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Research Output 1996 2019

Article

Absence of estrogen receptor alpha leads to physiological alterations in the mouse epididymis and consequent defects in sperm function

Joseph, A., Hess, R. A., Schaeffer, D. J., Ko, C., Hudgin-Spivey, S., Chambon, P. & Shur, B. D., May 1 2010, In : Biology of reproduction. 82, 5, p. 948-957 10 p.

Research output: Contribution to journalArticle

Estrogen Receptor alpha
Epididymis
Spermatozoa
Proteins
Spermatogenesis

A low-copy-number plasmid for retrieval of toxic genes from BACs and generation of conditional targeting constructs

Na, G., Wolfe, A., Ko, C., Youn, H., Lee, Y. M., Byun, S. J., Jeon, I. & Koo, Y., Jun 1 2013, In : Molecular Biotechnology. 54, 2, p. 504-514 11 p.

Research output: Contribution to journalArticle

Poisons
Bacterial Artificial Chromosomes
Plasmids
Genes
Chromosomes

Androgen receptor in the ovary theca cells plays a critical role in androgen-induced reproductive dysfunction

Ma, Y., Andrisse, S., Chen, Y., Childress, S., Xue, P., Wang, Z., Jones, D., Ko, C., Divall, S. & Wu, S., Jan 1 2017, In : Endocrinology. 158, 1, p. 98-108 11 p.

Research output: Contribution to journalArticle

Theca Cells
Dihydrotestosterone
Androgen Receptors
Androgens
Ovary

Beclin-1 deficiency in the murine ovary results in the reduction of progesterone production to promote preterm labor

Gawriluk, T. R., Ko, C., Hong, X., Christenson, L. K. & Rucker, E. B., Sep 22 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 40, p. E4194-E4203

Research output: Contribution to journalArticle

Premature Obstetric Labor
Autophagy
Progesterone
Ovary
Reproduction

Birth of clones of the world's first cloned dog

Kim, M. J., Oh, H. J., Kim, G. A., Setyawan, E. M. N., Choi, Y. B., Lee, S. H., Petersen-Jones, S. M., Ko, C. M. J. & Lee, B. C., Dec 1 2017, In : Scientific reports. 7, 1, 15235.

Research output: Contribution to journalArticle

Clone Cells
Parturition
Dogs
Mesenchymal Stromal Cells
Organism Cloning

Conditional deletion of Bmal1 in ovarian theca cells disrupts ovulation in female mice

Mereness, A. L., Murphy, Z. C., Forrestel, A. C., Butler, S., Ko, C., Richards, J. A. S. & Sellix, M. T., Feb 2016, In : Endocrinology. 157, 2, p. 913-927 15 p.

Research output: Contribution to journalArticle

Theca Cells
Ovulation
Granulosa Cells
Fertility
LH Receptors

Core binding factor b expression in ovarian granulosa cells is essential for female fertility

Lee-Thacker, S., Choi, Y., Taniuchi, I., Takarada, T., Yoneda, Y., Ko, C. M. & Jo, M., May 1 2018, In : Endocrinology. 159, 5, p. 2094-2109 16 p.

Research output: Contribution to journalArticle

Core Binding Factors
Granulosa Cells
Fertility
Corpus Luteum
Ovary

Decay-accelerating factor in the periovulatory rat ovary

Gieske, M. C., Na, G. Y., Koo, Y., Jo, M., Curry, T. E. & Ko, C., Aug 1 2005, In : Journal of Endocrinology. 186, 2, p. 303-313 11 p.

Research output: Contribution to journalArticle

CD55 Antigens
Ovary
Glycosylphosphatidylinositols
Theca Cells
Chorionic Gonadotropin

Development and application of a rat ovarian gene expression database

Jo, M., Gieske, M. C., Payne, C. E., Wheeler-Price, S. E., Gieske, J. B., Ignatius, I. V., Curry, T. E. & Ko, C., Nov 1 2004, In : Endocrinology. 145, 11, p. 5384-5396 13 p.

Research output: Contribution to journalArticle

Databases
Gene Expression
Equine Gonadotropins
Genes
Transcriptome

Disrupted kisspeptin signaling in GnRH neurons leads to hypogonadotrophic hypogonadism

Novaira, H. J., Sonko, M. L., Hoffman, G., Koo, Y., Ko, C., Wolfe, A. & Radovick, S., Feb 1 2014, In : Molecular Endocrinology. 28, 2, p. 225-238 14 p.

