Research output per year
Research output per year
- 49 results
Search results
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2024
Finasteride delays atherosclerosis progression in mice and is associated with a reduction in plasma cholesterol in men
McQueen, P., Molina, D., Pinos, I., Krug, S., Taylor, A. J., LaFrano, M. R., Kane, M. A. & Amengual, J., Mar 2024, In: Journal of Lipid Research. 65, 3, 100507.Research output: Contribution to journal › Article › peer-review
Open Access -
FITM2 deficiency results in ER lipid accumulation, ER stress, and reduced apolipoprotein B lipidation and VLDL triglyceride secretion in vitro and in mouse liver
Wang, H., Nikain, C., Fortounas, K. I., Amengual, J., Tufanli, O., La Forest, M., Yu, Y., Wang, M. C., Watts, R., Lehner, R., Qiu, Y., Cai, M., Kurland, I. J., Goldberg, I. J., Rajan, S., Hussain, M. M., Brodsky, J. L. & Fisher, E. A., Dec 2024, In: Molecular Metabolism. 90, 102048.Research output: Contribution to journal › Article › peer-review
Open Access -
Immunometabolic effects of β -carotene and vitamin A in atherogenesis
Blanco, A. & Amengual, J., Nov 28 2024, In: Immunometabolism (United States). 6, 4, p. e00051Research output: Contribution to journal › Review article › peer-review
Open Access -
Maternal genetics and diet modulate vitamin A homeostasis of the offspring and affect the susceptibility to obesity in adulthood in mice
Srinivasagan, R., Galmes, S., Vasileva, D., Rubí, P., Palou, A., Amengual, J., Ribot, J., von Lintig, J. & Bonet, M. L., Sep 2024, In: American Journal of Physiology - Endocrinology and Metabolism. 327, 3, p. E258-E270Research output: Contribution to journal › Article › peer-review
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The low-density lipoprotein receptor contributes to carotenoid homeostasis by regulating tissue uptake and fecal elimination
Miller, A. P., Monroy, W. C., Soria, G. & Amengual, J., Oct 2024, In: Molecular Metabolism. 88, 102007.Research output: Contribution to journal › Article › peer-review
Open Access -
β-Carotene accelerates the resolution of atherosclerosis in mice
Pinos, I., Coronel, J., Albakri, A., Blanco, A., McQueen, P., Molina, D., Sim, J. Y., Fisher, E. A. & Amengual, J., Feb 6 2024, In: eLife. 12Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Bioavailability and provitamin A activity of neurosporaxanthin in mice
Miller, A. P., Hornero-Méndez, D., Bandara, S., Parra-Rivero, O., Limón, M. C., von Lintig, J., Avalos, J. & Amengual, J., Dec 2023, In: Communications biology. 6, 1, 1068.Research output: Contribution to journal › Article › peer-review
Open Access -
DIAPH1 mediates progression of atherosclerosis and regulates hepatic lipid metabolism in mice
Senatus, L., Egaña-Gorroño, L., López-Díez, R., Bergaya, S., Aranda, J. F., Amengual, J., Arivazhagan, L., Manigrasso, M. B., Yepuri, G., Nimma, R., Mangar, K. N., Bernadin, R., Zhou, B., Gugger, P. F., Li, H., Friedman, R. A., Theise, N. D., Shekhtman, A., Fisher, E. A. & Ramasamy, R. & 1 others, , Dec 2023, In: Communications biology. 6, 1, 280.Research output: Contribution to journal › Article › peer-review
Open Access -
Functional characterization of interleukin 4 and retinoic acid signaling crosstalk during alternative macrophage activation
Pinos, I., Yu, J., Pilli, N., Kane, M. A. & Amengual, J., Apr 2023, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1868, 4, 159291.Research output: Contribution to journal › Article › peer-review
Open Access -
Lycopene Accumulation in Transgenic Mice Lacking One or Both Carotenoid Cleaving Enzymes
Bradley, M. J., Black, M., Arballo, J. R., Amengual, J. & Erdman, J. W., Aug 2023, In: Journal of Nutrition. 153, 8, p. 2216-2227 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Acknowledgement to Reviewers of Immunometabolism in 2021
Leoncini, L., Acharya, M., Iritani, B. M., Cho, M. L., Chiarella, E., Elizabeth Floyd, Z., Heiker, J. T., Moreno-Navarrete, J. M., Bleakley, M., Tsukasaki, K., Mangalmurt, N. S., D’Alessandro, A., Kane, L. P., Morel, P. A., Bystrom, J., Othy, S., Kono, M., Berardi, E., De Santa, F. & Riksen, N. P. & 49 others, , Jan 1 2022, In: Immunometabolism (United States). 4, 1, e220005.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Development and validation of a method to deliver vitamin A to macrophages
