Gireesh Rajashekara

2024

Escherichia coli isolates from vegetable farms in Addis Ababa, Ethiopia: Antimicrobial susceptibility profile and associated resistance genetic markers

Hailu, W., Alemayehu, H., Hailu, L., Medhin, G., Rajashekara, G., Gebreyes, W. A. & Eguale, T., Jun 2024, In: Food Science and Nutrition. 12, 6, p. 4122-4132 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Identification of novel small molecule inhibitors of twin arginine translocation (Tat) pathway and their effect on the control of Campylobacter jejuni in chickens

Deblais, L., Drozd, M., Kumar, A., Antwi, J., Fuchs, J., Khupse, R., Helmy, Y. A. & Rajashekara, G., 2024, In: Frontiers in Microbiology. 15, 1342573.

Research output: Contribution to journal › Article › peer-review

Open Access

Impact of Irrigation Source on the Dissemination and Persistence of Coliforms and Foodborne Pathogens in Fresh Tomato High Tunnel-dripline System from Small Specialty Crop Farms

Deblais, L., Kauffman, M. & Rajashekara, G., Dec 2024, In: Journal of Food Protection. 87, 12, 100382.

Research output: Contribution to journal › Article › peer-review

Open Access

In vitro, in planta, and comparative genomic analyses of Pseudomonas syringae pv. syringae strains of pepper (Capsicum annuum var. annuum)

Ranjit, S., Deblais, L., Poelstra, J. W., Bhandari, M., Rotondo, F., Scaria, J., Miller, S. A. & Rajashekara, G., Jun 2024, In: Microbiology Spectrum. 12, 6

Research output: Contribution to journal › Article › peer-review

Open Access

Triazole resistance in Aspergillus fumigatus isolated from a tomato production environment exposed to propiconazole

Jimenez Madrid, A. M., Paul, R. A., Rotondo, F., Deblais, L., Rajashekara, G., Miller, S. A. & Lewis Ivey, M. L., Apr 2024, In: Applied and environmental microbiology. 90, 4

Research output: Contribution to journal › Article › peer-review

2023

A longitudinal study to examine the influence of farming practices and environmental factors on pathogen prevalence using structural equation modeling

Ferguson, M., Hsu, C. K., Grim, C., Kauffman, M., Jarvis, K., Pettengill, J. B., Babu, U. S., Harrison, L. M., Li, B., Hayford, A., Balan, K. V., Freeman, J. P., Rajashekara, G., Lipp, E. K., Rozier, R. S., Zimeri, A. M. & Burall, L. S., 2023, In: Frontiers in Microbiology. 14, 1141043.

Research output: Contribution to journal › Article › peer-review

Open Access

Anti-rotavirus Properties and Mechanisms of Selected Gram-Positive and Gram-Negative Probiotics on Polarized Human Colonic (HT-29) Cells

Kumar, A., Helmy, Y. A., Fritts, Z., Vlasova, A., Saif, L. J. & Rajashekara, G., Feb 2023, In: Probiotics and Antimicrobial Proteins. 15, 1, p. 107-128 22 p.

Research output: Contribution to journal › Article › peer-review

Discovery of Novel Small Molecule Growth Inhibitors to Manage Pseudomonas Leaf Spot Disease on Peppers (Capsicum sp.)

Ranjit, S., Deblais, L., Rotondo, F., Shannon, B., Johnson, R., Miller, S. A. & Rajashekara, G., Nov 2023, In: Plant disease. 107, 11, p. 3560-3574 15 p.

Research output: Contribution to journal › Article › peer-review

Efficacy of quorum sensing and growth inhibitors alone and in combination against avian pathogenic Escherichia coli infection in chickens

Helmy, Y. A., Kathayat, D., Closs, G., Galgozy, K., Fuchs, J. R. & Rajashekara, G., Apr 2023, In: Poultry science. 102, 4, 102543.

Research output: Contribution to journal › Article › peer-review

Open Access

Genomic Diversity, Antimicrobial Resistance, Plasmidome, and Virulence Profiles of Salmonella Isolated from Small Specialty Crop Farms Revealed by Whole-Genome Sequencing

Bhandari, M., Poelstra, J. W., Kauffman, M., Varghese, B., Helmy, Y. A., Scaria, J. & Rajashekara, G., Nov 2023, In: Antibiotics. 12, 11, 1637.