Research output: Contribution to journalArticle

Kisspeptins
Hypogonadism
Gonadotropin-Releasing Hormone
Neurons
Periodicity

Dual suppression of estrogenic and inflammatory activities for targeting of endometriosis

Zhao, Y., Gong, P., Chen, Y., Nwachukwu, J. C., Srinivasan, S., Ko, C., Bagchi, M. K., Taylor, R. N., Korach, K. S., Nettles, K. W., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Jan 21 2015, In : Science Translational Medicine. 7, 271, 271ra9.

Research output: Contribution to journalArticle

Endometriosis
Estrogen Receptors
Estrogens
Fertility
Ligands

Endothelin-2 induces oviductal contraction via endothelin receptor subtype A in rats

Al-Alem, L., Bridges, P. J., Su, W., Gong, M. C., Iglarz, M. & Ko, C. M., Jun 1 2007, In : Journal of Endocrinology. 193, 3, p. 383-391 9 p.

Research output: Contribution to journalArticle

Endothelin-2
Endothelin A Receptors
Oviducts
Germ Cells
Endothelin Receptors

Endothelin-2 in ovarian follicle rupture

Ko, C., Gieske, M. C., Al-Alem, L., Hahn, Y. K., Su, W., Gong, M. C., Iglarz, M. & Koo, Y., Apr 1 2006, In : Endocrinology. 147, 4, p. 1770-1779 10 p.

Research output: Contribution to journalArticle

Endothelin-2
Ovarian Follicle
Rupture
Ovulation
Ovary

Endothelin B receptor is not required but necessary for finite regulation of ovulation

Cho, J., Kim, H., Kang, D. W., Yanagisawa, M. & Ko, C., Oct 15 2012, In : Life Sciences. 91, 13-14, p. 613-617 5 p.

Research output: Contribution to journalArticle

Endothelin B Receptors
Endothelins
Ovulation
Ovary
Corpus Luteum

Endothelins in regulating ovarian and oviductal function

Bridges, P. J., Cho, J. & Ko, C., Jan 1 2011, In : Frontiers in Bioscience - Scholar. 3 S, 1, p. 145-155 11 p.

Research output: Contribution to journalArticle

Endothelins
Ligands
Luteolysis
Peptide Hormones
Ovulation

Epididymal hypo-osmolality induces abnormal sperm morphology and function in the estrogen receptor alpha knockout mouse

Joseph, A., Shur, B. D., Ko, C., Chambon, P. & Hess, R. A., May 1 2010, In : Biology of reproduction. 82, 5, p. 958-967 10 p.

Research output: Contribution to journalArticle

Estrogen Receptor alpha
Knockout Mice
Osmolar Concentration
Spermatozoa
Epididymis

ERα/E2 signaling suppresses the expression of steroidogenic enzyme genes via cross-talk with orphan nuclear receptor Nur77 in the testes

Lee, S. Y., Park, E., Kim, S. C., Ahn, R. S., Ko, C. & Lee, K., Oct 15 2012, In : Molecular and Cellular Endocrinology. 362, 1-2, p. 91-103 13 p.

Research output: Contribution to journalArticle

Nuclear Receptor Subfamily 4, Group A, Member 1
Estrogen Receptor alpha
Testis
Genes
Leydig Cells

Estradiol synthesis in gut-associated lymphoid tissue: Leukocyte regulation by a sexually monomorphic system

Oakley, O. R., Kim, K. J., Lin, P. C., Barakat, R., Cacioppo, J. A., Li, Z., Whitaker, A., Chung, K. C., Mei, W. & Ko, C. M., Dec 2016, In : Endocrinology. 157, 12, p. 4579-4587 9 p.

Research output: Contribution to journalArticle

Lymphoid Tissue
Estradiol
Leukocytes
Aromatase
Peyer's Patches

Estrogen receptor (ESR) 2 partially offsets the absence of ESR1 in gonadotropes of pituitary-specific Esr1 knockout female mice

Sánchez-Criado, J. E., Trudgen, K., Millán, Y., Blanco, A., Monterde, J., Garrido-Gracia, J. C., Gordon, A., Aguilar, R., De Las Mulas, J. M. & Ko, C. M., Apr 1 2012, In : Reproduction. 143, 4, p. 549-558 10 p.

Research output: Contribution to journalArticle

Estrogen Receptor beta
Knockout Mice
Oils
Anterior Pituitary Gland
Estrogen Receptor alpha

Estrogen receptor alpha (ESR1)-dependent regulation of the mouse oviductal transcriptome

Cerny, K. L., Ribeiro, R. A. C., Jeoung, M., Ko, C. M. & Bridges, P. J., Jan 1 2016, In : PloS one. 11, 1, e0147685.

