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Research Output 1983 2019

Molecular and cellular characterization of the porcine CD1 family

Chun, T., Wang, K. & Gaskins, H. R., Mar 20 1998, In : FASEB Journal. 12, 5

Research output: Contribution to journalArticle

Swine
Genes
Cosmids
Major Histocompatibility Complex
Molecules

Molecular cloning and characterization of a novel CD1 gene from the pig

Chun, T., Wang, K., Zuckermann, F. A. & Gaskins, H. R., Jun 1 1999, In : Journal of Immunology. 162, 11, p. 6562-6571 10 p.

Research output: Contribution to journalArticle

Molecular Cloning
Swine
Genes
Tail
Cosmids

Molecular ecological analysis of dietary and antibiotic-induced alterations of the mouse intestinal microbiota

McCracken, V. J., Simpson, J. M., Mackie, R. I. & Gaskins, H. R., Jun 21 2001, In : Journal of Nutrition. 131, 6, p. 1862-1870 9 p.

Research output: Contribution to journalArticle

intestinal microorganisms
antibiotics
Anti-Bacterial Agents
Diet
mice

Molecular ecological analysis of fecal bacterial populations from term infants fed formula supplemented with selected blends of prebiotics

Nakamura, N., Gaskins, H. R., Collier, C. T., Nava, G. M., Rai, D., Petschow, B., Russell, W. M., Harris, C., Mackie, R. I., Wampler, J. L. & Walker, D. C., Feb 1 2009, In : Applied and environmental microbiology. 75, 4, p. 1121-1128 8 p.

Research output: Contribution to journalArticle

polydextrose
galactooligosaccharides
Prebiotics
Infant Formula
infant formulas

Molecular ecological analysis of porcine ileal microbiota responses to antimicrobial growth promoters

Collier, C. T., Smiricky-Tjardes, M. R., Albin, D. M., Wubben, J. E., Gabert, V. M., Deplancke, B., Bane, D., Anderson, D. B. & Gaskins, H. R., Dec 1 2003, In : Journal of animal science. 81, 12, p. 3035-3045 11 p.

Research output: Contribution to journalArticle

Microbiota
Tylosin
tylosin
Swine
anti-infective agents

Molecular Ecological Analysis of the Gastrointestinal Microbiota: A Review

Zoetendal, E. G., Collier, C. T., Koike, S., Mackie, R. I. & Gaskins, H. R., Feb 1 2004, In : Journal of Nutrition. 134, 2, p. 465-472 8 p.

Research output: Contribution to journalArticle

Microbiota
Physiological Phenomena
Bacteria
Nutritional Requirements
Population Density

Neither intact nor hydrolyzed soy proteins elicit intestinal inflammation in neonatal piglets

Mcuracken, B. A., Zijlstra, R. T., Donovax, S. M., Odle, J., Lien, E. L. & Rex Gaskins, H., Mar 26 1998, In : Journal of Parenteral and Enteral Nutrition. 22, 2, p. 91-97 7 p.

Research output: Contribution to journalArticle

Soybean Proteins
Caseins
Inflammation
Swine
Milk

New scientific paradigms for probiotics and prebiotics

Reid, G., Sanders, M. E., Gaskins, H. R., Gibson, G. R., Mercenier, A., Rastall, R., Roberfroid, M., Rowland, I., Cherbut, C. & Klaenhammer, T. R., Aug 1 2003, In : Journal of Clinical Gastroenterology. 37, 2, p. 105-118 14 p.

Research output: Contribution to journalArticle

Prebiotics
Probiotics
Nonprofit Organizations
Intestinal Neoplasms
Intestinal Diseases

NIT-1, a pancreatic β-cell line established from a transgenic NOD/Lt mouse

Hamaguchi, K., Gaskins, H. R. & Leiter, E. H., Jul 1991, In : Diabetes. 40, 7, p. 842-849 8 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Transgenic Mice
Cell Line
Interferons
Insulin

On the relationship between sialomucin and sulfomucin expression and hydrogenotrophic microbes in the human colonic mucosa

Croix, J. A., Carbonero, F., Nava, G. M., Russell, M., Greenberg, E. & Gaskins, H. R., Sep 9 2011, In : PloS one. 6, 9, e24447.