Research output: Contribution to journal › Article › peer-review

Open Access

Prevalence and Load of the Campylobacter Genus in Infants and Associated Household Contacts in Rural Eastern Ethiopia: a Longitudinal Study from the Campylobacter Genomics and Environmental Enteric Dysfunction (CAGED) Project

Deblais, L., Ojeda, A., Brhane, M., Mummed, B., Hassen, K. A., Ahmedo, B. U., Weldesenbet, Y. D., Amin, J. K., Ahmed, I. A., Usmane, I. A., Yusuf, E. A., Seran, A. J., Abrahim, F. I., Game, H. T., Mummed, B. A., Usmail, M. M., Umer, K. A., Dawid, M. M., Gebreyes, W. & French, N. & 11 others, Hassen, J. Y., Roba, K. T., Mohammed, A., Yimer, G., Saleem, C., Chen, D., Singh, N., Manary, M. J., McKune, S. L., Havelaar, A. H. & Rajashekara, G., Jul 2023, In: Applied and environmental microbiology. 89, 7

Research output: Contribution to journal › Article › peer-review

Open Access

Role of Stress-Induced Proteins RpoS and YicC in the Persistence of Salmonella enterica subsp. enterica Serotype Typhimurium in Tomato Plants

Deblais, L., Ranjit, S., Vrisman, C., Antony, L., Scaria, J., Sally, A. M. & Rajashekara, G., Mar 2023, In: Molecular Plant-Microbe Interactions. 36, 2, p. 109-118 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Strategies for the Preparation of Chitosan Derivatives for Antimicrobial, Drug Delivery, and Agricultural Applications: A Review

Shrestha, R., Thenissery, A., Khupse, R. & Rajashekara, G., Nov 2023, In: Molecules. 28, 22, 7659.

Research output: Contribution to journal › Review article › peer-review

Open Access

Whole genome characterization of thermophilic Campylobacter species isolated from dairy manure in small specialty crop farms of Northeast Ohio

Deblais, L., Jang, H., Kauffman, M., Gangiredla, J., Sawyer, M., Basa, S., Poelstra, J. W., Babu, U. S., Harrison, L. M., Hiett, K. L., Balan, K. V. & Rajashekara, G., 2023, In: Frontiers in Microbiology. 14, 1074548.

Research output: Contribution to journal › Article › peer-review

Open Access

Women’s empowerment and child nutrition in a context of shifting livelihoods in Eastern Oromia, Ethiopia

Mechlowitz, K., Singh, N., Li, X., Chen, D., Yang, Y., Rabil, A., Cheraso, A. J., Ahmed, I. A., Amin, J. K., Gebreyes, W. A., Hassen, J. Y., Ibrahim, A. M., Manary, M. J., Rajashekara, G., Roba, K. T., Usmane, I. A., Havelaar, A. H. & McKune, S. L., 2023, In: Frontiers in Nutrition. 10, 1048532.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

Effect of Probiotic E. coli Nissle 1917 Supplementation on the Growth Performance, Immune Responses, Intestinal Morphology, and Gut Microbes of Campylobacter jejuni Infected Chickens

Helmy, Y. A., Closs, G., Jung, K., Kathayat, D., Vlasova, A. & Rajashekara, G., Oct 2022, In: Infection and immunity. 90, 10

Research output: Contribution to journal › Article › peer-review

Open Access

Escherichia coli Nissle 1917 Enhances Efficacy of Oral Attenuated Human Rotavirus Vaccine in a Gnotobiotic Piglet Model

Michael, H., Miyazaki, A., Langel, S. N., Amimo, J. O., Kick, M. K., Chepngeno, J., Paim, F. C., Fischer, D. D., Rajashekara, G., Saif, L. J. & Vlasova, A. N., Jan 2022, In: Vaccines. 10, 1, 83.

Research output: Contribution to journal › Article › peer-review

Open Access

Evaluation of Novel Quorum Sensing Inhibitors Targeting Auto-Inducer 2 (AI-2) for the Control of Avian Pathogenic Escherichia coli Infections in Chickens

Helmy, Y. A., Kathayat, D., Deblais, L., Srivastava, V., Closs, G., Tokarski, R. J., Ayinde, O., Fuchs, J. R. & Rajashekara, G., Jun 2022, In: Microbiology Spectrum. 10, 3

Research output: Contribution to journal › Article › peer-review

Open Access

Gut Microbiota of Obese Children Influences Inflammatory Mucosal Immune Pathways in the Respiratory Tract to Influenza Virus Infection: Optimization of an Ideal Duration of Microbial Colonization in a Gnotobiotic Pig Model

Renu, S., Deblais, L., Patil, V., Schrock, J., Kathayat, D., Srivastava, V., Feliciano-Ruiz, N., Han, Y., Ramesh, A., Lakshmanappa, Y. S., Ghimire, S., Dhakal, S., Rajashekara, G. & Renukaradhya, G. J., Jun 2022, In: Microbiology Spectrum. 10, 3

Research output: Contribution to journal › Article › peer-review

Open Access

Identification and Subtyping of Salmonella Isolates Using Matrix-Assisted Laser Desorption–Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF)

Persad, A. K., Fahmy, H. A., Anderson, N., Cui, J., Topalcengiz, Z., Jeamsripong, S., Spanninger, P. M., Buchanan, R. L., Kniel, K. E., Jay-Russell, M. T., Danyluk, M. D., Rajashekara, G. & Lejeune, J. T., Apr 2022, In: Microorganisms. 10, 4, 688.

