John Alan Gerlt

1973 …2019
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Phosphopyruvate Hydratase Medicine & Life Sciences
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mandelate racemase Medicine & Life Sciences
Catalytic Domain Medicine & Life Sciences
Carboxy-Lyases Chemical Compounds
Protons Medicine & Life Sciences
Racemases and Epimerases Medicine & Life Sciences
Escherichia coli Chemical Compounds

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Research Output 1973 2019

Discovery of novel bacterial queuine salvage enzymes and pathways in human pathogens

Yuan, Y., Zallot, R., Grove, T. L., Payan, D. J., Martin-Verstraete, I., Šepić, S., Balamkundu, S., Neelakandan, R., Gadi, V. K., Liu, C. F., Swairjo, M. A., Dedon, P. C., Almo, S. C., Gerlt, J. A. & de Crécy-Lagard, V., Sep 17 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 38, p. 19126-19135 10 p.

Research output: Contribution to journalArticle

Open Access
Bacteria
queuine tRNA-ribosyltransferase
Enzymes
Eukaryota
Nucleoside Q

Novel metabolic pathways and regulons for hexuronate utilization in Proteobacteria

Bouvier, J. T., Sernova, N. V., Ghasempur, S., Rodionova, I. A., Vetting, M. W., Al-Obaidi, N. F., Almo, S. C., Gerlt, J. A. & Rodionov, D. A., Jan 1 2019, In : Journal of bacteriology. 201, 2, e00431-18.

Research output: Contribution to journalArticle

Regulon
Proteobacteria
Metabolic Networks and Pathways
Ralstonia pickettii
Enzymes

The EFI Web Resource for Genomic Enzymology Tools: Leveraging Protein, Genome, and Metagenome Databases to Discover Novel Enzymes and Metabolic Pathways

Zallot, R., Oberg, N. & Gerlt, J. A., Oct 15 2019, In : Biochemistry. 58, 41, p. 4169-4182 14 p.

Research output: Contribution to journalArticle

Open Access
Metagenome
Metabolic Networks and Pathways
Genes
Genome
Databases

Editorial overview: Novel enzymes, coenzymes, and metabolic pathways

Gerlt, J. A. & Erb, T. J., Dec 2018, In : Current Opinion in Chemical Biology. 47, p. A4-A6

Research output: Contribution to journalEditorial

Enzymes and Coenzymes
Metabolic Networks and Pathways

Enzyme Architecture: Breaking Down the Catalytic Cage that Activates Orotidine 5′-Monophosphate Decarboxylase for Catalysis

Reyes, A. C., Plache, D. C., Koudelka, A. P., Amyes, T. L., Gerlt, J. A. & Richard, J. P., Dec 19 2018, In : Journal of the American Chemical Society. 140, 50, p. 17580-17590 11 p.

Research output: Contribution to journalArticle

Carboxy-Lyases
catalysis
Catalysis
Yeast
Enzymes