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Selection of functional T cell receptor mutants from a yeast surface-display library

Kieke, M. C., Shusta, E. V., Boder, E. T., Teyton, L., Wittrup, K. D. & Kranz, D. M., May 11 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 10, p. 5651-5656 6 p.

Research output: Contribution to journalArticle

Selection of variable-joining region combinations in the α chain of the T cell receptor

Roth, M. E., Lacy, M. J., Mcneil, L. K. & Kranz, D. M., Jan 1 1988, In : Science. 241, 4871, p. 1354-1358 5 p.

Research output: Contribution to journalArticle

Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice

Sha, W. C., Nelson, C. A., Newberry, R. D., Kranzt, D. M., Russell, J. H. & Loh, D. Y., Jan 1 1988, In : Nature. 335, 6187, p. 271-274 4 p.

Research output: Contribution to journalArticle

Sequence diversity of T cell receptor α chain transcripts from BALB/c thymus

Roth, M. E., Tjoa, B. A., Schlueter, C. J., Wilson, E. R., Lunn, B. C. & David, D. M., Dec 1992, In : Molecular Immunology. 29, 12, p. 1447-1455 9 p.

Research output: Contribution to journalArticle

Sequence restrictions in T cell receptor β-chains that have specificity for a self-peptide/Ld complex

Tjoa, B. A. & Kranz, D. M., Jul 1994, In : Molecular Immunology. 31, 10, p. 705-711 7 p.

Research output: Contribution to journalArticle

Single-chain Fv/folate conjugates mediate efficient lysis of folate-receptor-positive tumor cells

Cho, B. K., Roy, E. J., Patrick, T. A. & Kranz, D. M., May 1 1997, In : Bioconjugate Chemistry. 8, 3, p. 338-346 9 p.

Research output: Contribution to journalArticle

Single-chain VαVβ T-cell receptors function without mispairing with endogenous TCR chains

Aggen, D. H., Chervin, A. S., Schmitt, T. M., Engels, B., Stone, J. D., Richman, S. A., Piepenbrink, K. H., Baker, B. M., Greenberg, P. D., Schreiber, H. & Kranz, D. M., Apr 1 2012, In : Gene therapy. 19, 4, p. 365-374 10 p.

Research output: Contribution to journalArticle

Solution mapping of T cell receptor docking footprints on peptide-MHC

Varani, L., Bankovich, A. J., Liu, C. W., Colf, L. A., Jones, L. L., Kranz, D. M., Puglisi, J. D. & Garcia, K. C., Aug 7 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 32, p. 13080-13085 6 p.

Research output: Contribution to journalArticle

Specificity and binding properties of a single-chain T cell receptor

Schlueter, C. J., Schodin, B. A., Tetin, S. Y. & Kranz, D. M., Mar 15 1996, In : Journal of Molecular Biology. 256, 5, p. 859-869 11 p.

Research output: Contribution to journalArticle

Staphylococcal superantigens cause lethal pulmonary disease in rabbits

Strandberg, K. L., Rotschafer, J. H., Vetter, S. M., Buonpane, R. A., Kranz, D. M. & Schlievert, P. M., Dec 1 2010, In : Journal of Infectious Diseases. 202, 11, p. 1690-1697 8 p.

Research output: Contribution to journalArticle

Staphylococcal toxic shock syndrome erythroderma is associated with superantigenicity and hypersensitivity

John, C. C., Niermann, M., Sharon, B., Peterson, M. L., Kranz, D. M. & Schlievert, P. M., Dec 1 2009, In : Clinical Infectious Diseases. 49, 12, p. 1893-1896 4 p.

Research output: Contribution to journalArticle

Staphylococcus aureus isolates encode variant staphylococcal enterotoxin B proteins that are diverse in superantigenicity and lethality

Kohler, P. L., Greenwood, S. D., Nookala, S., Kotb, M., Kranz, D. M. & Schlievert, P. M., Jul 16 2012, In : PloS one. 7, 7, e41157.

Research output: Contribution to journalArticle

Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction

Cho, S., Swaminathan, C. P., Yang, J., Kerzic, M. C., Guan, R., Kieke, M. C., Kranz, D. M., Mariuzza, R. A. & Sundberg, E. J., Dec 1 2005, In : Structure. 13, 12, p. 1775-1787 13 p.

Research output: Contribution to journalArticle

Structural basis of T-cell specificity and activation by the bacterial superantigen TSST-1

Moza, B., Varma, A. K., Buonpane, R. A., Zhu, P., Herfst, C. A., Nicholson, M. J., Wilbuer, A. K., Seth, N. P., Wucherpfennig, K. W., McCormick, J. K., Kranz, D. M. & Sundberg, E. J., Feb 21 2007, In : EMBO Journal. 26, 4, p. 1187-1197 11 p.

