Benita S Katzenellenbogen

1970 …2020
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Research Output 1970 2020

Repression of endogenous estrogen receptor activity in mcf-7 human breast cancer cells by dominant negative estrogen receptors

Ince, B. A., Schodin, D. J. & Katzenellenbogen, B. S., Aug 1995, In : Endocrinology. 136, 8, p. 3194-3199 6 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Breast Neoplasms
Estrogens
Chloramphenicol O-Acetyltransferase
Response Elements

Repressor of Estrogen Receptor Activity (REA) is essential for mammary gland morphogenesis and functional activities: Studies in conditional knockout mice

Park, S., Zhao, Y., Yoon, S., Xu, J., Liao, L., Lydon, J., DeMayo, F., O'Malley, B. W. & Katzenellenbogen, B. S., Nov 1 2011, In : Endocrinology. 152, 11, p. 4336-4349 14 p.

Research output: Contribution to journalArticle

Human Mammary Glands
Morphogenesis
Knockout Mice
Estrogen Receptors
Breast

Respective role of membrane and nuclear estrogen receptor (ER) α in the mandible of growing mice: Implications for ERα modulation

Vinel, A., Coudert, A. E., Buscato, M., Valera, M. C., Ostertag, A., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Berdal, A., Babajko, S., Arnal, J. F. & Fontaine, C., Aug 2018, In : Journal of Bone and Mineral Research. 33, 8, p. 1520-1531 12 p.

Research output: Contribution to journalArticle

Mandible
Estrogen Receptors
Bone and Bones
Membranes
Estrogens

Response-specific and ligand dose-dependent modulation of estrogen receptor (ER) α activity by ERβ in the uterus

Frasor, J., Barnett, D. H., Danes, J. M., Hess, R. A., Parlow, A. F. & Katzenellenbogen, B. S., Jul 1 2003, In : Endocrinology. 144, 7, p. 3159-3166 8 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Uterus
Ligands
Androgen Receptors
Progesterone Receptors
Estrogen Receptor Modulators
Cells
Breast Neoplasms
Cell Line
Growth

Responses to Pure Antiestrogens (ICI 164384, ICI182780) in Estrogen‐Sensitive and‐Resistant Experimental and Clinical Breast Cancer

NICHOLSON, R. I., GEE, J. M. W., MANNING, D. L., WAKELING, A. E., MONTANO, M. M. & Katzenellenbogen, B. S., Jun 1995, In : Annals of the New York Academy of Sciences. 761, 1, p. 148-163 16 p.

Research output: Contribution to journalArticle

Reversal of endocrine resistance in breast cancer: Interrelationships among 14-3-3ζ, FOXM1, and a gene signature associated with mitosis

Bergamaschi, A., Christensen, B. L. & Katzenellenbogen, B. S., Jun 29 2011, In : Breast Cancer Research. 13, 3, R70.

Research output: Contribution to journalArticle

Mitosis
Breast Neoplasms
Estrogen Receptors
Genes
Aurora Kinase B

Salicylaldoximes and anthranylaldoximes as alternatives to phenol-based estrogen receptor ligands

Minutolo, F., Bertini, S., Martinelli, A., Ortore, G., Placanica, G., Prota, G., Rapposelli, S., Tuccinardi, T., Sheng, S., Carlson, K. E., Katzenellenbogen, B. S., Katzenellenbogen, J. A. & Macchia, M., Jun 24 2006, In : Arkivoc. 2006, 8, p. 83-94 12 p.

Research output: Contribution to journalArticle

Phenol
Estrogen Receptors
Ligands
Estrogens
Oximes

Science Signaling podcast for 24 May 2016: Designer estrogens

Katzenellenbogen, B. S., Katzenellenbogen, J. A., Madak-Erdogan, Z. & Van hook, A. M., May 24 2016, In : Science Signaling. 9, 429, pc13.

