Fan Lam

2025

Joint learning of nonlinear representation and projection for fast constrained MRSI reconstruction

Li, Y., Ruhm, L., Wang, Z., Zhao, R., Anderson, A., Arnold, P., Huesmann, G., Henning, A. & Lam, F., Feb 2025, In: Magnetic Resonance in Medicine. 93, 2, p. 455-469 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2024

Denoising of 3D Magnetic resonance images based on balanced low-rank tensor and nonlocal self-similarity

Liu, X., He, J., Gao, P., Abdelmounim, B. & Lam, F., Oct 2024, In: Biomedical Signal Processing and Control. 96, 106588.

Research output: Contribution to journal › Article › peer-review

High-Dimensional MR Reconstruction Integrating Subspace and Adaptive Generative Models

Zhao, R., Peng, X., Kelkar, V. A., Anastasio, M. A. & Lam, F., Jun 1 2024, In: IEEE Transactions on Biomedical Engineering. 71, 6, p. 1969-1979 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

High-resolution ¹H-MRSI at 9.4 T by integrating relaxation enhancement and subspace imaging

Wang, Y., Saha, U., Rubakhin, S. S., Roy, E. J., Smith, A. M., Sweedler, J. V. & Lam, F., Oct 2024, In: NMR in Biomedicine. 37, 10, e5161.

Research output: Contribution to journal › Article › peer-review

Open Access

Multi-Parametric Molecular Imaging of the Brain Using Optimized Multi-TE Subspace MRSI

Wang, Z., Li, Y., Cao, C., Anderson, A., Huesmann, G. & Lam, F., Jun 1 2024, In: IEEE Transactions on Biomedical Engineering. 71, 6, p. 1732-1744 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Multiscale biochemical mapping of the brain through deep-learning-enhanced high-throughput mass spectrometry

Xie, Y. R., Castro, D. C., Rubakhin, S. S., Trinklein, T. J., Sweedler, J. V. & Lam, F., Mar 2024, In: Nature Methods. 21, 3, p. 521-530 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

High-Dimensional MR Spatiospectral Imaging by Integrating Physics-Based Modeling and Data-Driven Machine Learning: Current progress and future directions

Lam, F., Peng, X. & Liang, Z. P., Mar 1 2023, In: IEEE Signal Processing Magazine. 40, 2, p. 101-115 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

DeepSENSE: Learning coil sensitivity functions for SENSE reconstruction using deep learning

Peng, X., Sutton, B. P., Lam, F. & Liang, Z. P., Apr 2022, In: Magnetic Resonance in Medicine. 87, 4, p. 1894-1902 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Enhancing the Throughput of FT Mass Spectrometry Imaging Using Joint Compressed Sensing and Subspace Modeling

Xie, Y. R., Castro, D. C., Rubakhin, S. S., Sweedler, J. V. & Lam, F., Apr 5 2022, In: Analytical Chemistry. 94, 13, p. 5335-5343 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Epigenetic MRI: Noninvasive imaging of DNA methylation in the brain

Lam, F., Chu, J., Choi, J. S., Cao, C., Hitchens, T. K., Silverman, S. K., Liang, Z.-P., Dilger, R. N., Robinson, G. E. & Li, K. C., Mar 8 2022, In: Proceedings of the National Academy of Sciences. 119, 10, e2119891119.

Research output: Contribution to journal › Article › peer-review

Open Access

High-resolution, 3D multi-TE ¹H MRSI using fast spatiospectral encoding and subspace imaging

Wang, Z., Li, Y. & Lam, F., Mar 2022, In: Magnetic Resonance in Medicine. 87, 3, p. 1103-1118 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

SNR Enhancement for Multi-TE MRSI Using Joint Low-Dimensional Model and Spatial Constraints

Li, Y., Wang, Z. & Lam, F., Oct 1 2022, In: IEEE Transactions on Biomedical Engineering. 69, 10, p. 3087-3097 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Ultra-High-Field MRI in the Diagnosis and Management of Gliomas: A Systematic Review

Shaffer, A., Kwok, S. S., Naik, A., Anderson, A. T., Lam, F., Wszalek, T., Arnold, P. M. & Hassaneen, W., Apr 5 2022, In: Frontiers in Neurology. 13, 857825.

