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Research Output

2019

High-intensity focused ultrasound-induced mechanochemical transduction in synthetic elastomers

Kim, G., Lau, V. M., Halmes, A. J., Oelze, M. L., Moore, J. S. & Li, K. C., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 21, p. 10214-10222 9 p.

Research output: Contribution to journalArticle

2017

Alpha particle enhanced blood brain/tumor barrier permeabilization in glioblastomas using integrin alpha-v beta-3–targeted liposomes

Sattiraju, A., Xiong, X., Pandya, D. N., Wadas, T. J., Xuan, A., Sun, Y., Jung, Y., Sai, K. K. S., Dorsey, J. F., Li, K. C. & Mintz, A., Oct 2017, In : Molecular Cancer Therapeutics. 16, 10, p. 2191-2200 10 p.

Research output: Contribution to journalArticle

Enhancing tissue permeability with MRI guided preclinical focused ultrasound system in rabbit muscle: From normal tissue to VX2 tumor

Sun, Y., Xiong, X., Pandya, D., Jung, Y., Mintz, A., Hayasaka, S., Wadas, T. J. & Li, K. C. P., Jun 28 2017, In : Journal of Controlled Release. 256, p. 1-8 8 p.

Research output: Contribution to journalArticle

Phosphatidylserine-targeted nanotheranostics for brain tumor imaging and therapeutic potential

Wang, L., Habib, A. A., Mintz, A., Li, K. C. & Zhao, D., Jan 1 2017, In : Molecular imaging. 16

Research output: Contribution to journalReview article

2016

A systematic approach to predicting spring force for sagittal craniosynostosis surgery

Zhang, G., Tan, H., Qian, X., Zhang, J., Li, K., David, L. R. & Zhou, X., Jan 1 2016, In : Journal of Craniofacial Surgery. 27, 3, p. 636-643 8 p.

Research output: Contribution to journalArticle

A systematic approach to predicting the risk of unicompartmental knee arthroplasty revision

Zhang, G., Smith, B. P., Plate, J. F., Casanova, R., Hsu, F. C., Li, J., Xia, L., Li, K. C., Poehling, G. G. & Zhou, X., Jun 1 2016, In : Osteoarthritis and Cartilage. 24, 6, p. 991-999 9 p.

Research output: Contribution to journalArticle

Prediction of treatment efficacy for prostate cancer using a mathematical model

Peng, H., Zhao, W., Tan, H., Ji, Z., Li, J., Li, K. & Zhou, X., Feb 12 2016, In : Scientific reports. 6, 21599.

Research output: Contribution to journalArticle

Preliminary therapy evaluation of 225Ac-DOTA-c (RGDyK) demonstrates that Cerenkov radiation derived from 225Ac daughter decay can be detected by optical imaging for in vivo tumor visualization

Pandya, D. N., Hantgan, R., Budzevich, M. M., Kock, N. D., Morse, D. L., Batista, I., Mintz, A., Li, K. C. & Wadas, T. J., Mar 1 2016, In : Theranostics. 6, 5, p. 698-709 12 p.

Research output: Contribution to journalArticle

Pseudo progression identification of glioblastoma with dictionary learning

Zhang, J., Yu, H., Qian, X., Liu, K., Tan, H., Yang, T., Wang, M., Li, K. C., Chan, M. D., Debinski, W., Paulsson, A., Wang, G. & Zhou, X., Jun 1 2016, In : Computers in Biology and Medicine. 73, p. 94-101 8 p.

Research output: Contribution to journalArticle

2015

Multi-scale modeling for the transmission of influenza and the evaluation of interventions toward it

Guo, D., Li, K. C., Peters, T. R., Snively, B. M., Poehling, K. A. & Zhou, X., Mar 11 2015, In : Scientific reports. 5, 8980.

Research output: Contribution to journalArticle

Objective classification system for sagittal craniosynostosis based on suture segmentation

Qian, X., Tan, H., Zhang, J., Zhuang, X., Branch, L., Sanger, C., Thompson, A., Zhao, W., Li, K. C., David, L. & Zhou, X., Sep 1 2015, In : Medical Physics. 42, 9, p. 5545-5558 14 p.