Research output: Contribution to journalReview article

Webcasts
Estrogens
Metabolism
Estradiol Congeners
Bone

Selective Estrogen Receptor Modulators: Discrimination of Agonistic versus Antagonistic Activities by Gene Expression Profiling in Breast Cancer Cells

Frasor, J., Stossi, F., Danes, J. M., Komm, B., Lyttle, C. R. & Katzenellenbogen, B. S., Feb 15 2004, In : Cancer Research. 64, 4, p. 1522-1533 12 p.

Research output: Contribution to journalArticle

Selective Estrogen Receptor Modulators
Gene Expression Profiling
Breast Neoplasms
Tamoxifen
Estrogen Receptors

Selective Nonnuclear Estrogen Receptor Activation Decreases Stroke Severity and Promotes Functional Recovery in Female Mice

Selvaraj, U. M., Zuurbier, K. R., Whoolery, C. W., Plautz, E. J., Chambliss, K. L., Kong, X., Zhang, S., Kim, S. H., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Mineo, C., Shaul, P. W. & Stowe, A. M., Jan 1 2018, In : Endocrinology. 159, 11, p. 3848-3859 12 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Estrogens
Middle Cerebral Artery Infarction
Stroke
Uterine Neoplasms

Selective recognition of distinct classes of coactivators by a ligand-inducible activation domain

Acevedo, M. L., Lee, K. C., Stender, J. D., Katzenellenbogen, B. S. & Kraus, W. L., Mar 5 2004, In : Molecular cell. 13, 5, p. 725-738 14 p.

Research output: Contribution to journalArticle

Mediator Complex
Cytoplasmic and Nuclear Receptors
Furylfuramide
Ligands
Estrogen Receptor beta

Some properties of silkmoth moulting gel and moulting fluid

Katzenellenbogen, B. S. & Kafatos, F. C., Dec 1970, In : Journal of insect physiology. 16, 12, p. 2241-2256 16 p.

Research output: Contribution to journalArticle

Molting
Bombyx
molting
Gels
gels

Spatial mapping of juxtacrine axo-glial interactions identifies novel molecules in peripheral myelination

Poitelon, Y., Bogni, S., Matafora, V., Della-Flora Nunes, G., Hurley, E., Ghidinelli, M., Katzenellenbogen, B. S., Taveggia, C., Silvestri, N., Bachi, A., Sannino, A., Wrabetz, L. & Feltri, M. L., Sep 18 2015, In : Nature communications. 6, 8303.

Research output: Contribution to journalArticle

Neuroglia
axons
Molecules
molecules
interactions

Stilbestrols and stilbestrol derivatives: Estrogenic potency and temporal relationships between estrogen receptor binding and uterine growth

Katzenellenbogen, B. S., Iwamoto, H. S., Heiman, D. F., Lan, N. C. & Katzenellenbogen, J. A., Jan 1 1978, In : Molecular and Cellular Endocrinology. 10, 1, p. 103-113 11 p.

Research output: Contribution to journalArticle

Diethylstilbestrol
Estrogen Receptors
Derivatives
Growth
Cytoplasmic and Nuclear Receptors
Insulin-Like Growth Factor I
Estrogen Receptors
Cyclic AMP
Estrogens
Phosphorylation

Structural Analysis of Covalently Labeled Estrogen Receptors by Limited Proteolysis and Monoclonal Antibody Reactivity

Katzenellenbogen, B. S., Greene, G. L., Elliston, J. F., Monsma, F. J., Springer, P. A. & Ziegler, Y. S., Jan 1 1987, In : Biochemistry. 26, 8, p. 2364-2373 10 p.

Research output: Contribution to journalArticle

Proteolysis
Structural analysis
Estrogen Receptors
Monoclonal Antibodies
Rats

Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism

Shiau, A. K., Barstad, D., Radek, J. T., Meyers, M. J., Nettles, K. W., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Agard, D. A. & Greene, G. L., May 13 2002, In : Nature Structural Biology. 9, 5, p. 359-364 6 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Ligands
Conformations
Association reactions
Enantiomers

Structurally novel antiestrogens elicit differential responses from constitutively active mutant estrogen receptors in breast cancer cells and tumors

Zhao, Y., Laws, M. J., Guillen, V. S., Ziegler, Y., Min, J., Sharma, A., Kim, S. H., Chu, D., Park, B. H., Oesterreich, S., Mao, C., Shapiro, D. J., Nettles, K. W., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Oct 15 2017, In : Cancer Research. 77, 20, p. 5602-5613 12 p.

