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Research Output

Structure-guided engineering of the affinity and specificity of CARs against Tn-glycopeptides

Sharma, P., Marada, V. V. V. R., Cai, Q., Kizerwetter, M., He, Y., Wolf, S. P., Schreiber, K., Clausen, H., Schreiber, H. & Kranz, D. M., Jun 30 2020, In : Proceedings of the National Academy of Sciences. 117, 26, p. 15148-15159 12 p., 201920662.

Research output: Contribution to journalArticle

  • Breaking tolerance with engineered class I antigen-presenting molecules

    Parks, C. A., Henning, K. R., Pavelko, K. D., Hansen, M. J., Van Keulen, V. P., Reed, B. K., Stone, J. D., Schrum, A. G., Gil, D., Kranz, D. M., Bordner, A. J., Barry, M. A. & Pease, L. R., Feb 19 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 8, p. 3136-3145 10 p.

    Research output: Contribution to journalArticle

  • High-throughput stability screening of neoantigen/HLA complexes improves immunogenicity predictions

    Blaha, D. T., Anderson, S. D., Yoakum, D. M., Hager, M. V., Zha, Y., Gajewski, T. F. & Kranz, D. M., Jan 2019, In : Cancer Immunology Research. 7, 1, p. 50-61 12 p.

    Research output: Contribution to journalArticle

  • Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell

    He, Y., Schreiber, K., Wolf, S. P., Wen, F., Steentoft, C., Zerweck, J., Steiner, M., Sharma, P., Michael Shepard, H., Posey, A., June, C. H., Mandel, U., Clausen, H., Leisegang, M., Meredith, S. C., Kranz, D. M. & Schreiber, H., Oct 17 2019, In : JCI Insight. 4, 21, e130416.

    Research output: Contribution to journalArticle

    Open Access
  • T-cell receptors engineered de novo for peptide specificity can mediate optimal t-cell activity without self cross-reactivity

    Sharma, P., Harris, D. T., Stone, J. D. & Kranz, D. M., Jan 1 2019, In : Cancer Immunology Research. 7, 12, p. 2025-2035 11 p.

    Research output: Contribution to journalArticle