Douglas Alan Mitchell

20052018
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Nitrosation Medicine & Life Sciences

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Research Output 2005 2018

Enzymatic reconstitution of ribosomal peptide backbone thioamidation

Mahanta, N., Liu, A., Dong, S., Nair, S. K. & Mitchell, D. A. Mar 20 2018 In : Proceedings of the National Academy of Sciences of the United States of America. 115, 12, p. 3030-3035 6 p.

Research output: Contribution to journalArticle

Oxidoreductases
Peptides
Mutagenesis
Proteins
Nucleotides

RiPP antibiotics: biosynthesis and engineering potential

Hudson, G. A. & Mitchell, D. A. Oct 1 2018 In : Current Opinion in Microbiology. 45, p. 61-69 9 p.

Research output: Contribution to journalReview article

Anti-Bacterial Agents
Biosynthetic Pathways
Biological Products
Peptide Synthases
Synthetic Biology

A new genome-mining tool redefines the lasso peptide biosynthetic landscape

Tietz, J. I., Schwalen, C. J., Patel, P. S., Maxson, T., Blair, P. M., Tai, H. C., Zakai, U. I. & Mitchell, D. A. May 1 2017 In : Nature Chemical Biology. 13, 5, p. 470-478 9 p.

Research output: Contribution to journalArticle

Genome
Peptides
Citrulline
Data Mining
Multigene Family

AntiSMASH 4.0 - improvements in chemistry prediction and gene cluster boundary identification

Blin, K., Wolf, T., Chevrette, M. G., Lu, X., Schwalen, C. J., Kautsar, S. A., Suarez Duran, H. G., De Los Santos, E. L. C., Kim, H. U., Nave, M., Dickschat, J. S., Mitchell, D. A., Shelest, E., Breitling, R., Takano, E., Lee, S. Y., Weber, T. & Medema, M. H. Jul 3 2017 In : Nucleic acids research. 45, W1, p. W36-W41

Research output: Contribution to journalArticle

Multigene Family
Food Preservatives
Peptide Synthases
Genome
Polyketide Synthases

Chimeric Leader Peptides for the Generation of Non-Natural Hybrid RiPP Products

Burkhart, B. J., Kakkar, N., Hudson, G. A., Van Der Donk, W. A. & Mitchell, D. A. Jun 28 2017 In : ACS Central Science. 3, 6, p. 629-638 10 p.

Research output: Contribution to journalArticle

Protein Sorting Signals
Enzymes
Peptides
Biosynthesis
Substrates