Research output: Contribution to journal › Review article › peer-review

Open Access

2021

Separation of Metabolites and Macromolecules for Short-TE ¹H-MRSI Using Learned Component-Specific Representations

Li, Y., Wang, Z., Sun, R. & Lam, F., Apr 2021, In: IEEE transactions on medical imaging. 40, 4, p. 1157-1167 11 p., 9312607.

Research output: Contribution to journal › Article › peer-review

Open Access

System and method for ultrafast magnetic resonance spectroscopic imaging using learned spectral features

Lam, F. (Inventor) & Liang, Z.-P. (Inventor), Aug 3 2021, U.S. Patent No. 11079453, Aug 23 2018

Research output: Patent

2020

Accelerating Fourier Transform-Ion Cyclotron Resonance Mass Spectrometry Imaging Using a Subspace Approach

Xie, Y. R., Castro, D. C., Lam, F. & Sweedler, J. V., Nov 4 2020, In: Journal of the American Society for Mass Spectrometry. 31, 11, p. 2338-2347 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Biodegradable MRI Visible Drug Eluting Stent Reinforced by Metal Organic Frameworks

Hamideh, R. A., Akbari, B., Fathi, P., Misra, S. K., Sutrisno, A., Lam, F. & Pan, D., Jul 1 2020, In: Advanced Healthcare Materials. 9, 14, 2000136.

Research output: Contribution to journal › Article › peer-review

Open Access

Constrained Magnetic Resonance Spectroscopic Imaging by Learning Nonlinear Low-Dimensional Models

Lam, F., Li, Y. & Peng, X., Mar 2020, In: IEEE transactions on medical imaging. 39, 3, p. 545-555 11 p., 8770102.

Research output: Contribution to journal › Article › peer-review

Open Access

High-Resolution 3D Spin-Echo MRSI Using Interleaved Water Navigators, Sparse Sampling and Subspace-Based Processing

Ho, R. J. & Lam, F., Jul 2020, 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society: Enabling Innovative Technologies for Global Healthcare, EMBC 2020. Institute of Electrical and Electronics Engineers Inc., p. 1465-1468 4 p. 9176633. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; vol. 2020-July).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

High-Resolution Dynamic ³¹P-MR Spectroscopic Imaging for Mapping Mitochondrial Function

Clifford, B., Gu, Y., Liu, Y., Kim, K., Huang, S., Li, Y., Lam, F., Liang, Z. P. & Yu, X., Oct 2020, In: IEEE Transactions on Biomedical Engineering. 67, 10, p. 2745-2753 9 p., 8972401.

Research output: Contribution to journal › Article › peer-review

Open Access

Intravoxel B₀ inhomogeneity corrected reconstruction using a low-rank encoding operator

Lam, F. & Sutton, B. P., Aug 1 2020, In: Magnetic Resonance in Medicine. 84, 2, p. 885-894 10 p.

Research output: Contribution to journal › Article › peer-review

Separation of Metabolite and Macromolecule Signals for ¹ H-Mrsi Using Learned Nonlinear Models

Li, Y., Wang, Z. & Lam, F., Apr 2020, ISBI 2020 - 2020 IEEE International Symposium on Biomedical Imaging. IEEE Computer Society, p. 1725-1728 4 p. 9098365. (Proceedings - International Symposium on Biomedical Imaging; vol. 2020-April).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Ultrafast magnetic resonance spectroscopic imaging using SPICE with learned subspaces

Lam, F., Li, Y., Guo, R., Clifford, B. & Liang, Z. P., Feb 1 2020, In: Magnetic Resonance in Medicine. 83, 2, p. 377-390 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2019

System and method for high-resolution spectroscopic imaging

Lam, F. (Inventor), Ma, C. (Inventor) & Liang, Z.-P. (Inventor), Jul 2 2019, U.S. Patent No. 10338178, Jan 11 2016

Research output: Patent

2018

Early-life iron deficiency reduces brain iron content and alters brain tissue composition despite iron repletion: A neuroimaging assessment

Mudd, A. T., Fil, J. E., Knight, L. C., Lam, F., Liang, Z. P. & Dilger, R. N., Feb 2018, In: Nutrients. 10, 2, 135.

