Benita S Katzenellenbogen

1970 …2018
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Research Output 1970 2018

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Article
1988

Plasminogen activators in human breast cancer cell lines: Hormonal regulation and properties

Mangel, W. F., Toledo, D. L., Nardulli, A. M., Reiner, G. C. A., Norman, M. J. & Katzenellenbogen, B. S., 1988, In : Journal of Steroid Biochemistry. 30, 1-6, p. 79-88 10 p.

Research output: Contribution to journalArticle

Plasminogen Activators
Cells
Breast Neoplasms
Cell Line
Estrogen Receptors
Progestins
Progesterone Receptors
Cell Count
Promegestone
Breast Neoplasms
MCF-7 Cells
Progesterone Receptors
Estradiol
Estrogens
RNA
Chloramphenicol O-Acetyltransferase
Estrogen Receptor Modulators
Gene Fusion
Gene Expression Regulation
Estrogens
1989

Identification of cysteine 530 as the covalent attachment site of an affinity-labeling estrogen (ketononestrol aziridine) and antiestrogen (tamoxifen aziridine) in the human estrogen receptor

Harlow, K. W., Smith, D. N., Katzenellenbogen, J. A., Greene, G. L. & Katzenellenbogen, B. S., 1989, In : Journal of Biological Chemistry. 264, 29, p. 17476-17485 10 p.

Research output: Contribution to journalArticle

Estrogen Receptor Modulators
Estrogen Receptors
Labeling
Cysteine
Estrogens

Progression of human breast cancer cells from hormone-dependent to hormone-independent growth both in vitro and in vivo

Clarke, R., Brunner, N., Katzenellenbogen, B. S., Thompson, E. W., Norman, M. J., Koppi, C., Paik, S., Lippman, M. E. & Dickson, R. B., Jan 1 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 10, p. 3649-3653 5 p.

Research output: Contribution to journalArticle

Growth Hormone
Hormones
Breast Neoplasms
Phenotype
Estrogens
Hormone Antagonists
Gonadal Steroid Hormones
Estrogen Receptors
Intercellular Signaling Peptides and Proteins
RNA
1990
Estrogen Receptors
Chromatin
Formaldehyde
Breast Neoplasms
Ligands

Hormonal Modulation of HER-2/neu Protooncogene Messenger Ribonucleic Acid and pl85 Protein Expression in Human Breast Cancer Cell Lines

Read, L. D., Keith, D., Slamon, D. J. & Katzenellenbogen, B. S., Jul 1 1990, In : Cancer Research. 50, 13, p. 3947-3951 5 p.

Research output: Contribution to journalArticle

RNA
Breast Neoplasms
Cell Line
Messenger RNA
Progestins
Somatomedins
Progesterone Receptors
Estrogens
Insulin
Breast Neoplasms
1991
Estrogen Receptor Modulators
Response Elements
Estrogen Receptors
Estradiol
DNA
Gene Expression Regulation
Estrogen Receptors
Estrogens
Breast Neoplasms
Messenger RNA

Efficient and Selective Photoaffinity Labeling of the Estrogen Receptor Using Two Nonsteroidal Ligands That Embody Aryl Azide or Tetrafluoroaryl Azide Photoreactive Functions

Pinney, K. G., Carlson, K. E., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Mar 1 1991, In : Biochemistry. 30, 9, p. 2421-2431 11 p.

Research output: Contribution to journalArticle

Azides
Estrogen Receptors
Labeling
Ligands
Tritium
Mutagenesis
Estrogen Receptors
Transcriptional Activation
Cysteine
Chemical activation
Estrogen Receptor Modulators
Somatomedins
Progesterone Receptors
Protein Kinase Inhibitors
Adenosine
1992

Characterization and regulation of estrogen and progesterone receptors in breast cancer.

Read, L. D. & Katzenellenbogen, B. S., 1992, In : Cancer Treatment and Research. 61, p. 277-299 23 p.

