Research Output per year
Research Output 2006 2019
2019
CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer
Racioppi, L., Nelson, E., Huang, W., Mukherjee, D., Lawrence, S. A., Lento, W., Masci, A. M., Jiao, Y., Park, S., York, B., Liu, Y., Baek, A. E., Drewry, D. H., Zuercher, W. J., Bertani, F. R., Businaro, L., Geradts, J., Hall, A., Means, A. R., Chao, N. & 2 others, , Dec 1 2019, In : Nature communications. 10, 1, 2450.Research output: Contribution to journal › Article
Open Access
T-cells
regulators
Myeloid Cells
breast
Tumors
Estrogen-independent Myc overexpression confers endocrine therapy resistance on breast cancer cells expressing ERαY537S and ERαD538G mutations
Yu, L., Wang, L., Mao, C., Duraki, D., Kim, J. E., Huang, R., Helferich, W. G., Nelson, E., Park, B. H. & Shapiro, D. J., Feb 1 2019, In : Cancer Letters. 442, p. 373-382 10 p.Research output: Contribution to journal › Article
Estrogen Receptors
Estrogens
Breast Neoplasms
Mutation
Neoplasm Metastasis
Host CYP27A1 expression is essential for ovarian cancer progression
He, S., Ma, L., Baek, A. E., Vardanyan, A., Vembar, V., Chen, J. J., Nelson, A. T., Burdette, J. E. & Nelson, E., Jan 1 2019, In : Endocrine-Related Cancer. 26, 7, p. 659-675 17 p.Research output: Contribution to journal › Article
Ovarian Neoplasms
Disease-Free Survival
Cholesterol
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Liver
Small Heterodimer Partner Regulates Dichotomous T Cell Expansion by Macrophages
Shahoei, S. H., Kim, Y. C., Cler, S. J., Ma, L., Anakk, S., Kemper, J. K. & Nelson, E. R., Jan 1 2019, In : Endocrinology. 160, 7, p. 1573-1589 17 p.Research output: Contribution to journal › Article
Macrophages
T-Lymphocytes
Down-Regulation
Interleukin-2
Adoptive Transfer
2018
Plasticizers used in food-contact materials affect adipogenesis in 3T3-L1 cells
Pomatto, V., Cottone, E., Cocci, P., Mozzicafreddo, M., Mosconi, G., Nelson, E. R., Palermo, F. A. & Bovolin, P., Apr 2018, In : Journal of Steroid Biochemistry and Molecular Biology. 178, p. 322-332 11 p.Research output: Contribution to journal › Article
3T3-L1 Cells
Plasticizers
Adipogenesis
Food
rosiglitazone
Targeting multidrug-resistant ovarian cancer through estrogen receptor a dependent ATP depletion caused by hyperactivation of the unfolded protein response
Zheng, X., Andruska, N., Lambrecht, M. J., He, S., Parissenti, A., Hergenrother, P., Nelson, E. & Shapiro, D. J., Jan 1 2018, In : Oncotarget. 9, 19, p. 14741-14753 13 p.Research output: Contribution to journal › Article
Unfolded Protein Response
Estrogen Receptors
Ovarian Neoplasms
Paclitaxel
Adenosine Triphosphate
Vertical Integration of Cell-Laden Hydrogels with Bioinspired Photonic Crystal Membranes
Pei, Y., Shahoei, S. H., Li, Y., Reece, P. J., Nelson, E. R., Gooding, J. J. & Kilian, K. A., Dec 7 2018, In : Advanced Materials Interfaces. 5, 23, 1801233.Research output: Contribution to journal › Article
Porous silicon
Photonic crystals
Hydrogels
Membranes
Biopolymers
2017
CYP27A1 loss dysregulates cholesterol homeostasis in prostate cancer
Alfaqih, M. A., Nelson, E. R., Liu, W., Safi, R., Jasper, J. S., Macias, E., Geradts, J., Thompson, J. W., Dubois, L. G., Freeman, M. R., Chang, C. Y., Chi, J. T., McDonnell, D. P. & Freedland, S. J., Jan 1 2017, In : Cancer Research. 77, 7, p. 1662-1673 12 p.Research output: Contribution to journal › Article
