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Search results

  • 2021

    BRD4 inhibition and FXR activation, individually beneficial in cholestasis, are antagonistic in combination

    Jung, H., Chen, J., Hu, X., Sun, H., Wu, S. Y., Chiang, C. M., Kemper, B., Chen, L. F. & Kemper, J. K., Jan 11 2021, In: JCI Insight. 6, 1, e141640.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • 2020

    Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase

    Byun, S., Seok, S., Kim, Y. C., Zhang, Y., Yau, P., Iwamori, N., Xu, H. E., Ma, J., Kemper, B. & Kemper, J. K., Dec 1 2020, In: Nature communications. 11, 1, 807.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Intestinal FGF15/19 physiologically repress hepatic lipogenesis in the late fed-state by activating SHP and DNMT3A

    Kim, Y-C., Seok, S., Zhang, Y., Ma, J., Kong, B., Guo, G., Kemper, B. & Kemper, J. K., Dec 2020, In: Nature communications. 11, 1, 5969.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • MicroRNA-210 Promotes Bile Acid–Induced Cholestatic Liver Injury by Targeting Mixed-Lineage Leukemia-4 Methyltransferase in Mice

    Kim, Y. C., Jung, H., Seok, S., Zhang, Y., Ma, J., Li, T., Kemper, B. & Kemper, J. K., Jun 1 2020, In: Hepatology. 71, 6, p. 2118-2134 17 p.

    Research output: Contribution to journalArticlepeer-review

  • 2019

    Phosphorylation of hepatic farnesoid X receptor by FGF19 signaling–activated Src maintains cholesterol levels and protects from atherosclerosis

    Byun, S., Jung, H., Chen, J., Kim, Y. C., Kim, D. H., Kong, B., Guo, G., Kemper, B. & Kemper, J. K., May 31 2019, In: Journal of Biological Chemistry. 294, 22, p. 8732-8744 13 p.

    Research output: Contribution to journalArticlepeer-review

  • Small Heterodimer Partner and Fibroblast Growth Factor 19 Inhibit Expression of NPC1L1 in Mouse Intestine and Cholesterol Absorption

    Kim, Y. C., Byun, S., Seok, S., Guo, G., Xu, H. E., Kemper, B. & Kemper, J. K., Mar 2019, In: Gastroenterology. 156, 4, p. 1052-1065 14 p.

    Research output: Contribution to journalArticlepeer-review

  • Small Heterodimer Partner Regulates Dichotomous T Cell Expansion by Macrophages

    Shahoei, S. H., Kim, Y. C., Cler, S. J., Ma, L., Anakk, S., Kemper, J. K. & Nelson, E. R., 2019, In: Endocrinology. 160, 7, p. 1573-1589 17 p.

    Research output: Contribution to journalArticlepeer-review

  • 2018

    AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle

    Kim, Y. C., Seok, S., Byun, S., Kong, B., Zhang, Y., Guo, G., Xie, W., Ma, J., Kemper, B. & Kemper, J. K., Dec 1 2018, In: Nature communications. 9, 1, 540.

    Research output: Contribution to journalArticlepeer-review

  • Fasting-induced JMJD3 histone demethylase epigenetically activates mitochondrial fatty acid ß-oxidation

    Seok, S., Kim, Y. C., Byun, S., Choi, S., Xiao, Z., Iwamori, N., Zhang, Y., Wang, C., Ma, J., Ge, K., Kemper, B. & Kemper, J. K., Jul 2 2018, In: Journal of Clinical Investigation. 128, 7, p. 3144-3159 16 p.

    Research output: Contribution to journalArticlepeer-review

  • Postprandial FGF19-induced phosphorylation by Src is critical for FXR function in bile acid homeostasis

    Byun, S., Kim, D. H., Ryerson, D., Kim, Y. C., Sun, H., Kong, B., Yau, P., Guo, G., Eric Xu, H., Kemper, B. & Kemper, J. K., Dec 1 2018, In: Nature communications. 9, 1, 2590.

    Research output: Contribution to journalArticlepeer-review

  • 2017

    A postprandial FGF19-SHP-LSD1 regulatory axis mediates epigenetic repression of hepatic autophagy

    Byun, S., Kim, Y. C., Zhang, Y., Kong, B., Guo, G., Sadoshima, J., Ma, J., Kemper, B. & Kemper, J. K., Jun 14 2017, In: EMBO Journal. 36, 12, p. 1755-1769 15 p.

    Research output: Contribution to journalArticlepeer-review

  • Obesity-linked phosphorylation of SIRT1 by casein kinase 2 inhibits its nuclear localization and promotes fatty liver

    Choi, S. E., Kwon, S., Seok, S., Xiao, Z., Lee, K. W., Kang, Y., Li, X., Shinoda, K., Kajimura, S., Kemper, B. & Kemper, J. K., Aug 1 2017, In: Molecular and cellular biology. 37, 15, e00006-17.

