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Research Output 1996 2019

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Article
2019

Genistein inhibits proliferation and induces senescence in neonatal mouse pituitary gland explant cultures

Weis, K. E. & Raetzman, L. T., Nov 1 2019, In : Toxicology. 427, 152306.

Research output: Contribution to journalArticle

Genistein
Pituitary Gland
Messenger RNA
Cells
Estrogen Receptors
2018

Age- and sex-dependent effects of methamphetamine on cognitive flexibility and 5-HT 2C receptor localization in the orbitofrontal cortex of Sprague-Dawley rats

Hankosky, E. R., Westbrook, S. R., Haake, R. M., Willing, J., Raetzman, L. T., Juraska, J. M. & Gulley, J. M., Sep 3 2018, In : Behavioural Brain Research. 349, p. 16-24 9 p.

Research output: Contribution to journalArticle

Receptor, Serotonin, 5-HT2C
Methamphetamine
Prefrontal Cortex
Parvalbumins
Sprague Dawley Rats

Anterior pituitary transcriptome suggests differences in ACTH release in tame and aggressive foxes

Hekman, J. P., Johnson, J. L., Edwards, W., Vladimirova, A. V., Gulevich, R. G., Ford, A. L., Kharlamova, A. V., Herbeck, Y., Acland, G. M., Raetzman, L. T., Trut, L. N. & Kukekova, A. V., Mar 1 2018, In : G3: Genes, Genomes, Genetics. 8, 3, p. 859-873 15 p.

Research output: Contribution to journalArticle

Transcriptome
Adrenocorticotropic Hormone
Pseudopodia
Exocytosis
Aggression

Cellular fate decisions in the developing female anteroventral periventricular nucleus are regulated by canonical Notch signaling

Biehl, M. J., Kaylan, K. B., Thompson, R. J., Gonzalez, R. V., Weis, K. E., Underhill, G. H. & Raetzman, L. T., Oct 1 2018, In : Developmental Biology. 442, 1, p. 87-100 14 p.

Research output: Contribution to journalArticle

Anterior Hypothalamus
Kisspeptins
Neurons
Neuroglia
Cell Proliferation

Effects of exposure to the endocrine-Disrupting chemical bisphenol a during critical windows of murine pituitary development

Eckstrum, K. S., Edwards, W., Banerjee, A., Wang, W., Flaws, J. A., Katzenellenbogen, J. A., Kim, S. H. & Raetzman, L. T., Jan 1 2018, In : Endocrinology. 159, 1, p. 119-131 13 p.

Research output: Contribution to journalArticle

Endocrine Disruptors
Estrogen Receptors
Messenger RNA
Embryonic Development
Gene Expression

Spatial patterning of liver progenitor cell differentiation mediated by cellular contractility and Notch signaling

Kaylan, K. B., Berg, I. C., Biehl, M. J., Brougham-Cook, A., Jain, I., Jamil, S. M., Sargeant, L. H., Cornell, N. J., Raetzman, L. T. & Underhill, G. H., Dec 1 2018, In : eLife. 7, e38536.

Research output: Contribution to journalArticle

Liver
Cell Differentiation
Stem Cells
Cues
Hepatocytes
2016

Icam5 expression exhibits sex differences in the neonatal pituitary and is regulated by estradiol and bisphenol A

Eckstrum, K. S., Weis, K. E., Baur, N. G., Yoshihara, Y. & Raetzman, L. T., Apr 2016, In : Endocrinology. 157, 4, p. 1408-1420 13 p.

Research output: Contribution to journalArticle

Sex Characteristics
Estradiol
Endocrine Disruptors
Pituitary Gland
Genes

Identification of a novel progenitor cell marker, grainyhead-like 2 in the developing pituitary

Edwards, W., Nantie, L. B. & Raetzman, L. T., Nov 1 2016, In : Developmental Dynamics. 245, 11, p. 1097-1106 10 p.

Research output: Contribution to journalArticle

Stem Cells
Maintenance
Endocrine Cells
Pituitary Gland
Cell Differentiation
Estrogen Receptors
Pituitary Gland
Cell proliferation
Tumors
Cyclin-Dependent Kinase Inhibitor Proteins
2015

Persistent expression of activated notch in the developing hypothalamus affects survival of pituitary progenitors and alters pituitary structure

Aujla, P. K., Bogdanovic, V., Naratadam, G. T. & Raetzman, L. T., Aug 1 2015, In : Developmental Dynamics. 244, 8, p. 921-934 14 p.