Research output: Contribution to journalArticle

Oviducts
Estrogen Receptor alpha
oviducts
Transcriptome
transcriptome

Estrogen receptor α-induced cholecystokinin type A receptor expression in the female mouse pituitary

Kim, H. J., Gieske, M. C., Hudgins, S., Kim, B. G., Krust, A., Chambon, P. & Ko, C. M., Dec 1 2007, In : Journal of Endocrinology. 195, 3, p. 393-405 13 p.

Research output: Contribution to journalArticle

Cholecystokinin A Receptor
Estrogen Receptors
Estrogens
Gonadotropin-Releasing Hormone
Proestrus

Estrogen receptor α in T cells suppresses follicular helper T cell responses and prevents autoimmunity

Kim, D. H., Park, H. J., Park, H. S., Lee, J. U., Ko, C. M., Gye, M. C. & Choi, J. M., Apr 1 2019, In : Experimental and Molecular Medicine. 51, 4, 41.

Research output: Contribution to journalArticle

Open Access
T-cells
Estrogen Receptor alpha
Helper-Inducer T-Lymphocytes
Autoimmunity
Estrogen Receptors

Estrogens in male physiology

Cooke, P. S., Nanjappa, M. K., Ko, C., Prins, G. S. & Hess, R. A., Jul 2017, In : Physiological Reviews. 97, 3, p. 995-1043 49 p.

Research output: Contribution to journalArticle

Estrogens
Reproduction
Aromatase
G-Protein-Coupled Receptors
Estrogen Receptors

Expression of an intracisternal A-particle-like element in rat ovary

Graham, K. M., Ko, C., Park, K. S., Sarge, K. & Park-Sarge, O. K., Nov 11 2000, In : Biochemical and Biophysical Research Communications. 278, 1, p. 48-57 10 p.

Research output: Contribution to journalArticle

Intracisternal A-Particle Genes
Rats
Ovary
Granulosa Cells
Genes

Expression of genomic functional estrogen receptor 1 in mouse sertoli cells

Lin, J., Zhu, J., Li, X., Li, S., Lan, Z., Ko, J. & Lei, Z., Nov 12 2014, In : Reproductive Sciences. 21, 11, p. 1411-1422 12 p.

Research output: Contribution to journalArticle

Estrogen Receptor alpha
Sertoli Cells
Estrogens
Chromatin Immunoprecipitation
Small Interfering RNA

Expression pattern of endothelin system components and localization of smooth muscle cells in the human pre-ovulatory follicle

Choi, D. H., Kim, E. K., Kim, K. H., Lee, K. A., Kang, D. W., Kim, H. Y., Bridges, P. & Ko, C., May 2011, In : Human Reproduction. 26, 5, p. 1171-1180 10 p.

Research output: Contribution to journalArticle

Theca Cells
Endothelins
Smooth Muscle Myocytes
Endothelin-2
Endothelin A Receptors

Follicle-stimulating hormone-responsive cytoskeletal genes in rat granulosa cells: Class I β-tubulin, tropomyosin-4, and kinesin heavy chain

Grieshaber, N. A., Ko, C., Grieshaber, S. S., Ji, I. & Ji, T. H., Jan 1 2003, In : Endocrinology. 144, 1, p. 29-39 11 p.

Research output: Contribution to journalArticle

Kinesin
Tropomyosin
Granulosa Cells
Follicle Stimulating Hormone
Tubulin

Follicle-stimulating hormone suppresses cytosolic 3,5,3′-triiodothyronine-binding protein messenger ribonucleic acid expression in rat granulosa cells

Ko, C., Grieshaber, N. A., Ji, I. & Ji, T. H., Jun 1 2003, In : Endocrinology. 144, 6, p. 2360-2367 8 p.

Research output: Contribution to journalArticle

Granulosa Cells
Follicle Stimulating Hormone
RNA
Ovary
Down-Regulation

Generation and characterization of an endothelin-2 iCre mouse

Cacioppo, J. A., Koo, Y., Lin, P. C. P., Gal, A. & Ko, C., Feb 1 2015, In : Genesis. 53, 2, p. 245-256 12 p.

Research output: Contribution to journalArticle

Endothelin-2
Genes
Gene Deletion
Genome
Cre recombinase

Generation and characterization of an estrogen receptor alpha-iCre knock-in mouse

Park, C. J., Chen, G., Koo, Y., Lin, P. C. P., Cacioppo, J. A., Prohaska, H. & Ko, C. M. J., Dec 2017, In : Genesis. 55, 12, e23084.

