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Research Output 1987 2019

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PNIPAM chain collapse depends on the molecular weight and grafting density

Plunkett, K. N., Zhu, X., Moore, J. S. & Leckband, D. E., Apr 25 2006, In : Langmuir. 22, 9, p. 4259-4266 8 p.

Research output: Contribution to journalArticle

molecular weight
Molecular weight
initiators
Polymers
polymers

Poly(N-isopropyl acrylamide) brush topography: Dependence on grafting conditions and temperature

Choi, B. C., Choi, S. & Leckband, D. E., May 14 2013, In : Langmuir. 29, 19, p. 5841-5850 10 p.

Research output: Contribution to journalArticle

brushes
Brushes
Topography
topography
Ellipsometry

Polypyrrole nanospheres with magnetic and cell-targeting capabilities

Wuang, S. C., Neoh, K. G., Kang, E. T., Pack, D. W. & Leckband, D. E., Apr 2 2007, In : Macromolecular Rapid Communications. 28, 7, p. 816-821 6 p.

Research output: Contribution to journalArticle

Nanospheres
Polypyrroles
Hyaluronic acid
Hyaluronic Acid
Surface-Active Agents

Protein adsorption mechanisms determine the efficiency of thermally controlled cell adhesion on poly(N -isopropyl acrylamide) brushes

Choi, S., Choi, B. C., Xue, C. & Leckband, D. E., Jan 14 2013, In : Biomacromolecules. 14, 1, p. 92-100 9 p.

Research output: Contribution to journalArticle

Cell adhesion
Brushes
Proteins
Adsorption
Polymers

Protein adsorption modes determine reversible cell attachment on poly(N-isopropyl acrylamide) brushes

Xue, C., Choi, B. C., Choi, S., Braun, P. V. & Leckband, D. E., Jun 6 2012, In : Advanced Functional Materials. 22, 11, p. 2394-2401 8 p.

Research output: Contribution to journalArticle

brushes
Brushes
attachment
proteins
Proteins

Protein adsorption on poly(N -isopropylacrylamide) brushes: Dependence on grafting density and chain collapse

Xue, C., Yonet-Tanyeri, N., Brouette, N., Sferrazza, M., Braun, P. V. & Leckband, D. E., Jul 19 2011, In : Langmuir. 27, 14, p. 8810-8818 9 p.

Research output: Contribution to journalArticle

brushes
Brushes
proteins
Proteins
Adsorption

Protein adsorption properties of OEG monolayers and dense PNIPAM brushes probed by neutron reflectivity

Brouette, N., Xue, C., Haertlein, M., Moulin, M., Fragneto, G., Leckband, D. E., Halperin, A. & Sferrazza, M., Dec 1 2012, In : European Physical Journal: Special Topics. 213, 1, p. 343-353 11 p.

Research output: Contribution to journalArticle

brushes
Brushes
Monolayers
Neutrons
proteins

Protein-induced changes in poly(ethylene glycol) brushes: Molecular weight and temperature dependence

Efremova, N. V., Sheth, S. R. & Leckband, D. E., Nov 27 2001, In : Langmuir. 17, 24, p. 7628-7636 9 p.

Research output: Contribution to journalArticle

brushes
Brushes
Polyethylene glycols
glycols
molecular weight

Recapitulating cell-cell adhesion using N-cadherin biologically tethered to substrates

Vega L., J. C. M., Lee, M. K., Jeong, J. H., Smith, C. E., Lee, K. Y., Chung, H. J., Leckband, D. E. & Kong, H., Jun 9 2014, In : Biomacromolecules. 15, 6, p. 2172-2179 8 p.

Research output: Contribution to journalArticle

Cell adhesion
Cadherins
Substrates
Adhesion
Gels

Regiospecific control of protein expression in cells cultured on two-component counter gradients of extracellular matrix proteins

Gunawan, R. C., Choban, E. R., Conour, J. E., Silvestre, J., Schook, L. B., Gaskins, H. R., Leckband, D. E. & Kenis, P. J. A., Mar 29 2005, In : Langmuir. 21, 7, p. 3061-3068 8 p.