    Research output: Contribution to journalArticlepeer-review

  • The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells

    Baek, A. E., Yu, Y. R. A., He, S., Wardell, S. E., Chang, C. Y., Kwon, S., Pillai, R. V., McDowell, H. B., Thompson, J. W., Dubois, L. G., Sullivan, P. M., Kemper, J. K., Gunn, M. D., McDonnell, D. P. & Nelson, E. R., Dec 1 2017, In: Nature communications. 8, 1, 864.

    Research output: Contribution to journalArticlepeer-review

  • 2016

    Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis

    Kim, D. H., Kwon, S., Byun, S., Xiao, Z., Park, S., Wu, S. Y., Chiang, C. M., Kemper, B. & Kemper, J. K., Jul 14 2016, In: Nature communications. 7, 12179.

    Research output: Contribution to journalArticlepeer-review

  • FXR primes the liver for intestinal FGF15 signaling by transient induction of β-Klotho

    Fu, T., Kim, Y. C., Byun, S., Kim, D. H., Seok, S., Suino-Powell, K., Eric Xu, H., Kemper, B. & Kemper, J. K., Jan 2016, In: Molecular Endocrinology. 30, 1, p. 92-103 12 p.

    Research output: Contribution to journalArticlepeer-review

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Arozena, A. A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., Adhihetty, P. J., Adler, S. G., Agam, G., Agarwal, R., Aghi, M. K., Agnello, M., Agostinis, P., Aguilar, P. V., Aguirre-Ghiso, J., Airoldi, E. M. & 2,442 others, Ait-Si-Ali, S., Akematsu, T., Akporiaye, E. T., Al-Rubeai, M., Albaiceta, G. M., Albanese, C., Albani, D., Albert, M. L., Aldudo, J., Algül, H., Alirezaei, M., Alloza, I., Almasan, A., Almonte-Beceril, M., Alnemri, E. S., Alonso, C., Altan-Bonnet, N., Altieri, D. C., Alvarez, S., Alvarez-Erviti, L., Alves, S., Amadoro, G., Amano, A., Amantini, C., Ambrosio, S., Amelio, I., Amer, A. O., Amessou, M., Amon, A., An, Z., Anania, F. A., Andersen, S. U., Andley, U. P., Andreadi, C. K., Andrieu-Abadie, N., Anel, A., Ann, D. K., Anoopkumar-Dukie, S., Antonioli, M., Aoki, H., Apostolova, N., Aquila, S., Aquilano, K., Araki, K., Arama, E., Aranda, A., Araya, J., Arcaro, A., Arias, E., Arimoto, H., Ariosa, A. R., Armstrong, J. L., Arnould, T., Arsov, I., Asanuma, K., Askanas, V., Asselin, E., Atarashi, R., Atherton, S. S., Atkin, J. D., Attardi, L. D., Auberger, P., Auburger, G., Aurelian, L., Autelli, R., Avagliano, L., Avantaggiati, M. L., Avrahami, L., Azad, N., Awale, S., Bachetti, T., Backer, J. M., Bae, D. H., Bae, J. S., Bae, O. N., Bae, S. H., Baehrecke, E. H., Baek, S. H., Baghdiguian, S., Bagniewska-Zadworna, A., Bai, H., Bai, J., Bai, X. Y., Bailly, Y., Balaji, K. N., Balduini, W., Ballabio, A., Balzan, R., Banerjee, R., Bánhegyi, G., Bao, H., Barbeau, B., Barrachina, M. D., Barreiro, E., Bartel, B., Bartolomé, A., Bassham, D. C., Bassi, M. T., Bast, R. C., Basu, A., Batista, M. T., Batoko, H., Battino, M., Bauckman, K., Baumgarner, B. L., Bayer, K. U., Beale, R., Beaulieu, J. F., Beck, G. R., Becker, C., Beckham, J. D., Bédard, P. A., Bednarski, P. J., Begley, T. J., Behl, C., Behrends, C., Behrens, G. M. N., Behrns, K. E., Bejarano, E., Belaid, A., Belleudi, F., Bénard, G., Berchem, G., Bergamaschi, D., Bergami, M., Berkhout, B., Berliocchi, L., Bernard, A., Bernard, M., Bernassola, F., Bertolotti, A., Bess, A. S., Besteiro, S., Bettuzzi, S., Bhalla, S., Bhattacharyya, S., Bhutia, S. K., Biagosch, C., Bianchi, M. W., Biard-Piechaczyk, M., Billes, V., Bincoletto, C., Bingol, B., Bird, S. W., Bitoun, M., Bjedov, I., Blackstone, C., Blanc, L., Blanco, G. A., Blomhoff, H. K., Boada-Romero, E., Böckler, S., Boes, M., Boesze-Battaglia, K., Boise, L. H., Bolino, A., Boman, A., Bonaldo, P., Bordi, M., Bosch, J., Botana, L. M., Botti, J., Bou, G., Bouché, M., Bouchecareilh, M., Boucher, M. J., Boulton, M. E., Bouret, S. G., Boya, P., Boyer-Guittaut, M., Bozhkov, P. V., Brady, N., Braga, V. M. M., Brancolini, C., Braus, G. H., Bravo-San-Pedro, J. M., Brennan, L. A., Bresnick, E. H., Brest, P., Bridges, D., Bringer, M. A., Brini, M., Brito, G. C., Brodin, B., Brookes, P. S., Brown, E. J., Brown, K., Broxmeyer, H. E., Bruhat, A., Brum, P. C., Brumell, J. H., Brunetti-Pierri, N., Bryson-Richardson, R. J., Buch, S., Buchan, A. M., Budak, H., Bulavin, D. V., Bultman, S. J., Bultynck, G., Bumbasirevic, V., Burelle, Y., Burke, R. E., Burmeister, M., Bütikofer, P., Caberlotto, L., Cadwell, K., Cahova, M., Cai, D., Cai, J., Cai, Q., Calatayud, S., Camougrand, N., Campanella, M., Campbell, G. R., Campbell, M., Campello, S., Candau, R., Caniggia, I., Cantoni, L., Cao, L., Caplan, A. B., Caraglia, M., Cardinali, C., Cardoso, S. M., Carew, J. S., Carleton, L. A., Carlin, C. R., Carloni, S., Carlsson, S. R., Carmona-Gutierrez, D., Carneiro, L. A. M., Carnevali, O., Carra, S., Carrier, A., Carroll, B., Casas, C., Casas, J., Cassinelli, G., Castets, P., Castro-Obregon, S., Cavallini, G., Ceccherini, I., Cecconi, F., Cederbaum, A. I., Ceña, V., Cenci, S., Cerella, C., Cervia, D., Cetrullo, S., Chaachouay, H., Chae, H. J., Chagin, A. S., Chai, C. Y., Chakrabarti, G., Chamilos, G., Chan, E. Y. W., Chan, M. T. V., Chandra, D., Chandra, P., Chang, C. P., Chang, R. C. C., Chang, T. Y., Chatham, J. C., Chatterjee, S., Chauhan, S., Che, Y., Cheetham, M. E., Cheluvappa, R., Chen, C. J., Chen, G., Chen, G. C., Chen, G., Chen, H., Chen, J. W., Chen, J. K., Chen, M., Chen, M., Chen, P., Chen, Q., Chen, Q., Chen, S. D., Chen, S., Chen, S. S. L., Chen, W., Chen, W. J., Chen, W. Q., Chen, W., Chen, X., Chen, Y. H., Chen, Y. G., Chen, Y., Chen, Y., Chen, Y., Chen, Y. J., Chen, Y. Q., Chen, Y., Chen, Z., Chen, Z., Cheng, A., Cheng, C. H. K., Cheng, H., Cheong, H., Cherry, S., Chesney, J., Cheung, C. H. A., Chevet, E., Chi, H. C., Chi, S. G., Chiacchiera, F., Chiang, H. L., Chiarelli, R., Chiariello, M., Chieppa, M., Chin, L. S., Chiong, M., Chiu, G. N. C., Cho, D. H., Cho, S. G., Cho, W. C., Cho, Y. Y., Cho, Y. S., Choi, A. M. K., Choi, E. J., Choi, E. K., Choi, J., Choi, M. E., Choi, S. I., Chou, T. F., Chouaib, S., Choubey, D., Choubey, V., Chow, K. C., Chowdhury, K., Chu, C. T., Chuang, T. H., Chun, T., Chung, H., Chung, T., Chung, Y. L., Chwae, Y. J., Cianfanelli, V., Ciarcia, R., Ciechomska, I. A., Ciriolo, M. R., Cirone, M., Claerhout, S., Clague, M. J., Clària, J., Clarke, P. G. H., Clarke, R., Clementi, E., Cleyrat, C., Cnop, M., Coccia, E. M., Cocco, T., Codogno, P., Coers, J., Cohen, E. E. W., Colecchia, D., Coletto, L., Coll, N. S., Colucci-Guyon, E., Comincini, S., Condello, M., Cook, K. L., Coombs, G. H., Cooper, C. D., Cooper, J. M., Coppens, I., Corasaniti, M. T., Corazzari, M., Corbalan, R., Corcelle-Termeau, E., Cordero, M. D., Corral-Ramos, C., Corti, O., Cossarizza, A., Costelli, P., Costes, S., Cotman, S. L., Coto-Montes, A., Cottet, S., Couve, E., Covey, L. R., Cowart, L. A., Cox, J. S., Coxon, F. P., Coyne, C. B., Cragg, M. S., Craven, R. J., Crepaldi, T., Crespo, J. L., Criollo, A., Crippa, V., Cruz, M. T., Cuervo, A. M., Cuezva, J. M., Cui, T., Cutillas, P. R., Czaja, M. J., Czyzyk-Krzeska, M. F., Dagda, R. K., Dahmen, U., Dai, C., Dai, W., Dai, Y., Dalby, K. N., Valle, L. D., Dalmasso, G., D'amelio, M., Damme, M., Darfeuille-Michaud, A., Dargemont, C., Darley-Usmar, V. M., Dasarathy, S., Dasgupta, B., Dash, S., Dass, C. R., Davey, H. M., Davids, L. M., Dávila, D., Davis, R. J., Dawson, T. M., Dawson, V. L., Daza, P., de Belleroche, J., de Figueiredo, P., de Figueiredo, R. C. B. Q., de la Fuente, J., De Martino, L., De Matteis, A., De Meyer, G. R. Y., De Milito, A., De Santi, M., de Souza, W., De Tata, V., De Zio, D., Debnath, J., Dechant, R., Decuypere, J. P., Deegan, S., Dehay, B., Del Bello, B., Del