Research output: Contribution to journalArticle

Estrogen Receptor alpha
Knockout Mice
Codon
Estrogen Receptors
Transgenic Mice

Generation of an estrogen receptor beta-iCre knock-in mouse

Cacioppo, J. A., Koo, Y., Lin, P. C. P., Osmulski, S. A., Ko, C. D. & Ko, C., Jan 1 2016, In : Genesis. 54, 1, p. 38-52 15 p.

Research output: Contribution to journalArticle

Estrogen Receptor beta
Estrogen Receptors
Polyadenylation
Neomycin
Initiator Codon

Generation of Cyp17iCre transgenic mice and their application to conditionally delete estrogen receptor alpha (Esr1) from the ovary and testis

Bridges, P. J., Koo, Y., Kang, D. W., Hudgins-Spivey, S., Lan, Z. J., Xu, X., DeMayo, F., Cooney, A. & Ko, C. M., Dec 31 2008, In : Genesis. 46, 9, p. 499-505 7 p.

Research output: Contribution to journalArticle

Estrogen Receptor alpha
Transgenic Mice
Theca Cells
Testis
Ovary

Generation of red fluorescent protein transgenic dogs

Hong, S. G., Kim, M. K., Jang, G., Oh, H. J., Park, J. E., Kang, J. T., Koo, O. J., Kim, T., Kwon, M. S., Koo, B. C., Ra, J. C., Kim, D. Y., Ko, C. M. & Lee, B. C., Jun 4 2009, In : Genesis. 47, 5, p. 314-322 9 p.

Research output: Contribution to journalArticle

Dogs
Fibroblasts
Inborn Genetic Diseases
Human Development
Retroviridae

Generation of transgenic dogs that conditionally express green fluorescent protein

Kim, M. J., Oh, H. J., Park, J. E., Kim, G. A., Hong, S. G., Jang, G., Kwon, M. S., Koo, B. C., Kim, T., Kang, S. K., Ra, J. C., Ko, C. & Lee, B. C., Jun 1 2011, In : Genesis. 49, 6, p. 472-478 7 p.

Research output: Contribution to journalArticle

Green Fluorescent Proteins
Dogs
Doxycycline
Transgenes
Oocytes

GEPRO: Gene expression profiler for DNA microarray data

Kim, B. G., Lindemann, M. D., Bridges, P. J. & Ko, C., Jan 1 2009, In : Revista Colombiana de Ciencias Pecuarias. 22, 1, p. 12-18 7 p.

Research output: Contribution to journalArticle

Oligonucleotide Array Sequence Analysis
Gene Expression
gene expression
researchers
Research Personnel

Granulosa cell endothelin-2 expression is fundamental for ovulatory follicle rupture

Cacioppo, J. A., Lin, P. C. P., Hannon, P. R., McDougle, D. R., Gal, A. & Ko, C., Dec 1 2017, In : Scientific reports. 7, 1, 817.

Research output: Contribution to journalArticle

Endothelin-2
Granulosa Cells
Oocytes
Rupture
Ovulation

Hematopoetic prostaglandin D synthase: An ESR1-dependent oviductal epithelial cell synthase

Bridges, P. J., Jeoung, M., Shim, S., Park, J. Y., Lee, J. E., Sapsford, L. A., Trudgen, K., Ko, C., Gye, M. C. & Jo, M., Apr 1 2012, In : Endocrinology. 153, 4, p. 1925-1935 11 p.

Research output: Contribution to journalArticle

prostaglandin R2 D-isomerase
Epithelial Cells
Oviducts
Inflammation
Epithelium
Estrogen Receptor beta
Monoclonal Antibodies
Tissue
Antibodies
Granulosa Cells

Identification of a novel role for endothelins within the oviduct

Jeoung, M., Lee, S., Hawng, H. K., Cheon, Y. P., Jeong, Y. K., Gye, M. C., Iglarz, M., Ko, C. & Bridges, P. J., Jun 1 2010, In : Endocrinology. 151, 6, p. 2858-2867 10 p.

Research output: Contribution to journalArticle

Oviducts
Endothelins
Fertilization
Embryonic Development
Epithelial Cells

Identification of estradiol/ERα-regulated genes in the mouse pituitary

Kim, H. J., Gieske, M. C., Trudgen, K. L., Hudgins-Spivey, S., Kim, B. G., Krust, A., Chambon, P., Jeong, J. W., Blalock, E. & Ko, C. M., Sep 1 2011, In : Journal of Endocrinology. 210, 3, p. 309-321 13 p.

