1991 …2018
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Research Output 1991 2018

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Article
2018

Acne treatment: Analysis of acne-related social media posts and the impact on patient care

Urso, B., Updyke, K. M., Domozych, R., Solomon, J. A., Brooks, I. S., Burton, V. & Dellavalle, R. P., Jul 2018, In : Cutis. 102, 7, p. 41-43 3 p.

Research output: Contribution to journalArticle

Social Media
Acne Vulgaris
Patient Care
Therapeutics
Pharmacies
2017

Mobile Platform for Multiplexed Detection and Differentiation of Disease-Specific Nucleic Acid Sequences, Using Microfluidic Loop-Mediated Isothermal Amplification and Smartphone Detection

Chen, W., Yu, H., Sun, F., Ornob, A., Brisbin, R., Ganguli, A., Vemuri, V., Strzebonski, P., Cui, G., Allen, K. J., Desai, S. A., Lin, W., Nash, D. M., Hirschberg, D. L., Brooks, I., Bashir, R. & Cunningham, B. T., Nov 7 2017, In : Analytical chemistry. 89, 21, p. 11219-11226 8 p.

Research output: Contribution to journalArticle

Nucleic acid sequences
Smartphones
Pathogens
Microfluidics
Amplification
2015
Spinal Cord Injuries
Posture
Heart Rate
Healthy Volunteers
Electrocardiography
2008

Application of software design principles and debugging methods to an analgesia prescription reduces risk of severe injury from medical use of opioids

Belknap, S. M., Moore, H., Lanzotti, S. A., Yarnold, P. R., Getz, M., Deitrick, D. L., Peterson, A., Akeson, J., Maurer, T., Soltysik, R. C., Storm, G. A. & Brooks, I., Sep 1 2008, In : Clinical Pharmacology and Therapeutics. 84, 3, p. 385-392 8 p.

Research output: Contribution to journalArticle

Software Design
Analgesia
Opioid Analgesics
Prescriptions
Wounds and Injuries
2007

Breaking the silo. Using informatics to support clinical and translational science.

Valenta, A. L., Brooks, I., Laureto, R. A. & Ramaprasad, A., Sep 1 2007, In : Journal of healthcare information management : JHIM. 21, 4, p. 15-17 3 p.

Research output: Contribution to journalArticle

Medical Informatics
Informatics
Evidence-Based Medicine
Biomedical Research
2000

Measurement of protein interaction bioenergetics: Application to structural variants of anti-sCD4 antibody

Doyle, M. L., Brigham-Burke, M., Blackburn, M. N., Brooks, I. S., Smith, T. M., Newman, R., Reff, M., Stafford, W. F., Sweet, R. W., Truneh, A., Hensley, P. & O'Shannessy, D. J., Jan 1 2000, In : Methods in enzymology. 323, p. 207-230 24 p.

Research output: Contribution to journalArticle

Thermodynamics
Energy Metabolism
Anti-Idiotypic Antibodies
Kinetics
Antibodies
1996

Mutational effects on inclusion body formation in the periplasmic expression of the immunoglobulin VL domain REI

Chan, W., Helms, L. R., Brooks, I., Lee, G., Ngola, S., McNulty, D., Maleeff, B., Hensley, P. & Wetzel, R., Jan 1 1996, In : Folding and Design. 1, 2, p. 77-89 13 p.

Research output: Contribution to journalArticle

Inclusion Bodies
Immunoglobulins
Biophysics
Equilibrium constants
Amyloidosis
1995

Binding interactions of human interleukin 5 with its receptor α subunit. Large scale production, structural, and functional studies of Drosophila- expressed recombinant proteins

Chaiken, I., Johanson, K., Appelbaum, E., Doyle, M., Hensley, P., Zhao, B., Abdel- Meguid, S. S., Young, P., Cook, R., Carr, S., Maticon, R., Cusimano, D., Dul, E., Angelichio, M., Brooks, I., Winborne, E., McDonnell, P., Morton, T. & Bennett, D., Jan 1 1995, In : Journal of Biological Chemistry. 270, 16, p. 9459-9471 13 p.

Research output: Contribution to journalArticle

Interleukin-5
Recombinant Proteins
Drosophila
Interleukin-5 Receptors
Calorimetry

Biological and biophysical characterization of recombinant soluble human E-selectin purified at large scale by reversed-phase high-performance liquid chromatography

Burrows, S. D., Franklin, S. G., Brigham-Burke, M. R., Brooks, I. S., McNulty, D. E., Feild, J. A., Anumula, K. R. & O'Shannessy, D. J., Jun 23 1995, In : Journal of Chromatography B: Biomedical Sciences and Applications. 668, 2, p. 219-231 13 p.