Research output: Contribution to journalArticle

Extracellular Matrix Proteins
cultured cells
counters
Cytology
Immobilized Proteins

Role of Calcium in the Adhesion and Fusion of Bilayers

Leckband, D. E., Helm, C. A. & Israelachvili, J., Jan 1 1993, In : Biochemistry. 32, 4, p. 1127-1140 14 p.

Research output: Contribution to journalArticle

Fusion reactions
Adhesion
Calcium
Choline
Static Electricity

Salt bridges gate ?-catenin activation at intercellular junctions

Barrick, S., Li, J., Kong, X., Ray, A., Tajkhorshid, E. & Leckband, D., Jan 15 2018, In : Molecular biology of the cell. 29, 2, p. 111-122 12 p.

Research output: Contribution to journalArticle

Catenins
Intercellular Junctions
Salts
Vinculin
Cadherins

Similarities between heterophilic and homophilic cadherin adhesion

Prakasam, A. K., Maruthamuthu, V. & Leckband, D. E., Oct 17 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 42, p. 15434-15439 6 p.

Research output: Contribution to journalArticle

Cadherins
Cell Separation
Proteins
Xenopus
Morphogenesis

Simulations of the adhesion between molecularly bonded surfaces in direct force measurements

Vijayendran, R., Hammer, D. & Leckband, D. E., May 8 1998, In : Journal of Chemical Physics. 108, 18, p. 7783-7794 12 p.

Research output: Contribution to journalArticle

Force measurement
adhesion
Adhesion
simulation
Biological materials

Single cell 3-D platform to study ligand mobility in cell-cell contact

Andreasson-Ochsner, M., Romano, G., Håkanson, M., Smith, M. L., Leckband, D. E., Textor, M. & Reimhult, E., Sep 7 2011, In : Lab on a Chip. 11, 17, p. 2876-2883 8 p.

Research output: Contribution to journalArticle

Cadherins
Lipid bilayers
Cell adhesion
Ligands
Cell membranes
Neural Cell Adhesion Molecules
Adhesion
Molecules
Rupture
Nerve Tissue

Single-molecule measurements of the impact of lipid phase behavior on anchor strengths

Wieland, J. A., Gewirth, A. A. & Leckband, D. E., Mar 31 2005, In : Journal of Physical Chemistry B. 109, 12, p. 5985-5993 9 p.

Research output: Contribution to journalArticle

Phase behavior
Anchors
Lipids
lipids
Molecules

Soluble Zwitterionic Poly(sulfobetaine) Destabilizes Proteins

Kisley, L., Serrano, K. A., Davis, C. M., Guin, D., Murphy, E. A., Gruebele, M. H. W. & Leckband, D. E., Sep 10 2018, In : Biomacromolecules. 19, 9, p. 3894-3901 8 p.

Research output: Contribution to journalArticle

Proteins
Polymers
Polyethylene glycols
Protein folding
Tryptophan

Structural and functional optical imaging of three-dimensional engineered tissue development

Tan, W., Sendemir-Urkmez, A., Fahrner, L. J., Jamison, R., Leckband, D. & Boppart, S. A., Jan 1 2004, In : Tissue Engineering. 10, 11-12, p. 1747-1756 10 p.

Research output: Contribution to journalArticle

Tissue
Imaging techniques
Optical tomography
Confocal microscopy
Structural dynamics

Structural determinants of the mechanical stability of α-Catenin

Li, J., Newhall, J., Ishiyama, N., Gottardi, C., Ikura, M., Leckband, D. E. & Tajkhorshid, E., Jul 31 2015, In : Journal of Biological Chemistry. 290, 31, p. 18890-18903 14 p.

Research output: Contribution to journalArticle

Catenins
Mechanical stability
Cell adhesion
Molecular Dynamics Simulation
Cell Adhesion

Structural studies of the neural-cell-adhesion molecule by X-ray and neutron reflectivity

Johnson, C. P., Fragneto, G., Konovalov, O., Dubosclard, V., Legrand, J. F. & Leckband, D. E., Jan 18 2005, In : Biochemistry. 44, 2, p. 546-554 9 p.