Research output: Contribution to journalArticle

Estradiol Receptors
Estrogen Receptors
Estrogens
Genes
Gonadotropin-Releasing Hormone

IGF1R expression in ovarian granulosa cells is essential for steroidogenesis, follicle survival, and fertility in female mice

Baumgarten, S. C., Armouti, M., Ko, C. & Stocco, C., Jul 2017, In : Endocrinology. 158, 7, p. 2309-2318 10 p.

Research output: Contribution to journalArticle

Growth Factor Receptors
Granulosa Cells
Fertility
Follicle Stimulating Hormone
Ovary

Increased morbidity and mortality in murine cytomegalovirusinfected mice following allogeneic bone marrow transplant is associated with reduced surface decay accelerating factor expression

El-Amouri, I. S., Bani-Ahmad, M., Tang-Feldman, Y., Lin, F., Ko, C., Pomeroy, C. & Oakley, O. R., Nov 1 2010, In : Clinical and Experimental Immunology. 162, 2, p. 379-391 13 p.

Research output: Contribution to journalArticle

CD55 Antigens
Muromegalovirus
Homologous Transplantation
Bone Marrow Transplantation
Cytomegalovirus Infections

Label-free, multi-scale imaging of ex-vivo mouse brain using spatial light interference microscopy

Min, E., Kandel, M. E., Ko, C. J., Popescu, G., Jung, W. & Best-Popescu, C., Dec 23 2016, In : Scientific reports. 6, 39667.

Research output: Contribution to journalArticle

Interference Microscopy
Light
Brain
Corpus Callosum
Olfactory Bulb

Leucine-rich repeat kinase 2 exacerbates neuronal cytotoxicity through phosphorylation of histone deacetylase 3 and histone deacetylation

Han, K. A., Shin, W. H., Jung, S., Seol, W., Seo, H., Ko, C. & Chung, K. C., Jan 1 2017, In : Human molecular genetics. 26, 1, p. 1-18 18 p.

Research output: Contribution to journalArticle

Leucine
Histones
Phosphotransferases
Phosphorylation
Oxidopamine

Loss of Fertility in the Absence of Progesterone Receptor Expression in Kisspeptin Neurons of Female Mice

Gal, A., Lin, P. C., Cacioppo, J. A., Hannon, P. R., Mahoney, M. M., Wolfe, A., Fernandez-Valdivia, R., Lydon, J. P., Elias, C. F. & Ko, C. M., Jul 2016, In : PloS one. 11, 7, e0159534.

Research output: Contribution to journalArticle

Kisspeptins
gonadotropin-releasing hormone
Progesterone Receptors
hypothalamus
Neurons

Loss of function of endothelin-2 leads to reduced ovulation and CL formation

Cacioppo, J. A., Oh, S. W., Kim, H. Y., Cho, J., Lin, P. C. P., Yanagisawa, M. & Ko, C. M., Apr 24 2014, In : PloS one. 9, 4, e96115.

Research output: Contribution to journalArticle

Endothelin-2
endothelins
Corpus Luteum
Ovulation
corpus luteum

Methodology matters: IVF versus ICSI and embryonic gene expression

Bridges, P. J., Jeoung, M., Kim, H., Kim, J. H., Lee, D. R., Ko, C. & Baker, D. J., Aug 1 2011, In : Reproductive BioMedicine Online. 23, 2, p. 234-244 11 p.

Research output: Contribution to journalArticle

Intracytoplasmic Sperm Injections
Gene Expression
Blastocyst
Oocytes
Microarray Analysis

Obesity-induced infertility and hyperandrogenism are corrected by deletion of the insulin receptor in the ovarian theca cell

Wu, S., Divall, S., Nwaopara, A., Radovick, S., Wondisford, F., Ko, C. M. & Wolfe, A., Apr 1 2014, In : Diabetes. 63, 4, p. 1270-1282 13 p.

Research output: Contribution to journalArticle

Theca Cells
Hyperandrogenism
Insulin Receptor
Infertility
Obesity

Partial cloning and expression pattern analyses of fibroblast growth factor-like cDNA in Xenopus oocytes

Kim, H. H., Ko, C., Chung, H. M., Kim, W. S. & Nham, S. U., Dec 1 1997, In : Korean Journal of Genetics. 19, 3, p. 257-265 9 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factors
Cloning
Xenopus
Oocytes
Notochord

Partial cloning of Xhox3.1 gene in Xenopus laevis

Kim, T. K., Ko, C., Nham, S. U. & Chung, H. M., Dec 1 1996, In : Korean Journal of Genetics. 18, 2, p. 111-116 6 p.

Research output: Contribution to journalArticle

Cloning
Xenopus laevis
Organism Cloning
Homeobox Genes
Complementary DNA