If you made any changes in Pure these will be visible here soon.

Research Output

2020

Core Binding Factors are essential for ovulation, luteinization, and female fertility in mice

Lee-Thacker, S., Jeon, H., Choi, Y., Taniuchi, I., Takarada, T., Yoneda, Y., Ko, C. M. & Jo, M., Dec 1 2020, In : Scientific reports. 10, 1, 9921.

Research output: Contribution to journalArticle

Open Access

Germline-dependent transmission of male reproductive traits induced by an endocrine disruptor, di-2-ethylhexyl phthalate, in future generations

Barakat, R., Lin, P. C., Park, C. J., Zeineldin, M., Zhou, S., Rattan, S., Brehm, E., Flaws, J. A. & Ko, C. M. J., Dec 1 2020, In : Scientific reports. 10, 1, 5705.

Research output: Contribution to journalArticle

Open Access

Progesterone Receptor Serves the Ovary as a Trigger of Ovulation and a Terminator of Inflammation

Park, C. J., Lin, P. C., Zhou, S., Barakat, R., Bashir, S. T., Choi, J. M., Cacioppo, J. A., Oakley, O. R., Duffy, D. M., Lydon, J. P. & Ko, C. M. J., Apr 14 2020, In : Cell Reports. 31, 2, 107496.

Research output: Contribution to journalArticle

Open Access
2019

Estrogen receptor α in T cells suppresses follicular helper T cell responses and prevents autoimmunity

Kim, D. H., Park, H. J., Park, H. S., Lee, J. U., Ko, C. M., Gye, M. C. & Choi, J. M., Apr 1 2019, In : Experimental and Molecular Medicine. 51, 4, 41.

Research output: Contribution to journalArticle

Open Access

Ovulation: Parallels with inflammatory processes

Duffy, D. M., Ko, C., Jo, M., Brannstrom, M. & Curry, T. E., Jan 1 2019, In : Endocrine reviews. 40, 2, p. 369-416 48 p.

Research output: Contribution to journalReview article

Prenatal exposure to an environmentally relevant phthalate mixture disrupts testicular steroidogenesis in adult male mice

Barakat, R., Seymore, T., Lin, P. C. P., Park, C. J. & Ko, C. M. J., May 2019, In : Environmental Research. 172, p. 194-201 8 p.

Research output: Contribution to journalArticle

Sanitary pads and diapers contain higher phthalate contents than those in common commercial plastic products

Park, C. J., Barakat, R., Ulanov, A., Li, Z., Lin, P. C., Chiu, K., Zhou, S., Perez, P., Lee, J., Flaws, J. & Ko, C. M. J., Mar 2019, In : Reproductive Toxicology. 84, p. 114-121 8 p.

Research output: Contribution to journalArticle

2018

Core binding factor b expression in ovarian granulosa cells is essential for female fertility

Lee-Thacker, S., Choi, Y., Taniuchi, I., Takarada, T., Yoneda, Y., Ko, C. M. & Jo, M., May 1 2018, In : Endocrinology. 159, 5, p. 2094-2109 16 p.

Research output: Contribution to journalArticle

Female antiandrogens

Barakat, R. & Ko, C. M. J., Jan 1 2018, Encyclopedia of Reproduction. Elsevier, p. 748-752 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Female antiestrogens

Barakat, R., Park, C. J., Perez, P. A., Chiu, K. & Ko, C. M., Jan 1 2018, Encyclopedia of Reproduction. Elsevier, p. 740-747 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Porcine intestinal lymphoid tissues synthesize estradiol

Park, C. J., Kim, H., Jin, J., Barakat, R., Lin, P. C., Choi, J. M. & Ko, C. M. J., Jan 1 2018, In : Journal of Veterinary Science. 19, 4, p. 477-482 6 p.

Research output: Contribution to journalArticle

Prenatal exposure to DEHP induces neuronal degeneration and neurobehavioral abnormalities in adult male mice

Barakat, R., Lin, P. C., Park, C. J., Best-Popescu, C., Bakry, H. H., Abosalem, M. E., Abdelaleem, N. M., Flaws, J. A. & Ko, C. M., Jan 1 2018, In : Toxicological Sciences. 164, 2, p. 439-452 14 p.

Research output: Contribution to journalArticle

2017

Androgen receptor in the ovary theca cells plays a critical role in androgen-induced reproductive dysfunction

Ma, Y., Andrisse, S., Chen, Y., Childress, S., Xue, P., Wang, Z., Jones, D., Ko, C., Divall, S. & Wu, S., Jan 1 2017, In : Endocrinology. 158, 1, p. 98-108 11 p.