Prostatic Neoplasms
Homeostasis
Cholesterol
Sterol Regulatory Element Binding Protein 2
Down-Regulation
The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells
Baek, A. E., Yu, Y. R. A., He, S., Wardell, S. E., Chang, C. Y., Kwon, S., Pillai, R. V., McDowell, H. B., Thompson, J. W., Dubois, L. G., Sullivan, P. M., Kemper, K. J., Gunn, M. D., McDonnell, D. P. & Nelson, E., Dec 1 2017, In : Nature communications. 8, 1, 864.Research output: Contribution to journal › Article
neutrophils
metabolites
cholesterol
metastasis
Metabolites
2016
A protocol for the comprehensive flow cytometric analysis of immune cells in normal and inflamed murine non-lymphoid tissues
Yu, Y. R. A., O'Koren, E. G., Hotten, D. F., Kan, M. J., Kopin, D., Nelson, E. R., Que, L. & Gunn, M. D., Mar 2016, In : PloS one. 11, 3, e0150606.Research output: Contribution to journal › Article
Macrophages
Tissue
mice
dendritic cells
Tumors
Chemotherapy enriches for an invasive triple-negative breast tumor cell subpopulation expressing a precursor form of N-cadherin on the cell surface
Nelson, E. R., Li, S., Kennedy, M., Payne, S., Kilibarda, K., Groth, J., Bowie, M., Parilla-Castellar, E., de Ridder, G., Marcom, P. K., Lyes, M., Peterson, B. L., Cook, M., Pizzo, S. V., McDonnell, D. P. & Bachelder, R. E., Jan 1 2016, In : Oncotarget. 7, 51, p. 84030-84042 13 p.Research output: Contribution to journal › Article
Cadherins
Triple Negative Breast Neoplasms
Breast Neoplasms
Drug Therapy
Neoplasms
Efficient Targeting of Adipose Tissue Macrophages in Obesity with Polysaccharide Nanocarriers
Ma, L., Liu, T. W., Wallig, M. A., Dobrucki, I. T., Dobrucki, L. W., Nelson, E. R., Swanson, K. S. & Smith, A. M., Jul 26 2016, In : ACS Nano. 10, 7, p. 6952-6962 11 p.Research output: Contribution to journal › Article
obesity
adipose tissues
macrophages
Macrophages
polysaccharides
Thyroid hormone regulates vitellogenin by inducing estrogen receptor alpha in the goldfish liver
Nelson, E. & Habibi, H. R., Nov 15 2016, In : Molecular and Cellular Endocrinology. 436, p. 259-267 9 p.Research output: Contribution to journal › Article
Vitellogenins
Goldfish
Estrogen Receptor alpha
Thyroid Hormones
Liver
2015
Effect of aerobic training on the host systemic milieu in patients with solid tumours: An exploratory correlative study
Glass, O. K., Inman, B. A., Broadwater, G., Courneya, K. S., Mackey, J. R., Goruk, S., Nelson, E., Jasper, J., Field, C. J., Bain, J. R., Muehlbauer, M., Stevens, R. D., Hirschey, M. D. & Jones, L. W., Mar 3 2015, In : British Journal of Cancer. 112, 5, p. 825-831 7 p.Research output: Contribution to journal › Article
Angiogenesis Inducing Agents
Neoplasms
Cytokines
Macrophage Inflammatory Proteins
Ergometry
Evaluation of the pharmacological activities of RAD1901, a selective estrogen receptor degrader
Wardell, S. E., Nelson, E. R., Chao, C. A., Alley, H. M. & McDonnell, D. P., Oct 1 2015, In : Endocrine-Related Cancer. 22, 5, p. 713-724 12 p.Research output: Contribution to journal › Article
Estrogen Receptor alpha
Estrogen Receptors
Pharmacology
Breast Neoplasms
Selective Estrogen Receptor Modulators
2014
Copper signaling axis as a target for prostate cancer therapeutics
Safi, R., Nelson, E. R., Chitneni, S. K., Franz, K. J., George, D. J., Zalutsky, M. R. & McDonnell, D. P., Oct 15 2014, In : Cancer Research. 74, 20, p. 5819-5831 13 p.Research output: Contribution to journal › Article
