Benita S Katzenellenbogen

2016

Multiple beneficial roles of repressor of estrogen receptor activity (REA) in suppressing the progression of endometriosis

Zhao, Y., Chen, Y., Kuang, Y., Bagchi, M. K., Taylor, R. N., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Feb 2016, In: Endocrinology. 157, 2, p. 900-912 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Nonnuclear estrogen receptor activation improves hepatic steatosis in female mice

Chambliss, K. L., Barrera, J., Umetani, M., Umetani, J., Kim, S. H., Madak-Erdogan, Z., Huang, L., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Mineo, C. & Shaul, P. W., 2016, In: Endocrinology. 157, 10, p. 3731-3741 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

OCT-4: A novel estrogen receptor-α collaborator that promotes tamoxifen resistance in breast cancer cells

Bhatt, S., Stender, J. D., Joshi, S., Wu, G. & Katzenellenbogen, B. S., Nov 3 2016, In: Oncogene. 35, 44, p. 5722-5734 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Science Signaling podcast for 24 May 2016: Designer estrogens

Katzenellenbogen, B. S., Katzenellenbogen, J. A., Madak-Erdogan, Z. & Van hook, A. M., May 24 2016, In: Science Signaling. 9, 429, pc13.

Research output: Contribution to journal › Review article › peer-review

The anticancer potential of steroidal saponin, dioscin, isolated from wild yam (Dioscorea villosa) root extract in invasive human breast cancer cell line MDA-MB-231 in vitro

Aumsuwan, P., Khan, S. I., Khan, I. A., Ali, Z., Avula, B., Walker, L. A., Shariat-Madar, Z., Helferich, W. G., Katzenellenbogen, B. S. & Dasmahapatra, A. K., Feb 1 2016, In: Archives of Biochemistry and Biophysics. 591, p. 98-110 13 p.

Research output: Contribution to journal › Article › peer-review

2015

Dual suppression of estrogenic and inflammatory activities for targeting of endometriosis

Zhao, Y., Gong, P., Chen, Y., Nwachukwu, J. C., Srinivasan, S., Ko, C. M., Bagchi, M. K., Taylor, R. N., Korach, K. S., Nettles, K. W., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Jan 21 2015, In: Science Translational Medicine. 7, 271, 271ra9.

Research output: Contribution to journal › Article › peer-review

Open Access

Highly selective salicylketoxime-based estrogen receptor β agonists display antiproliferative activities in a glioma model

Paterni, I., Bertini, S., Granchi, C., Tuccinardi, T., Macchia, M., Martinelli, A., Caligiuri, I., Toffoli, G., Rizzolio, F., Carlson, K. E., Katzenellenbogen, B. S., Katzenellenbogen, J. A. & Minutolo, F., Feb 12 2015, In: Journal of Medicinal Chemistry. 58, 3, p. 1184-1194 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Ligand accessibility and bioactivity of a hormone-dendrimer conjugate depend on pH and pH history

Kim, S. H., Madak-Erdogan, Z., Bae, S. C., Carlson, K. E., Mayne, C. G., Granick, S., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Aug 19 2015, In: Journal of the American Chemical Society. 137, 32, p. 10326-10335 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Protective hematopoietic effect of estrogens in a mouse model of thrombosis: Respective roles of nuclear versus membrane estrogen receptor α

Valera, M. C., Fontaine, C., Lenfant, F., Cabou, C., Guillaume, M., Smirnova, N., Kim, S. H., Chambon, P., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Payrastre, B. & Arnal, J. F., Nov 2015, In: Endocrinology. 156, 11, p. 4293-4301 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Spatial mapping of juxtacrine axo-glial interactions identifies novel molecules in peripheral myelination

Poitelon, Y., Bogni, S., Matafora, V., Della-Flora Nunes, G., Hurley, E., Ghidinelli, M., Katzenellenbogen, B. S., Taveggia, C., Silvestri, N., Bachi, A., Sannino, A., Wrabetz, L. & Feltri, M. L., Sep 18 2015, In: Nature communications. 6, 8303.

Research output: Contribution to journal › Article › peer-review

Open Access

The activation function-1 of estrogen receptor alpha prevents arterial neointima development through a direct effect on smooth muscle cells

Smirnova, N. F., Fontaine, C., Buscato, M., Lupieri, A., Vinel, A., Valera, M. C., Guillaume, M., Malet, N., Foidart, J. M., Raymond-Letron, I., Lenfant, F., Gourdy, P., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Laffargue, M. & Arnal, J. F., Oct 9 2015, In: Circulation Research. 117, 9, p. 770-777 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2014

Endocrine Society 2014 Laureate Awards

Gustafsson, J. A., Katzenellenbogen, B., Jameson, J. L., Roth, J., Melmed, S., McDonnell, D., Wartofsky, L., Crowley, W. F., Griz, L. H. E., Becker, C., Moore, D. D., Drucker, D., Singh, N. & O'Malley, B., Oct 1 2014, In: Hormones & cancer. 5, 5, p. 339-355 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Estrogen-induced CCN1 Is critical for establishment of endometriosis-like lesions in mice

Zhao, Y., Li, Q., Katzenellenbogen, B. S., Lau, L. F., Taylor, R. N., Bagchi, I. C. & Bagchi, M. K., 2014, In: Molecular Endocrinology. 28, 12, p. 1934-1947 14 p.