Research output: Contribution to journalArticle

Structural features of T cell receptor variable regions that enhance domain stability and enable expression as single-chain VαVβ fragments

Richman, S. A., Aggen, D. H., Dossett, M. L., Donermeyer, D. L., Allen, P. M., Greenberg, P. D. & Kranz, D. M., Feb 1 2009, In : Molecular Immunology. 46, 5, p. 902-916 15 p.

Research output: Contribution to journalArticle

Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity

Adams, J. J., Narayanan, S., Birnbaum, M. E., Sidhu, S. S., Blevins, S. J., Gee, M. H., Sibener, L. V., Baker, B. M., Kranz, D. M. & Garcia, K. C., Jan 1 2016, In : Nature Immunology. 17, 1, p. 87-94 8 p.

Research output: Contribution to journalArticle

Structure, organization, and somatic rearrangement of T cell gamma genes

Hayday, A. C., Saito, H., Gillies, S. D., Kranz, D. M., Tanigawa, G., Eisen, H. N. & Tonegawa, S., Feb 1985, In : Cell. 40, 2, p. 259-269 11 p.

Research output: Contribution to journalArticle

Structure-guided engineering of the affinity and specificity of CARs against Tn-glycopeptides

Sharma, P., Marada, V. V. V. R., Cai, Q., Kizerwetter, M., He, Y., Wolf, S. P., Schreiber, K., Clausen, H., Schreiber, H. & Kranz, D. M., Jun 15 2020, (Accepted/In press) In : Proceedings of the National Academy of Sciences. 201920662.

Research output: Contribution to journalArticle

Studies of the TLR4-associated protein MD-2 using yeast-display and mutational analyses

Mattis, D. M., Chervin, A. S., Ranoa, D. R., Kelley, S. L., Tapping, R. I. & Kranz, D. M., May 8 2015, In : Molecular Immunology. 68, 2, p. 203-212 10 p.

Research output: Contribution to journalArticle

Subtle changes at the variable domain interface of the T-cell receptor can strongly increase affinity

Sharma, P. & Kranz, D. M., Feb 2 2018, In : Journal of Biological Chemistry. 293, 5, p. 1820-1834 15 p.

Research output: Contribution to journalArticle

Subtle changes in TCRα CDR1 profoundly increase the sensitivity of CD4 T cells

Lynch, J. N., Donermeyer, D. L., Weber, K. S., Kranz, D. M. & Allen, P. M., Mar 1 2013, In : Molecular Immunology. 53, 3, p. 283-294 12 p.

Research output: Contribution to journalArticle

Targeting T cells against brain tumors with a bispecific ligand-antibody conjugate

Roy, E. J., Cho, B. K., Rund, L. A., Patrick, T. A. & Kranz, D. M., Jun 10 1998, In : International Journal of Cancer. 76, 5, p. 761-766 6 p.

Research output: Contribution to journalArticle

Targeting tumor cells with bispecific antibodies and T cells

Kranz, D. M., Manning, T. C., Rund, L. A., Cho, B. K., Gruber, M. M. & Roy, E. J., Apr 30 1998, In : Journal of Controlled Release. 53, 1-3, p. 77-84 8 p.

Research output: Contribution to journalArticle

Targeting virus entry and membrane fusion through specific peptide/MHC complexes using a high-affinity T-cell receptor

Peng, K. W., Holler, P. D., Orr, B. A., Kranz, D. M. & Russell, S. J., Aug 1 2004, In : Gene therapy. 11, 15, p. 1234-1239 6 p.

Research output: Contribution to journalArticle

T cell receptor engineering and analysis using the yeast display platform

Smith, S. N., Harris, D. T. & Kranz, D. M., Jan 1 2015, In : Methods in Molecular Biology. 1319, p. 95-141 47 p.

Research output: Contribution to journalArticle

T Cell receptor rearrangements in various S49 lymphoma sublines

Johnson, N. A., Keeney, J. B., Hedayat, M., Clary, K. W., Kranz, D. M. & Hansen, T. H., Nov 1992, In : Molecular Immunology. 29, 11, p. 1325-1335 11 p.

Research output: Contribution to journalArticle

T cell receptors: Affinities, cross-reactivities, and a conformer model

Holler, P. D. & Kranz, D. M., Feb 2004, In : Molecular Immunology. 40, 14-15, p. 1027-1031 5 p.