Research output: Contribution to journalArticle

Estrogen Receptor Modulators
Estrogen Receptors
Breast Neoplasms
Neoplasms
Inbred NOD Mouse
Estrogen Receptors
Yeasts
Ligands
Bacteria
Amino Acids

Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance

Katzenellenbogen, J. A., Mayne, C. G., Katzenellenbogen, B. S., Greene, G. L. & Chandarlapaty, S., Jun 1 2018, In : Nature Reviews Cancer. 18, 6, p. 377-388 12 p.

Research output: Contribution to journalReview article

Estrogen Receptors
Ligands
Mutation
Androgen Receptors
Breast Neoplasms
Mutagenesis
Estrogen Receptors
Yeast
Screening
Yeasts

Structure-function relationships in estrogen receptors and the characterization of novel selective estrogen receptor modulators with unique pharmacological profiles

Katzenellenbogen, B. S., Sun, J., Harrington, W. R., Kraichely, D. M., Ganessunker, D. & Katzenellenbogen, J. A., Jan 1 2001, In : Annals of the New York Academy of Sciences. 949, p. 6-15 10 p.

Research output: Contribution to journalArticle

Selective Estrogen Receptor Modulators
Estrogen Receptor alpha
Estrogen Receptors
Pharmacology
Ligands

Structure-guided optimization of estrogen receptor binding affinity and antagonist potency of pyrazolopyrimidines with basic side chains

Zhou, H. B., Sheng, S., Compton, D. R., Kim, Y., Joachimiak, A., Sharma, S., Carlson, K. E., Katzenellenbogen, B. S., Nettles, K. W., Greene, G. L. & Katzenellenbogen, J. A., Jan 25 2007, In : Journal of Medicinal Chemistry. 50, 2, p. 399-403 5 p.

Research output: Contribution to journalArticle

Pyrimidines
Estrogen Receptors
Ligands
Estrogen Receptor Antagonists

Suppression of FOXM1 activities and breast cancer growth in vitro and in vivo by a new class of compounds

Ziegler, Y., Laws, M. J., Sanabria Guillen, V., Kim, S. H., Dey, P., Smith, B. P., Gong, P., Bindman, N., Zhao, Y., Carlson, K., Yasuda, M. A., Singh, D., Li, Z., El-Ashry, D., Madak-Erdogan, Z., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Dec 1 2019, In : npj Breast Cancer. 5, 1, 45.

Research output: Contribution to journalArticle

Open Access
Breast Neoplasms
Growth
Triple Negative Breast Neoplasms
Gene Ontology
Proteasome Endopeptidase Complex
Estrogen Receptors
Protein Kinases
Estradiol
Chloramphenicol O-Acetyltransferase
1-Methyl-3-isobutylxanthine

Synergistic activation of the serotonin-1A receptor by nuclear factor-κB and estrogen

Wissink, S., Van Der Burg, B., Katzenellenbogen, B. S. & Van Der Saag, P. T., May 1 2001, In : Molecular Endocrinology. 15, 4, p. 543-552 10 p.

Research output: Contribution to journalArticle

Receptor, Serotonin, 5-HT1A
Estrogens
Estrogen Receptors
Aptitude
Estrogen Receptor Modulators

Synthesis and biological evaluation of a novel series of furans: Ligands selective for estrogen receptor α

Mortensen, D. S., Rodriguez, A. L., Carlson, K. E., Sun, J., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Nov 8 2001, In : Journal of Medicinal Chemistry. 44, 23, p. 3838-3848 11 p.

