Gregory H Underhill

20012019
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Research Output 2001 2019

  • 24 Article
  • 5 Review article
  • 4 Chapter
  • 1 Conference contribution
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Article
2018

Advances in engineered human liver platforms for drug metabolism studies

Underhill, G. H. & Khetani, S. R., Nov 2018, In : Drug Metabolism and Disposition. 46, 11, p. 1626-1637 12 p.

Research output: Contribution to journalArticle

Liver
Pharmaceutical Preparations
Hepatocytes
Drug Industry
Drug Interactions

Cellular fate decisions in the developing female anteroventral periventricular nucleus are regulated by canonical Notch signaling

Biehl, M. J., Kaylan, K. B., Thompson, R. J., Gonzalez, R. V., Weis, K. E., Underhill, G. H. & Raetzman, L. T., Oct 1 2018, In : Developmental Biology. 442, 1, p. 87-100 14 p.

Research output: Contribution to journalArticle

Anterior Hypothalamus
Kisspeptins
Neurons
Neuroglia
Cell Proliferation

Click Chemistry-Based DNA Labeling of Cells for Barcoding Applications

Gentile, S. D., Griebel, M. E., Anderson, E. W. & Underhill, G. H., Aug 15 2018, In : Bioconjugate Chemistry. 29, 8, p. 2846-2854 9 p.

Research output: Contribution to journalArticle

Click Chemistry
Labeling
DNA
Cell Tracking
Throughput

Spatial patterning of liver progenitor cell differentiation mediated by cellular contractility and Notch signaling

Kaylan, K. B., Berg, I. C., Biehl, M. J., Brougham-Cook, A., Jain, I., Jamil, S. M., Sargeant, L. H., Cornell, N. J., Raetzman, L. T. & Underhill, G. H., Dec 1 2018, In : eLife. 7, e38536.

Research output: Contribution to journalArticle

Liver
Cell Differentiation
Stem Cells
Cues
Hepatocytes
2017

A high-throughput cell microarray platform for correlative analysis of cell differentiation and traction forces

Kaylan, K. B., Kourouklis, A. P. & Underhill, G. H., Mar 1 2017, In : Journal of Visualized Experiments. 2017, 121, e55362.

Research output: Contribution to journalArticle

Traction
Microarrays
Cell Differentiation
Hydrogel
Throughput

Substrate stiffness and VE-cadherin mechano-transduction coordinate to regulate endothelial monolayer integrity

Andresen Eguiluz, R. C., Kaylan, K. B., Underhill, G. H. & Leckband, D. E., Sep 2017, In : Biomaterials. 140, p. 45-57 13 p.

Research output: Contribution to journalArticle

Signal transduction
Rigidity
Monolayers
Stiffness
Signal Transduction
2016

Combinatorial microenvironmental regulation of liver progenitor differentiation by Notch ligands, TGFβ, and extracellular matrix

Kaylan, K. B., Ermilova, V., Yada, R. C. & Underhill, G. H., Mar 30 2016, In : Scientific Reports. 6, 23490.

Research output: Contribution to journalArticle

Extracellular Matrix
Ligands
Liver
Collagen
Stem Cells

Extracellular matrix microarrays to study inductive signaling for endoderm specification

Malta, D. F. B., Reticker-Flynn, N. E., Da Silva, C. L., Cabral, J. M. S., Fleming, H. E., Zaret, K. S., Bhatia, S. N. & Underhill, G. H., Apr 1 2016, In : Acta Biomaterialia. 34, p. 30-40 11 p.

Research output: Contribution to journalArticle

Endoderm
Microarrays
Extracellular Matrix
Specifications
Stem Cells

Mapping lung tumor cell drug responses as a function of matrix context and genotype using cell microarrays

Kaylan, K. B., Gentile, S. D., Milling, L. E., Bhinge, K. N., Kosari, F. & Underhill, G. H., Dec 2016, In : Integrative Biology (United Kingdom). 8, 12, p. 1221-1231 11 p.

Research output: Contribution to journalArticle

Microarrays
Tumors
Genotype
Cells
Extracellular Matrix Proteins

Substrate stiffness and matrix composition coordinately control the differentiation of liver progenitor cells

Kourouklis, A. P., Kaylan, K. B. & Underhill, G. H., Aug 1 2016, In : Biomaterials. 99, p. 82-94 13 p.

Research output: Contribution to journalArticle

Liver
Extracellular Matrix
Stem Cells
Stiffness
Traction
2012

A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis

Reticker-Flynn, N. E., Malta, D. F. B., Winslow, M. M., Lamar, J. M., Xu, M. J., Underhill, G. H., Hynes, R. O., Jacks, T. E. & Bhatia, S. N., Nov 26 2012, In : Nature communications. 3, 1122.

Research output: Contribution to journalArticle

metastasis
Integrins
Extracellular Matrix
Tumors
Adhesion
2010

Microfluidics-integrated time-lapse imaging for analysis of cellular dynamics

Albrecht, D. R., Underhill, G. H., Resnikoff, J., Mendelson, A., Bhatia, S. N. & Shah, J. V., Jun 16 2010, In : Integrative Biology. 2, 5-6, p. 278-287 10 p.