Research output: Contribution to journalArticle

T-cell receptors engineered de novo for peptide specificity can mediate optimal t-cell activity without self cross-reactivity

Sharma, P., Harris, D. T., Stone, J. D. & Kranz, D. M., Jan 1 2019, In : Cancer Immunology Research. 7, 12, p. 2025-2035 11 p.

Research output: Contribution to journalArticle

T cell receptors for gene transfer in adoptive T cell therapy

Sharma, P. & Kranz, D. M., Jan 1 2019, In : Critical Reviews in Immunology. 39, 2, p. 105-122 18 p.

Research output: Contribution to journalArticle

T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex

Adams, J. J., Narayanan, S., Liu, B., Birnbaum, M. E., Kruse, A. C., Bowerman, N. A., Chen, W., Levin, A. M., Connolly, J. M., Zhu, C., Kranz, D. M. & Garcia, K. C., Nov 23 2011, In : Immunity. 35, 5, p. 681-693 13 p.

Research output: Contribution to journalArticle

T-cell receptor δ-chain diversity in peripheral lymphocytes

Lacy, M. J., McNeil, L. K., Roth, M. E. & Kranz, D. M., Jan 1 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 3, p. 1023-1026 4 p.

Research output: Contribution to journalArticle

TCR scanning of peptide/MHC through complementary matching of receptor and ligand molecular flexibility

Hawse, W. F., De, S., Greenwood, A. I., Nicholson, L. K., Zajicek, J., Kovrigin, E. L., Kranz, D. M., Garcia, K. C. & Baker, B. M., Mar 15 2014, In : Journal of Immunology. 192, 6, p. 2885-2891 7 p.

Research output: Contribution to journalArticle

Tertiary and quaternary structure of the T cell receptor α β chain dimer

Novotny, J., Tonegawa, S. & Kranz, D. M., Jan 1 1985, In : Federation Proceedings. 44, 6, p. No. 8841

Research output: Contribution to journalArticle

The cationic region from HIV tat enhances the cell-surface expression of epitope/MHC class I complexes

Leifert, J. A., Holler, P. D., Harkins, S., Kranz, D. M. & Whitton, J. L., Dec 1 2003, In : Gene therapy. 10, 25, p. 2067-2073 7 p.

Research output: Contribution to journalArticle

The central role of the antigen-specific receptor complex in triggering cytolytic activity of cytotoxic T lymphocytes

Eisen, H. N., Liu, M. A. & Kranz, D. M., Oct 1 1985, In : Bioscience Reports. 5, 10-11, p. 885-892 8 p.

Research output: Contribution to journalArticle

The Effect of Polymyxin B On Outer Membrane of Serratia Marcescens: Activation and Dissociation of Outer Membrane Associated Alkaline Phosphatase

Kranz, D. M., Brown, D. A. & Tsang, J. C., Jan 1 1977, In : Journal of Antibiotics. 30, 3, p. 270-271 2 p.

Research output: Contribution to journalArticle

The impact of TCR-binding properties and antigen presentation format on T cell responsiveness

Chervin, A. S., Stone, J. D., Holler, P. D., Bai, A., Chen, J., Eisen, H. N. & Kranz, D. M., Jul 15 2009, In : Journal of Immunology. 183, 2, p. 1166-1178 13 p.

Research output: Contribution to journalArticle

Thermodynamic Properties of Ligand Binding by Monoclonal Anti-fluorescyl Antibodies

Herron, J. N., Kranz, D. M., Jameson, D. M. & Voss, E. W., Aug 1986, In : Biochemistry. 25, 16, p. 4602-4609 8 p.

Research output: Contribution to journalArticle

The study of high-affinity TCRs reveals duality in T cell recognition of antigen: Specificity and degeneracy

Ponermeyer, D. L., Weber, K. S., Kranz, D. M. & Allen, P. M., Nov 15 2006, In : Journal of Immunology. 177, 10, p. 6911-6919 9 p.

Research output: Contribution to journalArticle

Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2Kb

Dam, J., Guan, R., Natarajan, K., Dimasi, N., Chlewicki, L. K., Kranz, D. M., Schuck, P., Margulies, D. H. & Mariuzza, R. A., Dec 1 2003, In : Nature Immunology. 4, 12, p. 1213-1222 10 p.

Research output: Contribution to journalArticle

Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency

Shusta, E. V., Kieke, M. C., Parke, E., Kranz, D. M. & Wittrup, K. D., Oct 8 1999, In : Journal of Molecular Biology. 292, 5, p. 949-956 8 p.

Research output: Contribution to journalArticle