Research output: Contribution to journalArticle

Furans
Estrogen Receptors
Ligands
Thiophenes
Pyrroles

Synthesis and evaluation of estrogen receptor ligands with bridged oxabicyclic cores containing a diarylethylene motif: Estrogen antagonists of unusual structure

Zhou, H. B., Comninos, J. S., Stossi, F., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Nov 17 2005, In : Journal of Medicinal Chemistry. 48, 23, p. 7261-7274 14 p.

Research output: Contribution to journalArticle

Estrogen Antagonists
Estrogen Receptors
Ligands
Transcription
Non-Steroidal Estrogens
Estrous Cycle
Estrogens
Proteins
Uterus
Estrus

Tamoxifen antiestrogens. A comparison of the activity, pharmacokinetics, and metabolic activation of the cis and trans isomers of tamoxifen

Robertson, D. W., Katzenellenbogen, J. A., Long, D. J., Rorke, E. A. & Katzenellenbogen, B. S., Jan 1982, In : Journal of Steroid Biochemistry. 16, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Estrogen Receptor Modulators
Tamoxifen
Isomers
Chemical activation

Tamoxifen aziridines: Effective inactivators of the estrogen receptor

Robertson, D. W., Wei, L. L., Hayes, J. R., Carlson, K. E., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Oct 1981, In : Endocrinology. 109, 4, p. 1298-1300 3 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Breast Neoplasms
Uterine Neoplasms
Estrogen Receptor Modulators
Tamoxifen

Tamoxifen downregulation of miR-451 increases 14-3-3ζ and promotes breast cancer cell survival and endocrine resistance

Bergamaschi, A. & Katzenellenbogen, B. S., Jan 5 2012, In : Oncogene. 31, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

Tamoxifen
MicroRNAs
Cell Survival
Down-Regulation
Breast Neoplasms
Estriol
Uterus
Hormones
Weights and Measures
Ether

The activation function-1 of estrogen receptor alpha prevents arterial neointima development through a direct effect on smooth muscle cells

Smirnova, N. F., Fontaine, C., Buscato, M., Lupieri, A., Vinel, A., Valera, M. C., Guillaume, M., Malet, N., Foidart, J. M., Raymond-Letron, I., Lenfant, F., Gourdy, P., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Laffargue, M. & Arnal, J. F., Oct 9 2015, In : Circulation Research. 117, 9, p. 770-777 8 p.

Research output: Contribution to journalArticle

Neointima
Estrogen Receptor alpha
Estrogen Receptors
Smooth Muscle Myocytes
Vascular Smooth Muscle

The androgen derivative 5α-androstane-3β,17β-diol inhibits prostate cancer cell migration through activation of the estrogen receptor β subtype

Guerini, V., Sau, D., Scaccianoce, E., Rusmini, P., Ciana, P., Maggi, A., Martini, P. G. V., Katzenellenbogen, B. S., Martini, L., Motta, M. & Poletti, A., Jun 15 2005, In : Cancer Research. 65, 12, p. 5445-5453 9 p.

Research output: Contribution to journalArticle

Androstane-3,17-diol
Estrogen Receptors
Androgens
Cell Movement
Prostatic Neoplasms

The anticancer potential of steroidal saponin, dioscin, isolated from wild yam (Dioscorea villosa) root extract in invasive human breast cancer cell line MDA-MB-231 in vitro

Aumsuwan, P., Khan, S. I., Khan, I. A., Ali, Z., Avula, B., Walker, L. A., Shariat-Madar, Z., Helferich, W. G., Katzenellenbogen, B. S. & Dasmahapatra, A. K., Feb 1 2016, In : Archives of Biochemistry and Biophysics. 591, p. 98-110 13 p.

Research output: Contribution to journalArticle

Dioscorea
Saponins
Cells
Breast Neoplasms
Cell Line

The Capacity of the Antiestrogen CI-628 to Activate the Estrogen Receptor in Vitro

De Boer, W. D., Notides, A. C., Katzenellenbogen, B. S., Hayes, J. R. & Katzenellenbogen, J. A., Jan 1981, In : Endocrinology. 108, 1, p. 206-212 7 p.