Re, D. P., Delage-Mourroux, R., Delbridge, L. M. D., Deldicque, L., Delorme-Axford, E., Deng, Y., Dengjel, J., Denizot, M., Dent, P., Der, C. J., Deretic, V., Derrien, B., Deutsch, E., Devarenne, T. P., Devenish, R. J., Di Bartolomeo, S., Di Daniele, N., Di Domenico, F., Di Nardo, A., Di Paola, S., Di Pietro, A., Di Renzo, L., Di Antonio, A., Díaz-Araya, G., Díaz-Laviada, I., Diaz-Meco, M. T., Diaz-Nido, J., Dickey, C. A., Dickson, R. C., Diederich, M., Digard, P., Dikic, I., Dinesh-Kumar, S. P., Ding, C., Ding, W. X., Ding, Z., Dini, L., Distler, J. H. W., Diwan, A., Djavaheri-Mergny, M., Dmytruk, K., Dobson, R. C. J., Doetsch, V., Dokladny, K., Dokudovskaya, S., Donadelli, M., Dong, X. C., Dong, X., Dong, Z., Donohue, T. M., Donohue-Jr, T. M., Doran, K. S., D'orazi, G., Dorn, G. W., Dosenko, V., Dridi, S., Drucker, L., Du, J., Du, L. L., Du, L., du Toit, A., Dua, P., Duan, L., Duann, P., Dubey, V. K., Duchen, M. R., Duchosal, M. A., Duez, H., Dugail, I., Dumit, V. I., Duncan, M. C., Dunlop, E. A., Dunn, W. A., Dupont, N., Dupuis, L., Durán, R. V., Durcan, T. M., Duvezin-Caubet, S., Duvvuri, U., Eapen, V., Ebrahimi-Fakhari, D., Echard, A., Eckhart, L., Edelstein, C. L., Edinger, A. L., Eichinger, L., Eisenberg, T., Eisenberg-Lerner, A., Eissa, N. T., El-Deiry, W. S., El-Khoury, V., Elazar, Z., Eldar-Finkelman, H., Elliott, C. J. H., Emanuele, E., Emmenegger, U., Engedal, N., Engelbrecht, A. M., Engelender, S., Enserink, J. M., Erdmann, R., Erenpreisa, J., Eri, R., Eriksen, J. L., Erman, A., Escalante, R., Eskelinen, E. L., Espert, L., Esteban-Martínez, L., Evans, T. J., Fabri, M., Fabrias, G., Fabrizi, C., Facchiano, A., Færgeman, N. J., Faggioni, A., Fairlie, W. D., Fan, C., Fan, D., Fan, J., Fang, S., Fanto, M., Fanzani, A., Farkas, T., Faure, M., Favier, F. B., Fearnhead, H., Federici, M., Fei, E., Felizardo, T. C., Feng, H., Feng, Y., Feng, Y., Ferguson, T. A., Fernández, Á. F., Fernandez-Barrena, M. G., Fernandez-Checa, J. C., Fernández-López, A., Fernandez-Zapico, M. E., Feron, O., Ferraro, E., Ferreira-Halder, C. V., Fesus, L., Feuer, R., Fiesel, F. C., Filippi-Chiela, E. C., Filomeni, G., Fimia, G. M., Fingert, J. H., Finkbeiner, S., Finkel, T., Fiorito, F., Fisher, P. B., Flajolet, M., Flamigni, F., Florey, O., Florio, S., Floto, R. A., Folini, M., Follo, C., Fon, E. A., Fornai, F., Fortunato, F., Fraldi, A., Franco, R., Francois, A., François, A., Frankel, L. B., Fraser, I. D. C., Frey, N., Freyssenet, D. G., Frezza, C., Friedman, S. L., Frigo, D. E., Fu, D., Fuentes, J. M., Fueyo, J., Fujitani, Y., Fujiwara, Y., Fujiya, M., Fukuda, M., Fulda, S., Fusco, C., Gabryel, B., Gaestel, M., Gailly, P., Gajewska, M., Galadari, S., Galili, G., Galindo, I., Galindo, M. F., Galliciotti, G., Galluzzi, L., Galluzzi, L., Galy, V., Gammoh, N., Gandy, S., Ganesan, A. K., Ganesan, S., Ganley, I. G., Gannagé, M., Gao, F. B., Gao, F., Gao, J. X., Nannig, L. G., Véscovi, E. G., Garcia-Macía, M., Garcia-Ruiz, C., Garg, A. D., Garg, P. K., Gargini, R., Gassen, N. C., Gatica, D., Gatti, E., Gavard, J., Gavathiotis, E., Ge, L., Ge, P., Ge, S., Gean, P. W., Gelmetti, V., Genazzani, A. A., Geng, J., Genschik, P., Gerner, L., Gestwicki, J. E., Gewirtz, D. A., Ghavami, S., Ghigo, E., Ghosh, D., Giammarioli, A. M., Giampieri, F., Giampietri, C., Giatromanolaki, A., Gibbings, D. J., Gibellini, L., Gibson, S. B., Ginet, V., Giordano, A., Giorgini, F., Giovannetti, E., Girardin, S. E., Gispert, S., Giuliano, S., Gladson, C. L., Glavic, A., Gleave, M., Godefroy, N., Gogal, R. M., Gokulan, K., Goldman, G. H., Goletti, D., Goligorsky, M. S., Gomes, A. V., Gomes, L. C., Gomez, H., Gomez-Manzano, C., Gómez-Sánchez, R., Gonçalves, D. A. P., Goncu, E., Gong, Q., Gongora, C., Gonzalez, C. B., Gonzalez-Alegre, P., Gonzalez-Cabo, P., González-Polo, R. A., Goping, I. S., Gorbea, C., Gorbunov, N. V., Goring, D. R., Gorman, A. M., Gorski, S. M., Goruppi, S., Goto-Yamada, S., Gotor, C., Gottlieb, R. A., Gozes, I., Gozuacik, D., Graba, Y., Graef, M., Granato, G. E., Grant, G. D., Grant, S., Gravina, G. L., Green, D. R., Greenhough, A., Greenwood, M. T., Grimaldi, B., Gros, F., Grose, C., Groulx, J. F., Gruber, F., Grumati, P., Grune, T., Guan, J. L., Guan, K. L., Guerra, B., Guillen, C., Gulshan, K., Gunst, J., Guo, C., Guo, L., Guo, M., Guo, W., Guo, X. G., Gust, A. A., Gustafsson, Å. B., Gutierrez, E., Gutierrez, M. G., Gwak, H. S., Haas, A., Haber, J. E., Hadano, S., Hagedorn, M., Hahn, D. R., Halayko, A. J., Hamacher-Brady, A., Hamada, K., Hamai, A., Hamann, A., Hamasaki, M., Hamer, I., Hamid, Q., Hammond, E. M., Han, F., Han, W., Handa, J. T., Hanover, J. A., Hansen, M., Harada, M., Harhaji-Trajkovic, L., Harper, J. W., Harrath, A. H., Harris, A. L., Harris, J., Hasler, U., Hasselblatt, P., Hasui, K., Hawley, R. G., Hawley, T. S., He, C., He, C. Y., He, F., He, G., He, R. R., He, X. H., He, Y. W., He, Y. Y., Heath, J. K., Hébert, M. J., Heinzen, R. A., Helgason, G. V., Hensel, M., Henske, E. P., Her, C., Herman, P. K., Hernández, A., Hernandez, C., Hernández-Tiedra, S., Hetz, C., Hiesinger, P. R., Higaki, K., Hilfiker, S., Hill, B. G., Hill, J. A., Hill, W. D., Hino, K., Hofius, D., Hofman, P., Höglinger, G. U., Höhfeld, J., Holz, M. K., Hong, Y., Hood, D. A., Hoozemans, J. J. M., Hoppe, T., Hsu, C., Hsu, C. Y., Hsu, L. C., Hu, D., Hu, G., Hu, H. M., Hu, H., Hu, M. C., Hu, Y. C., Hu, Z. W., Hua, F., Hua, Y., Huang, C., Huang, H. L., Huang, K. H., Huang, K. Y., Huang, S., Huang, S., Huang, W. P., Huang, Y. R., Huang, Y., Huang, Y., Huber, T. B., Huebbe, P., Huh, W. K., Hulmi, J. J., Hur, G. M., Hurley, J. H., Husak, Z., Hussain, S. N. A., Hussain, S., Hwang, J. J., Hwang, S., Hwang, T. I. S., Ichihara, A., Imai, Y., Imbriano, C., Inomata, M., Into, T., Iovane, V., Iovanna, J. L., Iozzo, R. V., Ip, N. Y., Irazoqui, J. E., Iribarren, P., Isaka, Y., Isakovic, A. J., Ischiropoulos, H., Isenberg, J. S., Ishaq, M., Ishida, H., Ishii, I., Ishmael, J. E., Isidoro, C., Isobe, K. I., Isono, E., Issazadeh-Navikas, S., Itahana, K., Itakura, E., Ivanov, A. I., Iyer, A. K. V., Izquierdo, J. M., Izumi, Y., Izzo, V., Jäättelä, M., Jaber, N., Jackson, D. J., Jackson, W. T., Jacob, T. G., Jacques, T. S., Jagannath, C., Jain, A., Jana, N. R., Jang, B. K., Jani, A., Janji, B., Jannig, P. R., Jansson, P. J., Jean, S., Jendrach, M., Jeon, J. H., Jessen, N., Jeung, E. B., Jia, K., Jia, L., Jiang, H., Jiang, H., Jiang, L., Jiang, T., Jiang, X., Jiang, X., Jiang, Y., Jiang, Y., Jiménez, A., Jin, C., Jin, H., Jin, L., Jin, M., Jin, S., Jinwal, U. K., Jo, E. K., Johansen, T., Johnson, D. E., Johnson, G. V. W., Johnson, J. D., Jonasch, E., Jones, C., Joosten, L. A. B., Jordan, J., Joseph, A. M., Joseph, B., Joubert, A. M., Ju, D., Ju, J., Juan, H. F., Juenemann, K., Juhász, G., Jung, H. S., Jung, J. U., Jung, Y. K., Jungbluth, H., Justice, M. J., Jutten, B., Kaakoush, N. O., Kaarniranta, K., Kaasik, A., Kabuta, T., Kaeffer, B., Kågedal, K., Kahana, A., Kajimura, S., Kakhlon, O., Kalia, M., Kalvakolanu, D. V., Kamada, Y., Kambas, K., Kaminskyy, V. O., Kampinga, H. 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D., Zhang, F., Zhang, G., Zhang, G. C., Zhang, H., Zhang, H., Zhang, H., Zhang, J., Zhang, J., Zhang, J., Zhang, J. P., Zhang, L., Zhang, L., Zhang, L., Zhang, M. Y., Zhang, X., Zhang, X. D., Zhang, Y., Zhang, Y., Zhang, Y., Zhang, Y., Zhang, Y., Zhao, M., Zhao, W. L., Zhao, X., Zhao, Y. G., Zhao, Y., Zhao, Y., Zhao, Y. X., Zhao, Z., Zhao, Z. J., Zheng, D., Zheng, X. L., Zheng, X., Zhivotovsky, B., Zhong, Q., Zhou, G. Z., Zhou, G., Zhou, H., Zhou, S. F., Zhou, X. J., Zhu, H., Zhu, H., Zhu, W. G., Zhu, W., Zhu, X. F., Zhu, Y., Zhuang, S. M., Zhuang, X., Ziparo, E., Zois, C. E., Zoladek, T., Zong, W. X., Zorzano, A. & Zughaier, S. M., Jan 21 2016, In: Autophagy. 12, 1, p. 1-222 222 p.