Research output: Contribution to journal › Article › peer-review

Estrogen receptor-mediated transcription involves the activation of multiple kinase pathways in neuroblastoma cells

Clark, S., Rainville, J., Zhao, X., Katzenellenbogen, B. S., Pfaff, D. & Vasudevan, N., 2014, In: Journal of Steroid Biochemistry and Molecular Biology. 139, p. 45-53 9 p.

Research output: Contribution to journal › Article › peer-review

Evaluation of wild yam (Dioscorea villosa) root extract as a potential epigenetic agent in breast cancer cells

Aumsuwan, P., Khan, S. I., Khan, I. A., Avula, B., Walker, L. A., Helferich, W. G., Katzenellenbogen, B. S. & Dasmahapatra, A. K., Jan 2014, In: In Vitro Cellular and Developmental Biology - Animal. 51, 1, p. 59-71 13 p.

Research output: Contribution to journal › Article › peer-review

Highly sensitive quantitative imaging for monitoring single cancer cell growth kinetics and drug response

Mir, M., Bergamaschi, A., Katzenellenbogen, B. S. & Popescu, G., Feb 18 2014, In: PloS one. 9, 2, e89000.

Research output: Contribution to journal › Article › peer-review

Integration of molecular profiling and chemical imaging to elucidate fibroblast-microenvironment impact on cancer cell phenotype and endocrine resistance in breast cancer

Holton, S. E., Bergamaschi, A., Katzenellenbogen, B. S. & Bhargava, R., May 9 2014, In: PloS one. 9, 5, e96878.

Research output: Contribution to journal › Article › peer-review

Novel roles for ERK5 and cofilin as critical mediators linking ERα-driven transcription, actin reorganization, and invasiveness in breast cancer

Madak-Erdogan, Z., Ventrella, R., Petry, L. & Katzenellenbogen, B. S., May 2014, In: Molecular Cancer Research. 12, 5, p. 714-727 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

The forkhead transcription factor FOXM1 promotes endocrine resistance and invasiveness in estrogen receptor-positive breast cancer by expansion of stem-like cancer cells

Bergamaschi, A., Madak-Erdogan, Z., Kim, Y. J., Choi, Y. L., Lu, H. & Katzenellenbogen, B. S., 2014, In: Breast Cancer Research. 16, 1, 436.

Research output: Contribution to journal › Article › peer-review

Open Access

The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor α modulation, uncoupling nuclear and membrane activation

Abot, A., Fontaine, C., Buscato, M., Solinhac, R., Flouriot, G., Fabre, A., Drougard, A., Rajan, S., Laine, M., Milon, A., Muller, I., Henrion, D., Adlanmerini, M., Valéra, M. C., Gompel, A., Gerard, C., Péqueux, C., Mestdagt, M., Raymond-Letron, I. & Knauf, C. & 9 others, Ferriere, F., Valet, P., Gourdy, P., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Lenfant, F., Greene, G. L., Foidart, J. M. & Arnal, J. F., Oct 1 2014, In: EMBO Molecular Medicine. 6, 10, p. 1328-1346 19 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Transcriptomic analysis identifies gene networks regulated by estrogen receptor α (ERα) and ERβ that control distinct effects of different botanical estrogens

Gong, P., Madak-Erdogan, Z., Li, J., Cheng, J., Greenlief, C. M., Helferich, W., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., 2014, In: Nuclear receptor signaling. 12, p. e001

Research output: Contribution to journal › Article › peer-review

Open Access

2013

14-3-3ζ as a predictor of early time to recurrence and distant metastasis in hormone receptor-positive and -negative breast cancers

Bergamaschi, A., Frasor, J., Borgen, K., Stanculescu, A., Johnson, P., Rowland, K., Wiley, E. L. & Katzenellenbogen, B. S., Feb 2013, In: Breast Cancer Research and Treatment. 137, 3, p. 689-696 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

A MicroRNA196a2* and TP63 Circuit Regulated by Estrogen Receptor-α and ERK2 that Controls Breast Cancer Proliferation and Invasiveness Properties

Kim, K., Madak-Erdogan, Z., Ventrella, R. & Katzenellenbogen, B. S., Apr 2013, In: Hormones and Cancer. 4, 2, p. 78-91 14 p.

