Benita S Katzenellenbogen

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Research Output

Article

Structure-function relationships in estrogen receptors and the characterization of novel selective estrogen receptor modulators with unique pharmacological profiles

Katzenellenbogen, B. S., Sun, J., Harrington, W. R., Kraichely, D. M., Ganessunker, D. & Katzenellenbogen, J. A., 2001, In : Annals of the New York Academy of Sciences. 949, p. 6-15 10 p.

Research output: Contribution to journalArticle

Structure-guided optimization of estrogen receptor binding affinity and antagonist potency of pyrazolopyrimidines with basic side chains

Zhou, H. B., Sheng, S., Compton, D. R., Kim, Y., Joachimiak, A., Sharma, S., Carlson, K. E., Katzenellenbogen, B. S., Nettles, K. W., Greene, G. L. & Katzenellenbogen, J. A., Jan 25 2007, In : Journal of Medicinal Chemistry. 50, 2, p. 399-403 5 p.

Research output: Contribution to journalArticle

Suppression of FOXM1 activities and breast cancer growth in vitro and in vivo by a new class of compounds

Ziegler, Y., Laws, M. J., Sanabria Guillen, V., Kim, S. H., Dey, P., Smith, B. P., Gong, P., Bindman, N., Zhao, Y., Carlson, K., Yasuda, M. A., Singh, D., Li, Z., El-Ashry, D., Madak-Erdogan, Z., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Dec 1 2019, In : npj Breast Cancer. 5, 1, 45.

Research output: Contribution to journalArticle

Open Access

Synergistic activation of the serotonin-1A receptor by nuclear factor-κB and estrogen

Wissink, S., Van Der Burg, B., Katzenellenbogen, B. S. & Van Der Saag, P. T., May 1 2001, In : Molecular Endocrinology. 15, 4, p. 543-552 10 p.

Research output: Contribution to journalArticle

Synthesis and biological evaluation of a novel series of furans: Ligands selective for estrogen receptor α

Mortensen, D. S., Rodriguez, A. L., Carlson, K. E., Sun, J., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Nov 8 2001, In : Journal of Medicinal Chemistry. 44, 23, p. 3838-3848 11 p.

Research output: Contribution to journalArticle

Synthesis and evaluation of estrogen receptor ligands with bridged oxabicyclic cores containing a diarylethylene motif: Estrogen antagonists of unusual structure

Zhou, H. B., Comninos, J. S., Stossi, F., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Nov 17 2005, In : Journal of Medicinal Chemistry. 48, 23, p. 7261-7274 14 p.

Research output: Contribution to journalArticle

Tamoxifen antiestrogens. A comparison of the activity, pharmacokinetics, and metabolic activation of the cis and trans isomers of tamoxifen

Robertson, D. W., Katzenellenbogen, J. A., Long, D. J., Rorke, E. A. & Katzenellenbogen, B. S., Jan 1982, In : Journal of Steroid Biochemistry. 16, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

Tamoxifen aziridines: Effective inactivators of the estrogen receptor

Robertson, D. W., Wei, L. L., Hayes, J. R., Carlson, K. E., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Oct 1981, In : Endocrinology. 109, 4, p. 1298-1300 3 p.

Research output: Contribution to journalArticle

Tamoxifen downregulation of miR-451 increases 14-3-3ζ and promotes breast cancer cell survival and endocrine resistance

Bergamaschi, A. & Katzenellenbogen, B. S., Jan 5 2012, In : Oncogene. 31, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

The activation function-1 of estrogen receptor alpha prevents arterial neointima development through a direct effect on smooth muscle cells

Smirnova, N. F., Fontaine, C., Buscato, M., Lupieri, A., Vinel, A., Valera, M. C., Guillaume, M., Malet, N., Foidart, J. M., Raymond-Letron, I., Lenfant, F., Gourdy, P., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Laffargue, M. & Arnal, J. F., Oct 9 2015, In : Circulation Research. 117, 9, p. 770-777 8 p.

Research output: Contribution to journalArticle

The androgen derivative 5α-androstane-3β,17β-diol inhibits prostate cancer cell migration through activation of the estrogen receptor β subtype

Guerini, V., Sau, D., Scaccianoce, E., Rusmini, P., Ciana, P., Maggi, A., Martini, P. G. V., Katzenellenbogen, B. S., Martini, L., Motta, M. & Poletti, A., Jun 15 2005, In : Cancer Research. 65, 12, p. 5445-5453 9 p.

Research output: Contribution to journalArticle

The anticancer potential of steroidal saponin, dioscin, isolated from wild yam (Dioscorea villosa) root extract in invasive human breast cancer cell line MDA-MB-231 in vitro

Aumsuwan, P., Khan, S. I., Khan, I. A., Ali, Z., Avula, B., Walker, L. A., Shariat-Madar, Z., Helferich, W. G., Katzenellenbogen, B. S. & Dasmahapatra, A. K., Feb 1 2016, In : Archives of Biochemistry and Biophysics. 591, p. 98-110 13 p.