Research output: Contribution to journalArticle

Hypothalamus
Notch Receptors
Posterior Hypothalamus
Organogenesis
Pituitary Gland

Rbpj-κ mediated Notch signaling plays a critical role in development of hypothalamic Kisspeptin neurons

Biehl, M. J. & Raetzman, L. T., Oct 15 2015, In : Developmental Biology. 406, 2, p. 235-246 12 p.

Research output: Contribution to journalArticle

Kisspeptins
Neurons
Arcuate Nucleus of Hypothalamus
Neuropeptide Y
2014

Notch signaling in postnatal pituitary expansion: Proliferation, progenitors, and cell specification

Nantie, L. B., Himes, A. D., Getz, D. R. & Raetzman, L. T., May 2014, In : Molecular Endocrinology. 28, 5, p. 731-744 14 p.

Research output: Contribution to journalArticle

Stem Cells
Pituitary Hormones
Maintenance
Hormones
Mutation
2013

Notch/Rbpjκ signaling regulates progenitor maintenance and differentiation of hypothalamic arcuate neurons

Aujla, P. K., Naratadam, G. T., Xu, L. & Raetzman, L. T., Sep 1 2013, In : Development (Cambridge). 140, 17, p. 3511-3521 11 p.

Research output: Contribution to journalArticle

Maintenance
Neurons
body size
loss of function
Body Size
2012

Aryl-hydrocarbon receptor activity modulates prolactin expression in the pituitary

Moran, T. B., Brannick, K. E. & Raetzman, L. T., Nov 15 2012, In : Toxicology and Applied Pharmacology. 265, 1, p. 139-145 7 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Prolactin
Pituitary Hormones
Dioxins
Tumors
hypothyroidism
Hypothyroidism
Dogs
Water
dogs

P21, an important mediator of quiescence during pituitary tumor formation, is dispensable for normal pituitary development during embryogenesis

Monahan, P., Himes, A. D., Parfieniuk, A. & Raetzman, L. T., Jan 1 2012, In : Mechanisms of Development. 128, 11-12, p. 640-652 13 p.

Research output: Contribution to journalArticle

Pituitary Neoplasms
Embryonic Development
Cell Cycle
Cyclin-Dependent Kinase Inhibitor Proteins
Ectoderm

Prenatal exposure to low doses of bisphenol a increases pituitary proliferation and gonadotroph number in female mice offspring at birth

Brannick, K. E., Craig, Z. R., Himes, A. D., Peretz, J. R., Wang, W., Flaws, J. A. & Raetzman, L. T., Oct 1 2012, In : Biology of reproduction. 87, 4, Article 82.

Research output: Contribution to journalArticle

Gonadotrophs
Parturition
Gonadotropins
Hormones
Messenger RNA
2011

N-cadherin loss in POMC-expressing cells leads to pituitary disorganization

Himes, A. D., Fiddler, R. M. & Raetzman, L. T., Mar 1 2011, In : Molecular Endocrinology. 25, 3, p. 482-491 10 p.

Research output: Contribution to journalArticle

Pro-Opiomelanocortin
Cadherins
Pituitary Neoplasms
Intermediate Pituitary Gland
Cell Proliferation

Numb deletion in pomc-expressing cells impairs pituitary intermediate lobe cell adhesion, progenitor cell localization, and neuro-intermediate lobe boundary formation

Moran, T. B., Goldberg, L. B., Serviss, S. L. & Raetzman, L. T., Jan 1 2011, In : Molecular Endocrinology. 25, 1, p. 117-127 11 p.

Research output: Contribution to journalArticle

Intermediate Pituitary Gland
Cell Adhesion
Stem Cells
Cadherins
Adherens Junctions

Persistent expression of activated Notch inhibits corticotrope and melanotrope differentiation and results in dysfunction of the HPA axis

Goldberg, L. B., Aujla, P. K. & Raetzman, L. T., Oct 1 2011, In : Developmental Biology. 358, 1, p. 23-32 10 p.