Research output: Contribution to journal › Article › peer-review

Integrative genomics of gene and metabolic regulation by estrogen receptors α and β, and their coregulators

Madak-Erdogan, Z., Charn, T. H., Jiang, Y., Liu, E. T., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., 2013, In: Molecular Systems Biology. 9, 201328.

Research output: Contribution to journal › Article › peer-review

Mechanisms enforcing the estrogen receptor β selectivity of botanical estrogens

Jiang, Y., Gong, P., Madak-Erdogan, Z., Martin, T., Jeyakumar, M., Carlson, K., Khan, I., Smillie, T. J., Chittiboyina, A. G., Rotte, S. C. K., Helferich, W. G., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Nov 2013, In: FASEB Journal. 27, 11, p. 4406-4418 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Non-nuclear-initiated actions of the estrogen receptor protect cortical bone mass

Bartell, S. M., Han, L., Kim, H. N., Kim, S. H., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Chambliss, K. L., Shaul, P. W., Roberson, P. K., Weinstein, R. S., Jilka, R. L., Almeida, M. & Manolagas, S. C., Apr 1 2013, In: Molecular Endocrinology. 27, 4, p. 649-656 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

The coregulator, repressor of estrogen receptor activity (REA), is a crucial regulator of the timing and magnitude of uterine decidualization

Zhao, Y., Park, S., Bagchi, M. K., Taylor, R. N. & Katzenellenbogen, B. S., Mar 1 2013, In: Endocrinology. 154, 3, p. 1349-1360 12 p.

Research output: Contribution to journal › Article › peer-review

2012

Aryl hydrocarbon receptor modulation of estrogen receptor α-mediated gene regulation by a multimeric chromatin complex involving the two receptors and the coregulator RIP140

Madak-Erdogan, Z. & Katzenellenbogen, B. S., Feb 2012, In: Toxicological Sciences. 125, 2, p. 401-411 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Macrophage-elicited loss of estrogen receptor-α in breast cancer cells via involvement of MAPK and c-Jun at the ESR1 genomic locus

Stossi, F., Madak-Erdoǧan, Z. & Katzenellenbogen, B. S., Apr 5 2012, In: Oncogene. 31, 14, p. 1825-1834 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Phosphorylation by p38 mitogen-activated protein kinase promotes estrogen receptor α turnover and functional activity via the SCF^skp2 proteasomal complex

Bhatt, S., Xiao, Z., Meng, Z. & Katzenellenbogen, B. S., May 2012, In: Molecular and cellular biology. 32, 10, p. 1928-1943 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Tamoxifen downregulation of miR-451 increases 14-3-3ζ and promotes breast cancer cell survival and endocrine resistance

Bergamaschi, A. & Katzenellenbogen, B. S., Jan 5 2012, In: Oncogene. 31, 1, p. 39-47 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Uterine development and fertility are dependent on gene dosage of the nuclear receptor coregulator REA

Park, S., Yoon, S., Zhao, Y., Park, S. E., Liao, L., Xu, J., Lydon, J. P., DeMayo, F. J., O'Malley, B. W., Bagchi, M. K. & Katzenellenbogen, B. S., Aug 1 2012, In: Endocrinology. 153, 8, p. 3982-3994 13 p.

Research output: Contribution to journal › Article › peer-review

2011

Estrogen receptor β ligands: Recent advances and biomedical applications

Minutolo, F., Macchia, M., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., May 2011, In: Medicinal Research Reviews. 31, 3, p. 364-442 79 p.

Research output: Contribution to journal › Article › peer-review

Estrogen-regulated prohibitin is required for mouse uterine development and adult function

He, B., Kim, T. H., Kommagani, R., Feng, Q., Lanz, R. B., Jeong, J. W., DeMayo, F. J., Katzenellenbogen, B. S., Lydon, J. P. & O'Malley, B. W., Mar 2011, In: Endocrinology. 152, 3, p. 1047-1056 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Genomic collaboration of estrogen receptor α and extracellular signal-regulated kinase 2 in regulating gene and proliferation programs

Madak-Erdogan, Z., Lupien, M., Stossi, F., Brown, M. & Katzenellenbogen, B. S., Jan 2011, In: Molecular and cellular biology. 31, 1, p. 226-236 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Repressor of Estrogen Receptor Activity (REA) is essential for mammary gland morphogenesis and functional activities: Studies in conditional knockout mice

Park, S., Zhao, Y., Yoon, S., Xu, J., Liao, L., Lydon, J., DeMayo, F., O'Malley, B. W. & Katzenellenbogen, B. S., Nov 2011, In: Endocrinology. 152, 11, p. 4336-4349 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Reversal of endocrine resistance in breast cancer: Interrelationships among 14-3-3ζ, FOXM1, and a gene signature associated with mitosis

Bergamaschi, A., Christensen, B. L. & Katzenellenbogen, B. S., Jun 29 2011, In: Breast Cancer Research. 13, 3, R70.