Acharya, P., Black, M., Bressner, G. & Amengual, J., Jan 2022, Carotenoids: Biological Functions of Carotenoids and Apocarotenoids in Natural and Artificial Systems. Wurtzel, E. T. & Wurtzel, E. T. (eds.). Academic Press Inc., p. 363-389 27 p. (Methods in Enzymology; vol. 674).Research output: Chapter in Book/Report/Conference proceeding › Chapter
Open Access -
Fenretinide inhibits vitamin A formation from β-carotene and regulates carotenoid levels in mice
Miller, A. P., Black, M. & Amengual, J., Feb 2022, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1867, 2, 159070.Research output: Contribution to journal › Article › peer-review
Open Access -
The conversion of β-carotene to vitamin A in adipocytes drives the anti-obesogenic effects of β-carotene in mice
Coronel, J., Yu, J., Pilli, N., Kane, M. A. & Amengual, J., Dec 2022, In: Molecular Metabolism. 66, 101640.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Lycopene: A Critical Review of Digestion, Absorption, Metabolism, and Excretion
Arballo, J., Amengual Terrasa, J. & Erdman, J. W., Feb 25 2021, In: Antioxidants. 10, 3, p. 1-16 16 p., 342.Research output: Contribution to journal › Review article › peer-review
Open Access -
Short-term Acyl-CoA: Cholesterol acyltransferase inhibition, combined with apoprotein A1 overexpression, promotes atherosclerosis inflammation resolution in mice
Amengual, J., Ogando, Y., Nikain, C., Quezada, A., Qian, K., Vaisar, T. & Fisher, E. A., Mar 1 2021, In: Molecular Pharmacology. 99, 3, p. 175-183 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Neutrophil extracellular traps promote macrophage inflammation and impair atherosclerosis resolution in diabetic mice
Josefs, T., Barrett, T. J., Brown, E. J., Quezada, A., Wu, X., Voisin, M., Amengual, J. & Fisher, E. A., Mar 19 2020, In: JCI Insight. 5, 7, e134796.Research output: Contribution to journal › Article › peer-review
Open Access -
The role of β-carotene and vitamin A in atherogenesis: Evidences from preclinical and clinical studies
Miller, A. P., Coronel, J. & Amengual, J., Nov 2020, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1865, 11, 158635.Research output: Contribution to journal › Review article › peer-review
Open Access -
β-Carotene conversion to vitamin A delays atherosclerosis progression by decreasing hepatic lipid secretion in mice
Zhou, F., Wu, X., Pinos, I., Abraham, B. M., Barrett, T. J., von Lintig, J., Fisher, E. A. & Amengual, J., Nov 2020, In: Journal of Lipid Research. 61, 11, p. 1491-1503 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
β-Carotene oxygenase 1 activity modulates circulating cholesterol concentrations in mice and humans
Amengual, J., Coronel, J., Marques, C., Aradillas-García, C., Morales, J. M. V., Andrade, F. C. D., Erdman, J. W. & Teran-Garcia, M., Aug 1 2020, In: Journal of Nutrition. 150, 8, p. 2023-2030 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
Bioactive properties of carotenoids in human health
Amengual, J., Oct 2019, In: Nutrients. 11, 10, 2388.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Monocytes and macrophages in atherogenesis
Amengual, J. & Barrett, T. J., Oct 1 2019, In: Current Opinion in Lipidology. 30, 5, p. 401-408 8 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
β-carotene in obesity research: Technical considerations and current status of the field
Coronel, J., Pinos, I. & Amengual, J., Apr 2019, In: Nutrients. 11, 4, 842.Research output: Contribution to journal › Review article › peer-review
Open Access -
2018
Autophagy is required for sortilin-mediated degradation of apolipoprotein B100
Amengual, J., Guo, L., Strong, A., Madrigal-Matute, J., Wang, H., Kaushik, S., Brodsky, J. L., Rader, D. J., Cuervo, A. M. & Fisher, E. A., Feb 2018, In: Circulation Research. 122, 4, p. 568-582 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Retinoic Acid Increases Fatty Acid Oxidation and Irisin Expression in Skeletal Muscle Cells and Impacts Irisin in Vivo
Amengual, J., García-Carrizo, F. J., Arreguín, A., Mušinović, H., Granados, N., Palou, A., Bonet, M. L. & Ribot, J., Apr 1 2018, In: Cellular Physiology and Biochemistry. 46, 1, p. 187-202 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2017