Research output: Contribution to journalArticle

Nitromifene
Estrogen Receptor Modulators
Estrogen Receptors
Estradiol Receptors
Estradiol
Estrogen Antagonists
Estrogen Receptor Modulators
Estrogen Receptors
Estrogens
Hormones

The coregulator, repressor of estrogen receptor activity (REA), is a crucial regulator of the timing and magnitude of uterine decidualization

Zhao, Y., Park, S., Bagchi, M. K., Taylor, R. N. & Katzenellenbogen, B. S., Mar 1 2013, In : Endocrinology. 154, 3, p. 1349-1360 12 p.

Research output: Contribution to journalArticle

Stromal Cells
Estrogen Receptors
Pregnancy Maintenance
Interleukin-11
Janus Kinases
Estrogen Receptor Modulators
Progesterone Receptors
Estrogen Receptors
Estrogens
Breast Neoplasms

The effects of the phytoestrogen, coumestrol, on gonadotropin-releasing hormone (GnRH) mRNA expression in GT1-7 GnRH neurones

Bowe, J., Li, X. F., Sugden, D., Katzenellenbogen, J. A., Katzenellenbogen, B. S. & O'Byrne, K. T., Feb 1 2003, In : Journal of Neuroendocrinology. 15, 2, p. 105-108 4 p.

Research output: Contribution to journalArticle

Coumestrol
Phytoestrogens
Gonadotropin-Releasing Hormone
Neurons
Messenger RNA

The estrogen receptor: A structure-based approach to the design of new specific hormone-receptor combinations

Tedesco, R., Thomas, J. A., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Apr 25 2001, In : Chemistry and Biology. 8, 3, p. 277-287 11 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Hormones
Ligands
Transgenes
Reporter Genes

The estrogen receptor enhances AP-1 activity by two distinct mechanisms with different requirements for receptor transactivation functions

Webb, P., Nguyen, P., Valentine, C., Lopez, G. N., Kwok, G. R., McInerney, E., Katzenellenbogen, B. S., Enmark, E., Gustafsson, J. Å., Nilsson, S. & Kushner, P. J., Jan 1 1999, In : Molecular Endocrinology. 13, 10, p. 1672-1685 14 p.

Research output: Contribution to journalArticle

Transcription Factor AP-1
Estrogen Receptors
Transcriptional Activation
Estrogens
Furylfuramide

The estrogen-regulated transcription factor PITX1 coordinates gene-specific regulation by estrogen receptor-alpha in breast cancer cells

Stender, J. D., Stossi, F., Funk, C. C., Charn, T. H., Barnett, D. H. & Katzenellenbogen, B. S., Oct 1 2011, In : Molecular Endocrinology. 25, 10, p. 1699-1709 11 p.

Research output: Contribution to journalArticle

Estrogen Receptor alpha
Estrogen Receptors
Estrogens
Transcription Factors
Breast Neoplasms
Forkhead Transcription Factors
Neoplastic Stem Cells
Estrogen Receptors
Breast Neoplasms
Gene Regulatory Networks
Fractionation
Estrogen Receptors
Chromatin
Rats
Micrococcal Nuclease
NAD(P)H Dehydrogenase (Quinone)
Estrogen Receptor Modulators
Estrogen Receptors
Genes
Antioxidant Response Elements

Therapeutic Targeting in the Estrogen Receptor Hormonal Pathway

Katzenellenbogen, B. S. & Frasor, J., Feb 2004, In : Seminars in Oncology. 31, 1 SUPPL. 3, p. 28-38 11 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Breast Neoplasms
Tamoxifen
Therapeutics
Estrogens

The roles of membrane estrogen receptor subtypes in modulating dopamine transporters in PC-12 cells

Alyea, R. A., Laurence, S. E., Kim, S. H., Katzenellenbogen, B. S., Katzenellenbogen, J. A. & Watson, C. S., Aug 1 2008, In : Journal of Neurochemistry. 106, 4, p. 1525-1533 9 p.

Research output: Contribution to journalArticle

Dopamine Plasma Membrane Transport Proteins
Estrogen Receptors
Dopamine
Membranes
G-Protein-Coupled Receptors