Research output: Contribution to journal › Article › peer-review

Open Access

Macromolecule mapping of the brain using ultrashort-TE acquisition and reference-based metabolite removal

Lam, F., Li, Y., Clifford, B. & Liang, Z.-P., May 2018, In: Magnetic Resonance in Medicine. 79, 5, p. 2460-2469 10 p.

Research output: Contribution to journal › Article › peer-review

Simultaneous QSM and metabolic imaging of the brain using SPICE

Peng, X., Lam, F., Li, Y., Clifford, B. & Liang, Z. P., Jan 2018, In: Magnetic Resonance in Medicine. 79, 1, p. 13-21 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2017

A subspace approach to spectral quantification for MR spectroscopic imaging

Li, Y., Lam, F., Clifford, B. & Liang, Z. P., Oct 2017, In: IEEE Transactions on Biomedical Engineering. 64, 10, p. 2486-2489 4 p., 8013142.

Research output: Contribution to journal › Article › peer-review

Open Access

High-resolution ¹H-MRSI of the brain using short-TE SPICE

Ma, C., Lam, F., Ning, Q., Johnson, C. L. & Liang, Z. P., Feb 1 2017, In: Magnetic Resonance in Medicine. 77, 2, p. 467-479 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

High-resolution dynamic ³¹P-MRSI using a low-rank tensor model

Ma, C., Clifford, B., Liu, Y., Gu, Y., Lam, F., Yu, X. & Liang, Z. P., Aug 2017, In: Magnetic Resonance in Medicine. 78, 2, p. 419-428 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Spectral Quantification for High-Resolution MR Spectroscopic Imaging with Spatiospectral Constraints

Ning, Q., Ma, C., Lam, F. & Liang, Z. P., May 2017, In: IEEE Transactions on Biomedical Engineering. 64, 5, p. 1178-1186 9 p., 7523255.

Research output: Contribution to journal › Article › peer-review

Open Access

2016

Accelerated High-Dimensional MR Imaging with Sparse Sampling Using Low-Rank Tensors

He, J., Liu, Q., Christodoulou, A. G., Ma, C., Lam, F. & Liang, Z. P., Sep 2016, In: IEEE transactions on medical imaging. 35, 9, p. 2119-2129 11 p., 7451247.

Research output: Contribution to journal › Article › peer-review

Open Access

A fast algorithm for denoising magnitude diffusion-weighted images with rank and edge constraints

Lam, F., Liu, D., Song, Z., Schuff, N. & Liang, Z. P., Jan 1 2016, In: Magnetic Resonance in Medicine. 75, 1, p. 433-440 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

High-resolution ¹H-MRSI of the brain using SPICE: Data acquisition and image reconstruction

Lam, F., Ma, C., Clifford, B., Johnson, C. L. & Liang, Z. P., Oct 1 2016, In: Magnetic Resonance in Medicine. 76, 4, p. 1059-1070 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Image Reconstruction Using Analysis Model Prior

Han, Y., Du, H., Lam, F., Mei, W. & Fang, L., 2016, In: Computational and Mathematical Methods in Medicine. 2016, 7571934.

Research output: Contribution to journal › Article › peer-review

Open Access

Improved low-rank filtering of magnetic resonance spectroscopic imaging data corrupted by noise and B₀ field inhomogeneity

Liu, Y., Ma, C., Clifford, B. A., Lam, F., Johnson, C. L. & Liang, Z. P., Apr 1 2016, In: IEEE Transactions on Biomedical Engineering. 63, 4, p. 841-849 9 p., 7239580.

Research output: Contribution to journal › Article › peer-review

Removal of nuisance signals from limited and sparse ¹H MRSI data using a union-of-subspaces model

Ma, C., Lam, F., Johnson, C. L. & Liang, Z. P., Feb 1 2016, In: Magnetic Resonance in Medicine. 75, 2, p. 488-497 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2015

Accelerated MR parameter mapping with low-rank and sparsity constraints

Zhao, B., Lu, W., Hitchens, T. K., Lam, F., Ho, C. & Liang, Z. P., Aug 1 2015, In: Magnetic Resonance in Medicine. 74, 2, p. 489-498 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Encoding and decoding with prior knowledge: From SLIM to SPICE

Ma, C., Lam, F. & Liang, Z.-P., 2015, In: eMagRes. 4, 2, p. 535-542 8 p.

