication
Microstructure
Cytology
Capillary flow

In situ study of size and temperature dependent brittle-to-ductile transition in single crystal silicon

Kang, W. & Saif, M. T. A., Feb 11 2013, In : Advanced Functional Materials. 23, 6, p. 713-719 7 p.

Research output: Contribution to journalArticle

Silicon
Single crystals
Superconducting transition temperature
single crystals
silicon

In vitro cancer metastasis induced by mechanical force

Tang, X. & Saif, M. T. A., Dec 16 2013, ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology, NEMB 2013. NEMB2013-93130. (ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology, NEMB 2013).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Neoplasm Metastasis
Neoplasms
In Vitro Techniques
Medicine
Phenotype

Measuring nonequilibrium vesicle dynamics in neurons under tension

Ahmed, W. W., Williams, B. J., Silver, A. M. & Saif, M. T. A., Feb 21 2013, In : Lab on a Chip. 13, 4, p. 570-578 9 p.

Research output: Contribution to journalArticle

Transport Vesicles
Neurons
Active Biological Transport
Scaling laws
Aplysia

Tailoring hydrogel adhesion to polydimethylsiloxane substrates using polysaccharide glue

Cha, C., Antoniadou, E., Lee, M., Jeong, J. H., Ahmed, W. W., Saif, T. A., Boppart, S. A. & Kong, H., Jul 1 2013, In : Angewandte Chemie - International Edition. 52, 27, p. 6949-6952 4 p.

Research output: Contribution to journalArticle

Glues
Hydrogel
Polydimethylsiloxane
Polysaccharides
Hydrogels
2012

A novel technique for micro-patterning proteins and cells on polyacrylamide gels

Tang, X., Yakut Ali, M. & Saif, M. T. A., Jul 21 2012, In : Soft Matter. 8, 27, p. 7197-7206 10 p.

Research output: Contribution to journalArticle

Gels
gels
proteins
Glass
cells

Attenuation of Cell Mechanosensitivity in Colon Cancer Cells during In Vitro Metastasis

Tang, X., Wen, Q., Kuhlenschmidt, T. B., Kuhlenschmidt, M. S., Janmey, P. A. & Saif, M. T. A., Nov 30 2012, In : PloS one. 7, 11, e50443.

Research output: Contribution to journalArticle

colorectal neoplasms
metastasis
Colonic Neoplasms
Cells
Neoplasm Metastasis

Development of miniaturized walking biological machines

Chan, V., Park, K., Collens, M. B., Kong, H., Saif, T. A. & Bashir, R., Dec 14 2012, In : Scientific Reports. 2, 857.

Research output: Contribution to journalArticle

Locomotion
Cardiac Myocytes
Walking
Leg
Hydrogels