Research output: Contribution to journalArticle

Sialomucins
sulfate-reducing bacteria
Sulfates
mucosa
sulfates

Ontogenic and functional analysis of intestinal galectin-3

Baldeón, M. E. & Gaskins, H. R., Mar 20 1998, In : FASEB Journal. 12, 5, p. A873

Research output: Contribution to journalArticle

Galectin 3
Functional analysis
lipopolysaccharides
weaning
epithelial cells

Patient derived glioblastoma cells activate microglia in a three-dimensional gelatin hydrogel

Chen, J. W. E., Lumibao, J., Gaskins, H. R. & Harley, B. A., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hydrogel
Microglia
Gelatin
Glioblastoma
Hydrogels

Phylogenomic analysis of the α proteasome gene family from early-diverging eukaryotes

Bouzatrid, J. L., McNeilrid, L. K., Robertson, H. M., Solter, L. F., Nixon, J. E., Beever, J. E., Gaskins, H. R., Olsen, G. J., Subramaniam, S., Sogin, M. L. & Lewinid, H. A., 2000, In : Journal of Molecular Evolution. 51, 6, p. 532-543 12 p.

Research output: Contribution to journalArticle

proteasome endopeptidase complex
eukaryote
Proteasome Endopeptidase Complex
Eukaryota
eukaryotic cells

Phylomat: An automated protein motif analysis tool for phylogenomics

Graham, W. V., Tcheng, D. K., Shirk, A. L., Attene-Ramos, M. S., Welge, M. & Gaskins, H. R., Nov 1 2004, In : Journal of Proteome Research. 3, 6, p. 1289-1291 3 p.

Research output: Contribution to journalArticle

Amino Acid Motifs
Proteome
Proteins
History
Data Mining

Pig Lmp7 proteasome subunit cDNA cloning and expression analysis

Chun, T., Hermel, E., Aldrich, C. J. & Gaskins, H. R., Jan 26 1999, In : Immunogenetics. 49, 1, p. 72-77 6 p.

Research output: Contribution to journalArticle

Cysteine Endopeptidases
Molecular Sequence Data
Multienzyme Complexes
Amino Acid Sequence Homology
Organ Specificity

Plasticity in the Human Gut Microbiome Defies Evolutionary Constraints

Gomez, A., Sharma, A. K., Mallott, E. K., Petrzelkova, K. J., Jost Robinson, C. A., Yeoman, C. J., Carbonero, F., Pafco, B., Rothman, J. M., Ulanov, A., Vlckova, K., Amato, K. R., Schnorr, S. L., Dominy, N. J., Modry, D., Todd, A., Torralba, M., Nelson, K. E., Burns, M. B., Blekhman, R. & 8 others, Remis, M., Stumpf, R. M., Wilson, B. A., Gaskins, H. R., Garber, P. A., White, B. A., Leigh, S. R. & Mcmahon, K., Jul 31 2019, In : mSphere. 4, 4, 14 p.

Research output: Contribution to journalArticle

Open Access
Microbiota
Primates
Haplorhini
Cercopithecidae
Population

Preliminary results for GAMI: A genetic algorithms approach to motif inference

Congdon, C. B., Fizer, C. W., Smith, N. W., Gaskins, H. R., Aman, J., Nava, G. M. & Mattingly, C., Dec 1 2005, Proceedings of the 2005 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, CIBCB '05. 1594904. (Proceedings of the 2005 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, CIBCB '05; vol. 2005).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Genetic algorithms
Systems analysis
Nucleotides

Prokaryote Diversity of Epithelial Mucosal Biofilms in the Human Digestive Tract

Krause, D. O., Gaskins, H. R. & Mackie, R. I., Nov 30 2007, Biofilms in the Food Environment. Blackwell Publishing Ltd, p. 127-152 26 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Biofilms
Mucus
prokaryotic cells
mucus
digestive tract

Proteasome inhibition alters glucose-stimulated (pro)insulin secretion and turnover in pancreatic β-cells

Kitiphongspattana, K., Mathews, C. E., Leiter, E. H. & Gaskins, H. R., Apr 22 2005, In : Journal of Biological Chemistry. 280, 16, p. 15727-15734 8 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Insulin
Glucose
Tyrosine
Endoplasmic Reticulum

Protective role for nitric oxide during the endoplasmic reticulum stress response in pancreatic β-cells

Kitiphongspattana, K., Khan, T. A., Ishii-Schrade, K., Roe, M. W., Philipson, L. H. & Gaskins, H. R., Jun 1 2007, In : American Journal of Physiology - Endocrinology and Metabolism. 292, 6, p. E1543-E1554

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress
Protein folding
Nitric Oxide
Glutathione Disulfide
Genes

Protein-energy malnutrition (PEM) delays small-intestinal recovery in neonatal pigs infected with rota virus

Zijlstra, R. T., McCracken, B. A., Gaskins, H. R. & Donovan, S. M., 1996, In : FASEB Journal. 10, 3

Research output: Contribution to journalArticle

Protein-Energy Malnutrition
protein energy malnutrition
Viruses
Swine
Recovery

Protein-energy malnutrition delays small-intestinal recovery in neonatal pigs infected with rotavirus

Zijlstra, R. T., Donovan, S. M., Odle, J., Gelberg, H. B., Petschow, B. W. & Gaskins, H. R., Jun 20 1997, In : Journal of Nutrition. 127, 6, p. 1118-1127 10 p.