Research output: Contribution to journalArticle

Remote spatiotemporally controlled and biologically selective permeabilization of blood-brain barrier

Xiong, X., Sun, Y., Sattiraju, A., Jung, Y., Mintz, A., Hayasaka, S. & Li, K. C. P., Nov 10 2015, In : Journal of Controlled Release. 217, p. 113-120 8 p., 7824.

Research output: Contribution to journalArticle

Systems biology approach to studying proliferation-dependent prognostic subnetworks in breast cancer

Song, Q., Wang, H., Bao, J., Pullikuth, A. K., Li, K. C., Miller, L. D. & Zhou, X., Aug 10 2015, In : Scientific reports. 5, 12981.

Research output: Contribution to journalArticle

2014

Computational modeling of 3D tumor growth and angiogenesis for chemotherapy evaluation

Tang, L., Van De Ven, A. L., Guo, D., Andasari, V., Cristini, V., Li, K. C. & Zhou, X., Jan 3 2014, In : PloS one. 9, 1, e83962.

Research output: Contribution to journalArticle

In vivo MRI detection of carotid atherosclerotic lesions and kidney inflammation in ApoE-deficient mice by using LOX-1 targeted iron nanoparticles

Wen, S., Liu, D. F., Cui, Y., Harris, S. S., Chen, Y. C., Li, K. C., Ju, S. H. & Teng, G. J., Apr 2014, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 10, 3, p. 639-649 11 p.

Research output: Contribution to journalArticle

Near-infrared fluorescence imaging of murine atherosclerosis using an oxidized low density lipoprotein-targeted fluorochrome

Lu, T., Wen, S., Cui, Y., Ju, S. H., Li, K. C. & Teng, G. J., Jan 2014, In : International Journal of Cardiovascular Imaging. 30, 1, p. 221-231 11 p.

Research output: Contribution to journalArticle

Tumor lysing genetically engineered t cells loaded with multi-modal imaging agents

Bhatnagar, P., Alauddin, M., Bankson, J. A., Kirui, D., Seifi, P., Huls, H., Lee, D. A., Babakhani, A., Ferrari, M., Li, K. C. & Cooper, L. J. N., Mar 28 2014, In : Scientific reports. 4, 4502.

Research output: Contribution to journalArticle

2013

A system mathematical model of a cell-cell communication network in amyotrophic lateral sclerosis

Shao, H., He, Y., Li, K. C. P. & Zhou, X., Mar 1 2013, In : Molecular BioSystems. 9, 3, p. 398-406 9 p.

Research output: Contribution to journalArticle

Digitization of Medicine: How Radiology Can Take Advantage of the Digital Revolution

Li, K. C., Marcovici, P., Phelps, A., Potter, C., Tillack, A., Tomich, J. & Tridandapani, S., Dec 1 2013, In : Academic Radiology. 20, 12, p. 1479-1494 16 p.

Research output: Contribution to journalReview article

Imaging of genetically engineered T cells by PET using gold nanoparticles complexed to Copper-64

Bhatnagar, P., Li, Z., Choi, Y., Guo, J., Li, F., Lee, D. Y., Figliola, M., Huls, H., Lee, D. A., Zal, T., Li, K. C. & Cooper, L. J. N., Jan 2013, In : Integrative Biology (United Kingdom). 5, 1, p. 231-238 8 p.

Research output: Contribution to journalArticle

MRI-based prediction of pulsed high-intensity focused ultrasound effect on tissue transport in rabbit muscle

O'Neill, B. E., Vo, H. Q., Shao, H., Karmonik, C., Zhou, X. & Li, K. C., Nov 1 2013, In : Journal of Magnetic Resonance Imaging. 38, 5, p. 1094-1102 9 p.

Research output: Contribution to journalArticle

Multispectral photoacoustic imaging of tissue denaturation induced by high-intensity focused ultrasound treatment

Sun, Y., Li, K. C. & O'Neill, B., May 28 2013, Photons Plus Ultrasound: Imaging and Sensing 2013. 85813H. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 8581).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Multivalency of non-peptide integrin αvβ3 antagonist slows tumor growth

Kim, Y. S., Li, F., Kong, R., Bai, Y., Li, K. C. P., Fan, Y., O'Neill, B. E. & Li, Z., Oct 7 2013, In : Molecular pharmaceutics. 10, 10, p. 3603-3611 9 p.

