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Personal profile

Personal profile

Emad Tajkhorshid is Hastings Endowed Chair in the Biochemistry Department, as well as holds additional appointments across multiple colleges that include Chemistry, Bioengineering, Pharmacology, Biophysics and Quantitative Biology, Computational Science and Engineering, and the Carle-Illinois College of Medicine at the University of Illinois. He is also a full time faculty member of the Beckman Institute for Advanced Science and Technology. He joined the faculty of the Departments of Biochemistry (LAS) and Pharmacology (UI COM) in 2007 and was fast tracked to associate professor with tenure in 2010 and then again to the rank of professor in 2013. His tenure dossier was selected as one of the two top UIUC tenure cases on campus. In 2015, Professor Tajkhorshid was named a University of Illinois Scholar, after being nominated by both UIUC and UIC campuses. In 2016, he was awarded the Faculty Excellence Award from the School of Molecular and Cellular Biology at UIUC. Later that year he was named Endowed Chair in Biochemistry. Emad Tajkhorshid directs the leads the NIH Center for Macromolecular Modeling and Bioinformatics and the Computational Structural Biology and Molecular Biophysics Group at the Beckman Institute. Dr. Tajkhorshid has authored over 200 research articles (H-index 64) with over 23,000 citations in such high profile journals as Nature, Science, Cell, eLife, and PNAS. He has delivered nearly 200 invited lectures at international meetings, universities, and research institutes. He has served on the Editorial Boards of multiple major journals, including Biophysical Journal, Journal of Biological Chemistry, PLoS Computational Biology, and Biochemical and Biophysical Research Communication.

Professional Information

The Tajkhorshid Group focuses on developing and applying advanced computational techniques to characterization of biological phenomena, particularly membranes and membrane proteins, with the aim of achieving the most detailed microscopic view of structural and dynamical bases underlying biological function. Major areas of his extensive research portfolio, which have enjoyed continuous support from multiple federal funding agencies (NIH, NSF, DOE, DOD) over many years, include mechanistic studies of membrane transport proteins, principles of energy transduction and coupling in bioenergetic proteins, and lipid modulation of protein function, e.g., in signaling proteins associated with the cellular membrane.

Honors & Awards

NIH Transformative Award, 2017-2022
Endowed Chair of Biochemistry, 2016-
MCB Faculty Excellence Award, 2016
University of Illinois Scholar, 2015-2018
UIUC top tenure packages of the year, 2010

Office Address

3147 Beckman Institute, MC-251
405 N. Mathews Ave.
Urbana, IL 61801

Office Phone

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Research Output

Structure of the alternative complex III in a supercomplex with cytochrome oxidase

Sun, C., Benlekbir, S., Venkatakrishnan, P., Wang, Y., Hong, S., Hosler, J., Tajkhorshid, E., Rubinstein, J. L. & Gennis, R. B., May 3 2018, In : Nature. 557, 7703, p. 123-126 4 p.

Research output: Contribution to journalArticle

  • Probing key elements of teixobactin-lipid II interactions in membranes

    Wen, P. C., Vanegas, J. M., Rempe, S. B. & Tajkhorshid, E., Jan 1 2018, In : Chemical Science. 9, 34, p. 6997-7008 12 p.

    Research output: Contribution to journalArticle

  • Lipids and ions traverse the membrane by the same physical pathway in the nhTMEM16 scramblase

    Jiang, T., Yu, K., Hartzell, H. C. & Tajkhorshid, E., Sep 16 2017, In : eLife. 6, e28671.

    Research output: Contribution to journalArticle

  • Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM

    Chen, S., Zhao, Y., Wang, Y., Shekhar, M., Tajkhorshid, E. & Gouaux, E., Sep 7 2017, In : Cell. 170, 6, p. 1234-1246.e14

    Research output: Contribution to journalArticle

  • Energy transduction and alternating access of the mammalian ABC transporter P-glycoprotein

    Verhalen, B., Dastvan, R., Thangapandian, S., Peskova, Y., Koteiche, H. A., Nakamoto, R. K., Tajkhorshid, E. & McHaourab, H. S., Mar 30 2017, In : Nature. 543, 7647, p. 738-741 4 p.

    Research output: Contribution to journalArticle