Research output: Contribution to journalArticle

Protein-Energy Malnutrition
Rotavirus
Swine
Diarrhea
Lactase

Pseudomonas aeruginosa pyocyanin causes airway goblet cell hyperplasia and metaplasia and mucus hypersecretion by inactivating the transcriptional factor FoxA2

Hao, Y., Kuang, Z., Walling, B. E., Bhatia, S., Sivaguru, M., Chen, Y., Gaskins, H. R. & Lau, G., Mar 1 2012, In : Cellular Microbiology. 14, 3, p. 401-415 15 p.

Research output: Contribution to journalArticle

Pyocyanine
Goblet Cells
Metaplasia
Mucus
Pseudomonas aeruginosa

Pseudomonas aeruginosa pyocyanin modulates mucin glycosylation with sialyl-Lewis x to increase binding to airway epithelial cells

Jeffries, J. L., Jia, J., Choi, W., Choe, S., Miao, J., Xu, Y., Powell, R., Lin, J., Kuang, Z., Gaskins, H. R. & Lau, G. W., Jul 1 2016, In : Mucosal Immunology. 9, 4, p. 1039-1050 12 p.

Research output: Contribution to journalArticle

Pyocyanine
Mucins
Glycosylation
Pseudomonas aeruginosa
Epithelial Cells

Pyrosequencing-based analysis of the mucosal microbiota in healthy individuals reveals ubiquitous bacterial groups and micro-heterogeneity

Hong, P. Y., Croix, J. A., Greenberg, E., Gaskins, H. R. & Mackie, R. I., Sep 22 2011, In : PloS one. 6, 9, e25042.

Research output: Contribution to journalArticle

Biopsy
Microbiota
colon
microorganisms
Colon

Race-dependent association of sulfidogenic bacteria with colorectal cancer

Yazici, C., Wolf, P. G., Kim, H., Cross, T. W. L., Vermillion, K., Carroll, T., Augustus, G. J., Mutlu, E., Tussing-Humphreys, L., Braunschweig, C., Xicola, R. M., Jung, B., Llor, X., Ellis, N. A. & Gaskins, H. R., Nov 1 2017, In : Gut. 66, 11, p. 1983-1994 12 p.

Research output: Contribution to journalArticle

African Americans
Colorectal Neoplasms
Bacteria
Mucous Membrane
Bilophila

Redox control of the transsulfuration and glutathione biosynthesis pathways.

Deplancke, B. & Gaskins, H. R., Jan 2002, In : Current opinion in clinical nutrition and metabolic care. 5, 1, p. 85-92 8 p.

Research output: Contribution to journalReview article

Oxidation-Reduction
Glutathione
Cysteine
Reactive Oxygen Species
Sulfur Amino Acids

Regiospecific control of protein expression in cells cultured on two-component counter gradients of extracellular matrix proteins

Gunawan, R. C., Choban, E. R., Conour, J. E., Silvestre, J., Schook, L. B., Gaskins, H. R., Leckband, D. E. & Kenis, P. J. A., Mar 29 2005, In : Langmuir. 21, 7, p. 3061-3068 8 p.

Research output: Contribution to journalArticle

Extracellular Matrix Proteins
cultured cells
counters
Cytology
Immobilized Proteins

Regulation of gene expression during adipocyte differentiation: a review.

Gaskins, H. R., Hausman, G. J. & Martin, R. J., Sep 1989, In : Journal of animal science. 67, 9, p. 2263-2272 10 p.

Research output: Contribution to journalReview article

gene expression regulation
Gene Expression Regulation
adipocytes
Adipocytes
Gene Expression

Regulation of insulin-like growth factor-i ribonucleic acid expression, polypeptide secretion, and binding protein activity by growth hormone in porcine preadipocyte cultures

Gaskins, H. R., Kim, J. W., Wright, J. T., Rund, L. A., Hausman, G. J. & Hausman, G. J., Jan 1990, In : Endocrinology. 126, 1, p. 622-630 9 p.