Research output: Contribution to journalArticle

Birth of clones of the world's first cloned dog

Kim, M. J., Oh, H. J., Kim, G. A., Setyawan, E. M. N., Choi, Y. B., Lee, S. H., Petersen-Jones, S. M., Ko, C. M. J. & Lee, B. C., Dec 1 2017, In : Scientific reports. 7, 1, 15235.

Research output: Contribution to journalArticle

Estrogens in male physiology

Cooke, P. S., Nanjappa, M. K., Ko, C., Prins, G. S. & Hess, R. A., Jul 2017, In : Physiological Reviews. 97, 3, p. 995-1043 49 p.

Research output: Contribution to journalArticle

Generation and characterization of an estrogen receptor alpha-iCre knock-in mouse

Park, C. J., Chen, G., Koo, Y., Lin, P. C. P., Cacioppo, J. A., Prohaska, H. & Ko, C. M. J., Dec 2017, In : Genesis. 55, 12, e23084.

Research output: Contribution to journalArticle

Granulosa cell endothelin-2 expression is fundamental for ovulatory follicle rupture

Cacioppo, J. A., Lin, P. C. P., Hannon, P. R., McDougle, D. R., Gal, A. & Ko, C., Dec 1 2017, In : Scientific reports. 7, 1, 817.

Research output: Contribution to journalArticle

IGF1R expression in ovarian granulosa cells is essential for steroidogenesis, follicle survival, and fertility in female mice

Baumgarten, S. C., Armouti, M., Ko, C. & Stocco, C., Jul 2017, In : Endocrinology. 158, 7, p. 2309-2318 10 p.

Research output: Contribution to journalArticle

Leucine-rich repeat kinase 2 exacerbates neuronal cytotoxicity through phosphorylation of histone deacetylase 3 and histone deacetylation

Han, K. A., Shin, W. H., Jung, S., Seol, W., Seo, H., Ko, C. M. & Chung, K. C., Jan 1 2017, In : Human molecular genetics. 26, 1, p. 1-18 18 p.

Research output: Contribution to journalArticle

Prenatal exposure to DEHP induces premature reproductive senescence in male mice

Barakat, R., Lin, P. C. P., Rattan, S., Brehm, E., Canisso, I. F., Abosalum, M. E., Flaws, J. A., Hess, R. & Ko, C. M., Mar 1 2017, In : Toxicological Sciences. 156, 1, p. 96-108 13 p.

Research output: Contribution to journalArticle

Selective deletion of Pten in theca-interstitial cells leads to androgen excess and ovarian dysfunction in mice

Lan, Z. J., Krause, M. S., Redding, S. D., Li, X., Wu, G. Z., Zhou, H. X., Bohler, H. C., Ko, C., Cooney, A. J., Zhou, J. & Lei, Z. M., Mar 15 2017, In : Molecular and Cellular Endocrinology. 444, p. 26-37 12 p.

Research output: Contribution to journalArticle

2016

Conditional deletion of Bmal1 in ovarian theca cells disrupts ovulation in female mice

Mereness, A. L., Murphy, Z. C., Forrestel, A. C., Butler, S., Ko, C. M., Richards, J. A. S. & Sellix, M. T., Feb 2016, In : Endocrinology. 157, 2, p. 913-927 15 p.

Research output: Contribution to journalArticle

Estradiol synthesis in gut-associated lymphoid tissue: Leukocyte regulation by a sexually monomorphic system

Oakley, O. R., Kim, K. J., Lin, P. C., Barakat, R., Cacioppo, J. A., Li, Z., Whitaker, A., Chung, K. C., Mei, W. & Ko, C. M., Dec 2016, In : Endocrinology. 157, 12, p. 4579-4587 9 p.

Research output: Contribution to journalArticle

Estrogen receptor alpha (ESR1)-dependent regulation of the mouse oviductal transcriptome

Cerny, K. L., Ribeiro, R. A. C., Jeoung, M., Ko, C. M. & Bridges, P. J., Jan 1 2016, In : PloS one. 11, 1, e0147685.

Research output: Contribution to journalArticle

Extra-gonadal sites of estrogen biosynthesis and function

Barakat, R., Oakley, O., Kim, H., Jin, J. & Ko, C. M. J., Jan 1 2016, In : BMB Reports. 49, 9, p. 488-496 9 p.

