James McClurg Slauch

1985 …2019
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Research Output 1985 2019

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Acetylation (O-factor 5) affects the structural and immunological properties of Salmonella typhimurium lipopolysaccharide O antigen

Slauch, J. M., Mahan, M. J., Michetti, P., Neutra, M. R. & Mekalanos, J. J., Jan 1 1995, In : Infection and immunity. 63, 2, p. 437-441 5 p.

Research output: Contribution to journalArticle

O Antigens
Salmonella typhimurium
Acetylation
Lipopolysaccharides
Epitopes

Antibiotic-based selection for bacterial genes that are specifically induced during infection of a host

Mahan, M. J., Tobias, J. W., Slauch, J. M., Hanna, P. C., Collier, R. J. & Mekalanos, J. J., Jan 31 1995, In : Proceedings of the National Academy of Sciences of the United States of America. 92, 3, p. 669-673 5 p.

Research output: Contribution to journalArticle

Bacterial Genes
Anti-Bacterial Agents
Chloramphenicol O-Acetyltransferase
Infection
Genes

Antigen-specific bacterial vaccine combined with anti-PD-L1 rescues dysfunctional endogenous T cells to reject long-established cancer

Binder, D. C., Engels, B., Arina, A., Yu, P., Slauch, J. M., Fu, Y. X., Karrison, T., Burnette, B., Idel, C., Zhao, M., Hoffman, R. M., Munn, D. H., Rowley, D. A. & Schreiber, H., Aug 1 2013, In : Cancer Immunology Research. 1, 2, p. 123-133 11 p.

Research output: Contribution to journalArticle

Bacterial Vaccines
T-Lymphocytes
Antigens
Neoplasms
Blocking Antibodies

Characterization of grvA, an antivirulence gene on the Gifsy-2 phage in Salmonella enterica serovar Typhimurium

Ho, T. D. & Slauch, J. M., Jan 23 2001, In : Journal of bacteriology. 183, 2, p. 611-620 10 p.

Research output: Contribution to journalArticle

Salmonella enterica
Bacteriophages
Virulence
Virulence Factors
Phenotype

cis-Acting ompF mutations that result in OmpR-dependent constitutive expression

Slauch, J. M. & Silhavy, T. J., Jan 1 1991, In : Journal of bacteriology. 173, 13, p. 4039-4048 10 p.

Research output: Contribution to journalArticle

Genetic Promoter Regions
Osmolar Concentration
Porins
Mutation
Sepharose

Construction of targeted single copy lac fusions using λ Red and FLP-mediated site-specific recombination in bacteria

Ellermeier, C. D., Janakiraman, A. & Slauch, J. M., May 15 2002, In : Gene. 290, 1-2, p. 153-161 9 p.

Research output: Contribution to journalArticle

Genetic Recombination
Bacteria
Plasmids
Galactosidases
Replication Origin

Controlled activity of the Salmonella invasion-associated injectisome reveals its intracellular role in the cytosolic population

Klein, J. A., Grenz, J. R., Slauch, J. M. & Knodler, L. A., Nov 1 2017, In : mBio. 8, 6, e01931-17.

Research output: Contribution to journalArticle

Salmonella
Epithelial Cells
Population
Vacuoles
Salmonella enterica
Genomic Islands
Salmonella
Gene Regulatory Networks
Gene Expression
Type I Secretion Systems
Salmonella
Copper
Infection
Superoxides
Superoxide Dismutase

Differences in enzymatic properties allow SodCI but not SodCII to contribute to virulence in Salmonella enterica serovar typhimurium strain 14028

Krishnakumar, R., Craig, M., Imlay, J. A. & Slauch, J. M., Aug 1 2004, In : Journal of bacteriology. 186, 16, p. 5230-5238 9 p.

Research output: Contribution to journalArticle

Salmonella enterica
Virulence
Copper
Phenotype
Enzymes

Differences in regulatory sequences of naturally occurring JC virus variants

Martin, J. D., King, D. M., Slauch, J. M. & Frisque, R. J., Jan 1 1985, In : Journal of virology. 53, 1, p. 306-311 6 p.