Copper
Prostatic Neoplasms
Disulfiram
Androgen Receptors
Therapeutics
Delineation of a FOXA1/ERα/AGR2 regulatory loop that is dysregulated in endocrine therapy-resistant breast cancer
Wright, T. M., Wardell, S. E., Jasper, J. S., Stice, J. P., Safi, R., Nelson, E. R. & McDonnell, D. P., Dec 1 2014, In : Molecular Cancer Research. 12, 12, p. 1829-1839 11 p.Research output: Contribution to journal › Article
Estrogen Receptors
Breast Neoplasms
Tamoxifen
Selective Estrogen Receptor Modulators
Drug Resistance
From empirical to mechanism-based discovery of clinically useful Selective Estrogen Receptor Modulators (SERMs)
Wardell, S. E., Nelson, E. & McDonnell, D. P., Nov 15 2014, In : Steroids. 90, p. 30-38 9 p.Research output: Contribution to journal › Article
Selective Estrogen Receptor Modulators
Ligands
Estrogen Receptors
Estrogens
Pharmaceutical Preparations
The estrogen receptor as a mediator of the pathological actions of cholesterol in breast cancer
Mcdonnell, D. P., Chang, C. Y. & Nelson, E., Dec 1 2014, In : Climacteric. 17, p. 60-65 6 p.Research output: Contribution to journal › Article
Estrogen Receptors
Cholesterol
Breast Neoplasms
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Obesity
2013
27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology
Nelson, E., Wardell, S. E., Jasper, J. S., Park, S., Suchindran, S., Howe, M. K., Carver, N. J., Pillai, R. V., Sullivan, P. M., Sondhi, V., Umetani, M., Geradts, J. & McDonnell, D. P., Jan 1 2013, In : Science. 342, 6162, p. 1094-1098 5 p.Research output: Contribution to journal › Article
Hypercholesterolemia
Breast Neoplasms
Estrogen Receptors
Neoplasms
Cholesterol
Bazedoxifene exhibits antiestrogenic activity in animal models of tamoxifen-resistant breast cancer: Implications for treatment of advanced disease
Wardell, S. E., Nelson, E. R., Chao, C. A. & McDonnell, D. P., May 1 2013, In : Clinical Cancer Research. 19, 9, p. 2420-2431 12 p.Research output: Contribution to journal › Article
Tamoxifen
Animal Models
Selective Estrogen Receptor Modulators
Breast Neoplasms
Estrogen Receptors
2012
Exercise modulation of the host-tumor interaction in an orthotopic model of murine prostate cancer
Jones, L. W., Antonelli, J., Masko, E. M., Broadwater, G., Lascola, C. D., Fels, D., Dewhirst, M. W., Dyck, J. R. B., Nagendran, J., Flores, C. T., Betof, A. S., Nelson, E. R., Pollak, M., Dash, R. C., Young, M. E. & Freedland, S. J., Jul 15 2012, In : Journal of Applied Physiology. 113, 2, p. 263-272 10 p.Research output: Contribution to journal › Article
Prostatic Neoplasms
Neoplasms
Neoplasm Metastasis
Vascular Endothelial Growth Factor A
Mitogen-Activated Protein Kinase Kinases
The cytoskeletal regulatory scaffold protein GIT2 modulates mesenchymal stem cell differentiation and osteoblastogenesis
Wang, X., Liao, S., Nelson, E., Schmalzigaug, R., Spurney, R. F., Guilak, F., Premont, R. T. & Gesty-Palmer, D., Aug 24 2012, In : Biochemical and Biophysical Research Communications. 425, 2, p. 407-412 6 p.Research output: Contribution to journal › Article
Osteoclasts
Stem cells
Osteoblasts
Mesenchymal Stromal Cells
Scaffolds
2011
Auto-regulation of thyroid hormone receptors in the goldfish ovary and testis