Research output: Contribution to journal › Article › peer-review

Open Access

In Vitro and In Vivo Evaluation of Lacticaseibacillus rhamnosus GG and Bifidobacterium lactis Bb12 Against Avian Pathogenic Escherichia coli and Identification of Novel Probiotic-Derived Bioactive Peptides

Kathayat, D., Closs, G., Helmy, Y. A., Deblais, L., Srivastava, V. & Rajashekara, G., Dec 2022, In: Probiotics and Antimicrobial Proteins. 14, 6, p. 1012-1028 17 p.

Research output: Contribution to journal › Article › peer-review

Mechanisms of Kwashiorkor-Associated Immune Suppression: Insights From Human, Mouse, and Pig Studies

Michael, H., Amimo, J. O., Rajashekara, G., Saif, L. J. & Vlasova, A. N., May 2 2022, In: Frontiers in immunology. 13, 826268.

Research output: Contribution to journal › Review article › peer-review

Open Access

Shiga toxin (stx) encoding genes in sheep and goats reared in Trinidad and Tobago

Persad, A. K., Rajashekara, G. & LeJeune, J. T., Nov 2022, In: PloS one. 17, 11 November, e0277564.

Research output: Contribution to journal › Article › peer-review

Open Access

The Combined Escherichia coli Nissle 1917 and Tryptophan Treatment Modulates Immune and Metabolome Responses to Human Rotavirus Infection in a Human Infant Fecal Microbiota-Transplanted Malnourished Gnotobiotic Pig Model

Michael, H., Srivastava, V., Deblais, L., Amimo, J. O., Chepngeno, J., Saif, L. J., Rajashekara, G. & Vlasova, A. N., Sep 2022, In: mSphere. 7, 5

Research output: Contribution to journal › Article › peer-review

Open Access

Unravelling the reservoirs for colonisation of infants with Campylobacter spp. in rural Ethiopia: protocol for a longitudinal study during a global pandemic and political tensions

Havelaar, A. H., Brhane, M., Ahmed, I. A., Kedir, J., Chen, D., Deblais, L., French, N., Gebreyes, W. A., Hassen, J. Y., Li, X., Manary, M. J., Mekuria, Z., Ibrahim, A. M., Mummed, B., Ojeda, A., Rajashekara, G., Roba, K. T., Saleem, C., Singh, N. & Usmane, I. A. & 3 others, Yang, Y., Yimer, G. & McKune, S., Oct 5 2022, In: BMJ Open. 12, 10, e061311.

Research output: Contribution to journal › Article › peer-review

Open Access

2021

A cross-sectional study of the nasal and fecal microbiota of sows from different health status within six commercial swine farms

Arruda, A. G., Deblais, L., Hale, V. L., Madden, C., Pairis-Garcia, M., Srivastava, V., Kathayat, D., Kumar, A. & Rajashekara, G., Sep 2021, In: PeerJ. 9, e12120.

Research output: Contribution to journal › Article › peer-review

Open Access

Avian pathogenic escherichia coli (Apec): An overview of virulence and pathogenesis factors, zoonotic potential, and control strategies

Kathayat, D., Lokesh, D., Ranjit, S. & Rajashekara, G., 2021, In: Pathogens. 10, 4, 467.

Research output: Contribution to journal › Review article › peer-review

Open Access

Bioluminescent Xanthomonas hortorum pv. gardneri as a Tool to Quantify Bacteria in Planta, Screen Germplasm, and Identify Infection Routes on Leaf Surfaces

Bernal, E., Deblais, L., Rajashekara, G. & Francis, D. M., Jun 15 2021, In: Frontiers in Plant Science. 12, 667351.

