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Research Output 1987 2019

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2001

Protein-induced changes in poly(ethylene glycol) brushes: Molecular weight and temperature dependence

Efremova, N. V., Sheth, S. R. & Leckband, D. E., Nov 27 2001, In : Langmuir. 17, 24, p. 7628-7636 9 p.

Research output: Contribution to journalArticle

brushes
Brushes
Polyethylene glycols
glycols
molecular weight
2000

Effect of the microenvironment on the recognition of immobilized cytochromes by soluble redox proteins

Kloss, A. A., Lavrik, N., Yeung, C. & Leckband, D. E., Apr 4 2000, In : Langmuir. 16, 7, p. 3414-3421 8 p.

Research output: Contribution to journalArticle

Streptavidin
cytochromes
Cytochromes
Monolayers
proteins

Force probe measurements of antibody-antigen interactions

Leckband, D. E., Kuhl, T. L., Wang, H. K., Müller, W., Herron, J. & Ringsdorf, H., Jan 1 2000, In : Methods. 20, 3, p. 329-340 12 p.

Research output: Contribution to journalArticle

Antigens
Antibodies
Fluorescein
Antibody Binding Sites
Immunoglobulin Fab Fragments
ship hulls
contact lenses
proteins
adsorption
monomers

Interactions of poly(ethylene oxide) brushes with chemically selective surfaces

Sheth, S. R., Efremova, N. & Leckband, D. E., Aug 17 2000, In : Journal of Physical Chemistry B. 104, 32, p. 7652-7662 11 p.

Research output: Contribution to journalArticle

Ethylene Oxide
selective surfaces
brushes
Brushes
ethylene oxide

Long-term maintenance of patterns of hippocampal pyramidal cells on substrates of polyethylene glycol and micro stamped poly lysine

Branch, D. W., Wheeler, B. C., Brewer, G. J. & Leckband, D. E., Dec 1 2000, In : IEEE Transactions on Biomedical Engineering. 47, 3, p. 290-300 11 p.

Research output: Contribution to journalArticle

Polyethylene glycols
Neurons
Substrates
Molecules
Amino acids

Measurements of interbilayer forces and protein adsorption on uncharged lipid bilayers displaying poly(ethylene glycol) chains

Efremova, N. V., Bondurant, B., O'Brien, D. F. & Leckband, D. E., Mar 28 2000, In : Biochemistry. 39, 12, p. 3441-3451 11 p.

Research output: Contribution to journalArticle

Lipid bilayers
Ethylene Glycol
Lipid Bilayers
Liposomes
Polyethylene glycols

Optical and direct force measurements of the interactions between monolayers of aromatic macrocycles on surfactant monolayers

Lavrik, N. & Leckband, D. E., Feb 22 2000, In : Langmuir. 16, 4, p. 1842-1851 10 p.

Research output: Contribution to journalArticle

Force measurement
Surface-Active Agents
Monolayers
Surface active agents
Coloring Agents
1999

A computational reaction-diffusion model for the analysis of transport- limited kinetics

Vijayendran, R. A., Ligler, F. S. & Leckband, D. E., Dec 1 1999, In : Analytical chemistry. 71, 23, p. 5405-5412 8 p.

Research output: Contribution to journalArticle

Biosensors
Kinetics
Trinitrotoluene
Trinitrobenzenes
Antibodies

Cytochrome c recognition of immobilized, orientational variants of cytochrome b5: Direct force and equilibrium binding measurements

Yeung, C., Purves, T., Kloss, A. A., Kuhl, T. L., Sligar, S. & Leckband, D. E., Sep 28 1999, In : Langmuir. 15, 20, p. 6829-6836 8 p.

Research output: Contribution to journalArticle

Cytochromes b5
cytochromes
Cytochromes c
Force measurement
Proteins

Direct molecular force measurements of multiple adhesive interactions between cadherin ectodomains

Sivasankar, S., Brieher, W., Lavrik, N., Gumbiner, B. & Leckband, D., Oct 12 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 21, p. 11820-11824 5 p.

Research output: Contribution to journalArticle

Cadherins
Adhesives
Proteins
Xenopus
Rupture

Forces controlling protein interactions: Theory and experiment

Leckband, D. E. & Sivasankar, S., Aug 1999, In : Colloids and Surfaces B: Biointerfaces. 14, 1-4, p. 83-97 15 p.

Research output: Contribution to journalArticle

proteins
Proteins
Experiments
interactions
Computational methods

Grafted poly(ethylene oxide) brushes as nonfouling surface coatings

Leckband, D. E., Sheth, S. & Halperin, A., Jan 1 1999, In : Journal of Biomaterials Science, Polymer Edition. 10, 10, p. 1125-1147 23 p.

