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Research Output

2019

Longitudinal bioluminescent imaging of HIV-1 infection during antiretroviral therapy and treatment interruption in humanized mice

Ventura, J. D., Beloor, J., Allen, E., Zhang, T., Haugh, K. A., Uchil, P. D., Ochsenbauer, C., Kieffer, C., Kumar, P., Hope, T. J. & Mothes, W., Jan 1 2019, In : PLoS pathogens. 15, 12, e1008161.

Research output: Contribution to journalArticle

Open Access

Mechanisms of virus dissemination in bone marrow of HIV-1–infected humanized BLT mice

Ladinsky, M. S., Khamaikawin, W., Jung, Y., Lin, S., Lam, J., An, D. S., Bjorkman, P. J. & Kieffer, C., Oct 2019, In : eLife. 8, e46916.

Research output: Contribution to journalArticle

Open Access
2017

Longitudinal imaging of hiv-1 spread in humanized mice with parallel 3D immunofluorescence and electron tomography

Kieffer, C., Ladinsky, M. S., Ninh, A., Galimidi, R. P. & Bjorkman, P. J., Feb 15 2017, In : eLife. 6, e23282.

Research output: Contribution to journalArticle

Multiscale Imaging of HIV-1 Transmission in Humanized Mice

Kieffer, C., Ladinsky, M. S. & Bjorkman, P. J., Nov 2017, In : AIDS Research and Human Retroviruses. 33, S1, p. S6-S7

Research output: Contribution to journalComment/debate

2015

Dioxin exposure blocks lactation through a direct effect on mammary epithelial cells mediated by the aryl hydrocarbon receptor repressor

Basham, K. J., Leonard, C. J., Kieffer, C., Shelton, D. N., McDowell, M. E., Bhonde, V. R., Looper, R. E. & Welm, B. E., Jan 1 2015, In : Toxicological sciences : an official journal of the Society of Toxicology. 143, 1, p. 36-45 10 p.

Research output: Contribution to journalArticle

2014

Bis-aryloxadiazoles as effective activators of the aryl hydrocarbon receptor

Basham, K. J., Bhonde, V. R., Kieffer, C., Mack, J. B. C., Hess, M., Welm, B. E. & Looper, R. E., Jun 1 2014, In : Bioorganic and Medicinal Chemistry Letters. 24, 11, p. 2473-2476 4 p.

Research output: Contribution to journalArticle

Electron Tomography of HIV-1 Infection in Gut-Associated Lymphoid Tissue

Ladinsky, M. S., Kieffer, C., Olson, G., Deruaz, M., Vrbanac, V., Tager, A. M., Kwon, D. S. & Bjorkman, P. J., Jan 1 2014, In : PLoS pathogens. 10, 1, e1003899.

Research output: Contribution to journalArticle

2013

Chemical genetic screen reveals a role for desmosomal adhesion in mammary branching morphogenesis

Basham, K. J., Kieffer, C., Shelton, D. N., Leonard, C. J., Bhonde, V. R., Vankayalapati, H., Milash, B., Bearss, D. J., Looper, R. E. & Welm, B. E., Jan 25 2013, In : Journal of Biological Chemistry. 288, 4, p. 2261-2270 10 p.

Research output: Contribution to journalArticle

2012

Targeting the PyMT Oncogene to Diverse Mammary Cell Populations Enhances Tumor Heterogeneity and Generates Rare Breast Cancer Subtypes

Smith, B. A., Shelton, D. N., Kieffer, C., Milash, B., Usary, J., Perou, C. M., Bernard, P. S. & Welm, B. E., Dec 1 2012, In : Genes and Cancer. 3, 9-10, p. 550-563 14 p.

Research output: Contribution to journalArticle

2008

Biochemical and Structural Studies of Yeast Vps4 Oligomerization

Gonciarz, M. D., Whitby, F. G., Eckert, D. M., Kieffer, C., Heroux, A., Sundquist, W. I. & Hill, C. P., Dec 26 2008, In : Journal of Molecular Biology. 384, 4, p. 878-895 18 p.

Research output: Contribution to journalArticle

Two Distinct Modes of ESCRT-III Recognition Are Required for VPS4 Functions in Lysosomal Protein Targeting and HIV-1 Budding

Kieffer, C., Skalicky, J. J., Morita, E., De Domenico, I., Ward, D. M., Kaplan, J. & Sundquist, W. I., Jul 8 2008, In : Developmental cell. 15, 1, p. 62-73 12 p.

Research output: Contribution to journalArticle

2007

Electron cryotomography of immature HIV-1 virions reveals the structure of the CA and SP1 Gag shells

Wright, E. R., Schooler, J. B., Ding, H. J., Kieffer, C., Fillmore, C., Sundquist, W. I. & Jensen, G. J., Apr 18 2007, In : EMBO Journal. 26, 8, p. 2218-2226 9 p.

Research output: Contribution to journalArticle

ESCRT-III recognition by VPS4 ATPases

Stuchell-Brereton, M. D., Skalicky, J. J., Kieffer, C., Karren, M. A., Ghaffarian, S. & Sundquist, W. I., Oct 11 2007, In : Nature. 449, 7163, p. 740-744 5 p.

Research output: Contribution to journalArticle