Research output: Contribution to journal › Article › peer-review

Open Access

Campylobacter Colonization, Environmental Enteric Dysfunction, Stunting, and Associated Risk Factors Among Young Children in Rural Ethiopia: A Cross-Sectional Study From the Campylobacter Genomics and Environmental Enteric Dysfunction (CAGED) Project

Chen, D., McKune, S. L., Singh, N., Yousuf Hassen, J., Gebreyes, W., Manary, M. J., Bardosh, K., Yang, Y., Diaz, N., Mohammed, A., Terefe, Y., Roba, K. T., Ketema, M., Ameha, N., Assefa, N., Rajashekara, G., Deblais, L., Ghanem, M., Yimer, G. & Havelaar, A. H., Jan 21 2021, In: Frontiers in Public Health. 8, 615793.

Research output: Contribution to journal › Article › peer-review

Open Access

Compound prioritization through meta-analysis enhances the discovery of antimicrobial hits against bacterial pathogens

Deblais, L. & Rajashekara, G., Sep 2021, In: Antibiotics. 10, 9, 1065.

Research output: Contribution to journal › Article › peer-review

Open Access

Escherichia coli Nissle 1917 administered as a dextranomar microsphere biofilm enhances immune responses against human rotavirus in a neonatal malnourished pig model colonized with human infant fecal microbiota

Michael, H., Paim, F. C., Miyazaki, A., Langel, S. N., Fischer, D. D., Chepngeno, J., Goodman, S. D., Rajashekara, G., Saif, L. J. & Vlasova, A. N., Feb 2021, In: PloS one. 16, 2 February, e0246193.

Research output: Contribution to journal › Article › peer-review

Open Access

Escherichia coli Nissle 1917 Enhances Innate and Adaptive Immune Responses in a Ciprofloxacin-Treated Defined-Microbiota Piglet Model of Human Rotavirus Infection

Michael, H., Paim, F. C., Langel, S. N., Miyazaki, A., Fischer, D. D., Chepngeno, J., Amimo, J., Deblais, L., Rajashekara, G., Saif, L. J. & Vlasova, A. N., Mar 2021, In: mSphere. 6, 2, p. 1-16 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Immuno-modulatory effect of probiotic E. coli Nissle 1917 in polarized human colonic cells against Campylobacter jejuni infection

Helmy, Y. A., Kassem, I. I. & Rajashekara, G., 2021, In: Gut Microbes. 13, 1, p. 1-16 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Impact of Plant Pathogen Infection on Salmonella enterica subsp. enterica Serotype Typhimurium Persistence in Tomato Plants

DEBLAIS, L., MILLER, S. A. & Rajashekara, G., Apr 2021, In: Journal of Food Protection. 84, 4, p. 563-571 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Novel small molecule growth inhibitor affecting bacterial outer membrane reduces extraintestinal pathogenic escherichia coli (ExPEC) infection in avian model

Kathayat, D., Helmy, Y. A., Deblais, L., Srivastava, V., Closs, G., Khupse, R. & Rajashekara, G., Oct 2021, In: Microbiology Spectrum. 9, 2, e00006-21.

Research output: Contribution to journal › Article › peer-review

Open Access

Novel small molecule growth inhibitors of xanthomonas spp. causing bacterial spot of tomato

Srivastava, V., Deblais, L., Kathayat, D., Rotondo, F., Helmy, Y. A., Miller, S. A. & Rajashekara, G., Jun 2021, In: Phytopathology. 111, 6, p. 940-953 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Peptides Affecting the Outer Membrane Lipid Asymmetry System (MlaA-OmpC/F) Reduce Avian Pathogenic Escherichia coli (APEC) Colonization in Chickens

Kathayat, D., Closs, G., Helmy, Y. A., Lokesh, D., Ranjit, S. & Rajashekara, G., Aug 2021, In: Applied and environmental microbiology. 87, 17, p. 1-22 22 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Prevalence and Antimicrobial Resistance Profiles of Foodborne Pathogens Isolated from Dairy Cattle and Poultry Manure Amended Farms in Northeastern Ohio, the United States

Hailu, W., Helmy, Y. A., Carney-Knisely, G., Kauffman, M., Fraga, D. & Rajashekara, G., Dec 2021, In: Antibiotics. 10, 12, 1450.

Research output: Contribution to journal › Article › peer-review

Open Access

2020

Co-occurrence of Campylobacter Species in Children From Eastern Ethiopia, and Their Association With Environmental Enteric Dysfunction, Diarrhea, and Host Microbiome

Terefe, Y., Deblais, L., Ghanem, M., Helmy, Y. A., Mummed, B., Chen, D., Singh, N., Ahyong, V., Kalantar, K., Yimer, G., Yousuf Hassen, J., Mohammed, A., McKune, S. L., Manary, M. J., Ordiz, M. I., Gebreyes, W., Havelaar, A. H. & Rajashekara, G., Apr 15 2020, In: Frontiers in Public Health. 8, 99.