Research output: Contribution to journalArticle

Intermediate Pituitary Gland
Paraventricular Hypothalamic Nucleus
Adrenal Glands
Corticosterone
Transcription Factors

The Notch effector gene Hes1 regulates migration of hypothalamic neurons, neuropeptide content and axon targeting to the pituitary

Aujla, P. K., Bora, A., Monahan, P., Sweedler, J. V. & Raetzman, L. T., May 1 2011, In : Developmental Biology. 353, 1, p. 61-71 11 p.

Research output: Contribution to journalArticle

Arginine Vasopressin
Neuropeptides
Axons
Supraoptic Nucleus
Paraventricular Hypothalamic Nucleus
2009

Premature differentiation and aberrant movement of pituitary cells lacking both Hes1 and Prop1

Himes, A. D. & Raetzman, L. T., Jan 1 2009, In : Developmental Biology. 325, 1, p. 151-161 11 p.

Research output: Contribution to journalArticle

Cell Movement
Cadherins
Down-Regulation
Gastropoda
Epithelial-Mesenchymal Transition

The notch target gene Hes1 regulates cell cycle inhibitor expression in the developing pituitary

Monahan, P., Rybak, S. & Raetzman, L. T., Sep 1 2009, In : Endocrinology. 150, 9, p. 4386-4394 9 p.

Research output: Contribution to journalArticle

Cell Cycle
Genes
Cyclin-Dependent Kinase Inhibitor p57
Hormones
Cyclin-Dependent Kinase Inhibitor p27
2008

Notch signaling maintains Leydig progenitor cells in the mouse testis

Tang, H., Brennan, J., Karl, J., Hamada, Y., Raetzman, L. & Capel, B., Dec 1 2008, In : Development. 135, 22, p. 3745-3753 9 p.

Research output: Contribution to journalArticle

Leydig Cells
Testis
germ cell
Stem Cells
interstitial

The 88th Annual Meeting of the Endocrine Society, June 24-27, 2006 Boston MA, USA: Selected pediatric presentations

Geffner, M. E., Demay, M., Raetzman, L., Holm, I., Diamanti-Kandarakis, E., Savage, M. O., Francis, G. & Rogol, A. D., Mar 1 2008, In : Pediatric Endocrinology Reviews. 5, 3, p. 789-795 7 p.

Research output: Contribution to journalArticle

Endocrine System Diseases
Endocrinology
Pediatrics
2007

Comparative genomics reveals functional transcriptional control sequences in the Prop1 gene

Ward, R. D., Davis, S. W., Cho, M. C., Esposito, C., Lyons, R. H., Cheng, J. F., Rubin, E. M., Rhodes, S. J., Raetzman, L. T., Smith, T. P. L. & Camper, S. A., Jul 1 2007, In : Mammalian Genome. 18, 6-7, p. 521-537 17 p.

Research output: Contribution to journalArticle

Pituitary Hormones
Genomics
Transgenes
Lemur
Mutation

Hes1 is required for pituitary growth and melanotrope specification

Raetzman, L. T., Cai, J. X. & Camper, S. A., Apr 15 2007, In : Developmental Biology. 304, 2, p. 455-466 12 p.

Research output: Contribution to journalArticle

Growth
Cell Differentiation
Endocrine Cells
Organ Size
Pituitary Gland

The deoxyribonucleic acid repair protein flap endonuclease-1 modulates estrogen-responsive gene expression

Schultz-Norton, J. R., Walt, K. A., Ziegler, Y. S., McLeod, I. X., Yates, J. R., Raetzman, L. T. & Nardulli, A. M., Jul 1 2007, In : Molecular Endocrinology. 21, 7, p. 1569-1580 12 p.

Research output: Contribution to journalArticle

Flap Endonucleases
Estrogen Receptors
Estrogens
Gene Expression
DNA
2006

Cell proliferation and vascularization in mouse models of pituitary hormone deficiency

Ward, R. D., Stone, B. M., Raetzman, L. T. & Camper, S. A., Jun 1 2006, In : Molecular Endocrinology. 20, 6, p. 1378-1390 13 p.