Research output: Contribution to journalArticle

JC polyomavirus
JC Virus
regulatory sequences
DNA
Nucleic Acid Regulatory Sequences

DsbL and DsbI contribute to periplasmic disulfide bond formation in Salmonella enterica serovar Typhimurium

Lin, D., Kim, B. & Slauch, J. M., Dec 11 2009, In : Microbiology. 155, 12, p. 4014-4024 11 p.

Research output: Contribution to journalArticle

arylsulfate sulfotransferase
Salmonella enterica
Disulfides
Periplasmic Proteins
Genomic Islands
O Antigens
Salmonella typhimurium
Acetylation
Antibody Formation
Lipopolysaccharides
Salmonella enterica
Superoxides
Peptide Hydrolases
Periplasm
Osmotic Pressure

Environment-Friendly Antibiofouling Superhydrophobic Coatings

Razavi, S. M. R., Oh, J., Haasch, R. T., Kim, K., Masoomi, M., Bagheri, R., Slauch, J. M. & Miljkovic, N., Sep 3 2019, In : ACS Sustainable Chemistry and Engineering. 7, 17, p. 14509-14520 12 p.

Research output: Contribution to journalArticle

coating
Coatings
Contact angle
Underwater structures
Water filtration

EnvZ functions through OmpR to control porin gene expression in Escherichia coli K-12

Slauch, J. M., Garrett, S., Jackson, D. E. & Silhavy, T. J., Jan 1 1988, In : Journal of bacteriology. 170, 1, p. 439-441 3 p.

Research output: Contribution to journalArticle

Porins
Escherichia coli
Gene Expression
Membrane Proteins
Proteins

FliZ regulates expression of the Salmonella pathogenicity island 1 invasion locus by controlling HilD protein activity in Salmonella enterica serovar typhimurium

Cott Chubiz, J. E., Golubeva, Y. A., Lin, D., Miller, L. D. & Slauch, J. M., Dec 1 2010, In : Journal of bacteriology. 192, 23, p. 6261-6270 10 p.

Research output: Contribution to journalArticle

Genomic Islands
Salmonella enterica
Salmonella
Proteins
Protease La

Fur regulates expression of the Salmonella pathogenicity island 1 type III secretion system through HilD

Ellermeier, J. R. & Slauch, J. M., Jan 1 2008, In : Journal of bacteriology. 190, 2, p. 476-486 11 p.

Research output: Contribution to journalArticle

Genomic Islands
Salmonella
Salmonella enterica
Type III Secretion Systems
Iron

Genetic analysis of the switch that controls porin gene expression in Escherichia coli K-12

Slauch, J. M. & Silhavy, T. J., Nov 20 1989, In : Journal of Molecular Biology. 210, 2, p. 281-292 12 p.

Research output: Contribution to journalArticle

Porins
Osmolar Concentration
Escherichia coli
Gene Expression
DNA-Binding Proteins

Genetic fusions as experimental tools

Slauch, J. M. & Silhavy, T. J., Jan 1 1991, In : Methods in enzymology. 204, C, p. 213-248 36 p.

Research output: Contribution to journalArticle

DNA Transposable Elements
Fusion reactions

Heterogeneity of vaginal microbial communities within individuals

Kim, T. K., Thomas, S. M., Ho, M., Sharma, S., Reich, C. I., Frank, J. A., Yeater, K. M., Biggs, D. R., Nakamura, N., Stumpf, R., Leigh, S. R., Tapping, R. I., Blanke, S. R., Slauch, J. M., Gaskins, H. R., Weisbaum, J. S., Olsen, G. J., Hoyer, L. L. & Wilson, B. A., Apr 1 2009, In : Journal of Clinical Microbiology. 47, 4, p. 1181-1189 9 p.