Research output: Contribution to journalArticle

Neoplastic Gene Expression Regulation
Hormone-Dependent Neoplasms
Neoplasm Proteins
Growth Substances
Progestins
Cell Extracts
Estrogen Receptors
Transcriptional Activation
Chemical activation
Hormones
Estrogen Receptor Modulators
Estrogen Receptors
Transcriptional Activation
Hormones
DNA

Human estrogen receptor mutants with altered estrogen and antiestrogen ligand discrimination

Pakdel, F. & Katzenellenbogen, B. S., Jan 1 1992, In : Journal of Biological Chemistry. 267, 5, p. 3429-3437 9 p.

Research output: Contribution to journalArticle

Estrogen Receptor Modulators
Estrogen Receptors
Estrogens
Ligands
Amino Acids
Estrogen Receptors
Transcriptional Activation
Cysteine
Ligands
Estrogen Receptor Modulators
Estrogen Receptors
Yeasts
Ligands
Bacteria
Amino Acids
1993
Bioactivity
Estrogen Receptors
Half-Life
Mutagenesis
Proteins

Cloning of the rat progesterone receptor gene 5'-region and identification of two functionally distinct promoters

Kraus, W. L., Montano, M. M. & Katzenellenbogen, B. S., Dec 1993, In : Molecular Endocrinology. 7, 12, p. 1603-1616 14 p.

Research output: Contribution to journalArticle

Chloramphenicol O-Acetyltransferase
Progesterone Receptors
Organism Cloning
Estrogen Receptors
Genes

Estrogen receptors: Ligand discrimination and antiestrogen action

Katzenellenbogen, B. S., Fang, H., Ince, B. A., Pakdel, F., Reese, J. C., Wooge, C. H. & Wrenn, C. K., Jan 1 1993, In : Breast Cancer Research and Treatment. 27, 1-2, p. 17-26 10 p.

Research output: Contribution to journalArticle

Estrogen Receptor Modulators
Estrogen Receptors
Ligands
Estrogens
Hormones

Hormone binding and transcription activation by estrogen receptors: Analyses using mammalian and yeast systems

Katzenellenbogen, B. S., Bhardwaj, B., Fang, H., Ince, B. A., Pakde, F., Reese, J. C., Schodin, D. & Wrenn, C. K., Dec 1993, In : Journal of Steroid Biochemistry and Molecular Biology. 47, 1-6, p. 39-48 10 p.

Research output: Contribution to journalArticle

Transcription
Estrogen Receptors
Yeast
Transcriptional Activation
Yeasts
Estrogen Receptors
Estrogens
Hormones
Estrogen Receptor Modulators
Steroid Receptors

Powerful dominant negative mutants of the human estrogen receptor

Ince, B. A., Zhuang, Y., Wrenn, C. K., Shapiro, D. J. & Katzenellenbogen, B. S., Jan 1 1993, In : Journal of Biological Chemistry. 268, 19, p. 14026-14032 7 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Transcription
Estrogens
Response Elements
Assays
Hormone Antagonists
Gonadal Steroid Hormones
Progesterone Receptors
Uterus
Progesterone
Insulin-Like Growth Factor I
Estrogen Receptors
Cyclic AMP
Estrogens
Phosphorylation
Mutagenesis
Estrogen Receptors
Yeast
Screening
Yeasts
Estrogen Receptors
Protein Kinases
Estradiol
Chloramphenicol O-Acetyltransferase
1-Methyl-3-isobutylxanthine
1994
Estrogen Receptor Modulators
Estrogen Receptors
Adenosine
Ligands
1-Methyl-3-isobutylxanthine
Estrogen Receptor Modulators
Tamoxifen
Protein Kinases
Breast Neoplasms
Cyclic AMP-Dependent Protein Kinases
Transforming Growth Factors
Estrogens
Steroids
Breast Neoplasms
Growth

Bivalent ligands as probes of estrogen receptor action

Bergmann, K. E., Wooge, C. H., Carlson, K. E., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Jun 1994, In : Journal of Steroid Biochemistry and Molecular Biology. 49, 2-3, p. 139-152 14 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Hexestrol
Ligands
Reporter Genes
Estrogen Antagonists
Adenylyl Cyclases
Estrogens
Hormones
Genes
Nucleic Acid Synthesis Inhibitors

Identification of multiple, widely spaced estrogen-responsive regions in the rat progesterone receptor gene

Kraus, W. L., Montano, M. M. & Katzenellenbogen, B. S., Aug 1 1994, In : Molecular Endocrinology. 8, 8, p. 952-969 18 p.