    Research output: Contribution to journalReview articlepeer-review

  • MicroRNA-34a and Impaired FGF19/21 Signaling in Obesity

    Fu, T. & Kemper, J. K., 2016, Klotho, 2016. Litwack, G. (ed.). Academic Press Inc., p. 175-196 22 p. (Vitamins and Hormones; vol. 101).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  • 2015

    A dysregulated acetyl/SUMO switch of FXR promotes hepatic inflammation in obesity

    Kim, D. H., Xiao, Z., Kwon, S., Sun, X., Ryerson, D., Tkac, D., Ma, P., Wu, S. Y., Chiang, C. M., Zhou, E., Xu, H. E., Palvimo, J. J., Chen, L. F., Kemper, B. & Kemper, J. K., Jan 14 2015, In: EMBO Journal. 34, 2, p. 184-199 16 p.

    Research output: Contribution to journalArticlepeer-review

  • Farnesoid X Receptor-Induced Lysine-Specific Histone Demethylase Reduces Hepatic Bile Acid Levels and Protects the Liver Against Bile Acid Toxicity

    Kim, Y. C., Fang, S., Byun, S., Seok, S., Kemper, B. & Kemper, J. K., Jul 1 2015, In: Hepatology. 62, 1, p. 220-231 12 p.

    Research output: Contribution to journalArticlepeer-review

  • Liver ChIP-seq analysis in FGF19-treated mice reveals SHP as a global transcriptional partner of SREBP-2

    Kim, Y. C., Byun, S., Zhang, Y., Seok, S., Kemper, B., Ma, J. & Kemper, J. K., Dec 4 2015, In: Genome biology. 16, 1, 268.

    Research output: Contribution to journalArticlepeer-review

  • 2014

    MicroRNA 34a inhibits beige and brown fat formation in obesity in part by suppressing adipocyte fibroblast growth factor 21 signaling and SIRT1 function

    Fu, T., Seok, S., Choi, S., Huang, Z., Suino-Powell, K., Eric Xu, H., Kemper, B. & Kemper, J. K., 2014, In: Molecular and cellular biology. 34, 22, p. 4130-4142 13 p.

    Research output: Contribution to journalArticlepeer-review

  • Transcriptional regulation of autophagy by an FXR-CREB axis

    Seok, S., Fu, T., Choi, S. E., Li, Y., Zhu, R., Kumar, S., Sun, X., Yoon, G., Kang, Y., Zhong, W., Ma, J., Kemper, B. & Kemper, J. K., Dec 4 2014, In: Nature. 516, 729, p. 108-111 4 p.