Research output: Contribution to journalArticle

Microbiota
Ecosystem
Gene Library
rRNA Genes
Cervix Uteri
Genomic Islands
Salmonella enterica
Salmonella
Genes
Serogroup

HilE regulates HilD by blocking DNA binding in Salmonella enterica serovar Typhimurium

Grenz, J. R., Chubiz, J. E. C., Thaprawat, P. & Slauch, J. M., Apr 1 2018, In : Journal of bacteriology. 200, 8, e00750-17.

Research output: Contribution to journalArticle

Salmonella enterica
Genomic Islands
Salmonella
DNA
Proteins

How does the oxidative burst of macrophages kill bacteria? Still an open question

Slauch, J. M., May 1 2011, In : Molecular Microbiology. 80, 3, p. 580-583 4 p.

Research output: Contribution to journalArticle

Respiratory Burst
Salmonella
Reactive Oxygen Species
Phagosomes
Macrophages

Identification of GtgE, a novel virulence factor encoded on the Gifsy-2 bacteriophage of Salmonella enterica serovar typhimurium

Ho, T. D., Figueroa-Bossi, N., Wang, M., Uzzau, S., Bossi, L. & Slauch, J. M., Oct 1 2002, In : Journal of bacteriology. 184, 19, p. 5234-5239 6 p.

Research output: Contribution to journalArticle

Salmonella enterica
Virulence Factors
Bacteriophages
Virulence
Genes

Immunomagnetic separation combined with RT-qPCR for determining the efficacy of disinfectants against human noroviruses

Liu, P., Kim, M., Schlesinger, D., Kranz, C., Ha, S., Ha, J., Slauch, J., Baek, S. & Moe, C., Jan 1 2015, In : Journal of Infection and Public Health. 8, 2, p. 145-154 10 p.

Research output: Contribution to journalArticle

Immunomagnetic Separation
Norovirus
Disinfectants
Polymerase Chain Reaction
Norwalk virus

Integrating global regulatory input into the Salmonella pathogenicity Island 1 type III secretion system

Golubeva, Y. A., Sadik, A. Y., Ellermeier, J. R. & Slauch, J. M., Jan 1 2012, In : Genetics. 190, 1, p. 79-90 12 p.

Research output: Contribution to journalArticle

Genomic Islands
Salmonella
Type III Secretion Systems
Genes
Salmonella enterica

Intestinal long-chain fatty acids act as a direct signal to modulate expression of the Salmonella pathogenicity island 1 type III secretion system

Golubeva, Y. A., Ellermeier, J. R., Chubiz, J. E. C. & Slauch, J. M., Feb 16 2016, In : mBio. 7, 1, e02170-15.

Research output: Contribution to journalArticle

Genomic Islands
Salmonella
Fatty Acids
Cues
Epithelial Cells

In vivo expression technology for selection of bacterial genes specifically induced in host Tissues

Slauch, J. M., Mahan, M. J. & Mekalanos, J. J., Jan 1 1994, In : Methods in enzymology. 235, C, p. 481-492 12 p.

Research output: Contribution to journalArticle

Bacterial Genes
Genes
Tissue
Technology
Vaccines

IVET and RIVET: Use of gene fusions to identify bacterial virulence factors specifically induced in host tissues

Slauch, J. M. & Camilli, A., Jan 1 2000, In : Methods in enzymology. 326, p. 73-96 24 p.

Research output: Contribution to journalArticle

Gene Fusion
Virulence Factors
Fusion reactions
Genes
Tissue

Measurement of transcriptional activity in pathogenic bacteria recovered directly from infected host tissue

Slauch, J. M., Mahan, M. J. & Mekalanos, J. J., Jan 1 1994, In : BioTechniques. 16, 4, p. 641-642+644

Research output: Contribution to journalArticle

Bacteria
Genes
Tissue
Galactosidases
Lac Operon

Metal-independent variants of phosphoglycerate mutase promote resistance to nutritional immunity and retention of glycolysis during infection

Radin, J. N., Kelliher, J. L., Solórzano, P. K. P., Grim, K. P., Ramezanifard, R., Slauch, J. M. & Kehl-Fie, T. E., Jul 2019, In : PLoS pathogens. 15, 7, e1007971.