Targeted Nanotherapeutics Encapsulating Liver X Receptor Agonist GW3965 Enhance Antiatherogenic Effects without Adverse Effects on Hepatic Lipid Metabolism in Ldlr−/− Mice
Yu, M., Amengual, J., Menon, A., Kamaly, N., Zhou, F., Xu, X., Saw, P. E., Lee, S. J., Si, K., Ortega, C. A., Choi, W. I., Lee, I. H., Bdour, Y., Shi, J., Mahmoudi, M., Jon, S., Fisher, E. A. & Farokhzad, O. C., Oct 25 2017, In: Advanced Healthcare Materials. 6, 20, 1700313.Research output: Contribution to journal › Article › peer-review
Open Access -
2016
Genetic dissection in a mouse model reveals interactions between carotenoids and lipid metabolism
Palczewski, G., Widjaja-Adhi, M. A. K., Amengual, J., Golczak, M. & Von Lintig, J., Sep 2016, In: Journal of Lipid Research. 57, 9, p. 1684-1695 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2015
Retinylamine benefits early diabetic retinopathy in mice
Liu, H., Tang, J., Du, Y., Lee, C. A., Golczak, M., Muthusamy, A., Antonetti, D. A., Veenstra, A. A., Amengual, J., Von Lintig, J., Palczewski, K. & Kern, T. S., Aug 28 2015, In: Journal of Biological Chemistry. 290, 35, p. 21568-21579 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2014
Evidence for compartmentalization of mammalian carotenoid metabolism
Palczewski, G., Amengual, J., Hoppel, C. L. & Von Lintig, J., Oct 1 2014, In: FASEB Journal. 28, 10, p. 4457-4469 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
STRA6 is critical for cellular vitamin A uptake and homeostasis
Amengual, J., Zhang, N., Kemerer, M., Maeda, T., Palczewski, K. & Von Lintig, J., Oct 15 2014, In: Human molecular genetics. 23, 20, p. 5402-5417 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
β-Carotene during the suckling period is absorbed intact and induces retinoic acid dependent responses similar to preformed vitamin A in intestine and liver, but not adipose tissue of young rats
Mušinović, H., Bonet, M. L., Granados, N., Amengual, J., von Lintig, J., Ribot, J. & Palou, A., Nov 1 2014, In: Molecular Nutrition and Food Research. 58, 11, p. 2157-2165 9 p.Research output: Contribution to journal › Article › peer-review
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2013
Diabetes-induced impairment in visual function in mice: Contributions of p38 MAPK, RAGE, leukocytes, and aldose reductase
Lee, C. A., Li, G., Patel, M. D., Mark Petrash, J., Benetz, B. A., Veenstra, A., Amengual, J., von Lintig, J., Burant, C. J., Tang, J. & Kern, T. S., Aug 6 2013, In: Investigative Ophthalmology and Visual Science. 55, 5, p. 2904-2910 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Genetics and diet regulate vitamin A production via the homeobox transcription factor ISX
Lobo, G. P., Amengual, J., Baus, D., Shivdasani, R. A., Taylor, D. & Von Lintig, J., Mar 29 2013, In: Journal of Biological Chemistry. 288, 13, p. 9017-9027 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Two carotenoid oxygenases contribute to Mammalian provitamin a metabolism
Amengual, J., Widjaja-Adhi, M. A. K., Rodriguez-Santiago, S., Hessel, S., Golczak, M., Palczewski, K. & Von Lintig, J., Nov 22 2013, In: Journal of Biological Chemistry. 288, 47, p. 34081-34096 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Vitamin A supplementation in early life affects later response to an obesogenic diet in rats
Granados, N., Amengual, J., Ribot, J., Musinovic, H., Ceresi, E., Von Lintig, J., Palou, A. & Bonet, M. L., Sep 2013, In: International Journal of Obesity. 37, 9, p. 1169-1176 8 p.Research output: Contribution to journal › Article › peer-review
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2012
Induction of carnitine palmitoyl transferase 1 and fatty acid oxidation by retinoic acid in HepG2 cells
Amengual, J., Petrov, P., Bonet, M. L., Ribot, J. & Palou, A., Nov 2012, In: International Journal of Biochemistry and Cell Biology. 44, 11, p. 2019-2027 9 p.Research output: Contribution to journal › Article › peer-review
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Lecithin: Retinol acyltransferase is critical for cellular uptake of vitamin A from serum retinol-binding protein
