Douglas Alan Mitchell

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Biological Products Medicine & Life Sciences
Thiazoles Medicine & Life Sciences
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Biosynthesis Chemical Compounds
Peptides Medicine & Life Sciences
Anti-Bacterial Agents Medicine & Life Sciences
Multigene Family Medicine & Life Sciences
Nitrosation Medicine & Life Sciences

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Research Output 2005 2018

Bioinformatic Expansion and Discovery of Thiopeptide Antibiotics

Schwalen, C. J., Hudson, G. A., Kille, B. & Mitchell, D. A., Aug 1 2018, In : Journal of the American Chemical Society. 140, 30, p. 9494-9501 8 p.

Research output: Contribution to journalArticle

Multigene Family

Elucidation of the roles of conserved residues in the biosynthesis of the lasso peptide paeninodin

Hegemann, J. D., Schwalen, C. J., Mitchell, D. A. & van der Donk, W. A., Jan 1 2018, In : Chemical Communications. 54, 65, p. 9007-9010 4 p.

Research output: Contribution to journalArticle


Enzymatic reconstitution of ribosomal peptide backbone thioamidation

Mahanta, N., Liu, A., Dong, S., Nair, S. K. & Mitchell, D. A., Mar 20 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 12, p. 3030-3035 6 p.

Research output: Contribution to journalArticle

Post Translational Protein Processing

RiPP antibiotics: biosynthesis and engineering potential

Hudson, G. A. & Mitchell, D. A., Oct 1 2018, In : Current Opinion in Microbiology. 45, p. 61-69 9 p.

Research output: Contribution to journalReview article

Anti-Bacterial Agents
Biosynthetic Pathways
Biological Products
Peptide Synthases
Synthetic Biology

A new genome-mining tool redefines the lasso peptide biosynthetic landscape

Tietz, J. I., Schwalen, C. J., Patel, P. S., Maxson, T., Blair, P. M., Tai, H. C., Zakai, U. I. & Mitchell, D. A., May 1 2017, In : Nature chemical biology. 13, 5, p. 470-478 9 p.

Research output: Contribution to journalArticle

Data Mining
Multigene Family