Research output: Contribution to journalArticle

Somatomedins
Insulin-Like Growth Factor I
Swine
RNA
Peptides

Relationship between Microbiota of the Colonic Mucosa vs Feces and Symptoms, Colonic Transit, and Methane Production in Female Patients with Chronic Constipation

Parthasarathy, G., Chen, J., Chen, X., Chia, N., O'Connor, H. M., Wolf, P. G., Gaskins, H. R. & Bharucha, A. E., Feb 1 2016, In : Gastroenterology. 150, 2, p. 367-379.e1

Research output: Contribution to journalArticle

Microbiota
Methane
Constipation
Feces
Mucous Membrane

Reproducibility of assessing fecal microbiota in chronic constipation

Parthasarathy, G., Chen, J., Chia, N., O'Connor, H. M., Gaskins, H. R. & Bharucha, A. E., Oct 2017, In : Neurogastroenterology and Motility. 29, 10, p. 1-10 10 p.

Research output: Contribution to journalArticle

Microbiota
Constipation
Healthy Volunteers
Laxatives
Energy Intake

Roles of Vibrio fischeri and nonsymbiotic bacteria in the dynamics of mucus secretion during symbiont colonization of the Euprymna scolopes light organ

Nyholm, S. V., Deplancke, B., Gaskins, H. R., Apicella, M. A. & McFall-Ngai, M. J., Oct 1 2002, In : Applied and environmental microbiology. 68, 10, p. 5113-5122 10 p.

Research output: Contribution to journalArticle

Aliivibrio fischeri
Vibrio fischeri
mucus
Mucus
symbiont

Selective growth of mucolytic bacteria including Clostridium perfringens in a neonatal piglet model of total parenteral nutrition

Deplancke, B., Vidal, O., Ganessunker, D., Donovan, S. M., Mackie, R. I. & Gaskins, H. R., Nov 1 2002, In : American Journal of Clinical Nutrition. 76, 5, p. 1117-1125 9 p.

Research output: Contribution to journalArticle

expectorants
Expectorants
Clostridium perfringens
Total Parenteral Nutrition
total parenteral nutrition

Short-term metabolic responses do not differ between neonatal piglets fed formulas containing hydrolyzed or intact soy proteins

Zijlstra, R. T., Mies, A. M., Mccracken, B. A., Odle, J., Gaskins, H. R., Lien, E. L. & Donovan, S. M., Apr 1 1996, In : Journal of Nutrition. 126, 4, p. 913-923 11 p.

Research output: Contribution to journalArticle

Soybean Proteins
feed formulation
soy protein
piglets
protein hydrolysates

Small intestine epithelial barrier function is compromised in pigs with low feed intake at weaning

Spreeuwenberg, M. A. M., Verdonk, J. M. A. J., Gaskins, H. R. & Verstegen, M. W. A., May 21 2001, In : Journal of Nutrition. 131, 5, p. 1520-1527 8 p.

Research output: Contribution to journalArticle

Weaning
Small Intestine
small intestine
Lactose
weaning

Specific-Pathogen-Free Conditions Enhance Inflammatory Bowel Disease in T-Cell Receptor Knockout, but not C3H/HeJBir Mice

Gaskins, H. R., Vondrak-Juergens, G. L., McCracken, B. A. & Woolsey, J. H., Dec 1 1997, In : Laboratory Animal Science. 47, 6, p. 650-655 6 p.

Research output: Contribution to journalArticle

Severity of Illness Index
Rodent Diseases
animal disease models
Specific Pathogen-Free Organisms
Animal Disease Models

Table grape consumption reduces adiposity and markers of hepatic lipogenesis and alters gut microbiota in butter fat-fed mice

Baldwin, J., Collins, B., Wolf, P. G., Martinez, K., Shen, W., Chuang, C. C., Zhong, W., Cooney, P., Cockrell, C., Chang, E., Gaskins, H. R. & McIntosh, M. K., Jan 1 2016, In : Journal of Nutritional Biochemistry. 27, p. 123-135 13 p.

Research output: Contribution to journalArticle

Butter
Lipogenesis
Adiposity
Vitis
Fats

Taurocholic acid metabolism by gut microbes and colon cancer

Ridlon, J. M., Wolf, P. G. & Gaskins, H. R., May 3 2016, In : Gut Microbes. 7, 3, p. 201-215 15 p.