Research output: Contribution to journalShort survey

Generation of an estrogen receptor beta-iCre knock-in mouse

Cacioppo, J. A., Koo, Y., Lin, P. C. P., Osmulski, S. A., Ko, C. D. & Ko, C., Jan 1 2016, In : Genesis. 54, 1, p. 38-52 15 p.

Research output: Contribution to journalArticle

Label-free, multi-scale imaging of ex-vivo mouse brain using spatial light interference microscopy

Min, E., Kandel, M. E., Ko, C. J., Popescu, G., Jung, W. & Best-Popescu, C., Dec 23 2016, In : Scientific reports. 6, 39667.

Research output: Contribution to journalArticle

Loss of Fertility in the Absence of Progesterone Receptor Expression in Kisspeptin Neurons of Female Mice

Gal, A., Lin, P. C., Cacioppo, J. A., Hannon, P. R., Mahoney, M. M., Wolfe, A., Fernandez-Valdivia, R., Lydon, J. P., Elias, C. F. & Ko, C. M., Jul 2016, In : PloS one. 11, 7, e0159534.

Research output: Contribution to journalArticle

2015

Dual suppression of estrogenic and inflammatory activities for targeting of endometriosis

Zhao, Y., Gong, P., Chen, Y., Nwachukwu, J. C., Srinivasan, S., Ko, C. M., Bagchi, M. K., Taylor, R. N., Korach, K. S., Nettles, K. W., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Jan 21 2015, In : Science Translational Medicine. 7, 271, 271ra9.

Research output: Contribution to journalArticle

Generation and characterization of an endothelin-2 iCre mouse

Cacioppo, J. A., Koo, Y., Lin, P. C. P., Gal, A. & Ko, C., Feb 1 2015, In : Genesis. 53, 2, p. 245-256 12 p.

Research output: Contribution to journalArticle

2014

Beclin-1 deficiency in the murine ovary results in the reduction of progesterone production to promote preterm labor

Gawriluk, T. R., Ko, C., Hong, X., Christenson, L. K. & Rucker, E. B., Sep 22 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 40, p. E4194-E4203

Research output: Contribution to journalArticle

Disrupted kisspeptin signaling in GnRH neurons leads to hypogonadotrophic hypogonadism

Novaira, H. J., Sonko, M. L., Hoffman, G., Koo, Y., Ko, C., Wolfe, A. & Radovick, S., Feb 1 2014, In : Molecular Endocrinology. 28, 2, p. 225-238 14 p.

Research output: Contribution to journalArticle

Expression of genomic functional estrogen receptor 1 in mouse sertoli cells

Lin, J., Zhu, J., Li, X., Li, S., Lan, Z., Ko, J. & Lei, Z., Nov 12 2014, In : Reproductive Sciences. 21, 11, p. 1411-1422 12 p.

Research output: Contribution to journalArticle

Loss of function of endothelin-2 leads to reduced ovulation and CL formation

Cacioppo, J. A., Oh, S. W., Kim, H. Y., Cho, J., Lin, P. C. P., Yanagisawa, M. & Ko, C. M., Apr 24 2014, In : PloS one. 9, 4, e96115.

Research output: Contribution to journalArticle

Obesity-induced infertility and hyperandrogenism are corrected by deletion of the insulin receptor in the ovarian theca cell

Wu, S., Divall, S., Nwaopara, A., Radovick, S., Wondisford, F., Ko, C. M. & Wolfe, A., Apr 1 2014, In : Diabetes. 63, 4, p. 1270-1282 13 p.

Research output: Contribution to journalArticle

Transforming growth factor-β1 signaling represses testicular steroidogenesis through cross-talk with orphan nuclear receptor Nur77

Park, E., Song, C. H., Park, J. I., Ahn, R. S., Choi, H. S., Ko, C. M. & Lee, K., Aug 20 2014, In : PloS one. 9, 8, e104812.

Research output: Contribution to journalArticle

Vaginal Fold Histology Reduces the Variability Introduced by Vaginal Exfoliative Cytology in the Classification of Mouse Estrous Cycle Stages

Gal, A., Lin, P. C., Barger, A. M., Macneill, A. L. & ko, C., Dec 2014, In : Toxicologic Pathology. 42, 8, p. 1212-1220 9 p.

Research output: Contribution to journalArticle

2013

A low-copy-number plasmid for retrieval of toxic genes from BACs and generation of conditional targeting constructs

Na, G., Wolfe, A., Ko, C., Youn, H., Lee, Y. M., Byun, S. J., Jeon, I. & Koo, Y., Jun 1 2013, In : Molecular Biotechnology. 54, 2, p. 504-514 11 p.