Research output: Contribution to journal › Article › peer-review

Open Access

The estrogen-regulated transcription factor PITX1 coordinates gene-specific regulation by estrogen receptor-alpha in breast cancer cells

Stender, J. D., Stossi, F., Funk, C. C., Charn, T. H., Barnett, D. H. & Katzenellenbogen, B. S., Oct 1 2011, In: Molecular Endocrinology. 25, 10, p. 1699-1709 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2010

Activation of ERα is necessary for estradiol's anorexigenic effect in female rats

Santollo, J., Katzenellenbogen, B. S., Katzenellenbogen, J. A. & Eckel, L. A., Nov 2010, In: Hormones and Behavior. 58, 5, p. 872-877 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Characterization of the pharmacophore properties of novel selective estrogen receptor downregulators (SERDs)

Kieser, K. J., Kim, D. W., Carlson, K. E., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Apr 22 2010, In: Journal of Medicinal Chemistry. 53, 8, p. 3320-3329 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Extranuclear estrogen receptor-α stimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis

Wong, W. P. S., Tiano, J. P., Liu, S., Hewitt, S. C., Le May, C., Dalle, S., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Korach, K. S. & Mauvais-Jarvis, F., Jul 20 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 29, p. 13057-13062 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Genome-wide analysis of estrogen receptor α DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation

Stender, J. D., Kim, K., Charn, T. H., Komm, B., Chang, K. C. N., Kraus, W. L., Benner, C., Glass, C. K. & Katzenellenbogen, B. S., Aug 2010, In: Molecular and cellular biology. 30, 16, p. 3943-3955 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Genome-wide dynamics of chromatin binding of estrogen receptors α and β: Mutual restriction and competitive site selection

Charn, T. H., Liu, E. T. B., Chang, E. C., Lee, Y. K., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Jan 2010, In: Molecular Endocrinology. 24, 1, p. 47-59 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Non-nuclear estrogen receptor α signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice

Chambliss, K. L., Wu, Q., Oltmann, S., Konaniah, E. S., Umetani, M., Korach, K. S., Thomas, G. D., Mineo, C., Yuhanna, I. S., Kim, S. H., Madak-Erdogan, Z., Maggi, A., Dineen, S. P., Roland, C. L., Hui, D. Y., Brekken, R. A., Katzenellenbogen, J. A., Katzenellenbogen, B. S. & Shaul, P. W., Jul 1 2010, In: Journal of Clinical Investigation. 120, 7, p. 2319-2330 12 p.

Research output: Contribution to journal › Article › peer-review

Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects

Marshall, G. M., Gherardi, S., Xu, N., Neiron, Z., Trahair, T., Scarlett, C. J., Chang, D. K., Liu, P. Y., Jankowski, K., Iraci, N., Haber, M., Norris, M. D., Keating, J., Sekyere, E., Jonquieres, G., Stossi, F., Katzenellenbogen, B. S., Biankin, A. V., Perini, G. & Liu, T., Nov 4 2010, In: Oncogene. 29, 44, p. 5957-5968 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2009

A case of premature thelarche with no central cause or genetic variants within the estrogen receptor signaling pathway

Hartmaier, R. J., Walenkamp, M. J. E., Richter, A. S., Wang, J., Katzenellenbogen, B. S., Oesterreich, S. & Wit, J. M., 2009, In: Journal of Pediatric Endocrinology and Metabolism. 22, 8, p. 751-758 8 p.

Research output: Contribution to journal › Article › peer-review

Analogs of methyl-piperidinopyrazole (MPP): Antiestrogens with estrogen receptor α selective activity

Zhou, H. B., Carlson, K. E., Stossi, F., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Jan 1 2009, In: Bioorganic and Medicinal Chemistry Letters. 19, 1, p. 108-110 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Bibenzyl- and stilbene-core compounds with non-polar linker atom substituents as selective ligands for estrogen receptor beta

Waibel, M., De Angelis, M., Stossi, F., Kieser, K. J., Carlson, K. E., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Sep 2009, In: European Journal of Medicinal Chemistry. 44, 9, p. 3412-3424 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Distinct roles for AF-1 and -2 of ER-alpha in regulation of MMP-13 promoter activity

Achari, Y., Lu, T., Katzenellenbogen, B. S. & Hart, D. A., Mar 2009, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1792, 3, p. 211-220 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Estrogen receptor alpha represses transcription of early target genes via p300 and CtBP1

Stossi, F., Madak-Erdogan, Z. & Katzenellenbogen, B. S., Apr 2009, In: Molecular and cellular biology. 29, 7, p. 1749-1759 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Benita S Katzenellenbogen

Research output

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