Research output: Contribution to journalArticle

Open Access
Phosphoglycerate Mutase
Glycolysis
Manganese
Immunity
Metals

Molecular characterization of the oafA locus responsible for acetylation of Salmonella typhimurium O-antigen: OafA is a member of a family of integral membrane trans-acylases

Slauch, J. M., Lee, A. A., Mahan, M. J. & Mekalanos, J. J., Jan 1 1996, In : Journal of bacteriology. 178, 20, p. 5904-5909 6 p.

Research output: Contribution to journalArticle

amidase
O Antigens
Salmonella typhimurium
Acetylation
Membranes

Monoclonal immunoglobulin a prevents adherence and invasion of polarized epithelial cell monolayers by Salmonella typhimurium

Michetti, P., Porta, N., Mahan, M. J., Slauch, J. M., Mekalanos, J. J., Blum, A. L., Kraehenbuhl, J. P. & Neutra, M. R., Oct 1994, In : Gastroenterology. 107, 4, p. 915-923 9 p.

Research output: Contribution to journalArticle

Salmonella typhimurium
Immunoglobulin A
Immunoglobulins
Epithelial Cells
Madin Darby Canine Kidney Cells

Monoclonal secretory immunoglobulin A protects mice against oral challenge with the invasive pathogen Salmonella typhimurium

Michetti, P., Mahan, M. J., Slauch, J. M., Mekalanos, J. J. & Neutra, M. R., Jan 1 1992, In : Infection and immunity. 60, 5, p. 1786-1792 7 p.

Research output: Contribution to journalArticle

Secretory Immunoglobulin A
Salmonella typhimurium
Immunoglobulin A
Hybridomas
Epitopes

Mutations that affect separate functions of OmpR the phosphorylated regulator of porin transcription in Escherichia coli

Russo, F. D., Slauch, J. M. & Silhavy, T. J., May 20 1993, In : Journal of Molecular Biology. 231, 2, p. 261-273 13 p.

Research output: Contribution to journalArticle

Porins
Escherichia coli
Mutation
Activation Analysis
Phosphorylation

OmpC is the receptor for gifsy-1 and gifsy-2 bacteriophages of salmonella

Ho, T. D. & Slauch, J. M., Feb 10 2001, In : Journal of bacteriology. 183, 4, p. 1495-1498 4 p.

Research output: Contribution to journalArticle

Salmonella Phages
Bacteriophages
Clone Cells
Salmonella enterica
Plasmids

Oxygen-dependent regulation of SPI1 type three secretion system by small RNAs in Salmonella enterica serovar Typhimurium

Kim, K., Golubeva, Y. A., Vanderpool, C. & Slauch, J. M., Mar 2019, In : Molecular Microbiology. 111, 3, p. 570-587 18 p.

Research output: Contribution to journalArticle

Genomic Islands
Salmonella enterica
Salmonella
RNA
Oxygen

Periplasmic superoxide dismutase SodCI of Salmonella binds peptidoglycan to remain tethered within the periplasm

Tidhar, A., Rushing, M. D., Kim, B. & Slauch, J. M., Sep 1 2015, In : Molecular Microbiology. 97, 5, p. 832-843 12 p.

Research output: Contribution to journalArticle

Periplasm
Peptidoglycan
Salmonella
Superoxide Dismutase
Superoxides

Phagocytic superoxide specifically damages an extracytoplasmic target to inhibit or kill Salmonella

Craig, M. & Slauch, J. M., Mar 23 2009, In : PloS one. 4, 3, e4975.

Research output: Contribution to journalArticle

Salmonella
Superoxides
superoxide anion
reactive oxygen species
Reactive Oxygen Species

Protecting against antimicrobial effectors in the phagosome allows SodCII to contribute to virulence in Salmonella enterica serovar Typhimurium

Kim, B., Richards, S. M., Gunn, J. S. & Slauch, J. M., Apr 1 2010, In : Journal of bacteriology. 192, 8, p. 2140-2149 10 p.