Research output: Contribution to journalReview article

Taurocholic Acid
Bile Acids and Salts
Colonic Neoplasms
Taurine
Bile

Temporal changes of multiple redox couples from proliferation to growth arrest in IEC-6 intestinal epithelial cells

Attene-Ramos, M. S., Kitiphongspattana, K., Ishii-Schrade, K. & Gaskins, H. R., Nov 1 2005, In : American Journal of Physiology - Cell Physiology. 289, 5 58-5, p. C1220-C1228

Research output: Contribution to journalArticle

Oxidation-Reduction
Epithelial Cells
Growth
NAD
Contact Inhibition

The art to science of cell and developmental biology in EBM

Gaskins, H. R., Feb 1 2008, In : Experimental Biology and Medicine. 233, 2, p. 107-108 2 p.

Research output: Contribution to journalEditorial

Cytology
Developmental Biology
Art
Cell Biology

The nonobese diabetic scid mouse: Model for spontaneous thymomagenesis associated with immunodeficiency

Prochazka, M., Gaskins, H. R., Shultz, L. D. & Leiter, E. H., Jan 1 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 8, p. 3290-3294 5 p.

Research output: Contribution to journalArticle

Severe Combined Immunodeficiency
Proviruses
Retroviridae
Mink
Chromosomes, Human, Pair 11

The ‘in vivo lifestyle’ of bile acid 7α-dehydroxylating bacteria: comparative genomics, metatranscriptomic, and bile acid metabolomics analysis of a defined microbial community in gnotobiotic mice

Ridlon, J. M., Devendran, S., Alves, J. M., Doden, H., Wolf, P. G., Pereira, G. V., Ly, L., Volland, A., Takei, H., Nittono, H., Murai, T., Kurosawa, T., Chlipala, G. E., Green, S. J., Hernandez, A. G., Fields, C. J., Wright, C. L., Kakiyama, G., Cann, I., Kashyap, P. & 2 others, McCracken, V. & Gaskins, H. R., Jan 1 2019, In : Gut Microbes.

Research output: Contribution to journalArticle

Germ-Free Life
Metabolomics
Genomics
Bile Acids and Salts
Life Style

Thiol-based antioxidants elicit mitochondrial oxidation via respiratory complex III

Kolossov, V. L., Beaudoin, J. N., Ponnuraj, N., Diliberto, S. J., Hanafin, W. P., Kenis, P. J. A. & Gaskins, H. R., Jul 15 2015, In : American Journal of Physiology - Cell Physiology. 309, 2, p. C81-C91

Research output: Contribution to journalArticle

Electron Transport Complex III
Sulfhydryl Compounds
Antioxidants
Acetylcysteine
Esters

TNF-α sensitizes HT-29 colonic epithelial cells to intestinal lactobacilli

McCracken, V. J., Chun, T., Baldeo, M. E., Ahrne, S., Molin, G., Mackie, R. I. & Gaskins, H. R., Sep 2002, In : Experimental Biology and Medicine. 227, 8, p. 665-670 6 p.

Research output: Contribution to journalArticle

Lactobacillus
Lactobacillus plantarum
Tumor Necrosis Factor-alpha
Epithelial Cells
HT29 Cells
Total Parenteral Nutrition
Colon
Goblet Cells
Lymphocyte Count
Inflammation

Towards interactive visualization for exploring conserved motifs in noncoding DNA sequence

Congdon, C. B., Gaskins, H. R., Nava, G. M. & Mattingly, C., Dec 1 2007, Proceedings of the Frontiers in the Convergence of Bioscience and Information Technologies, FBIT 2007. p. 234-237 4 p. 4524110. (Proceedings of the Frontiers in the Convergence of Bioscience and Information Technologies, FBIT 2007).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

DNA sequences
Visualization
Transcription factors
Binding sites
Computational methods

Transcriptome profiling of the small intestinal epithelium in germfree versus conventional piglets

Chowdhury, S. R., King, D. E., Willing, B. P., Band, M. R., Beever, J. E., Lane, A. B., Loor, J. J., Marini, J. C., Rund, L. A., Schook, L. B., Van Kessel, A. G. & Gaskins, H. R., Jul 5 2007, In : BMC genomics. 8, 215.

Research output: Contribution to journalArticle

Gene Expression Profiling
T Cell Transcription Factor 1
Intestinal Mucosa
Microbiota
Inflammation

Transient light-induced intracellular oxidation revealed by redox biosensor

Kolossov, V. L., Beaudoin, J. N., Hanafin, W. P., DiLiberto, S. J., Kenis, P. J. A. & Gaskins, H. R., Oct 4 2013, In : Biochemical and Biophysical Research Communications. 439, 4, p. 517-521 5 p.

Research output: Contribution to journalArticle

Biosensing Techniques
Biosensors
Oxidation-Reduction
Cells
Glutaredoxins
Heparan Sulfate Proteoglycans
Critical Pathways
Mesoderm
Intestinal Mucosa
Small Intestine