Douglas Alan Mitchell

20052018
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Biological Products Medicine & Life Sciences
Thiazoles Medicine & Life Sciences
Oxazoles Medicine & Life Sciences
Biosynthesis Chemical Compounds
Peptides Medicine & Life Sciences
Anti-Bacterial Agents Medicine & Life Sciences
Multigene Family Medicine & Life Sciences
Nitrosation Medicine & Life Sciences

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Research Output 2005 2018

Bioinformatic Expansion and Discovery of Thiopeptide Antibiotics

Schwalen, C. J., Hudson, G. A., Kille, B. & Mitchell, D. A., Aug 1 2018, In : Journal of the American Chemical Society. 140, 30, p. 9494-9501 8 p.

Research output: Contribution to journalArticle

Thioamides
bioinformatics
Antibiotics
Bioinformatics
Multigene Family

Elucidation of the roles of conserved residues in the biosynthesis of the lasso peptide paeninodin

Hegemann, J. D., Schwalen, C. J., Mitchell, D. A. & van der Donk, W. A., Jan 1 2018, In : Chemical Communications. 54, 65, p. 9007-9010 4 p.

Research output: Contribution to journalArticle

Biosynthesis
Peptides
Assays
Proteolysis
Substrates

Enzymatic reconstitution of ribosomal peptide backbone thioamidation

Mahanta, N., Liu, A., Dong, S., Nair, S. K. & Mitchell, D. A., Mar 20 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 12, p. 3030-3035 6 p.

Research output: Contribution to journalArticle

Oxidoreductases
Peptides
Archaea
Post Translational Protein Processing
Proteins

RiPP antibiotics: biosynthesis and engineering potential

Hudson, G. A. & Mitchell, D. A., Oct 1 2018, In : Current Opinion in Microbiology. 45, p. 61-69 9 p.

Research output: Contribution to journalReview article

Anti-Bacterial Agents
Biosynthetic Pathways
Biological Products
Peptide Synthases
Synthetic Biology

A new genome-mining tool redefines the lasso peptide biosynthetic landscape

Tietz, J. I., Schwalen, C. J., Patel, P. S., Maxson, T., Blair, P. M., Tai, H. C., Zakai, U. I. & Mitchell, D. A., May 1 2017, In : Nature chemical biology. 13, 5, p. 470-478 9 p.

Research output: Contribution to journalArticle

Genome
Peptides
Citrulline
Data Mining
Multigene Family