Research output: Contribution to journal › Review article › peer-review

High temporal resolution functional MRI with partial separability model

Ngo, G. C., Holtrop, J. L., Fu, M., Lam, F. & Sutton, B. P., Nov 4 2015, 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Institute of Electrical and Electronics Engineers Inc., p. 7482-7485 4 p. 7320122. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; vol. 2015-November).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Joint estimation of spherical harmonic coefficients from magnitude diffusion-weighted images with sparsity constraints

Lam, F., Zhao, B. & Liang, Z.-P., Jul 21 2015, 2015 IEEE 12th International Symposium on Biomedical Imaging, ISBI 2015. IEEE Computer Society, p. 947-950 4 p. 7164027. (Proceedings - International Symposium on Biomedical Imaging; vol. 2015-July).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Maximum likelihood reconstruction for magnetic resonance fingerprinting

Zhao, B., Lam, F., Bilgic, B., Ye, H. & Setsompop, K., Jul 21 2015, 2015 IEEE 12th International Symposium on Biomedical Imaging, ISBI 2015. IEEE Computer Society, p. 905-909 5 p. 7164017. (Proceedings - International Symposium on Biomedical Imaging; vol. 2015-July).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

2014

A subspace approach to high-resolution spectroscopic imaging

Lam, F. & Liang, Z. P., Apr 2014, In: Magnetic Resonance in Medicine. 71, 4, p. 1349-1357 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Denoising diffusion-weighted magnitude MR images using rank and edge constraints

Lam, F., Babacan, S. D., Haldar, J. P., Weiner, M. W., Schuff, N. & Liang, Z. P., Mar 2014, In: Magnetic Resonance in Medicine. 71, 3, p. 1272-1284 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Field-inhomogeneity-corrected low-rank filtering of magnetic resonance spectroscopic imaging data

Liu, Y., Ma, C., Clifford, B., Lam, F., Johnson, C. L. & Liang, Z. P., Nov 2 2014, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014. Institute of Electrical and Electronics Engineers Inc., p. 6422-6425 4 p. 6945098. (2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Improved image reconstruction for subspace-based spectroscopic imaging using non-quadratic regularization

Wu, Z. H., Lam, F., Ma, C. & Liang, Z. P., Nov 2 2014, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014. Institute of Electrical and Electronics Engineers Inc., p. 2432-2435 4 p. 6944113. (2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Magnetic resonance image reconstruction from undersampled measurements using a patch-based nonlocal operator

Qu, X., Hou, Y., Lam, F., Guo, D., Zhong, J. & Chen, Z., Aug 2014, In: Medical Image Analysis. 18, 6, p. 843-856 14 p.

Research output: Contribution to journal › Article › peer-review

Model-based MR parameter mapping with sparsity constraints: Parameter estimation and performance bounds

Zhao, B., Lam, F. & Liang, Z. P., Sep 2014, In: IEEE transactions on medical imaging. 33, 9, p. 1832-1844 13 p., 6813689.

Research output: Contribution to journal › Article › peer-review

Open Access

2013

Magnetic resonance image reconstruction using similarities learnt from multi-modal images

Qu, X., Hou, Y., Lam, F., Guo, D. & Chen, Z., 2013, 2013 IEEE China Summit and International Conference on Signal and Information Processing, ChinaSIP 2013 - Proceedings. p. 264-268 5 p. 6625341. (2013 IEEE China Summit and International Conference on Signal and Information Processing, ChinaSIP 2013 - Proceedings).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Model-based MR parameter mapping with sparsity constraint

Zhao, B., Lam, F., Lu, W. & Liang, Z. P., 2013, ISBI 2013 - 2013 IEEE 10th International Symposium on Biomedical Imaging: From Nano to Macro. p. 1-4 4 p. 6556397. (Proceedings - International Symposium on Biomedical Imaging).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Fan Lam

Research output

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