Nelson, E., Allan, E. R. O., Pang, F. Y. & Habibi, H. R., May 15 2011, In : General and Comparative Endocrinology. 172, 1, p. 50-55 6 p.Research output: Contribution to journal › Article
autoregulation
Thyroid Hormone Receptors
Goldfish
goldfish
Testis
Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation
Michalek, R. D., Gerriets, V. A., Nichols, A. G., Inoue, M., Kazmin, D., Chang, C. Y., Dwyer, M. A., Nelson, E. R., Pollizzi, K. N., Ilkayeva, O., Giguere, V., Zuercher, W. J., Powell, J. D., Shinohara, M. L., McDonnell, D. P. & Rathmell, J. C., Nov 8 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 45, p. 18348-18353 6 p.Research output: Contribution to journal › Article
Eragrostis
Estrogen Receptors
Cell Differentiation
T-Lymphocytes
Glucose
The oxysterol, 27-hydroxycholesterol, links cholesterol metabolism to bone homeostasis through its actions on the estrogen and liver X receptors
Nelson, E. R., DuSell, C. D., Wang, X., Howe, M. K., Evans, G., Michalek, R. D., Umetani, M., Rathmell, J. C., Khosla, S., Gesty-Palmer, D. & McDonnell, D. P., Dec 1 2011, In : Endocrinology. 152, 12, p. 4691-4705 15 p.Research output: Contribution to journal › Article
Osteoporosis
Estrogens
Homeostasis
Osteoblasts
Cholesterol
2010
Functional significance of nuclear estrogen receptor subtypes in the liver of goldfish
Nelson, E. R. & Habibi, H. R., Apr 1 2010, In : Endocrinology. 151, 4, p. 1668-1676 9 p.Research output: Contribution to journal › Article
Goldfish
Estrogen Receptors
Liver
Estradiol
Fishes
Gender-related expression of TRα and TRβ in the protandrous black porgy, Acanthopagrus schlegeli, during sex change processes
An, K. W., An, M. I., Nelson, E., Habibi, H. R. & Choi, C. Y., Jan 1 2010, In : General and Comparative Endocrinology. 165, 1, p. 11-18 8 p.Research output: Contribution to journal › Article
porgy
Acanthopagrus schlegelii schlegelii
Thyroid Hormone Receptors
sex reversal
gender
Regulation of aryl hydrocarbon receptor function by selective estrogen receptor modulators
DuSell, C. D., Nelson, E., Wittmann, B. M., Fretz, J. A., Kazmin, D., Thomas, R. S., Pike, J. W. & McDonnell, D. P., Jan 1 2010, In : Molecular Endocrinology. 24, 1, p. 33-46 14 p.Research output: Contribution to journal › Article
Selective Estrogen Receptor Modulators
Aryl Hydrocarbon Receptors
Estrogen Receptors
Tamoxifen
Pharmacology
The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis
DuSell, C. D., Nelson, E., Wang, X., Abdo, J., Mödder, U. I., Umetani, M., Gesty-Palmer, D., Javitt, N. B., Khosla, S. & McDonnell, D. P., Aug 1 2010, In : Endocrinology. 151, 8, p. 3675-3685 11 p.Research output: Contribution to journal › Article
Selective Estrogen Receptor Modulators
Homeostasis
Bone and Bones
Estrogens
Cholesterol
Thyroid hormone and reproduction: Regulation of estrogen receptors in goldfish gonads
Nelson, E. R., Allan, E. R. O., Pang, F. Y. & Habibi, H. R., Sep 1 2010, In : Molecular reproduction and development. 77, 9, p. 784-794 11 p.Research output: Contribution to journal › Article
Goldfish
Gonads
Thyroid Hormones
Estrogen Receptors
Reproduction
2009
Seasonal regulation of vitellogenin by growth hormone in the goldfish liver
Moussavi, M., Nelson, E. & Habibi, H. R., Mar 2009, In : General and Comparative Endocrinology. 161, 1, p. 79-82 4 p.Research output: Contribution to journal › Article
Vitellogenins