Research output: Contribution to journalArticle

RiboTag Analysis of Actively Translated mRNAs in Sertoli and Leydig Cells In Vivo

Sanz, E., Evanoff, R., Quintana, A., Evans, E., Miller, J. A., Ko, C., Amieux, P. S., Griswold, M. D. & McKnight, G. S., Jun 11 2013, In : PloS one. 8, 6, e66179.

Research output: Contribution to journalArticle

2012

Endothelin B receptor is not required but necessary for finite regulation of ovulation

Cho, J., Kim, H., Kang, D. W., Yanagisawa, M. & Ko, C., Oct 15 2012, In : Life Sciences. 91, 13-14, p. 613-617 5 p.

Research output: Contribution to journalArticle

ERα/E2 signaling suppresses the expression of steroidogenic enzyme genes via cross-talk with orphan nuclear receptor Nur77 in the testes

Lee, S. Y., Park, E., Kim, S. C., Ahn, R. S., Ko, C. M. & Lee, K., Oct 15 2012, In : Molecular and Cellular Endocrinology. 362, 1-2, p. 91-103 13 p.

Research output: Contribution to journalArticle

Estrogen receptor (ESR) 2 partially offsets the absence of ESR1 in gonadotropes of pituitary-specific Esr1 knockout female mice

Sánchez-Criado, J. E., Trudgen, K., Millán, Y., Blanco, A., Monterde, J., Garrido-Gracia, J. C., Gordon, A., Aguilar, R., De Las Mulas, J. M. & Ko, C. M., Apr 1 2012, In : Reproduction. 143, 4, p. 549-558 10 p.

Research output: Contribution to journalArticle

Hematopoetic prostaglandin D synthase: An ESR1-dependent oviductal epithelial cell synthase

Bridges, P. J., Jeoung, M., Shim, S., Park, J. Y., Lee, J. E., Sapsford, L. A., Trudgen, K., Ko, C., Gye, M. C. & Jo, M., Apr 1 2012, In : Endocrinology. 153, 4, p. 1925-1935 11 p.

Research output: Contribution to journalArticle

Why two endothelins and two receptors for ovulation and luteal regulation?

Ko, C., Meidan, R. & Bridges, P. J., Oct 15 2012, In : Life Sciences. 91, 13-14, p. 501-506 6 p.

Research output: Contribution to journalArticle

2011

Endothelins in regulating ovarian and oviductal function

Bridges, P. J., Cho, J. & Ko, C., Jan 1 2011, In : Frontiers in Bioscience - Scholar. 3 S, 1, p. 145-155 11 p.

Research output: Contribution to journalArticle

Expression pattern of endothelin system components and localization of smooth muscle cells in the human pre-ovulatory follicle

Choi, D. H., Kim, E. K., Kim, K. H., Lee, K. A., Kang, D. W., Kim, H. Y., Bridges, P. & Ko, C., May 2011, In : Human Reproduction. 26, 5, p. 1171-1180 10 p.

Research output: Contribution to journalArticle

Generation of transgenic dogs that conditionally express green fluorescent protein

Kim, M. J., Oh, H. J., Park, J. E., Kim, G. A., Hong, S. G., Jang, G., Kwon, M. S., Koo, B. C., Kim, T., Kang, S. K., Ra, J. C., Ko, C. & Lee, B. C., Jun 1 2011, In : Genesis. 49, 6, p. 472-478 7 p.

Research output: Contribution to journalArticle

Identification of estradiol/ERα-regulated genes in the mouse pituitary

Kim, H. J., Gieske, M. C., Trudgen, K. L., Hudgins-Spivey, S., Kim, B. G., Krust, A., Chambon, P., Jeong, J. W., Blalock, E. & Ko, C. M., Sep 1 2011, In : Journal of Endocrinology. 210, 3, p. 309-321 13 p.

Research output: Contribution to journalArticle

Methodology matters: IVF versus ICSI and embryonic gene expression

Bridges, P. J., Jeoung, M., Kim, H., Kim, J. H., Lee, D. R., Ko, C. & Baker, D. J., Aug 1 2011, In : Reproductive BioMedicine Online. 23, 2, p. 234-244 11 p.

Research output: Contribution to journalArticle

Pituitary-ovary-spleen axis in ovulation

Oakley, O. R., Frazer, M. L. & Ko, C. M., Sep 1 2011, In : Trends in Endocrinology and Metabolism. 22, 9, p. 345-352 8 p.

Research output: Contribution to journalReview article