    Research output: Contribution to journalArticlepeer-review

  • 2013

    Bile acid signal-induced phosphorylation of small heterodimer partner by protein kinase Cζ is critical for epigenomic regulation of liver metabolic genes

    Seok, S., Kanamaluru, D., Xiao, Z., Ryerson, D., Choi, S. E., Suino-Powell, K., Xu, H. E., Veenstra, T. D. & Kemper, J. K., Aug 9 2013, In: Journal of Biological Chemistry. 288, 32, p. 23252-23263 12 p.

    Research output: Contribution to journalArticlepeer-review

  • Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT

    Choi, S. E., Fu, T., Seok, S., Kim, D. H., Yu, E., Lee, K. W., Kang, Y., Li, X., Kemper, B. & Kemper, J. K., Dec 2013, In: Aging Cell. 12, 6, p. 1062-1072 11 p.

    Research output: Contribution to journalArticlepeer-review

  • Epigenomic regulation of bile acid metabolism: Emerging role of transcriptional cofactors

    Smith, Z., Ryerson, D. & Kemper, J. K., Apr 10 2013, In: Molecular and Cellular Endocrinology. 368, 1-2, p. 59-70 12 p.

    Research output: Contribution to journalReview articlepeer-review

  • Regulation of SIRT1 by microRNAs

    Choi, S. E. & Kemper, J. K., Nov 2013, In: Molecules and Cells. 36, 5, p. 385-392 8 p.

    Research output: Contribution to journalShort surveypeer-review

  • Sirtuin 1 Deacetylase. A Key Regulator of Hepatic Lipid Metabolism.

    Kemper, J. K., Choi, S. E. & Kim, D. H., 2013, Vitamins and Hormones. Academic Press Inc., p. 385-404 20 p. (Vitamins and Hormones; vol. 91).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  • 2012

    Aberrantly elevated microRNA-34a in obesity attenuates hepatic responses to FGF19 by targeting a membrane coreceptor β-Klotho

    Fu, T., Choi, S. E., Kim, D. H., Seok, S., Suino-Powell, K. M., Xu, H. E. & Kemper, J. K., Oct 2 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 40, p. 16137-16142 6 p.

    Research output: Contribution to journalArticlepeer-review

  • Cross-regulation of protein stability by p53 and nuclear receptor SHP

    Yang, Z., Zhang, Y., Kemper, J. K. & Wang, L., Jun 21 2012, In: PloS one. 7, 6, e39789.

    Research output: Contribution to journalArticlepeer-review

  • Genomic analysis of hepatic farnesoid X receptor binding sites reveals altered binding in obesity and direct gene repression by farnesoid X receptor in mice

    Lee, J., Seok, S., Yu, P., Kim, K., Smith, Z., Rivas-Astroza, M., Zhong, S. & Kemper, J. K., Jul 2012, In: Hepatology. 56, 1, p. 108-117 10 p.

    Research output: Contribution to journalArticlepeer-review

  • Hepatic deletion of SIRT1 decreases hepatocyte nuclear factor 1α/farnesoid X receptor signaling and induces formation of cholesterol gallstones in mice

    Purushotham, A., Xu, Q., Lu, J., Foley, J. F., Yan, X., Kim, D. H., Kemper, J. K. & Li, X., Apr 2012, In: Molecular and cellular biology. 32, 7, p. 1226-1236 11 p.

    Research output: Contribution to journalArticlepeer-review

  • 2011

    Arginine methylation by PRMT5 at a naturally occurring mutation site Is critical for liver metabolic regulation by small heterodimer partner

    Kanamaluru, D., Xiao, Z., Fang, S., Choi, S. E., Kim, D. H., Veenstra, T. D. & Kemper, J. K., Apr 2011, In: Molecular and cellular biology. 31, 7, p. 1540-1550 11 p.

    Research output: Contribution to journalArticlepeer-review

  • Ligand-dependent regulation of the activity of the orphan nuclear receptor, small heterodimer partner (SHP), in the repression of bile acid biosynthetic CYP7A1 and CYP8B1 genes

    Miao, J., Choi, S. E., Seok, S. M., Yang, L., Zuercher, W. J., Xu, Y., Willson, T. M., Eric Xu, H. & Kemper, J. K., Jul 1 2011, In: Molecular Endocrinology. 25, 7, p. 1159-1169 11 p.

    Research output: Contribution to journalArticlepeer-review

  • 2010

    A pathway involving farnesoid X receptor and small heterodimer partner positively regulates hepatic sirtuin 1 levels via MicroRNA-34a inhibition

    Lee, J., Padhye, A., Sharma, A., Song, G., Miao, J., Mo, Y. Y., Wang, L. & Kemper, J. K., Apr 23 2010, In: Journal of Biological Chemistry. 285, 17, p. 12604-12611 8 p.