Research output: Contribution to journalArticle

Pituitary Hormones
Cell Proliferation
Hypopituitarism
Apoptosis
Caspase 3

Persistent expression of Notch2 delays gonadotrope differentiation

Raetzman, L. T., Wheeler, B. S., Ross, S. A., Thomas, P. Q. & Camper, S. A., Nov 2006, In : Molecular Endocrinology. 20, 11, p. 2898-2908 11 p.

Research output: Contribution to journalArticle

Stem Cells
Pituitary Gland
Cell Differentiation
Transgenes
Transgenic Mice

Role of prophet of Pit1 (PROP1) in gonadotrope differentiation and puberty

Vesper, A. H., Raetzman, L. T. & Camper, S. A., Apr 1 2006, In : Endocrinology. 147, 4, p. 1654-1663 10 p.

Research output: Contribution to journalArticle

Hypogonadism
Puberty
Transgenic Mice
Early Growth Response Protein 1
Activin Receptors
2005

Role of PROP1 in pituitary gland growth

Ward, R. D., Raetzman, L. T., Suh, H., Stone, B. M., Nasonkin, I. O. & Camper, S. A., Mar 1 2005, In : Molecular Endocrinology. 19, 3, p. 698-710 13 p.

Research output: Contribution to journalArticle

Pituitary Gland
Parturition
Apoptosis
Anterior Pituitary Gland
Organogenesis
2004

Developmental regulation of Notch signaling genes in the embryonic pituitary: Prop1 deficiency affects Notch2 expression

Raetzman, L. T., Ross, S. A., Cook, S., Dunwoodie, S. L., Camper, S. A. & Thomas, P. Q., Jan 15 2004, In : Developmental Biology. 265, 2, p. 329-340 12 p.

Research output: Contribution to journalArticle

Stem Cells
Genes
Cell Differentiation
Cell Lineage
Pituitary Gland
Neuregulins
Neuregulin-1
GABA-A Receptors
Neurons
Rats

Pituitary hypoplasia and respiratory distress syndrome in Prop1 knockout mice

Nasonkin, I. O., Ward, R. D., Raetzman, L. T., Seasholtz, A. F., Saunders, T. L., Gillespie, P. J. & Camper, S. A., Nov 15 2004, In : Human molecular genetics. 13, 22, p. 2727-2735 9 p.

Research output: Contribution to journalArticle

Pituitary Hormones
Knockout Mice
Alleles
Anterior Pituitary Gland
Pulmonary Atelectasis
2001

Persistent Prop1 expression delays gonadotrope differentiation and enhances pituitary tumor susceptibility

Cushman, L. J., Watkins-Chow, D. E., Brinkmeier, M. L., Raetzman, L. T., Radak, A. L., Lloyd, R. V. & Camper, S. A., May 15 2001, In : Human molecular genetics. 10, 11, p. 1141-1153 13 p.

Research output: Contribution to journalArticle

Pituitary Neoplasms
Central Nervous System Cysts
Anterior Pituitary Gland
Hypogonadism
Differentiation Antigens
1999

Immature granule neurons from cerebella of different ages exhibit distinct developmental potentials

Raetzman, L. T. & Siegel, R. E., Jan 1 1999, In : Journal of Neurobiology. 38, 4, p. 559-570 12 p.

Research output: Contribution to journalArticle

Cerebellum
GABA-A Receptors
Neurons
Messenger RNA
Bromodeoxyuridine

Neuregulin induces GABA(A) receptor subunit expression and neurite outgrowth in cerebellar granule cells

Rieff, H. I., Raetzman, L. T., Sapp, D. W., Yeh, H. H., Siegel, R. E. & Corfas, G., Dec 15 1999, In : Journal of Neuroscience. 19, 24, p. 10757-10766 10 p.

Research output: Contribution to journalArticle

Neuregulins
GABA-A Receptors
Brain-Derived Neurotrophic Factor
Cell Culture Techniques
Immunoglobulin Subunits
1996

GABA(A) receptor subunit expression and assembly in cultured rat cerebellar granule neurons

Nadler, L. S., Raetzman, L. T., Dunkle, K. L., Mueller, N. & Siegel, R. E., Dec 23 1996, In : Developmental Brain Research. 97, 2, p. 216-225 10 p.

Research output: Contribution to journalArticle

GABA-A Receptors
Neurons
Peptides
GABA Receptors
Western Blotting