Research output: Contribution to journalArticle

Phagosomes
Salmonella enterica
Periplasm
Virulence
Peptide Hydrolases

Proteolytic inactivation of tissue factor pathway inhibitor by bacterial omptins

Yun, T. H., Cott, J. E., Tapping, R. I., Slauch, J. M. & Morrissey, J. H., Jan 29 2009, In : Blood. 113, 5, p. 1139-1148 10 p.

Research output: Contribution to journalArticle

Proteolysis
Plasminogen
Fibrin
Anticoagulants
Bacteria

Regulation of Salmonella enterica serovar Typhimurium mntH transcription by H2O2, Fe2+, and Mn2+

Kehres, D. G., Janakiraman, A., Slauch, J. M. & Maguire, M. E., Jun 8 2002, In : Journal of bacteriology. 184, 12, p. 3151-3158 8 p.

Research output: Contribution to journalArticle

Salmonella enterica
Escherichia coli
Binding Sites
Trans-Activators
DNA-Directed RNA Polymerases

Resolvase-in vivo expression technology analysis of the Salmonella enterica serovar typhimurium PhoP and PmrA regulons in BALB/c mice

Merighi, M., Ellermeier, C. D., Slauch, J. M. & Gunn, J. S., Nov 1 2005, In : Journal of bacteriology. 187, 21, p. 7407-7416 10 p.

Research output: Contribution to journalArticle

Regulon
Recombinases
Salmonella enterica
Lipopolysaccharides
Technology

Role of cross talk in regulating the dynamic expression of the flagellar Salmonella pathogenicity island 1 and type 1 fimbrial genes

Saini, S., Slauch, J. M., Aldridge, P. D. & Rao, C. V., Nov 2010, In : Journal of bacteriology. 192, 21, p. 5767-5777 11 p.

Research output: Contribution to journalArticle

Genomic Islands
Salmonella
Gene Expression
Genes
Salmonella enterica

RtsA and RtsB coordinately regulate expression of the invasion and flagellar genes in Salmonella enterica serovar typhimurium

Ellermeier, C. D. & Slauch, J. M., Sep 1 2003, In : Journal of bacteriology. 185, 17, p. 5096-5108 13 p.

Research output: Contribution to journalArticle

Genomic Islands
Salmonella enterica
Salmonella
Regulon
Operon

RtsA Coordinately Regulates DsbA and the Salmonella Pathogenicity Island 1 Type III Secretion System

Ellermeier, C. D. & Slauch, J. M., Jan 1 2004, In : Journal of bacteriology. 186, 1, p. 68-79 12 p.

Research output: Contribution to journalArticle

Genomic Islands
Salmonella
Cytosol
Infection
Protein Disulfide-Isomerases
Regulon
Salmonella enterica
Superoxide Dismutase
Macrophages
Superoxides

SdiA, an N-acylhomoserine lactone receptor, becomes active during the transit of Salmonella enterica through the gastrointestinal tract of turtles

Smith, J. N., Dyszel, J. L., Soares, J. A., Ellermeier, C. D., Altier, C., Lawhon, S. D., Adams, L. G., Konjufca, V., Curtiss, R., Slauch, J. M. & Ahmer, B. M. M., Jul 30 2008, In : PloS one. 3, 7, e2826.

Research output: Contribution to journalArticle

Salmonella
Turtles
Salmonella enterica
Lactones
lactones

Selection for bacterial genes that are specifically induced in host tissues: The hunt for virulence factors

Mahan, M. J., Slauch, J. M., Hanna, P. C., Camilli, A., Tobias, J. W., Waldor, M. K. & Mekalanos, J. J., 1993, In : Infectious Agents and Disease. 2, 4, p. 263-268 6 p.

Research output: Contribution to journalArticle

Bacterial Genes
Virulence Factors
Genes
Vaccines
Virulence