Amengual, J., Golczak, M., Palczewski, K. & Von Lintig, J., Jul 13 2012, In: Journal of Biological Chemistry. 287, 29, p. 24216-24227 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Mammalian Carotenoid-oxygenases: Key players for carotenoid function and homeostasis
Lobo, G. P., Amengual, J., Palczewski, G., Babino, D. & Von Lintig, J., Jan 2012, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1821, 1, p. 78-87 10 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
2011
A mitochondrial enzyme degrades Carotenoids and protects against oxidative stress
Amengual, J., Lobo, G. P., Golczak, M., Li, H. N. M., Klimova, T., Hoppel, C. L., Wyss, A., Palczewski, K. & Von Lintig, J., Mar 2011, In: FASEB Journal. 25, 3, p. 948-959 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Beta-carotene reduces body adiposity of mice via BCMO1
Amengual, J., Gouranton, E., van Helden, Y. G. J., Hessel, S., Ribot, J., Kramer, E., Kiec-Wilk, B., Razny, U., Lietz, G., Wyss, A., Dembinska-Kiec, A., Palou, A., Keijer, J., Landrier, J. F., Bonet, M. L. & von Lintig, J., 2011, In: PloS one. 6, 6, e20644.Research output: Contribution to journal › Article › peer-review
Open Access -
Dietary 9-cis-β,β-carotene fails to rescue vision in mouse models of leber congenital amaurosis
Maeda, T., Perusek, L., Amengual, J., Babino, D., Palczewski, K. & Von Lintig, J., Nov 2011, In: Molecular Pharmacology. 80, 5, p. 943-952 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Distinct effects of oleic acid and its trans-isomer elaidic acid on the expression of myokines and adipokines in cell models
Granados, N., Amengual, J., Ribot, J., Palou, A. & Luisa Bonet, M., Apr 28 2011, In: British Journal of Nutrition. 105, 8, p. 1226-1234 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2010
Downregulation of Fzd6 and Cthrc1 and upregulation of olfactory receptors and protocadherins by dietary beta-carotene in lungs of Bcmo1-/- mice
van Helden, Y. G. J., Godschalk, R. W., Heil, S. G., Bunschoten, A., Hessel, S., Amengual, J., Luisa Bonet, M., von Lintig, J., van Schooten, F. J. & Keijer, J., May 14 2010, In: Carcinogenesis. 31, 8, p. 1329-1337 9 p.Research output: Contribution to journal › Article › peer-review
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Knockout of the Bcmo1 gene results in an inflammatory response in female lung, which is suppressed by dietary beta-carotene
Van Helden, Y. G. J., Heil, S. G., Van Schooten, F. J., Kramer, E., Hessel, S., Amengual, J., Ribot, J., Teerds, K., Wyss, A., Lietz, G., Bonet, M. L., Von Lintig, J., Godschalk, R. W. L. & Keijer, J., Jun 2010, In: Cellular and Molecular Life Sciences. 67, 12, p. 2039-2056 18 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Retinoic acid treatment enhances lipid oxidation and inhibits lipid biosynthesis capacities in the liver of mice
Amengual, J., Ribot, J., Bonet, M. L. & Palou, A., 2010, In: Cellular Physiology and Biochemistry. 25, 6, p. 657-666 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
β,β-carotene decreases peroxisome proliferator receptor γ activity and reduces lipid storage capacity of adipocytes in a β,β-carotene oxygenase 1-dependent manner
Lobo, G. P., Amengual, J., Li, H. N. M., Golczak, M., Bonet, M. L., Palczewski, K. & Von Lintig, J., Sep 3 2010, In: Journal of Biological Chemistry. 285, 36, p. 27891-27899 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2009
β-Carotene conversion products and their effects on adipose tissue
Tourniaire, F., Gouranton, E., Von Lintig, J., Keijer, J., Bonet, M. L., Amengual, J., Lietz, G. & Landrier, J. F., Sep 2009, In: Genes and Nutrition. 4, 3, p. 179-187 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
2008
Retinoic acid treatment increases lipid oxidation capacity in skeletal muscle of mice
Amengual, J., Ribot, J., Bonet, M. L. & Palou, A., Mar 2008, In: Obesity. 16, 3, p. 585-591 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2007
CMO1 deficiency abolishes vitamin a production from β-carotene and alters lipid metabolism in mice
Hessel, S., Eichinger, A., Isken, A., Amengual, J., Hunzelmann, S., Hoeller, U., Elste, V., Hunziker, W., Goralczyk, R., Oberhauser, V., Von Lintig, J. & Wyss, A., Nov 16 2007, In: Journal of Biological Chemistry. 282, 46, p. 33553-33561 9 p.Research output: Contribution to journal › Article › peer-review
Open Access