Research output: Contribution to journalArticle

High performance liquid chromatography
Purification
Selectins
Carbohydrates
L-Selectin

Specific inhibition of herpes simplex virus DNA polymerase by helical peptides corresponding to the subunit interface

Digard, P., Williams, K. P., Hensley, P., Brooks, I. S., Dahl, C. E. & Coen, D. M., Feb 28 1995, In : Proceedings of the National Academy of Sciences of the United States of America. 92, 5, p. 1456-1460 5 p.

Research output: Contribution to journalArticle

Peptides
Catalytic Domain
Circular Dichroism
Ultracentrifugation
DNA-Directed DNA Polymerase
1994

Determination of rate and equilibrium binding constants for macromolecular interactions by surface plasmon resonance

O'Shannessy, D. J., Brigham-Burke, M., Karl Soneson, K., Hensley, P. & Brooks, I. A. N., Jan 1 1994, In : Methods in enzymology. 240, C, p. 323-349 27 p.

Research output: Contribution to journalArticle

Surface Plasmon Resonance
Surface plasmon resonance
Optical Phenomena
Light
Cell adhesion

Determination of the Monomer-Dimer Equilibrium of Interleukin-8 Reveals It Is a Monomer at Physiological Concentrations

Burrows, S. D., Doyle, M. L., Murphy, K. P., Franklin, S. G., White, J. R., Brooks, I. S., McNulty, D. E., Scott, M. O., Knutson, J. R., Porter, D., Young, P. R. & Hensley, P., Nov 1 1994, In : Biochemistry. 33, 43, p. 12741-12745 5 p.

Research output: Contribution to journalArticle

Interleukin-8
Dimers
Monomers
Ultracentrifugation
X Ray Crystallography

Determining confidence intervals for parameters derived from analysis of equilibrium analytical ultracentrifugation data

Brooks, I. A. N., Watts, D. G., Karl Soneson, K. & Hensley, P., Jan 1 1994, In : Methods in enzymology. 240, C, p. 459-478 20 p.

Research output: Contribution to journalArticle

Nonlinear Dynamics
Ultracentrifugation
Confidence Intervals
Sedimentation
Rotors

The Soluble Form of E-selectin Is an Asymmetric Monomer: Expression, Purification, and Characterization of the Recombinant Protein

Hensley, P., McDevitt, P. J., Brooks, I. S., Trill, J. J., Feild, J. A., McNulty, D. E., Connor, J. R., Griswold, D. E., Kumar, N. V., Kopple, K. D., Carr, S. A., Dalton, B. J. & Johanson, K., Sep 30 1994, In : Journal of Biological Chemistry. 269, 39, p. 23949-23958 10 p.

Research output: Contribution to journalArticle

E-Selectin
Recombinant Proteins
Purification
Monomers
Molecular Weight
1993

Determination of rate and equilibrium binding constants for macromolecular interactions using surface plasmon resonance: Use of nonlinear least squares analysis methods

O'Shannessy, D. J., Brigham-Burke, M., Karl Soneson, K., Hensley, P. & Brooks, I., Aug 1 1993, In : Analytical Biochemistry. 212, 2, p. 457-468 12 p.

Research output: Contribution to journalArticle

Surface Plasmon Resonance
Surface plasmon resonance
Least-Squares Analysis
Ligands
Rate constants
1992

Use of Protein Unfolding Studies To Determine the Conformational and Dimeric Stabilities of HIV-1 and SIV Proteases

Grant, S. K., Meek, T. D., Deckman, I. C., Debouck, C., Culp, J. S., Minnich, M. D., Brooks, I. S. & Hensley, P., Feb 1 1992, In : Biochemistry. 31, 39, p. 9491-9501 11 p.

Research output: Contribution to journalArticle

Simian Immunodeficiency Virus
Protein Unfolding
Viruses
HIV-1
Peptide Hydrolases
1991

Laue diffraction from protein crystals using a sealed-tube X-ray source

Brooks, I. & Moffat, K., Apr 1 1991, In : Journal of Applied Crystallography. 24, pt 2, p. 146-148 3 p.

Research output: Contribution to journalArticle

X ray tubes
Tungsten
Diffraction patterns
continuous radiation
tungsten