Goldfish
goldfish
vitellogenin
somatotropin
Thyroid receptor subtypes: Structure and function in fish
Nelson, E. & Habibi, H. R., Mar 2009, In : General and Comparative Endocrinology. 161, 1, p. 90-96 7 p.Research output: Contribution to journal › Article
Thyroid Gland
Fishes
receptors
vertebrates
Vertebrates
2008
Basin-wide impacts of compounds with estrogen-like activity on longnose dace (Rhinichthys cataractae) in two prairie rivers of Alberta, Canada
Jeffries, K. M., Nelson, E. R., Jackson, L. J. & Habibi, H. R., Oct 1 2008, In : Environmental Toxicology and Chemistry. 27, 10, p. 2042-2052 11 p.Research output: Contribution to journal › Article
Cyprinidae
Alberta
Rivers
Vitellogenins
prairie
Characterization of estrogen receptor β2 and expression of the estrogen receptor subtypes α, β1, and β2 in the protandrous black porgy (Acanthopagrus schlegeli) during the sex change process
An, K. W., Nelson, E. R., Jo, P. G., Habibi, H. R., Shin, H. S. & Choi, C. Y., Jul 1 2008, In : Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology. 150, 3, p. 284-291 8 p.Research output: Contribution to journal › Article
Estrogen Receptor beta
Estrogen Receptor alpha
Estrogen Receptors
Gonads
Testis
Functional significance of a truncated thyroid receptor subtype lacking a hormone-binding domain in goldfish
Nelson, E. R. & Habibi, H. R., Sep 1 2008, In : Endocrinology. 149, 9, p. 4702-4709 8 p.Research output: Contribution to journal › Article
Goldfish
Thyroid Gland
Hormones
Iodide Peroxidase
Thyroid Hormones
Molecular characterization and expression of three GnRH forms mRNA during gonad sex-change process, and effect of GnRHa on GTH subunits mRNA in the protandrous black porgy (Acanthopagrus schlegeli)
An, K. W., Nelson, E., Habibi, H. R. & Choi, C. Y., Oct 2008, In : General and Comparative Endocrinology. 159, 1, p. 38-45 8 p.Research output: Contribution to journal › Article
porgy
Acanthopagrus schlegelii schlegelii
sex reversal
Gonads
gonadotropin-releasing hormone
Seasonal-related homologous regulation of goldfish liver Estrogen receptor subtypes
Nelson, E. & Habibi, H. R., Jul 31 2008, In : Cybium. 32, 2 SUPPL., p. 248-249 2 p.Research output: Contribution to journal › Article
goldfish
liver
estrogens
gonads
estrogen receptors
2007
Cadmium affects the expression of metallothionein (MT) and glutathione peroxidase (GPX) mRNA in goldfish, Carassius auratus
Choi, C. Y., An, K. W., Nelson, E. & Habibi, H. R., May 1 2007, In : Comparative Biochemistry and Physiology - C Toxicology and Pharmacology. 145, 4, p. 595-600 6 p.Research output: Contribution to journal › Article
Goldfish
Metallothionein
Glutathione Peroxidase
Cadmium
Cadmium Chloride
Homologous regulation of estrogen receptor subtypes in goldfish (Carassius auratus)
Nelson, E., Wiehler, W. B., Cole, W. C. & Habibi, H. R., Sep 1 2007, In : Molecular reproduction and development. 74, 9, p. 1105-1112 8 p.Research output: Contribution to journal › Article
Goldfish
Estrogen Receptors
Estradiol
Estrogens
Liver
2006
Molecular characterization and sex-related seasonal expression of thyroid receptor subtypes in goldfish
Nelson, E. & Habibi, H. R., Jul 11 2006, In : Molecular and Cellular Endocrinology. 253, 1-2, p. 83-95 13 p.Research output: Contribution to journal › Article
Goldfish
Thyroid Gland
Nucleotides
Amino Acids
Protein Isoforms