Research output: Contribution to journalArticle

Photoacoustic imaging in the evaluation of laser controlled drug release using gold nanostructure agents

Sun, Y., Li, K. C. P. & O'Neill, B., May 28 2013, Photons Plus Ultrasound: Imaging and Sensing 2013. 85813F. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 8581).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Radiology Research Alliance. Why All Radiology Researchers Should Join

Li, K. C., Dec 1 2013, In : Academic Radiology. 20, 12, p. 1477-1478 2 p.

Research output: Contribution to journalEditorial

Synthesis and evaluation of an imidazole derivative-fluorescein conjugate

Ghosh, P., Zhang, J., Shi, Z. Z. & Li, K., Apr 15 2013, In : Bioorganic and Medicinal Chemistry. 21, 8, p. 2418-2425 8 p.

Research output: Contribution to journalArticle

Systems Modeling of Anti-apoptotic Pathways in Prostate Cancer: Psychological Stress Triggers a Synergism Pattern Switch in Drug Combination Therapy

Sun, X., Bao, J., Nelson, K. C., Li, K. C., Kulik, G. & Zhou, X., Dec 1 2013, In : PLoS computational biology. 9, 12, e1003358.

Research output: Contribution to journalArticle

2012

Enhanced MRI relaxivity of Gd3+-based contrast agents geometrically confined within porous nanoconstructs

Sethi, R., Ananta, J. S., Karmonik, C., Zhong, M., Fung, S. H., Liu, X., Li, K., Ferrari, M., Wilson, L. J. & Decuzzi, P., Nov 1 2012, In : Contrast Media and Molecular Imaging. 7, 6, p. 501-508 8 p.

Research output: Contribution to journalArticle

Estimation of thermal dose from MR thermometry during application of nonablative pulsed high intensity focused ultrasound

O'Neill, B. E., Karmonik, C., Sassaroli, E. & Li, K. C., May 1 2012, In : Journal of Magnetic Resonance Imaging. 35, 5, p. 1169-1178 10 p.

Research output: Contribution to journalArticle

Modeling focused ultrasound exposure for the optimal control of thermal dose distribution

Sassaroli, E., Li, K. C. P. & O'Neill, B. E., May 21 2012, In : The Scientific World Journal. 2012, 252741.

Research output: Contribution to journalArticle

Multimodality theranostics and molecular imaging in the diagnosis and treatment of lung cancer

Raparia, K., Wong, K., Wong, S., Li, K. C. & Cagle, P. T., Mar 28 2012, Advances in Surgical Pathology: Lung Cancer. Wolters Kluwer Health Adis (ESP), p. 271-280 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Radio frequency absorption in gold nanoparticle suspensions: A phenomenological study

Sassaroli, E., Li, K. C. P. & O'Neill, B. E., Feb 22 2012, In : Journal of Physics D: Applied Physics. 45, 7, 075303.

Research output: Contribution to journalArticle

2011

Biomarker motif discovery by integrating mass spectrometry and PPI network

Zhou, X., Wang, Y., Wang, H., Pham, T. D. & Li, K., Jul 13 2011, 2011 International Symposium on Computational Models for Life Sciences, CMLS-11. p. 225-233 9 p. (AIP Conference Proceedings; vol. 1371).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Molecular theranostics: A primer for the imaging professional

Lee, D. Y. & Li, K. C. P., Aug 1 2011, In : American Journal of Roentgenology. 197, 2, p. 318-324 7 p.

Research output: Contribution to journalReview article

Partially polymerized liposomes: Stable against leakage yet capable of instantaneous release for remote controlled drug delivery

Qin, G., Li, Z., Xia, R., Li, F., O'Neill, B. E., Goodwin, J. T., Khant, H. A., Chiu, W. & Li, K. C., Apr 15 2011, In : Nanotechnology. 22, 15, 155605.

Research output: Contribution to journalArticle

Radiosynthesis of [ 18F]fluoromethyldeoxyspergualin for molecular imaging of heat shock proteins

Ghosh, P., Li, K. C. & Lee, D. Y., Mar 1 2011, In : Applied Radiation and Isotopes. 69, 3, p. 609-613 5 p.