Research output: Contribution to journalArticle

The Capacity of the Antiestrogen CI-628 to Activate the Estrogen Receptor in Vitro

De Boer, W. D., Notides, A. C., Katzenellenbogen, B. S., Hayes, J. R. & Katzenellenbogen, J. A., Jan 1981, In : Endocrinology. 108, 1, p. 206-212 7 p.

Research output: Contribution to journalArticle

The coregulator, repressor of estrogen receptor activity (REA), is a crucial regulator of the timing and magnitude of uterine decidualization

Zhao, Y., Park, S., Bagchi, M. K., Taylor, R. N. & Katzenellenbogen, B. S., Mar 1 2013, In : Endocrinology. 154, 3, p. 1349-1360 12 p.

Research output: Contribution to journalArticle

The effects of the phytoestrogen, coumestrol, on gonadotropin-releasing hormone (GnRH) mRNA expression in GT1-7 GnRH neurones

Bowe, J., Li, X. F., Sugden, D., Katzenellenbogen, J. A., Katzenellenbogen, B. S. & O'Byrne, K. T., Feb 1 2003, In : Journal of Neuroendocrinology. 15, 2, p. 105-108 4 p.

Research output: Contribution to journalArticle

The estrogen receptor: A structure-based approach to the design of new specific hormone-receptor combinations

Tedesco, R., Thomas, J. A., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Apr 25 2001, In : Chemistry and Biology. 8, 3, p. 277-287 11 p.

Research output: Contribution to journalArticle

The estrogen receptor enhances AP-1 activity by two distinct mechanisms with different requirements for receptor transactivation functions

Webb, P., Nguyen, P., Valentine, C., Lopez, G. N., Kwok, G. R., McInerney, E., Katzenellenbogen, B. S., Enmark, E., Gustafsson, J. Å., Nilsson, S. & Kushner, P. J., Jan 1 1999, In : Molecular Endocrinology. 13, 10, p. 1672-1685 14 p.

Research output: Contribution to journalArticle

The estrogen-regulated transcription factor PITX1 coordinates gene-specific regulation by estrogen receptor-alpha in breast cancer cells

Stender, J. D., Stossi, F., Funk, C. C., Charn, T. H., Barnett, D. H. & Katzenellenbogen, B. S., Oct 1 2011, In : Molecular Endocrinology. 25, 10, p. 1699-1709 11 p.

Research output: Contribution to journalArticle

Therapeutic Targeting in the Estrogen Receptor Hormonal Pathway

Katzenellenbogen, B. S. & Frasor, J., Feb 2004, In : Seminars in Oncology. 31, 1 SUPPL. 3, p. 28-38 11 p.

Research output: Contribution to journalArticle

The roles of membrane estrogen receptor subtypes in modulating dopamine transporters in PC-12 cells

Alyea, R. A., Laurence, S. E., Kim, S. H., Katzenellenbogen, B. S., Katzenellenbogen, J. A. & Watson, C. S., Aug 1 2008, In : Journal of Neurochemistry. 106, 4, p. 1525-1533 9 p.

Research output: Contribution to journalArticle

The stability of the uterine estrogen receptor when complexed with estrogens or antiestrogens

Pavlik, E. J. & Katzenellenbogen, B. S., 1980, In : Molecular Pharmacology. 18, 3, p. 406-412 7 p.

Research output: Contribution to journalArticle

The tissue-specific effects of different 17β-estradiol doses reveal the key sensitizing role of AF1 domain in ERα activity

Fontaine, C., Buscato, M., Vinel, A., Giton, F., Raymond-Letron, I., Kim, S. H., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Gourdy, P., Milon, A., Flouriot, G., Ohlsson, C., Lenfant, F. & Arnal, J. F., Apr 5 2020, In : Molecular and Cellular Endocrinology. 505, 110741.

Research output: Contribution to journalArticle

The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor α modulation, uncoupling nuclear and membrane activation

Abot, A., Fontaine, C., Buscato, M., Solinhac, R., Flouriot, G., Fabre, A., Drougard, A., Rajan, S., Laine, M., Milon, A., Muller, I., Henrion, D., Adlanmerini, M., Valéra, M. C., Gompel, A., Gerard, C., Péqueux, C., Mestdagt, M., Raymond-Letron, I., Knauf, C. & 9 others, Ferriere, F., Valet, P., Gourdy, P., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Lenfant, F., Greene, G. L., Foidart, J. M. & Arnal, J. F., Oct 1 2014, In : EMBO Molecular Medicine. 6, 10, p. 1328-1346 19 p.

Research output: Contribution to journalArticle

Thyroid hormone can increase estrogen-mediated transcription from a consensus estrogen response element in neuroblastoma cells

Zhao, X., Lorenc, H., Stephenson, H., Wang, Y. J., Witherspoon, D., Katzenellenbogen, B., Pfaff, D. & Vasudevan, N., Mar 29 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 13, p. 4890-4895 6 p.