Research output: Contribution to journalArticle

Ethylene Oxide
Brushes
Polyethylene oxides
Adsorption
Membrane Proteins
1998

A neutron reflectivity study of polymer-modified phospholipid monolayers at the solid-solution interface: Polyethylene glycol-lipids on silane- modified substrates

Kuhl, T. L., Majewski, J., Wong, J. Y., Steinberg, S., Leckband, D. E., Israelachvili, J. N. & Smith, G. S., Nov 1998, In : Biophysical journal. 75, 5, p. 2352-2362 11 p.

Research output: Contribution to journalArticle

Silanes
Neutrons
Phospholipids
Polymers
Lipids

Cold and hot denaturation of polysoaps

Leckband, D. E., Borisov, O. V. & Halperin, A., Apr 7 1998, In : Macromolecules. 31, 7, p. 2368-2374 7 p.

Research output: Contribution to journalArticle

Denaturation
Polymers
Proteins
Amphiphiles
Water

Direct molecular level measurements of the electrostatic properties of a protein surface

Sivasankar, S., Subramaniam, S. & Leckband, D., Oct 27 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 22, p. 12961-12966 6 p.

Research output: Contribution to journalArticle

Static Electricity
Membrane Proteins
Streptavidin
Proteins

Molecular forces between membranes displaying neutral glycosphingolipids: Evidence for carbohydrate attraction

Yu, Z. W., Calvert, T. L. & Leckband, D. E., Feb 10 1998, In : Biochemistry. 37, 6, p. 1540-1550 11 p.

Research output: Contribution to journalArticle

Neutral Glycosphingolipids
Lactosylceramides
Carbohydrates
Glycolipids
Membranes

Simulations of the adhesion between molecularly bonded surfaces in direct force measurements

Vijayendran, R., Hammer, D. & Leckband, D. E., May 8 1998, In : Journal of Chemical Physics. 108, 18, p. 7783-7794 12 p.

Research output: Contribution to journalArticle

Force measurement
adhesion
Adhesion
simulation
Biological materials
1997

Direct force measurements of polymerization-dependent changes in the properties of diacetylene films

Sheth, S. R. & Leckband, D. E., Oct 15 1997, In : Langmuir. 13, 21, p. 5652-5662 11 p.

Research output: Contribution to journalArticle

Force measurement
polymerization
Polymerization
Contact angle
Polymers
Composition effects
Van der Waals forces
Force measurement
Polyethylene glycols
Proteins
Ethylene Glycol
Polymers
Streptavidin
Proteins
Protein Denaturation

Molecular level characterization of microenvironmental influences on the properties of immobilized proteins

Yeung, C. & Leckband, D., Dec 10 1997, In : Langmuir. 13, 25, p. 6746-6754 9 p.

Research output: Contribution to journalArticle

Immobilized Proteins
proteins
Proteins
Electrostatics
Cytochromes b5

The influence of protein and interfacial structure on the self-assembly of oriented protein arrays

Leckband, D. E., Jan 1 1997, In : Advances in Biophysics. 34, p. 173-190 18 p.

Research output: Contribution to journalArticle

Protein Array Analysis
Self assembly
Membrane Proteins
Adsorption
Proteins

Two-dimensional protein crystallization at solid-liquid interfaces

Calvert, T. L. & Leckband, D., Dec 10 1997, In : Langmuir. 13, 25, p. 6737-6745 9 p.

Research output: Contribution to journalArticle

liquid-solid interfaces
Crystallization
Lipids
lipids
crystallization
1996

Direct measurement of polyethylene glycol induced depletion attraction between lipid bilayers

Kuhl, T., Guo, Y., Alderfer, J. L., Berman, A. D., Leckband, D. E., Israelachvili, J. & Hui, S. W., Jun 12 1996, In : Langmuir. 12, 12, p. 3003-3014 12 p.

Research output: Contribution to journalArticle

Lipid bilayers
Polyethylene glycols
attraction
lipids
glycols
1995

4-4-20 Anti-Fluorescyl IgG Fab’ Recognition of Membrane Bound Hapten: Direct Evidence for the Role of Protein and Interfacial Structure

Leckband, D. E., Kuhl, T., Wang, H. K., Herron, J., Muller, W. & Ringsdorf, H., Sep 1995, In : Biochemistry. 34, 36, p. 11467-11478 12 p.

Research output: Contribution to journalArticle

Haptens
Static Electricity
Fluorescein
Membranes
Membrane Proteins

Heparinase I from Flavobacterium heparinum: The Role of the Cysteine Residue in Catalysis as Probed by Chemical Modification and Site-Directed Mutagenesis

Sasisekharan, R., Leckband, D. E., Godavarti, R., Venkataraman, G., Cooney, C. L. & Langer, R., Nov 1995, In : Biochemistry. 34, 44, p. 14441-14448 8 p.