Research output: Contribution to journalArticle

Time-Lapse Imaging
Microfluidics
Imaging techniques
Cells
Cellular Microenvironment

Multiplexed, high-throughput analysis of 3D microtissue suspensions

Chen, A. A., Underhill, G. H. & Bhatia, S. N., Oct 1 2010, In : Integrative Biology. 2, 10, p. 517-527 11 p.

Research output: Contribution to journalArticle

Suspensions
Throughput
Tissue
Hepatocellular Carcinoma
Functional assessment
2009

Microenvironmental regulation of the sinusoidal endothelial cell phenotype in vitro

March, S., Hui, E. E., Underhill, G. H., Khetani, S. & Bhatia, S. N., Nov 27 2009, In : Hepatology. 50, 3, p. 920-928 9 p.

Research output: Contribution to journalArticle

Endothelial Cells
Phenotype
Liver
Collagen
Extracellular Matrix
2007

Assessment of hepatocellular function within PEG hydrogels

Underhill, G. H., Chen, A. A., Albrecht, D. R. & Bhatia, S. N., Jan 1 2007, In : Biomaterials. 28, 2, p. 256-270 15 p.

Research output: Contribution to journalArticle

Hydrogels
Liver
Polyethylene glycols
Hepatocytes
Hydrogel

Multiphase electropatterning of cells and biomaterials

Albrecht, D. R., Underhill, G. H., Mendelson, A. & Bhatia, S. N., Jan 1 2007, In : Lab on a chip. 7, 6, p. 702-709 8 p.

Research output: Contribution to journalArticle

Biocompatible Materials
Biomaterials
Tissue
Hydrogels
Hydrogel
2006

Probing the role of multicellular organization in three-dimensional microenvironments

Albrecht, D. R., Underhill, G. H., Wassermann, T. B., Sah, R. L. & Bhatia, S. N., May 1 2006, In : Nature Methods. 3, 5, p. 369-375 7 p.

Research output: Contribution to journalArticle

Hydrogel
Tissue
Cells
Biosynthesis
Regenerative Medicine
2005

A crucial role for T-bet in selectin ligand expression in T helper 1 (Th1) cells

Underhill, G. H., Zisoulis, D. G., Kolli, K. P., Ellies, L. G., Marth, J. D. & Kansas, G. S., Dec 1 2005, In : Blood. 106, 12, p. 3867-3873 7 p.

Research output: Contribution to journalArticle

Selectins
Th1 Cells
Ligands
beta-galactoside alpha-2,3-sialyltransferase
P-Selectin
2003

Complexity within the plasma cell compartment of mice deficient in both E- and P-selectin: Implications for plasma cell differentiation

Underhill, G. H., Kolli, K. P. & Kansas, G. S., Dec 1 2003, In : Blood. 102, 12, p. 4076-4083 8 p.

Research output: Contribution to journalArticle

P-Selectin
E-Selectin
Plasma Cells
Cell Differentiation
Plasmas

Gene expression profiling reveals a highly specialized genetic program of plasma cells

Underhill, G. H., George, D., Bremer, E. G. & Kansas, G. S., May 15 2003, In : Blood. 101, 10, p. 4013-4021 9 p.

Research output: Contribution to journalArticle

Gene Expression Profiling
Plasma Cells
Gene expression
Plasmas
Cell Differentiation
2002

IgG plasma cells display a unique spectrum of leukocyte adhesion and homing molecules

Underhill, G. H., Minges-Wols, H. A., Fornek, J. L., Witte, P. L. & Kansas, G. S., Apr 15 2002, In : Blood. 99, 8, p. 2905-2912 8 p.

Research output: Contribution to journalArticle

Cell Adhesion Molecules
Plasma Cells
Adhesion
Immunoglobulin G
Plasmas

Sialyltransferase specificity in selectin ligand formation

Ellies, L. G., Sperandio, M., Underhill, G. H., Yousif, J., Smith, M., Priatel, J. J., Kansas, G. S., Ley, K. & Marth, J. D., Nov 15 2002, In : Blood. 100, 10, p. 3618-3625 8 p.

Research output: Contribution to journalArticle

beta-galactoside alpha-2,3-sialyltransferase
Sialyltransferases
Selectins
Ligands
E-Selectin

The role of bone marrow-derived stromal cells in the maintenance of plasma cell longevity

Minges Wols, H. A., Underhill, G. H., Kansas, G. S. & Witte, P. L., Oct 15 2002, In : Journal of Immunology. 169, 8, p. 4213-4221 9 p.

Research output: Contribution to journalArticle

Plasma Cells
Mesenchymal Stromal Cells
Maintenance
Stromal Cells
Coculture Techniques
2001

Cutting edge: Differential requirements for Stat4 in expression of glycosyltransferases responsible for selectin ligand formation in Th1 cells

White, S. J., Underhill, G. H., Kaplan, M. H. & Kansas, G. S., Jul 15 2001, In : Journal of Immunology. 167, 2, p. 628-631 4 p.

Research output: Contribution to journalArticle

Selectins
Glycosyltransferases
Th1 Cells
galactoside 3-fucosyltransferase
Interleukin-12