    Research output: Contribution to journalArticlepeer-review

  • Controlling SIRT1 expression by microRNAs in health and metabolic disease

    Lee, J. & Kemper, J. K., Aug 2010, In: Aging. 2, 8, p. 527-534 8 p.

    Research output: Contribution to journalArticlepeer-review

  • SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism

    Ponugoti, B., Kim, D. H., Xiao, Z., Smith, Z., Miao, J., Zang, M., Wu, S. Y., Chiang, C. M., Veenstra, T. D. & Kemper, J. K., Oct 29 2010, In: Journal of Biological Chemistry. 285, 44, p. 33959-33970 12 p.

    Research output: Contribution to journalArticlepeer-review

  • 2009

    Bile acid signaling pathways increase stability of small heterodimer partner (SHP) by inhibiting ubiquitin-proteasomal degradation

    Miao, J., Xiao, Z., Kanamaluru, D., Min, G., Yau, P. M., Veenstra, T. D., Ellis, E., Strom, S., Suino-Powell, K., Xu, H. E. & Kemper, J. K., Apr 15 2009, In: Genes and Development. 23, 8, p. 986-996 11 p.

    Research output: Contribution to journalArticlepeer-review

  • Functional specificities of Brm and Brg-1 Swi/Snf ATPases in the feedback regulation of hepatic bile acid biosynthesis

    Miao, J., Fang, S., Lee, J., Comstock, C., Knudsen, K. E. & Kemper, J. K., Dec 2009, In: Molecular and cellular biology. 29, 23, p. 6170-6181 12 p.

    Research output: Contribution to journalArticlepeer-review

  • FXR Acetylation Is Normally Dynamically Regulated by p300 and SIRT1 but Constitutively Elevated in Metabolic Disease States

    Kemper, J. K., Xiao, Z., Ponugoti, B., Miao, J., Fang, S., Kanamaluru, D., Tsang, S., Wu, S. Y., Chiang, C. M. & Veenstra, T. D., Nov 4 2009, In: Cell Metabolism. 10, 5, p. 392-404 13 p.

    Research output: Contribution to journalArticlepeer-review

  • 2008

    The p300 acetylase is critical for ligand-activated farnesoid X receptor (FXR) induction of SHP

    Fang, S., Tsang, S., Jones, R., Ponugoti, B., Yoon, H., Wu, S. Y., Chiang, C. M., Willson, T. M. & Kemper, J. K., Dec 12 2008, In: Journal of Biological Chemistry. 283, 50, p. 35086-35095 10 p.

    Research output: Contribution to journalArticlepeer-review

  • 2007

    Coordinated recruitment of histone methyltransferase G9a and other chromatin-modifying enzymes in SHP-mediated regulation of hepatic bile acid metabolism

    Fang, S., Miao, J., Xiang, L., Ponugoti, B., Treuter, E. & Kemper, J. K., Feb 2007, In: Molecular and cellular biology. 27, 4, p. 1407-1424 18 p.

    Research output: Contribution to journalArticlepeer-review

  • 2006

    Analysis of multiple nuclear receptor binding sites for CAR/RXR in the phenobarbital responsive unit of CYP2B2

    Zhang, Q., Bae, Y., Kemper, J. K. & Kemper, B., Jul 15 2006, In: Archives of Biochemistry and Biophysics. 451, 2, p. 119-127 9 p.

    Research output: Contribution to journalArticlepeer-review

  • Brd4 links chromatin targeting to HPV transcriptional silencing

    Wu, S. Y., Lee, A. Y., Hou, S. Y., Kemper, J. K., Erdjument-Bromage, H., Tempst, P. & Chiang, C. M., Sep 1 2006, In: Genes and Development. 20, 17, p. 2383-2396 14 p.

    Research output: Contribution to journalArticlepeer-review

  • 2004

    Differential regulation of the human progesterone receptor gene through an estrogen response element half site and Sp1 sites

    Petz, L. N., Ziegler, Y. S., Schultz, J. R., Kim, H., Kemper, J. K. & Nardulli, A. M., Feb 2004, In: Journal of Steroid Biochemistry and Molecular Biology. 88, 2, p. 113-122 10 p.

    Research output: Contribution to journalArticlepeer-review

  • Ligand-activated pregnane X receptor interferes with HNF-4 signaling by targeting a common coactivator PGC-1α. Functional implications in hepatic cholesterol and glucose metabolism

    Bhalla, S., Ozalp, C., Fang, S., Xiang, L. & Kemper, J. K., Oct 22 2004, In: Journal of Biological Chemistry. 279, 43, p. 45139-45147 9 p.

    Research output: Contribution to journalArticlepeer-review

  • Repression of CAR-Mediated Transactivation of CYP2B Genes by the Orphan Nuclear Receptor, Short Heterodimer Partner (SHP)

    Bae, Y., Kemper, J. K. & Kemper, B., Feb 2004, In: DNA and Cell Biology. 23, 2, p. 81-91 11 p.

    Research output: Contribution to journalArticlepeer-review