Research output: Contribution to journalArticle

Progesterone Receptors
Estrogens
Genes
Response Elements
Base Pairing

Phosphorylation of the human estrogen receptor. Identification of hormone- regulated sites and examination of their influence on transcriptional activity

Le Goff, P., Montano, M. M., Schodin, D. J. & Katzenellenbogen, B. S., Jan 1 1994, In : Journal of Biological Chemistry. 269, 6, p. 4458-4466 9 p.

Research output: Contribution to journalArticle

Phosphorylation
Estrogen Receptors
Hormones
Serine
1-Methyl-3-isobutylxanthine
Progesterone Receptors
Insulin-Like Growth Factor I
Adenosine
Estradiol
Breast Neoplasms
1995

Analysis of mechanisms that determine dominant negative estrogen receptor effectiveness

Schodin, D. J., Zhuang, Y., Shapiro, D. J. & Katzenellenbogen, B. S., Dec 29 1995, In : Journal of Biological Chemistry. 270, 52, p. 31163-31171 9 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Estrogens
Dimerization
Response Elements
Mutation

Antiestrogens: Mechanisms and actions in target cells

Katzenellenbogen, B. S., Montano, M. M., Le Goff, P., Schodin, D. J., Kraus, W. L., Bhardwaj, B. & Fujimoto, N., Jun 1995, In : Journal of Steroid Biochemistry and Molecular Biology. 53, 1-6, p. 387-393 7 p.

Research output: Contribution to journalArticle

Estrogen Receptor Modulators
Estrogen Receptors
Estrogens
Phosphorylation
Protein Kinases
Response Elements
Estrogen Receptors
Estradiol
Estrogens
Cricetulus
Steroid Receptors
Progesterone Receptors
Estrogen Receptors
Hormones
Ligands
Cytoplasmic and Nuclear Receptors
Estrogen Receptors
Steroids
Ligands
Estrogens

Observations arising from the use of pure antioestrogens on oestrogen-responsive (MCF-7) and oestrogen growth-independent (K3) human breast cancer cells

Nicholson, R. I., Gee, J. M. W., Francis, A. B., Manning, D. L., Wakeling, A. E. & Katzenellenbogen, B. S., 1995, In : Endocrine-Related Cancer. 2, 1, p. 115-121 7 p.

Research output: Contribution to journalArticle

Repression of endogenous estrogen receptor activity in mcf-7 human breast cancer cells by dominant negative estrogen receptors

Ince, B. A., Schodin, D. J. & Katzenellenbogen, B. S., Aug 1995, In : Endocrinology. 136, 8, p. 3194-3199 6 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Breast Neoplasms
Estrogens
Chloramphenicol O-Acetyltransferase
Response Elements

Responses to Pure Antiestrogens (ICI 164384, ICI182780) in Estrogen‐Sensitive and‐Resistant Experimental and Clinical Breast Cancer

NICHOLSON, R. I., GEE, J. M. W., MANNING, D. L., WAKELING, A. E., MONTANO, M. M. & Katzenellenbogen, B. S., Jun 1995, In : Annals of the New York Academy of Sciences. 761, 1, p. 148-163 16 p.

Research output: Contribution to journalArticle

Estrogen Antagonists
Estrogen Receptor Modulators
Estrogen Receptors
Estrogens
Hormones
1996

Analysis of estrogen receptor transcriptional enhancement by a nuclear hormone receptor coactivator

Mcinerney, E. M., Tsai, M. J., O'Malley, B. W. & Katzenellenbogen, B. S., Sep 17 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 19, p. 10069-10073 5 p.

Research output: Contribution to journalArticle

Nuclear Receptor Coactivators
Cytoplasmic and Nuclear Receptors
Estrogen Receptors
Ligands
Nuclear Receptor Coactivator 1

A transcriptionally active estrogen receptor mutant is a novel type of dominant negative inhibitor of estrogen action

McInerney, E. M., Ince, B. A., Shapiro, D. J. & Katzenellenbogen, B. S., Dec 17 1996, In : Molecular Endocrinology. 10, 12, p. 1519-1526 8 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Estrogens
Response Elements
DNA
Amino Acid Substitution