Research output: Contribution to journal › Article › peer-review

Open Access

Discovery and characterization of low-molecular weight inhibitors of Erwinia tracheiphila

Vrisman, C. M., Deblais, L., Helmy, Y. A., Johnson, R., Rajashekara, G. & Miller, S. A., May 2020, In: Phytopathology. 110, 5, p. 989-998 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

High-throughput screening reveals small molecule modulators inhibitory to Acidovorax citrulli

Lu, Y., Deblais, L., Rajashekara, G., Miller, S. A., Helmy, Y. A., Zhang, H., Wu, P., Qiu, Y. & Xu, X., Jun 1 2020, In: Plant Pathology. 69, 5, p. 818-826 9 p.

Research output: Contribution to journal › Article › peer-review

Identification and characterization of novel small molecule inhibitors to control Mycoplasma gallisepticum infection in chickens

Helmy, Y. A., Kathayat, D., Ghanem, M., Jung, K., Closs, G., Deblais, L., Srivastava, V., El-Gazzar, M. & Rajashekara, G., Aug 2020, In: Veterinary Microbiology. 247, 108799.

Research output: Contribution to journal › Article › peer-review

Open Access

Malnutrition Decreases Antibody Secreting Cell Numbers Induced by an Oral Attenuated Human Rotavirus Vaccine in a Human Infant Fecal Microbiota Transplanted Gnotobiotic Pig Model

Michael, H., Langel, S. N., Miyazaki, A., Paim, F. C., Chepngeno, J., Alhamo, M. A., Fischer, D. D., Srivastava, V., Kathayat, D., Deblais, L., Rajashekara, G., Saif, L. J. & Vlasova, A. N., Feb 14 2020, In: Frontiers in immunology. 11, 196.

Research output: Contribution to journal › Article › peer-review

Open Access

Reduced rotavirus vaccine efficacy in protein malnourished human-faecal-microbiota-transplanted gnotobiotic pig model is in part attributed to the gut microbiota

Srivastava, V., Deblais, L., Huang, H. C., Miyazaki, A., Kandasamy, S., Langel, S. N., Paim, F. C., Chepngeno, J., Kathayat, D., Vlasova, A. N., Saif, L. J. & Rajashekara, G., 2020, In: Beneficial Microbes. 11, 8, p. 733-751 19 p.

Research output: Contribution to journal › Article › peer-review

Small molecule adjuvants potentiate colistin activity and attenuate resistance development in escherichia coli by affecting pmrab system

Kathayat, D., Antony, L., Deblais, L., Helmy, Y. A., Scaria, J. & Rajashekara, G., 2020, In: Infection and Drug Resistance. 13, p. 2205-2222 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Translating 'big data': Better understanding of host-pathogen interactions to control bacterial foodborne pathogens in poultry

Deblais, L., Kathayat, D., Helmy, Y. A., Closs, G. & Rajashekara, G., Jun 1 2020, In: Animal Health Research Reviews. 21, 1, p. 15-35 21 p.

Research output: Contribution to journal › Review article › peer-review

2019

How the gut microbiome regulates host immune responses to viral vaccines

Vlasova, A. N., Takanashi, S., Miyazaki, A., Rajashekara, G. & Saif, L. J., Aug 2019, In: Current Opinion in Virology. 37, p. 16-25 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

Imidazole and methoxybenzylamine growth inhibitors reduce salmonella persistence in tomato plant tissues

Deblais, L., Vrisman, C., Kathayat, D., Helmy, Y. A., Miller, S. A. & Rajashekara, G., Jun 2019, In: Journal of Food Protection. 82, 6, p. 997-1006 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Novel narrow spectrum benzyl thiophene sulfonamide derivatives to control Campylobacter

Deblais, L., Helmy, Y. A., Kumar, A., Antwi, J., Kathayat, D., Acuna, U. M., Huang, H. C., de Blanco, E. C., Fuchs, J. R. & Rajashekara, G., Jul 1 2019, In: Journal of Antibiotics. 72, 7, p. 555-565 11 p.

Research output: Contribution to journal › Article › peer-review

Specific environmental temperature and relative humidity conditions and grafting affect the persistence and dissemination of Salmonella enterica subsp. enterica serotype Typhimurium in tomato plant tissues

Deblais, L., Helmy, Y. A., Testen, A., Vrisman, C., Madrid, A. M. J., Kathayat, D., Miller, S. A. & Rajashekara, G., Jun 1 2019, In: Applied and environmental microbiology. 85, 11, e00403-19.

Research output: Contribution to journal › Article › peer-review

Open Access

Gireesh Rajashekara

Research output

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