Research output: Contribution to journalArticle

Transcription activation by the human estrogen receptor subtype β (ERβ) studied with ERβ and ERα receptor chimeras

Mcinerney, E. M., Weis, K. E., Sun, J., Mosselman, S. & Katzenellenbogen, B. S., Jan 1 1998, In : Endocrinology. 139, 11, p. 4513-4522 10 p.

Research output: Contribution to journalArticle

Transcriptional profiling of estrogen-regulated gene expression via estrogen receptor (ER) α or ERβ in human osteosarcoma cells: Distinct and common target genes for these receptors

Stossi, F., Barnett, D. H., Frasor, J., Komm, B., Lyttle, C. R. & Katzenellenbogen, B. S., Jul 1 2004, In : Endocrinology. 145, 7, p. 3473-3486 14 p.

Research output: Contribution to journalArticle

Transcriptional regulation of the human quinone reductase gene by antiestrogen-liganded estrogen receptor-α and estrogen receptor-β

Montano, M. M., Jaiswal, A. K. & Katzenellenbogen, B. S., Sep 25 1998, In : Journal of Biological Chemistry. 273, 39, p. 25443-25449 7 p.

Research output: Contribution to journalArticle

Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects

Marshall, G. M., Gherardi, S., Xu, N., Neiron, Z., Trahair, T., Scarlett, C. J., Chang, D. K., Liu, P. Y., Jankowski, K., Iraci, N., Haber, M., Norris, M. D., Keating, J., Sekyere, E., Jonquieres, G., Stossi, F., Katzenellenbogen, B. S., Biankin, A. V., Perini, G. & Liu, T., Nov 4 2010, In : Oncogene. 29, 44, p. 5957-5968 12 p.

Research output: Contribution to journalArticle

Triarylpyrazoles with basic side chains: Development of pyrazole-based estrogen receptor antagonists

Stauffer, S. R., Huang, Y. R., Aron, Z. D., Coletta, C. J., Sun, J., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Jan 8 2001, In : Bioorganic and Medicinal Chemistry. 9, 1, p. 151-161 11 p.

Research output: Contribution to journalArticle

Uterine development and fertility are dependent on gene dosage of the nuclear receptor coregulator REA

Park, S., Yoon, S., Zhao, Y., Park, S. E., Liao, L., Xu, J., Lydon, J. P., DeMayo, F. J., O'Malley, B. W., Bagchi, M. K. & Katzenellenbogen, B. S., Aug 1 2012, In : Endocrinology. 153, 8, p. 3982-3994 13 p.

Research output: Contribution to journalArticle

Uterine plasminogen activator activity: Modulation by steroid hormones

Kneifel, M. A., Leytus, S. P., Fletcher, E., Weber, T., Mangel, W. F. & Katzenellenbogen, B. S., Aug 1982, In : Endocrinology. 111, 2, p. 493-499 7 p.

Research output: Contribution to journalArticle

Whole-genome cartography of estrogen receptor α binding sites

Lin, C. Y., Vega, V. B., Thomsen, J. S., Zhang, T., Say, L. K., Xie, M., Kuo, P. C., Lipovich, L., Barnett, D. H., Stossi, F., Yeo, A., George, J., Kuznetsov, V. A., Yew, K. L., Tze, H. C., Palanisamy, N., Miller, L. D., Cheung, E., Katzenellenbogen, B. S., Ruan, Y. & 3 others, Bourque, G., Wei, C. L. & Liu, E. T., Jun 2007, In : PLoS genetics. 3, 6, p. 867-885 19 p.

Research output: Contribution to journalArticle

Zearalenones: Characterization of the estrogenic potencies and receptor interactions of a series of fungal β-resorcylic acid lactones

Katzenellenbogen, B. S., Katzenellenbogen, J. A. & Mordecai, D., Jul 1979, In : Endocrinology. 105, 1, p. 33-40 8 p.

Research output: Contribution to journalArticle

Editorial: A new actor in the estrogen receptor drama - Enter ER-β

Katzenellenbogen, B. S. & Korach, K. S., Jan 1 1997, In : Endocrinology. 138, 3, p. 861-862 2 p.

Research output: Contribution to journalEditorial

Review article

Antiestrogens: Mechanisms of action and resistance in breast cancer

Katzenellenbogen, B. S., Montano, M. M., Ekena, K., Herman, M. E. & McInerney, E. M., Jan 1 1997, In : Breast Cancer Research and Treatment. 44, 1, p. 23-38 16 p.

Research output: Contribution to journalReview article

Endocrine treatment in breast cancer: Cure, resistance and beyond

Tryfonidis, K., Zardavas, D., Katzenellenbogen, B. S. & Piccart, M., Nov 1 2016, In : Cancer Treatment Reviews. 50, p. 68-81 14 p.

Research output: Contribution to journalReview article