Research output: Contribution to journalArticle

Neural Cell Adhesion Molecules
Neutrons
X-Rays
X rays
Ionic strength

Structure and Dynamics of Ion-Induced Domains in Free and Supported Monolayers and Bilayers

Evert, L. L., Leckband, D. E. & Israelachvili, J. N., Jan 1 1994, In : Langmuir. 10, 1, p. 303-315 13 p.

Research output: Contribution to journalArticle

Monolayers
Ions
ions
Calcium
Ostwald ripening

Substrate stiffness and VE-cadherin mechano-transduction coordinate to regulate endothelial monolayer integrity

Andresen Eguiluz, R. C., Kaylan, K. B., Underhill, G. H. & Leckband, D. E., Sep 2017, In : Biomaterials. 140, p. 45-57 13 p.

Research output: Contribution to journalArticle

Signal transduction
Rigidity
Monolayers
Stiffness
Signal Transduction

Synthesis and characterization of an electroactive surface that releases γ-aminobutyric acid (GABA)

Yan, C., Matsuda, W., Pepperberg, D. R., Zimmerman, S. C. & Leckband, D. E., Apr 1 2006, In : Journal of Colloid And Interface Science. 296, 1, p. 165-177 13 p.

Research output: Contribution to journalArticle

Aminobutyrates
quinones
gamma-Aminobutyric Acid
Self assembled monolayers
acids

Synthesis and functionalization of polypyrrole-Fe3O4 nanoparticles for applications in biomedicine

Wuang, S. C., Neoh, K. G., Kang, E. T., Pack, D. W. & Leckband, D. E., Jul 31 2007, In : Journal of Materials Chemistry. 17, 31, p. 3354-3362 9 p.

Research output: Contribution to journalArticle

Polypyrroles
Nanoparticles
Cells
Folic Acid
Polyvinyl Alcohol

The influence of protein and interfacial structure on the self-assembly of oriented protein arrays

Leckband, D. E., Jan 1 1997, In : Advances in Biophysics. 34, p. 173-190 18 p.

Research output: Contribution to journalArticle

Protein Array Analysis
Self assembly
Membrane Proteins
Adsorption
Proteins

The surface force apparatus - A tool for probing molecular protein interactions

Leckband, D. E., Aug 17 1995, In : Nature. 376, 6541, p. 617-618 2 p.

Research output: Contribution to journalArticle

Molecular Probes
Membrane Fluidity
Surface Properties
Static Electricity
Membranes

Three dimensional conjugation of recombinant N-cadherin to a hydrogel for: In vitro anisotropic neural growth

Vega, J. C. M. L., Lee, M. K., Qin, E. C., Rich, M., Lee, K. Y., Kim, D. H., Chung, H. J., Leckband, D. E. & Kong, H., Jan 1 2016, In : Journal of Materials Chemistry B. 4, 42, p. 6803-6811 9 p.

Research output: Contribution to journalArticle

Hydrogel
Cadherins
Hydrogels
Gels
Neurons

Tissue organization by cadherin adhesion molecules: Dynamic Molecular and Cellular Mechanisms of Morphogenetic Regulation

Niessen, C. M., Leckband, D. & Yap, A. S., Apr 1 2011, In : Physiological Reviews. 91, 2, p. 691-731 41 p.

Research output: Contribution to journalArticle

Cell Physiological Phenomena
Cell Surface Receptors
Cadherins
Molecular Dynamics Simulation
Cytoskeleton

Transport effects on the kinetics of protein-surface binding

Balgi, G., Leckband, D. E. & Nitsche, J. M., Jan 1 1995, In : Biophysical journal. 68, 6, p. 2251-2260 10 p.

Research output: Contribution to journalArticle

Avidin
Protein Binding
Biotin
Static Electricity

Tuning the Interfacial Properties of Grafted Chains with a pH Switch

Zhu, X., DeGraaf, J., Winnik, F. M. & Leckband, D., Feb 17 2004, In : Langmuir. 20, 4, p. 1459-1465 7 p.

Research output: Contribution to journalArticle

Polymer films
Glycine
Amino acids
Polymers
switches

Two-dimensional protein crystallization at solid-liquid interfaces

Calvert, T. L. & Leckband, D., Dec 10 1997, In : Langmuir. 13, 25, p. 6737-6745 9 p.