Research output: Contribution to journalArticle

Heparin Lyase
Flavobacterium
Mutagenesis
Chemical modification
Site-Directed Mutagenesis

Molecular mechanisms determining the strength of receptor-mediated intermembrane adhesion

Leckband, D. E., Müller, W., Schmitt, F. J. & Ringsdorf, H., Jan 1 1995, In : Biophysical journal. 69, 3, p. 1162-1169 8 p.

Research output: Contribution to journalArticle

Membranes
Adhesives
Streptavidin
Tensile Strength
Ligands

The surface force apparatus - A tool for probing molecular protein interactions

Leckband, D. E., Aug 17 1995, In : Nature. 376, 6541, p. 617-618 2 p.

Research output: Contribution to journalArticle

Molecular Probes
Membrane Fluidity
Surface Properties
Static Electricity
Membranes

Transport effects on the kinetics of protein-surface binding

Balgi, G., Leckband, D. E. & Nitsche, J. M., Jan 1 1995, In : Biophysical journal. 68, 6, p. 2251-2260 10 p.

Research output: Contribution to journalArticle

Avidin
Protein Binding
Biotin
Static Electricity
1994

Direct Force Measurements of Specific and Nonspecific Protein Interactions

Leckband, D. E., Schmitt, F. J., Israelachvili, J. N. & Knoll, W., Apr 1 1994, In : Biochemistry. 33, 15, p. 4611-4624 14 p.

Research output: Contribution to journalArticle

Streptavidin
Force measurement
Biotin
Ligands
Temperature

Higher order self-assembly of vesicles by site-specific binding

Chiruvolu, S., Walker, S., Israelachvili, J., Schmitt, F. J., Leckband, D. E. & Zasadzinski, J. A., Jan 1 1994, In : Science. 264, 5166, p. 1753-1756 4 p.

Research output: Contribution to journalArticle

Cryoelectron Microscopy
Streptavidin
Biocompatible Materials
Binding Sites
Ligands

Modulation of interaction forces between bilayers exposing short-chained ethylene oxide headgroups

Kuhl, T. L., Leckband, D. E., Lasic, D. D. & Israelachvili, J. N., Jan 1 1994, In : Biophysical journal. 66, 5, p. 1479-1488 10 p.

Research output: Contribution to journalArticle

Ethylene Oxide
Lipids
Liposomes
Polymers
Mononuclear Phagocyte System

Structure and Dynamics of Ion-Induced Domains in Free and Supported Monolayers and Bilayers

Evert, L. L., Leckband, D. E. & Israelachvili, J. N., Jan 1 1994, In : Langmuir. 10, 1, p. 303-315 13 p.

Research output: Contribution to journalArticle

Monolayers
Ions
ions
Calcium
Ostwald ripening
1993

Measurements of conformational changes during adhesion of lipid and protein (polylysine and S‐layer) surfaces

Leckband, D., Chen, YL. L., Israelachvili, J., Wickman, H. H., Fletcher, M. & Zimmerman, R., Jun 20 1993, In : Biotechnology and bioengineering. 42, 2, p. 167-177 11 p.

Research output: Contribution to journalArticle

Polylysine
Lipids
Adhesion
Humidity
Proteins

Role of Calcium in the Adhesion and Fusion of Bilayers

Leckband, D. E., Helm, C. A. & Israelachvili, J., Jan 1 1993, In : Biochemistry. 32, 4, p. 1127-1140 14 p.

Research output: Contribution to journalArticle

Fusion reactions
Adhesion
Calcium
Choline
Static Electricity
1992

Long-range attraction and molecular rearrangements in receptor-ligand interactions

Leckband, D. E., Israelachvili, J. N., Schmitt, F. J. & Knoll, W., Jan 1 1992, In : Science. 255, 5050, p. 1419-1421 3 p.

Research output: Contribution to journalArticle

Ligands
Transition Temperature
Membranes
Proteins
1991

An approach for the stable immobilization of proteins

Leckband, D. & Langer, R., Feb 5 1991, In : Biotechnology and bioengineering. 37, 3, p. 227-237 11 p.

Research output: Contribution to journalArticle

Immobilization
Heparin Lyase
Proteins
Sepharose
Immobilized Proteins
1988

Function of Tightly Bound Nucleotides on Membrane-Bound Chloroplast Coupling Factor

Leckband, D. E. & Hammes, G. G., May 1 1988, In : Biochemistry. 27, 10, p. 3629-3633 5 p.

Research output: Contribution to journalArticle

Chloroplast Proton-Translocating ATPases
Nucleotides
Adenosine Triphosphate
Membranes
Adenosine Diphosphate
1987

Interactions between Nucleotide Binding Sites on Chloroplast Coupling Factor 1 during ATP Hydrolysis

Leckband, D. E. & Hammes, G. G., Jan 1 1987, In : Biochemistry. 26, 8, p. 2306-2312 7 p.

Research output: Contribution to journalArticle

Chloroplast Proton-Translocating ATPases
Hydrolysis
Nucleotides
Adenosine Triphosphate
Binding Sites