Research output: Contribution to journalArticle

Stem cell tracking. A perfect application for multimodality imaging

Li, K. C., Jan 1 2011, In : Academic Radiology. 18, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

2010

99mTc-labeling of peptidomimetic antagonist to selectively target αvβ3 receptor-positive tumor: Comparison of PDA and EEDA as co-ligands

Shin, I. S., Maeng, J. S., Jang, B. S., You, E., Cheng, K., Li, K. C. P., Wood, B., Carrasquillo, J. A., Danthi, S. N. & Paik, C. H., Jul 12 2010, In : Current Radiopharmaceuticals. 3, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

An optimum method for pulsed high intensity focused ultrasound treatment of large volumes using the InSightec ExAblate® 2000 system

O'Neill, B. E., Karmonik, C. & Li, K. C. P., Nov 7 2010, In : Physics in medicine and biology. 55, 21, p. 6395-6410 16 p.

Research output: Contribution to journalArticle

"clickable", polymerized liposomes as a versatile and stable platform for rapid optimization of their peripheral compositions

Kumar, A., Erasquin, U. J., Qin, G., Li, K. & Cai, C., Aug 21 2010, In : Chemical Communications. 46, 31, p. 5746-5748 3 p.

Research output: Contribution to journalArticle

Combining gene therapy and nanomedicine to enhance the therapeutic potential of T cells

Choi, Y., Torikai, H., Lee, D. Y., Li, Z., Lo, D., Qin, G., Tung, C. H., Tasciotti, E., Raphael, R., Biswal, S. L., Ang, S., Lee, D. A., Li, K. C. & Cooper, L. J. N., Nov 9 2010, Nanotechnology 2010: Bio Sensors, Instruments, Medical, Environment and Energy - Technical Proceedings of the 2010 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2010. p. 376-379 4 p. (Nanotechnology 2010: Bio Sensors, Instruments, Medical, Environment and Energy - Technical Proceedings of the 2010 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2010; vol. 3).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Synthesis and evaluation of a near-infrared fluorescent non-peptidic bivalent integrin αvβ3 antagonist for cancer imaging

Li, F., Liu, J., Jas, G. S., Zhang, J., Qin, G., Xing, J., Cotes, C., Zhao, H., Wang, X., Diaz, L. A., Shi, Z. Z., Lee, D. Y., Li, K. C. P. & Li, Z., Feb 17 2010, In : Bioconjugate Chemistry. 21, 2, p. 270-278 9 p.

Research output: Contribution to journalArticle

Synthesis and evaluation of bivalent, peptidomimetic antagonists of the αvβ3 integrins

Li, F., Jas, G. S., Qin, G., Li, K. & Li, Z., Nov 15 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 22, p. 6577-6580 4 p.

Research output: Contribution to journalArticle

2009

Acoustic fingerprints of dye-labeled protein submicrosphere photoacoustic contrast agents

McDonald, M. A., Jankovic, L., Shahzad, K., Burcher, M. & Li, K. C. P., Dec 1 2009, In : Journal of biomedical optics. 14, 3, 034032.

Research output: Contribution to journalArticle

From molecular imaging to systems diagnostics: Time for another paradigm shift?

Li, K. C. P., May 1 2009, In : European Journal of Radiology. 70, 2, p. 201-204 4 p.

Research output: Contribution to journalArticle

Identification of biomarkers for risk stratification of cardiovascular events using genetic algorithm with recursive local floating search

Zhou, X., Wang, H., Wang, J., Wang, Y., Hoehn, G., Azok, J., Brennan, M. L., Hazen, S. L., Li, K., Chang, S. F. & Wong, S. T. C., Apr 1 2009, In : Proteomics. 9, 8, p. 2286-2294 9 p.

Research output: Contribution to journalArticle

Linear behavior of a preformed microbubble containing light absorbing nanoparticles: Insight from a mathematical model

Sassaroli, E., Li, K. C. P. & O'Neill, B. E., Nov 17 2009, In : Journal of the Acoustical Society of America. 126, 5, p. 2802-2813 12 p.

Research output: Contribution to journalArticle

Numerical investgation of the laser heating of gold nanoparticles Including thermal and dielectric changes in the local medium

Sassaroli, E., O'Neill, B. E. & Li, K. C. P., Nov 17 2009, Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009. p. 763-766 4 p. 5193161. (Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Numerical investigation of heating of a gold nanoparticle and the surrounding microenvironment by nanosecond laser pulses for nanomedicine applications

Sassaroli, E., Li, K. C. & O'Neill, B. E., Nov 9 2009, In : Physics in medicine and biology. 54, 18, p. 5541-5560 20 p.

Research output: Contribution to journalArticle