Research output: Contribution to journalArticle

liquid-solid interfaces
Crystallization
Lipids
lipids
crystallization

Two stage cadherin kinetics require multiple extracellular domains but not the cytoplasmic region

Chien, Y. H., Jiang, N., Li, F., Zhang, F., Zhu, C. & Leckband, D. E., Jan 25 2008, In : Journal of Biological Chemistry. 283, 4, p. 1848-1856 9 p.

Research output: Contribution to journalArticle

Cadherins
Kinetics
Xenopus
Adhesion
Binding Sites

Variably elastic hydrogel patterned via capillary action in microchannels

Dong, R., Jensen, T. W., Engberg, K., Nuzzo, R. G. & Leckband, D. E., Jan 30 2007, In : Langmuir. 23, 3, p. 1483-1488 6 p.

Research output: Contribution to journalArticle

Hydrogels
Hydrogel
microchannels
Microchannels
Gels

VE-PTP stabilizes VE-cadherin junctions and the endothelial barrier via a phosphatase-independent mechanism

Juettner, V. V., Kruse, K., Dan, A., Vu, V. H., Khan, Y., Le, J., Leckband, D., Komarova, Y. & Malik, A. B., May 1 2019, In : Journal of Cell Biology. 218, 5, p. 1725-1742 18 p.

Research output: Contribution to journalArticle

Open Access
Class 3 Receptor-Like Protein Tyrosine Phosphatases
Phosphoric Monoester Hydrolases
Adherens Junctions
Blood Vessels
Rho Guanine Nucleotide Exchange Factors

Vinculin-dependent Cadherin mechanosensing regulates efficient epithelial barrier formation

Twiss, F., Le Duc, Q., Van Der Horst, S., Tabdili, H., Van Der Krogt, G., Wang, N., Rehmann, H., Huveneers, S., Leckband, D. E. & De Rooij, J., Nov 15 2012, In : Biology Open. 1, 11, p. 1128-1140 13 p.

Research output: Contribution to journalArticle

Vinculin
cadherins
Cadherins
Actomyosin
Cell adhesion

Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II-dependent manner

Le Duc, Q., Shi, Q., Blonk, I., Sonnenberg, A., Wang, N., Leckband, D. & De Rooij, J., Jun 28 2010, In : Journal of Cell Biology. 189, 7, p. 1107-1115 9 p.

Research output: Contribution to journalArticle

Myosin Type II
Vinculin
Adherens Junctions
Cadherins
Actins

X-ray reflectivity investigations of two-dimensional assemblies of C-cadherins: First steps in structural and functional studies

Martel, L., Johnson, C., Boutet, S., Al-Kurdi, R., Konovalov, O., Robinson, I., Leckband, D. E. & Legrand, J. F., Jul 1 2002, In : Journal De Physique. IV : JP. 12, 6

Research output: Contribution to journalArticle

Cadherins
assemblies
proteins
Proteins
reflectance

α-Catenin cytomechanics - role in cadherin-dependent adhesion and mechanotransduction

Barry, A. K., Tabdili, H., Muhamed, I., Wu, J., Shashikanth, N., Gomez, G. A., Yap, A. S., Gottardi, C. J., De Rooij, J., Wang, N. & Leckband, D. E., 2014, In : Journal of cell science. 127, 8, p. 1779-1791 13 p.

Research output: Contribution to journalArticle

Catenins
Cadherins
Actins
Vinculin
Traction

α-Catenin phosphorylation promotes intercellular adhesion through a dual-kinase mechanism

Escobar, D. J., Desai, R., Ishiyama, N., Folmsbee, S. S., Novak, M. N., Flozak, A. S., Daugherty, R. L., Mo, R., Nanavati, D., Sarpal, R., Leckband, D., Ikura, M., Tepass, U. & Gottardi, C. J., Jan 1 2015, In : Journal of cell science. 128, 6, p. 1150-1165 16 p.

Research output: Contribution to journalArticle

Catenins
Phosphotransferases
Phosphorylation
Cadherins
Drosophila